[{"Action":"inhibit","PerturbationName":"Dasatinib","PubChemCID":"3062316","SMILES":"CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO","Synonyms":"['Dasatinib', '302962-49-8', 'Sprycel', 'Dasatinib anhydrous', 'BMS 354825', 'Dasatinib (anhydrous)', 'dasatinibum', 'N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE', 'anh. dasatinib', 'N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide', 'anhydrous dasatinib', 'dasatinib (anh.)', 'N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide', 'N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide', 'BMS Dasatinib', 'UNII-X78UG0A0RN', 'X78UG0A0RN', 'DTXSID4040979', 'CHEBI:49375', 'NSC732517', 'NSC-759877', '5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-', 'DTXCID2020979', 'BMS-354825 HYDRATE', 'BMS 345825', '5-Thiazolecarboxamide, N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)-1-piperazinyl)-2-methyl-4-pyrimidinyl)amino)-', 'BMS 35482513', 'BMS-354825-03', 'UNII-RBZ1571X5H', 'CHEBI:70839', 'DTXSID50235486', 'n-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)-1,3-thiazole-5-carboxamide', 'NSC 759877', 'DTXCID50157977', 'L01XE06', 'n-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)-1,3-thiazole-5-carboxamide--water (1/1)', 'BMS-354825', 'BMS354825', 'Dasatinib (BMS-354825)', 'CHEMBL1421', 'NSC-732517', 'NCGC00181129-01', 'C22H26ClN7O2S', 'SMR002529551', 'CAS-302962-49-8', '302962-49-8 pound not863127-77-9', 'Dasatinib [USAN:INN]', '1N1', 'MFCD11046566', 'Dasatinib (Standard)', 'Kinome_3650', 'Dasatinib (JAN/INN)', 'DASATINIB [INN]', 'DASATINIB [MI]', 'Sprycel (Bristol Meyers)', 'DASATINIB [WHO-DD]', 'SCHEMBL8226', 'Dasatinib,BMS-354825', 'MLS003915609', 'MLS004774145', 'MLS006010904', 'Dasatinib - Bio-X trade mark', 'GTPL5678', 'BDBM13216', 'cid_3062316', 'Dasatinib (BMS-354825)?', 'EX-A401', '5-Thiazolecarboxamide, monohydrate', 'BCPP000263', 'HMS2043N05', 'HMS3244A05', 'HMS3244A06', 'HMS3244B05', 'HMS3265C19', 'HMS3265C20', 'HMS3265D19', 'HMS3265D20', 'HMS3654K05', 'HMS3744C11', 'Pharmakon1600-01502275', 'BCP01797', 'Tox21_112736', 'HY-10181R', 'NSC759877', 'NSC800087', 's1021', 'AKOS015902363', 'Tox21_112736_1', 'BCP9000589', 'CCG-264779', 'CS-0100', 'DB01254', 'FC36515', 'GS-6548', 'NSC-800087', 'SB17284', 'SDCCGSBI-0061713.P004', 'NCGC00181129-02', 'NCGC00181129-03', 'NCGC00181129-05', 'NCGC00181129-06', 'NCGC00181129-07', 'NCGC00181129-12', 'NCGC00181129-14', 'NCGC00181129-22', 'NCGC00481571-01', '2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide', 'AC-22749', 'BCB03_000715', 'BD300052', 'HY-10181', 'N-(2-chloro-6-methyl-phenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methyl-pyrimidin-4-yl]amino]thiazole-5-carboxamide', 'D5949', 'NS00001968', 'PA-3062316', 'SW208076-5', 'D-3307', 'D03658', 'EN300-123025', 'AB01273956-01', 'AB01273956-02', 'AB01273956_03', 'AR-270/43507994', 'Q419940', 'SR-00000000554', 'SR-00000000554-5', 'BRD-K49328571-001-05-1', 'BRD-K49328571-001-07-7', 'BRD-K49328571-001-15-0', 'BRD-K49328571-001-19-2', 'Z1546610486', 'N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl}amino)-1,3-thiazole-5-carboxamide', 'N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Etoposide","PubChemCID":"36462","SMILES":"C[C@@H]1OC[C@@H]2[C@@H](O1)[C@@H]([C@H]([C@@H](O2)O[C@H]3[C@H]4COC(=O)[C@@H]4[C@@H](C5=CC6=C(C=C35)OCO6)C7=CC(=C(C(=C7)OC)O)OC)O)O","Synonyms":"['etoposide', '33419-42-0', '(-)-Etoposide', 'Zuyeyidal', 'Etoposido', 'Etoposidum', 'Etoposidum [INN-Latin]', 'Etoposide (VP16)', 'VP 16 (pharmaceutical)', 'Sintopozid', 'Vepesid J', 'VP-16-213', 'Etoposido [INN-Spanish]', '4-Demethylepipodophyllotoxin beta-D-ethylideneglucoside', 'NK 171', 'CCRIS 2392', 'DTXSID5023035', 'HSDB 6517', 'UNII-6PLQ3CP4P3', 'EINECS 251-509-1', '6PLQ3CP4P3', \"4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)\", 'EPEG', 'CHEBI:4911', 'Epipodophyllotoxin VP-16213', \"4'-O-Demethyl-1-O-(4,6-O-ethylidene-beta-D-glucopyranosyl)epipodophyllotoxin\", \"Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-beta-D-glucopyranoside)\", \"Epipodophyllotoxin-beta-D-ethyliden-glucoside, 4'-demethyl-\", 'Eposide', 'DTXCID601473876', \"Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside\", \"4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside)\", 'Etoposide [USAN:USP:INN:BAN:JAN]', 'ETOPOSIDE (IARC)', 'ETOPOSIDE [IARC]', 'Etoposidum (INN-Latin)', 'Etoposido (INN-Spanish)', 'ETOPOSIDE (MART.)', 'ETOPOSIDE [MART.]', 'ETOPOSIDE (USP-RS)', 'ETOPOSIDE [USP-RS]', 'ETOPOSIDE (EP IMPURITY)', 'ETOPOSIDE [EP IMPURITY]', 'ETOPOSIDE (EP MONOGRAPH)', 'ETOPOSIDE (USP IMPURITY)', 'ETOPOSIDE [EP MONOGRAPH]', 'ETOPOSIDE [USP IMPURITY]', 'ETOPOSIDE (USP MONOGRAPH)', 'ETOPOSIDE [USP MONOGRAPH]', 'Prestwick 211', 'Etoposide (USAN:USP:INN:BAN:JAN)', 'Demethyl Epipodophyllotoxin Ethylidine Glucoside', \"4'-Demethylepipodophyllotoxin ethylidene-beta-D-glucoside\", 'L01CB01', 'ETOPOSIDE IMPURITY C (EP IMPURITY)', '251-509-1', 'VePesid', 'Toposar', 'trans-Etoposide', 'Lastet', 'VP-16', 'VP 16-213', 'NSC-141540', 'Etoposide (VP-16)', 'VP 16', 'CHEMBL44657', 'NSC 141540', 'Etosid', 'MFCD00869325', \"(5R,5aR,8aR,9S)-9-(((4aR,6R,7R,8R,8aS)-7,8-Dihydroxy-2-methylhexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy)-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one\", '(5S,5aR,8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one', \"(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside\", 'Etopophos (phosphate salt)', 'Etopol', 'Demethylepipodophyllotoxin-beta-D-ethylideneglucoside', 'VP 16213', 'NSC141540', '(10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0^{3,7}.0^{11,15}]hexadeca-1(9),2,7-trien-12-one', \"9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one\", 'SMR000112002', 'VePESID (TN)', \"4'-Demethylepipodophyllotoxin ethylidene-.beta.-D-glucoside\", 'NCGC00016821-01', \"(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside\", 'EVP', \"Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-.beta.-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-\", 'CAS-33419-42-0', 'Etoposide (Standard)', 'Etoposide; VP-16', 'CPD000112002', 'ETOPOSIDE [INN]', 'ETOPOSIDE [JAN]', 'ETOPOSIDE [MI]', 'ETOPOSIDE [HSDB]', 'ETOPOSIDE [USAN]', 'Prestwick3_000396', 'ETOPOSIDE [VANDF]', 'ETOPOSIDE [WHO-DD]', 'ETOPOSIDE [WHO-IP]', 'SCHEMBL4259', 'BSPBio_000611', \"9-((4,6-O-Ethylidene-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, (5R-(5alpha,5abeta,8aalpha,9beta(R*)))-\", \"9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4- hydroxy-3,4-dimethyloxyphenyl)furo (3',4'':6,7) naptho-(2,3-d)-1,3-dioxol-6 (5aH)-one\", 'MLS000049957', 'MLS001074951', 'MLS001424283', 'MLS002153463', 'MLS002207239', 'MLS002222184', 'Etoposide - Bio-X trade mark', 'Etoposide (JP18/USP/INN)', 'BPBio1_000673', 'GTPL6815', 'ETOPOSIDE [ORANGE BOOK]', 'ETOPOSIDUM [WHO-IP LATIN]', 'HMS2052N05', 'HMS2089F14', 'HMS2096O13', 'HMS2232L03', 'HMS3713O13', 'EPE', 'EX-A1207', 'Tox21_110630', 'Tox21_302201', 'BDBM50127140', 'HY-13629R', 's1225', 'Etoposide - CAS 33419-42-0', 'AKOS007930275', 'BCP9000669', 'CCG-101165', 'CS-1774', 'DB00773', 'Etoposide, synthetic, >=98%, powder', 'ME09941', 'NC00415', 'SDCCGSBI-0050405.P002', \"4'-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside\", 'NCGC00179504-02', 'NCGC00255126-01', 'AS-35312', 'BE164434', \"Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 9-((4,6-O-(1R)-ethylidene-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-\", \"Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one-, 9-((4,6-O-ethylidene-beta-D-glucopyranosyl)oxy)5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl), (5R-(5alpha,5abeta,8aalpha,9beta(R*)))-\", 'HY-13629', 'SBI-0051910.P002', 'AB00438905', 'NS00009585', 'EN300-97099', 'C01576', 'D00125', 'AB00438905-17', 'AB00438905-18', 'AB00438905_19', 'Q418817', 'SR-01000763196', 'SR-01000763196-3', 'BRD-K37798499-001-02-5', 'BRD-K37798499-001-05-8', 'BRD-K37798499-001-10-8', 'BRD-K37798499-001-14-0', 'BRD-K37798499-001-18-1', 'BRD-K37798499-001-21-5', 'BRD-K37798499-001-22-3', 'BRD-K37798499-001-25-6', 'BRD-K37798499-001-27-2', '-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside', 'Etoposide, British Pharmacopoeia (BP) Reference Standard', 'Z1304065033', 'Etoposide, European Pharmacopoeia (EP) Reference Standard', 'Etoposide, United States Pharmacopeia (USP) Reference Standard', \"4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-?-D-glucopyranoside)\", '4?-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-b-D-glucopyranoside)', \"4''-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)\", \"4'-DEMETHYLEPIPODOPHYLLOTOXIN 9-(4,6-O-(R)-ETHYLIDENE-.BETA.-D-GLUCOPYRANOSIDE)\", 'Etoposide for system suitability, European Pharmacopoeia (EP) Reference Standard', '(5R,5AR,8aR,9S)-9-(((2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methylhexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy)-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,5a,8a,9-tetrahy', \"(5R,5aR,8aR,9S)-9-(((2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methylhexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy)-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one\", '(5R,5AR,8AR,9S)-9-((4,6-O-((1R)-ETHANE-1,1-DIYL)-.ALPHA.-D-GLUCOPYRANOSYL)OXY)-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-5,8,8A,9-TETRAHYDRO(2)BENZOFURO(5,6-F)(1,3)BENZODIOXOL-6(5AH)-ONE', '(5S,5aR,8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxy-phenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,3]benzodioxol-8-one', \"(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3'',4'':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside\", '121471-01-0', \"9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3'',4'''':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one\", \"FURO(3',4':6,7)NAPHTHO(2,3-D)-1,3-DIOXOL-6(5AH)-ONE-, 9-((4,6-O-ETHYLIDENE-.BETA.-D-GLUCOPYRANOSYL)OXY)5,8,8A,9-TETRAHYDRO-5-(4-HYDROXY-3,5-DIMETHOXYPHENYL), (5R-(5.ALPHA.,5A.BETA.,8A.ALPHA.,9.BETA.(R*)))-\"]","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Tofacitinib","PubChemCID":"9926791","SMILES":"C[C@@H]1CCN(C[C@@H]1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N","Synonyms":"['Tofacitinib', '477600-75-2', '3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile', 'Cp-690 free base', 'tofacitinibum', 'UNII-87LA6FU830', 'CHEBI:71200', '87LA6FU830', 'CP-690550 FREE BASE', 'CP-690,550 FREE BASE', '(+)-TOFACITINIB', '3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile', 'CP690,550', 'CP-690-550', 'HSDB 8311', 'DTXSID90197271', '3-((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo(2,3-d)pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile', '3-Piperidinamine, 1-(cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo(2,3-d)pyrimidin-4-yl-, (3R,4R)-', '3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile', 'JAK inhibitors: tofacitinib', 'DTXCID00119762', 'L04AA29', '1-PIPERIDINEPROPANENITRILE, 4-METHYL-3-(METHYL-7H-PYRROLO(2,3-D)PYRIMIDIN-4-YLAMINO)-beta-OXO-, (3R,4R)-', 'Tasocitinib', 'CP-690550', 'CP 690550', '1259404-17-5', 'rac-Tofacitinib', 'CP-690,550', 'Tofacitinib (CP-690550,Tasocitinib)', '3-((3R,4R)-rel-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile', 'Tofacitinib [USAN]', 'CP690550', 'racemic-tofacitinib', 'CHEMBL221959', 'racemic-Tasocitinib', '477600-75-2 (free base)', 'Tofacitinib (USAN)', '3-[(3R,4R)-4-methyl-3-[methyl({7H-pyrrolo[2,3-d]pyrimidin-4-yl})amino]piperidin-1-yl]-3-oxopropanenitrile', 'C16H20N6O', 'MFCD11035919', '3-[(3R*,4R*)-4-Methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile', '3-{(3R,4R)-4-Methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile', 'Tofacitinib [USAN:INN]', 'Tofacitinib?', '3eyg', '3fup', '3lxk', '4oti', 'MI1', 'Tofacitinib (Standard)', 'TOFACITINIB [MI]', 'TOFACITINIB [INN]', 'TOFACITINIB [VANDF]', 'TOFACITINIB [WHO-DD]', 'SCHEMBL322753', 'Tofacitinib (CP-690550)', 'GTPL5677', 'EX-A205', 'UJLAWZDWDVHWOW-YPMHNXCESA-N', 'BCPP000274', 'BDBM50193995', 'HY-40354R', 'NSC782351', 'NSC800953', 's2789', 'AKOS005145814', 'AKOS005258733', 'AC-8193', 'AT43433', 'BCP9000550', 'CCG-264998', 'CS-0050', 'DB08895', 'FT32555', 'GS-6106', 'NSC-782351', 'NSC-800953', 'SDCCGSBI-0654407.P002', 'NCGC00229511-02', 'NCGC00229511-04', 'NCGC00229511-10', 'NCGC00229511-25', 'NCGC00244463-01', 'Tofacitinib (CP-690550, Tasocitinib)', 'HY-40354', 'A7301', 'NS00069315', 'CP- 690 550', 'D09970', 'AB01565786_02', 'EN300-1718468', 'AR-270/43507983', 'Q3530324', 'BRD-K31283835-001-01-9', 'BRD-K31283835-048-04-4', '(3R,4R)-3-{4-Methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile', '(3R,4R)-4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-beta-oxo-1-piperidine propanenitrile', '1-PIPERIDINEPROPANENITRILE, 4-METHYL-3-(METHYL-7H-PYRROLO(2,3-D)PYRIMIDIN-4-YLAMINO)-.BETA.-OXO-, (3R,4R)-', '3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile citrate', '3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-1-piperidyl]-3-oxo-propanenitrile', '3-[(3R,4R)-4-Methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile;Tasocitinib', '3-{(3R,4R)-4-methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino]piperidin-1-yl}-3-oxo-propionitrile', '3-{(3R,4R)-4-Methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin4-yl)-amino]-piperidin-1-yl}-3-oxo-propionitrile', '3-{4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-1-piperidinyl}-3-oxopropanenitrile', 'REL-3-((3R,4R)-4-METHYL-3-(METHYL(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)AMINO)PIPERIDIN-1-YL)-3-OXOPROPANENITRILE', 'Tofacitinib;3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"C646 (chembl1797936)","PubChemCID":"1285940","SMILES":"CC1=NN(c2ccc(C(=O)O)cc2)C(=O)/C1=C\\c1ccc(-c2cc(C)c(C)cc2[N+](=O)[O-])o1","Synonyms":null,"Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Axitinib","PubChemCID":"6450551","SMILES":"CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)/C=C/C4=CC=CC=N4","Synonyms":"['Axitinib', '319460-85-0', 'AG-13736', 'axitinibum', 'C9LVQ0YUXG', 'UNII-C9LVQ0YUXG', 'NSC-757441', 'N-methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide', 'DTXSID3049049', 'CHEBI:66910', 'N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide', 'DTXCID8028975', 'NSC 757441', 'AXITINIB (MART.)', 'AXITINIB [MART.]', 'Benzamide, N-methyl-2-((3-((E)-2-(2-pyridinyl)ethenyl)-1H-indazol-6-yl)thio)-', 'N-METHYL-2-(3-((E)-2-PYRIDIN-2-YL-VINYL)-1H-INDAZOL-6-YLSULFANYL)-BENZAMIDE', 'Benzamide, N-methyl-2-((3-((1E)-2-(2-pyridinyl)ethenyl)-1H-indazo)-6-yl)thio)-', 'BENZAMIDE, N-METHYL-2-((3-((1E)-2-(2-PYRIDINYL)ETHENYL)-1H-INDAZOL-6-YL)THIO)-', 'N-METHYL-2((3-((1E0-2-(PYRIDIN-2-YL)ETHENYL)-1H-INAZOL-6-YLSUFANYL)BENZAMIDE', 'N-methyl-2-({3-[(1E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide', 'N-methyl-2-({3-[(E)-2-(pyridin-2-yl)vinyl]-1H-indazol-6-yl}sulfanyl)benzamide', 'N-methyl-2-((3-((E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide', 'N-methyl-2-((3-((E)-2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)sulfanyl)benzamide', 'L01XE17', 'N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethen-1-yl)-1H-indazol-6-yl)sulfanyl)benzamide', 'Inlyta', 'AG-013736', '(E)-N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide', 'AG 013736', 'MFCD09837898', 'NSC757441', 'N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide', 'NCGC00241108-01', 'S1005', 'Axitinib [USAN]', 'CAS-319460-85-0', 'AG013736', 'Axitinib [USAN:INN:JAN]', '4agc', '(E)-N-methyl-2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)benzamide', 'Axitinib (Standard)', 'Inlyta (TN)', '4ag8', 'Axitinib (JAN/USAN)', 'AXITINIB [INN]', 'AXITINIB [JAN]', 'AXITINIB [MI]', 'AXITINIB [VANDF]', 'AG-013736;Axitinib', 'AXITINIB [WHO-DD]', 'Axitinib,AG-013736', 'MLS006010164', 'SCHEMBL172918', 'AXITINIB [ORANGE BOOK]', 'GTPL5659', 'Axitinib, >=98% (HPLC)', 'CHEMBL1289926', 'N-methyl-2-[[3-[2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide', 'SCHEMBL22930506', 'BDBM25117', 'CHEBI:94568', 'EX-A337', 'BCPP000372', '1528729-60-3', 'BCP01371', 'Tox21_113597', 'HY-10065R', 'NSC799341', 'AKOS015902898', 'N-methyl-2-[[3-[(E)-2-(2-pyridyl)vinyl]-1H-indazol-6-yl]sulfanyl]benzamide', 'Tox21_113597_1', 'AC-1539', 'BCP9000345', 'CCG-264772', 'CS-0116', 'DB06626', 'FA18036', 'KS-1448', 'NSC-799341', 'SDCCGSBI-0646925.P002', 'N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide', 'NCGC00241108-04', 'NCGC00241108-06', 'HY-10065', 'SMR002530046', 'NS00005657', 'SW219464-1', 'D03218', 'AB01274739-01', 'AB01274739_02', 'EN300-26869010', 'SR-01000941566', 'Q4830631', 'SR-01000941566-1', 'BRD-K29905972-001-01-4', 'BRD-K29905972-001-02-2', 'BRD-K29905972-001-06-3', 'BRD-K29905972-001-08-9', 'BRD-K29905972-001-10-5', 'BRD-K29905972-001-11-3', 'BRD-K29905972-001-12-1', 'Z2216885372', 'N-Methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide', 'N-methyl-2-({3-[(E)-2-pyridin-2-ylethenyl]-2H-indazol-6-yl}sulfanyl)benzamide', 'N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide;AG 013736', 'N-methyl-2-[[3-[(E)-2-(2-pyridyl)vinyl]-2H-indazol-6-yl]sulfanyl]benzamide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Rolipram","PubChemCID":"5092","SMILES":"COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3","Synonyms":"['rolipram', '61413-54-5', '(R,S)-rolipram', 'Rolipramum [Latin]', '4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one', 'Rolipramum', '4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone', '4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one', 'ZK-62711', 'Rolipram [USAN:INN]', '4-(3-(Cyclopentyloxy)-4-methoxyphenyl)-2-pyrrolidinone', '4-(3-Cyclopentyloxy-4-methoxyphenyl)-2-pyrrolidone', 'EINECS 262-771-1', 'NSC-760125', 'BRN 1588548', 'DTXSID3044124', 'ZK 62 711', 'CHEBI:104872', 'K676NL63N7', 'ROLIPRAM [USAN]', 'ROLIPRAM [INN]', 'ROLIPRAM [JAN]', 'ROLIPRAM [MI]', 'ROLIPRAM [MART.]', 'ROLIPRAM [WHO-DD]', 'SB-95952', 'ZK-62771', '2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-', 'DTXCID1024124', 'Rolipramum (Latin)', 'NSC 760125', '2-Pyrrolidinone, 4-(3-(cyclopentyloxy)-4-methoxyphenyl)-', 'ROLIPRAM (MART.)', '4-(3-CYCLOPENTYLOXY-4-METHOXYPHENYL)PYRROLIDONE', '4-(3-cyclopentyloxy-4-methoxyphenyl)-2-pyrrolidinone', '4-[3-Cyclopentyloxy-4-methoxyphenyl]-2-pyrrolidinone', '(+-)-rolipram', 'Pyrrolidone, 4-(3-cyclopentyloxy-4-methoxyphenyl)-2-', '262-771-1', 'hjormjifdvbmob-uhfffaoysa-n', '(+/-)-Rolipram', 'ZK 62711', 'Adeo', '4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one', 'CHEMBL63', 'SB 95952', 'MLS000069691', 'SMR000058510', '(R,S)-Rolipram;SB 95952;ZK 62711', '4-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-pyrrolidinon', '4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolidin-2-one', '(R)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one', '(4R)-4-[3-(Cyclopentyloxy)-4 Methoxyphenyl)pyrrolidin-2-one', '(4S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-pyrrolidin-2-one', 'R-(-)-Rolipram', '[3H]rolipram', '[3H]-rolipram', 'SR-01000000162', 'UNII-K676NL63N7', 'Rolipram?', '(plusmn)-rolipram', 'NCGC00016899-01', 'CAS-61413-54-5', 'MFCD00270906', 'Rolipram (Standard)', 'ME-3167', 'Opera_ID_1749', 'Prestwick0_000924', 'Prestwick1_000924', 'Prestwick2_000924', 'Prestwick3_000924', 'UPCMLD-DP110', 'Lopac0_001072', 'SCHEMBL27930', 'BSPBio_000828', 'BSPBio_001356', 'KBioGR_000076', 'KBioSS_000076', 'Rolipram (JAN/USAN/INN)', 'MLS000758273', 'MLS000759531', 'MLS001146912', 'MLS001424084', 'MLS006010272', 'SPBio_003007', '(+)-Rolipram; (S)-Rolipram', 'BPBio1_000912', 'GTPL5260', 'GTPL5313', '4-[3-(cyclopentoxy)-4-methoxy-phenyl]pyrrolidin-2-one', 'UPCMLD-DP110:001', 'UPCMLD-DP110:002', 'BDBM14361', 'KBio2_000076', 'KBio2_002644', 'KBio2_005212', 'KBio3_000151', 'KBio3_000152', 'Bio2_000076', 'Bio2_000556', 'GLXC-06145', 'HMS1361D18', 'HMS1570J10', 'HMS1791D18', 'HMS1989D18', 'HMS2051N15', 'HMS2090J16', 'HMS2097J10', 'HMS2232F06', 'HMS3263G06', 'HMS3267A05', 'HMS3369J08', 'HMS3393N15', 'HMS3402D18', 'HMS3411F08', 'HMS3654P06', 'HMS3655J21', 'HMS3675F08', 'HMS3714J10', 'Pharmakon1600-01505683', 'BCP21910', 'BCP23388', 'Tox21_110672', 'Tox21_501072', 'EX-A10913', 'HB2896', 'HY-16900R', 'NSC760125', 'Rolipram, solid, >=98% (HPLC)', 's1430', 'Rolipram - CAS 61413-54-5', 'AKOS015959793', 'Tox21_110672_1', '( inverted exclamation markA)-Rolipram', 'CCG-100965', 'CCG-205149', 'CS-1754', 'DB01954', 'FR01270', 'KS-1400', 'LP01072', 'NC00215', 'SB12922', 'SDCCGSBI-0051042.P003', 'IDI1_033826', 'NCGC00015898-03', 'NCGC00015898-04', 'NCGC00015898-05', 'NCGC00015898-06', 'NCGC00015898-07', 'NCGC00015898-08', 'NCGC00015898-09', 'NCGC00015898-11', 'NCGC00015898-12', 'NCGC00015898-15', 'NCGC00015898-31', 'NCGC00089796-02', 'NCGC00089796-04', 'NCGC00089796-05', 'NCGC00089796-06', 'NCGC00089796-07', 'NCGC00089796-08', 'NCGC00261757-01', 'AC-32927', 'HY-16900', 'SBI-0051042.P002', 'DB-080675', 'AB00513966', 'EU-0101072', 'NS00034678', 'R0110', 'SW196583-4', 'D01783', 'R 6520', 'AB00384360-17', 'AB00384360_19', 'Q410285', '4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidinone', 'SR-01000000162-3', 'SR-01000000162-4', 'SR-01000000162-5', 'SR-01000000162-9', 'BRD-A34255068-001-04-8', 'BRD-A34255068-001-26-1', 'BRD-A34255068-001-32-9', 'BRD-A34255068-001-33-7', 'BRD-A34255068-001-34-5', 'SR-01000000162-12', '4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrolidin-2-one', '4-(3-cyclopentyloxy-4-methoxyphenyl)-pyrrolidin-2-one', '4-[4-Methoxy-3-(cyclopentyloxy)phenyl]-2-pyrrolidinone', '2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]- (9CI)']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Cabozantinib","PubChemCID":"25102847","SMILES":"COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F","Synonyms":"['Cabozantinib', '849217-68-1', 'XL 184', 'XL-184 free base', 'BMS 907351', 'CHEBI:72317', 'XL184 cpd', 'UNII-1C39JW444G', '1C39JW444G', 'BMS-907351 FREE BASE', 'DTXSID10233968', \"1,1-Cyclopropanedicarboxamide, N'-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-\", \"n-(4-((6,7-dimethoxy-4-quinolinyl)oxy)phenyl)-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide\", \"N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide\", \"N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide\", 'cabozantinibum', \"1,1-CYCLOPROPANEDICARBOXAMIDE, N'-(4-((6,7-DIMETHOXY-4-QUINOLINYL)OXY)PHENYL)-N-(4-FLUOROPHENYL)-\", \"1,1-CYCLOPROPANEDICARBOXAMIDE, N-(4-((6,7-DIMETHOXY-4-QUINOLINYL)OXY)PHENYL)-N'-(4-FLUOROPHENYL)-\", \"1,1-Cyclopropanedicarboxamide, N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-\", \"N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide\", 'DTXCID40156459', 'L01XE26', 'XL184', 'Cometriq', 'XL-184', 'BMS-907351', 'Cabozantinib (XL184, BMS-907351)', 'Cabozantinib [USAN]', \"N'-[4-[(6,7-DIMETHOXY-4-QUINOLINYL)OXY]PHENYL]-N-(4-FLUOROPHENYL)-1,1-CYCLOPROPANEDICARBOXAMIDE\", 'MFCD20926324', \"1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide\", 'Cabozantinib (USAN)', 'Cabometyx (TN)', 'Cometriq (TN)', 'Cabozantinib [USAN:INN]', 'Carbozantinib', \"Cabozantinib; N'-?[4-?[(6,?7-?Dimethoxy-?4-?quinolinyl)?oxy]?phenyl]?-?N-?(4-?fluorophenyl)?-1,?1-cyclopropanedicarbox?amide; N'-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide; BMS 907351; N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide\", 'Cabozantinib (Standard)', 'Cabozantinib (free base)', 'CABOZANTINIB [MI]', 'Cabozantinib (XL-184)', 'CABOZANTINIB [INN]', 'CABOZANTINIB [VANDF]', 'CABOZANTINIB [WHO-DD]', 'SCHEMBL360795', 'GTPL5887', 'Cabozantinib (BMS-907351)', 'CHEMBL2105717', 'EX-A075', 'BCPP000308', 'HMS3654G06', 'XL-184 free base (Cabozantinib)', 'BCP02591', '849217-68-1 (free base)', 'BDBM50021574', 'HY-13016R', 'NSC761068', 'NSC800066', 's1119', 'AKOS025142112', 'BCP9000470', 'CCG-264678', 'CS-0278', 'DB08875', 'FD59688', 'NSC-761068', 'NSC-800066', 'SB20062', 'SDCCGSBI-0646928.P001', 'XL-184 (Cabozantinib,BMS907351)', 'XL-184,Cabozantinib, BMS-907351', 'NCGC00263164-01', 'NCGC00263164-14', 'NCGC00263164-17', 'AC-25082', 'AS-16277', 'HY-13016', \"N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N'-(4-fluorophenyl)cyclopropane-1,1- dicarboxamide\", 'SY097158', 'XL-184 (Cabozantinib,BMS907351)?', 'DB-023624', 'NS00020240', 'SW218093-3', 'D10062', 'AB01565831_02', 'Q795057', 'SR-01000941569', 'SR-01000941569-1', 'BRD-K51544265-001-01-8', 'BRD-K51544265-001-04-2', 'BRD-K51544265-001-06-7', \"1,1-Cyclopropanedicarboxamide, N'-(4-((6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4- fluorophenyl)-\", 'cyclopropane-1,1-dicarboxylic acid [4-(6,7-dimethoxy-quinoline-4-yloxy)-phenyl]-amide(4-fluoro-phenyl)-amide', 'cyclopropane-1,1-dicarboxylic acid[4-(6,7-dimethoxy-quinoline-4-yloxy)-phenyl]-amide (4-fluoro-phenyl)-amide', \"N-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-N'-(4 fluorophenyl)cyclopropane-1,1-dicarboxamide\", \"N-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide\", \"N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide;Cabozantinib\", 'N-[4-[(6,7-Dimethoxyquinolin-4-yl)oxy]phenyl]-N inverted exclamation mark -(4-fluorophenyl)cyclopropane-1,1-dicarboxamide', \"N1-[4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl]-N1'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide\"]","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Torin","PubChemCID":"49836027","SMILES":"CCC(=O)N1CCN(CC1)C2=C(C=C(C=C2)N3C(=O)C=CC4=CN=C5C=CC(=CC5=C43)C6=CC7=CC=CC=C7N=C6)C(F)(F)F","Synonyms":null,"Type":"small molecule"},{"Action":"unknown","PerturbationName":"Verteporfin","PubChemCID":"168430535","SMILES":"CC1=C(C2=CC3=C(C(=C(N3)C=C4[C@]5([C@H](C(=CC=C5C(=CC6=C(C(=C(N6)C=C1N2)C=C)C)N4)C(=O)OC)C(=O)OC)C)C)CCC(=O)OC)CCC(=O)O.CC1=C(C2=CC3=C(C(=C(N3)C=C4[C@]5([C@H](C(=CC=C5C(=CC6=C(C(=C(N6)C=C1N2)C=C)C)N4)C(=O)OC)C(=O)OC)C)C)CCC(=O)O)CCC(=O)OC","Synonyms":null,"Type":"small molecule"},{"Action":"inhibit","PerturbationName":"AZ20","PubChemCID":"46244454","SMILES":"C[C@@H]1COCCN1C2=NC(=NC(=C2)C3(CC3)S(=O)(=O)C)C4=C5C=CNC5=CC=C4","Synonyms":"['(3R)-4-[2-(1H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)pyrimidin-4-yl]-3-methylmorpholine', 'DTXSID201025598', '(3R)-4-(2-(1H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)pyrimidin-4-yl)-3-methylmorpholine', 'DTXCID001509861', '808-402-5', 'AZ20', '1233339-22-4', 'AZ 20', '(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine', '1H-Indole, 4-[4-[(3R)-3-methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl]-', '4-[4-(1-methanesulfonylcyclopropyl)-6-[(3R)-3-methylmorpholin-4-yl]pyrimidin-2-yl]-1H-indole', 'CHEMBL2325697', '4-{4-[(3r)-3-methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1h-indole', 'VCD', 'compound 6 [PMID: 46244454]', 'GTPL8477', 'SCHEMBL2511931', 'CHEBI:124915', 'SCGCBAAYLFTIJU-CQSZACIVSA-N', 'GLXC-05810', 'EX-A1801', 'IZB33922', 'BDBM50427326', 's7050', 'AKOS024458534', 'CCG-268793', 'CS-1483', 'AZ20, >=98% (HPLC)', 'NCGC00386311-06', '4-[4-[(3R)-3-Methyl-4-morpholinyl]-6-[1-(methylsulfonyl)cyclopropyl]-2-pyrimidinyl]-1H-indole', 'AC-32952', 'AS-16518', 'HY-15557', 'SW219703-1', 'BRD-K42436189-001-01-2', 'BRD-K42436189-001-03-8', 'Q27074665', '(3R)-4-[2-(1H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)pyrimidin-4-yl]-3-methyl-morpholine']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"GO6983","PubChemCID":"3499","SMILES":"CN(C)CCCN1C=C(C2=C1C=CC(=C2)OC)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54","Synonyms":"['go 6983', '133053-19-7', 'Go6983', '3-[1-[3-(Dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione', 'Go-6983', 'Goe 6983', '3-(1-(3-(dimethylamino)propyl)-5-methoxy-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione', 'Go-6893', '1H-Pyrrole-2,5-dione, 3-[1-[3-(dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-', 'CHEMBL261491', 'Go 6983;Goe 6983', '3-{1-[3-(dimethylamino)propyl]-5-methoxy-1H-indol-3-yl}-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione', '2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1h-indol-3-yl)maleimide', 'Goe-6983', 'MFCD04040031', 'Gouml 6983', 'G ouml 6983', '3-[1-[3-(dimethylamino)propyl]-5-methoxyindol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione', 'G? 6983', 'MLS006011225', 'GTPL5192', 'SCHEMBL1680253', 'CHEBI:91455', 'DTXSID60274402', 'GLXC-05234', 'HMS3229E15', 'HMS3650B11', 'HMS3651D10', 'BCP06669', 'EX-A1221', 'G 6983;Goe 6983', 'BDBM50616055', 'Go 6983?', 'HB0303', 's2911', 'GO 6983; Goe 6983', 'AKOS024457028', 'CCG-206756', 'SB19440', 'SDCCGSBI-0086679.P003', 'NCGC00163505-01', 'NCGC00163505-03', 'AC-32991', 'AS-74619', 'DA-63858', 'Go6983(96%)', 'HY-13689', 'SMR004702986', 'SW219419-1', 'SR-01000946321', 'Go 6983 - CAS 133053-19-7', 'SR-01000946321-1', 'BRD-K36984403-001-02-7', 'BRD-K36984403-001-03-5', 'Q27077833', 'G?? 6983, >=97%', '3-[1-[3-(dimethylamino)propyl]-5-methoxy-indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione', '3-{1-[3-(DIMETHYLAMINO)PROPYL]-5-METHOXYINDOL-3-YL}-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Geldanamycin","PubChemCID":"5288382","SMILES":"C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\\C=C(\\C(=O)NC2=CC(=O)C(=C(C1)C2=O)OC)/C)OC)OC(=O)N)\\C)C)O)OC","Synonyms":"['geldanamycin', '30562-34-6', 'geldanomycin', 'UNII-Z3K3VJ16KU', 'CHEBI:5292', 'Z3K3VJ16KU', 'NSC-122750', 'GELDANAMYCIN [MI]', 'U-29135', 'BRN 1633093', 'DTXSID7042691', 'U 29135', '[(3R,5S,6R,7S,8E,10S,11S,12Z,14E)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate', 'Antibiotic U 29135', '[(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate', 'Antibiotic (U-29,135)', 'NSC212518', '((3R,5S,6R,7S,8E,10S,11S,12Z,14E)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo(16.3.1)docosa-1(21),8,12,14,18-pentaen-10-yl) carbamate', '((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo(16.3.1)docosa-1(21),4,6,10,18-pentaen-9-yl) carbamate', 'DTXCID5022691', '805-356-8', 'MFCD00274570', 'Geldanamycin from Streptomyces hygroscopicus', 'GDM', '(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate', 'NSC 122750', '1yet', 'Geldanamycin (9CI)', 'SCHEMBL4154', 'BSPBio_001073', 'GTPL9829', 'CHEBI:91381', 'HMS1362E15', 'HMS1792E15', 'HMS1990E15', 'HMS3403E15', 'BDBM50008059', 'EI-280', 'AKOS024456552', 'AG23651', 'CCG-208040', 'DB02424', 'IDI1_002122', 'NCGC00163449-01', 'NCGC00163449-02', '2-Azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9,13-dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-, 9-carbamate (8CI)', 'G0334', 'NS00011696', 'SR-05000002266', 'A1-50253', 'SR-05000002266-3', 'BRD-K11528507-001-01-8', 'Z2568648438', 'Geldanamycin, Streptomyces hygroscopicus - CAS 30562-34-6', 'Geldanamycin from Streptomyces hygroscopicus, >=98% (HPLC), powder', '[(3S,5S,6R,7S,8E,10R,11S,12Z,14E)-6-Hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-8,12,14,18,21-pentaen-10-yl] carbamate', '2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9-[(aminocarbonyl)oxy]-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-, (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-', '2-Azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9-[(aminocarbonyl)oxy]-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-, [8S-(4E,6Z,8R*,9R*,10E,12R*,13S*,14R*,16S*)]-', '9,13-Dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione 9-carbamate ;(+)-Geldanamycin;NSC 122750', 'GMY']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"JNJ","PubChemCID":"16720561","SMILES":"CN(C)CC1=NC=CN1C2=CC(=C(C=C2)C3=C(C4=C(C=C3)C(=NN4C5=CC6=C(C=C5)ON=C6N)C(=O)N)F)F","Synonyms":"['CHEMBL398870', '1-(3-Amino-1,2-Benzisoxazol-5-Yl)-6-(4-{2-[(Dimethylamino)methyl]-1h-Imidazol-1-Yl}-2-Fluorophenyl)-7-Fluoro-1h-Indazole-3-Carboxamide', 'SCHEMBL5101047', 'BDBM50231272', 'Q27461743', '1-(3-aminobenzo[d]isoxazol-5-yl)-6-[4-(2-dimethylaminomethylimidazol-1-yl)-2-fluorophenyl]-7-fluoro-1H-indazole-3-carboxylicacid amide', 'JNJ']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Endothelin","PubChemCID":"44284481","SMILES":"CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC3=CNC=N3)NC(=O)[C@@H]4CSSC[C@H](C(=O)N[C@@H](C(=O)N[C@H]5CSSC[C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N4)CC6=CC=CC=C6)CC7=CC=C(C=C7)O)C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](NC5=O)CO)CO)CC(C)C)CCSC)CC(=O)O)CCCCN)CCC(=O)O)CO)N","Synonyms":"['Endothelin', 'ENDOTHELIN [MI]', 'DTXSID5037654', 'Endothelium-derived contractile factor 2', '116243-73-3', 'Et 1', 'Endothelin 1', 'Endothelin 1 (Rana ridibunda)', 'Endothelin (porcine)', 'BDBM50289653']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"LY2835219","PubChemCID":"46220502","SMILES":"CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F","Synonyms":"['Abemaciclib', '1231929-97-7', 'Verzenio', 'UNII-60UAB198HK', 'Verzenios', '60UAB198HK', 'LY 2835219', 'HY-16297A', 'CS-1230', 'LY 2835210', '2-Pyrimidinamine, N-(5-((4-ethyl-1-piperazinyl)methyl)-2-pyridinyl)-5-fluoro-4-(4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl)', '5-(4-ethylpiperazin-1-ylmethyl)pyridin-2-yl)-(5-fluoro-4-(7-fluoro-3-isopropyl-2-methyl-3H-benzimidazol-5-yl)pyrimidin-2-yl)amine', '5-(4-ethylpiperazin-1-ylmethyl)pyridin-2-yl)-(5-fluoro-4-(7-fluoro-3-isopropyl-2-methyl-3H-benzoimidazol-5-yl)pyrimidin-2-yl)amine', 'abemaciclibum', 'L01XE50', 'N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl)pyrimidin-2-amine', 'LY2835219', 'LY2835219 free base', 'LY-2835219', 'N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine', '2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-', 'N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine', 'LY2835210', 'N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-(7-fluoro-3-isopropyl-2-methyl-1,3-benzodiazol-5-yl)pyrimidin-2-amine', 'N-{5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]pyrimidin-2-amine', 'LY2835219 (free base)', 'Abemaciclib [USAN:INN]', 'rimidin-2-amine', 'C27H32F2N8', 'Verzenio (TN)', '6ZV', 'N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]py rimidin-2-amine', 'MFCD22665744', 'Abemaciclib (Standard)', 'ABEMACICLIB [MI]', 'ABEMACICLIB [INN]', 'ABEMACICLIB [JAN]', 'ABEMACICLIB [USAN]', 'ABEMACICLIB [WHO-DD]', 'Abemaciclib (JAN/USAN/INN)', 'GTPL7382', 'SCHEMBL2487229', 'CHEMBL3301610', 'ABEMACICLIB [ORANGE BOOK]', 'DTXSID20673119', 'EX-A521', 'LY 2835219 (free base)', 'CHEBI:233362', 'UZWDCWONPYILKI-UHFFFAOYSA-N', 'HMS3673I05', 'HY-16297AR', 'BCP13079', 'EX-A1588', 'BDBM50110183', 'NSC768073', 'NSC783671', 's5716', '1231929-97-7, Verzenio,', 'AKOS025404907', 'LY2835219 free base (Abemaciclib)', 'CCG-269750', 'DB12001', 'NSC-768073', 'NSC-783671', 'SB16476', 'LY2835219 free base (Abemaciclib)?', 'NCGC00351599-02', 'NCGC00351599-06', 'AC-30666', 'AS-10230', 'DA-33422', 'FE103812', 'LY2835219 Ms salt, Abemaciclib Ms salt', 'LY-2835210', 'NS00072970', 'D10688', 'EN300-7406007', 'BRD-K33622447-066-01-9', 'Q23901483', '[5-(4-ethyl-piperazin-1-ylmethyl)-pyridin-2-yl]-[5-fluoro-4-(7-fluoro-3-isopropyl-2-methyl-3H-benzoimidazol-5-yl)-pyrimidin-2-yl]-amine', 'Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine', 'N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine', 'N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-1,3-benzodiazol-6-yl]pyrimidin-2-amine', 'N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]py']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Jq1","PubChemCID":"46907787","SMILES":"CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C","Synonyms":"['1268524-70-4', '(+)-JQ1', '(+)-JQ-1', 'JQ1 compound', 'JQ1', '(S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate', 'JQ-1', '(S)-JQ1', '1MRH0IMX0W', '6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl-, 1,1-dimethylethyl ester, (6S)-', '(S)-(+)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate', '(S)-(+)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate', 'CHEMBL1957266', '6H-Thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl-, 1,1-dimethylethyl ester, (6S)-', 'tert-butyl (S)-2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate', 'tert-Butyl 2-((6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate', 'tert-butyl 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate', '(S)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno-[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate', 'UNII-1MRH0IMX0W', '3mxf', '4flp', '4qzs', 'tert-butyl 2-((6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate', 'MLS006011158', 'SCHEMBL881227', 'GTPL7511', '(+)-SGCBD01', 'CHEBI:95080', 'DTXSID20155309', 'EX-A457', 'CHEBI:137113', 'DNVXATUJJDPFDM-KRWDZBQOSA-N', 'BDBM50365262', 'HB1448', 'NSC760183', 'NSC764043', 's7110', 'AKOS016344680', '(+)JQ-1', 'CCG-269306', 'CS-0581', 'FC43273', 'JQ1 (+)', 'JQ1-(+)', 'NSC-760183', 'NSC-764043', 'NCGC00250412-01', 'NCGC00250412-09', 'NCGC00250412-15', 'NCGC00250412-21', '(+)-JQ 1', '(+)-JQ1?', '(S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diaz', 'AC-32617', 'AS-16352', 'BP-21590', 'DA-68975', 'HY-13030', 'SMR004702930', '(+)-JQ1, >=98% (HPLC)', 'EN300-7404173', 'Q3156953', 'BRD-K54606188-001-13-1', 'Z2235802082', '[(S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-1-thia-5,7,8,9a-tetraaza-cyclopenta[e]azulen-6-yl]-acetic acid tert-butyl ester;(S)-(', 'tert-butyl [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetate', 'tert-butyl 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0,2,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate', 'tert-butyl[(S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetate']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Ulixertinib","PubChemCID":"11719003","SMILES":"CC(C)NC1=NC=C(C(=C1)C2=CNC(=C2)C(=O)N[C@H](CO)C3=CC(=CC=C3)Cl)Cl","Synonyms":"['Ulixertinib', 'VRT752271', 'Ulixertinib [INN]', 'BVD-523', 'UNII-16ZDH50O1U', 'BVD-ERK', '16ZDH50O1U', 'Ulixertinib (INN)', 'VRT-752271', 'ULIXERTINIB [WHO-DD]', '1H-Pyrrole-2-carboxamide, 4-(5-chloro-2-((1-methylethyl)amino)-4-pyridinyl)-N-((1S)-1-(3-chlorophenyl)-2-hydroxyethyl)-', 'N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-4-[5-chloro-2-(propan-2-ylamino)pyridin-4-yl]-1H-pyrrole-2-carboxamide', '4-{5-chloro-2-[(propan-2-yl)amino]pyridin-4-yl}-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]-1H-pyrrole-2-carboxamide', 'ulixertinibum', '4-(5-chloro-2-((propan-2-yl)amino)pyridin-4-yl)-N-((1S)-1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide', 'N-((1S)-1-(3-chlorophenyl)-2-hydroxyethyl)-4-(5-chloro-2-(propan-2-ylamino)pyridin-4-yl)-1H-pyrrole-2-carboxamide', '869886-67-9', 'Ulixertinib (BVD-523)', 'Ulixertinib (BVD-523, VRT752271)', '(S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide', 'CHEMBL3590106', '869886-67-9 (free base)', 'VRT752271 HCl', '(S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide.', '4-[5-chloranyl-2-(propan-2-ylamino)pyridin-4-yl]-~{N}-[(1~{S})-1-(3-chlorophenyl)-2-oxidanyl-ethyl]-1~{H}-pyrrole-2-carboxamide', 'BVD523 HCl', 'BVD-523 HCl', 'GTPL9210', 'SCHEMBL14211742', 'BCP04232', 'EX-A1332', 'BDBM50094465', 'NSC797771', 'NSC800959', 's7854', 'AKOS025396467', 'CCG-269049', 'DB13930', 'NSC-797771', 'NSC-800959', 'NCGC00378692-02', 'NCGC00378692-05', 'NCGC00378692-07', 'AC-33165', 'AS-56114', 'FU157994', 'HY-15816', 'BCP0726000085', 'NS00072098', 'D11038', 'G60969', 'BRD-K28965160-001-01-1', 'Q27089081', 'Z2756516977', '4-[5-Chloro-2-[(1-methylethyl)amino]-4-pyridinyl]-N-[(1S)-1-(3-chlorophenyl)-2-hydroxyethyl]1H-pyrrole-2-carboxamide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"AZD5363","PubChemCID":"25227436","SMILES":"C1CN(CCC1(C(=O)N[C@@H](CCO)C2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4","Synonyms":"['capivasertib', '1143532-39-1', 'AZD5363', 'AZD-5363', 'AZD 5363', 'Truqap', '4-Amino-N-[(1s)-1-(4-Chlorophenyl)-3-Hydroxypropyl]-1-(7h-Pyrrolo[2,3-D]pyrimidin-4-Yl)piperidine-4-Carboxamide', '4-Piperidinecarboxamide, 4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-', 'WFR23M21IE', 'cc-638', 'CAPIVASERTIB [INN]', 'CAPIVASERTIB [JAN]', 'CAPIVASERTIB [USAN]', 'CAPIVASERTIB [WHO-DD]', 'AZC5363', 'DTXSID40150710', '4-Amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxypropyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4-piperidinecarboxamide', '4-amino-N-(1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)piperidine-4-carboxamide', '4-AMINO-N-[(1S)-1-(4-CHLOROPHENYL)-3-HYDROXYPROPYL]-1-{7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL}PIPERIDINE-4-CARBOXAMIDE', '4-PIPERIDINECARBOXAMIDE, 4-AMINO-N-((1S)-1-(4-CHLOROPHENYL)-3-HYDROXYPROPYL)-1-(7H-PYRROLO(2,3-D)PYRIMIDIN-4-YL)-', 'capivasertibum', '4-amino-N-((1S)-1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)-4-piperidinecarboxamide', '4-Amino-N-((1S)-1-(4-chlorophenyl)-3-hydroxypropyl)-1-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)piperidine-4-carboxamide', 'DTXCID4073201', '4-AMINO-N-((1S)-1-(4-CHLOROPHENYL)-3-HYDROXYPROPYL)-1-(1H-PYRROLO(2,3-D)PYRIMIDIN-4-YL)PIPERIDINE-4-CARBOXAMIDE', '682-662-6', '(S)-4-AMINO-N-(1-(4-CHLOROPHENYL)-3-HYDROXYPROPYL)-1-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PIPERIDINE-4-CARBOXAMIDE', 'UNII-WFR23M21IE', 'CHEMBL2325741', 'Capivasertib?', 'MFCD22628785', 'Truqap (TN)', 'Capivasertib (JAN/USAN)', 'Capivasertib (AZD5363)', 'MLS006011179', 'SCHEMBL390243', 'GTPL7709', 'EX-A285', 'CHEBI:229222', 'JDUBGYFRJFOXQC-KRWDZBQOSA-N', 'US10654855, Example 9', 'BDBM443385', 'AZD5363?', 'NSC764039', 'NSC782347', 'NSC799347', 's8019', 'AKOS027323693', 'BCP9000365', 'CCG-268989', 'CS-1284', 'DB12218', 'FA29493', 'NSC-764039', 'NSC-782347', 'NSC-799347', 'NCGC00345795-01', 'NCGC00345795-03', 'NCGC00345795-04', 'NCGC00345795-08', 'AC-32685', 'HY-15431', 'SMR004702948', 'BCP0726000111', 'DB-290280', 'NS00072563', 'SW220158-1', 'D11371', 'BRD-K99023089-001-03-7', 'Q27074756', '0XZ', '4-AMINO-N-((1S)-1-(4-CHLOROPHENYL)-3-HYDROXYPROPYL)-1- (1H-PYRROLO(2,3-D)PYRIMIDIN-4-YL)PIPERIDINE-4-CARBOXAMIDE', '4-amino-N-[(1S)-1-(4-chlorophenyl)-3-hydroxy-propyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide', 'ALTERNATIVE ROUTE 1: (S)-4-AMINO-N-(1-(4-CHLOROPHENYL)-3-HYDROXYPROPYL)-1-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PIPERIDINE-4-CARBOXAMIDE']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Pazopanib","PubChemCID":"10113978","SMILES":"CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N","Synonyms":"['Pazopanib', '444731-52-6', 'GW786034', '790713-33-6', '5-((4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide', 'pazopanibum', 'GW 786034', 'UNII-7RN5DR86CK', '7RN5DR86CK', 'NSC-752782', 'DTXSID8048733', 'GW 78603', 'CHEBI:71219', 'indazolylpyrimidine 13', 'HSDB 8210', 'DTXCID1028659', 'NSC 752782', '5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide', 'Benzenesulfonamide, 5-((4-((2,3-dimethyl-2H-indazol-6-yl)methylamino)-2-pyrimidinyl)amino)-2-methyl-', '5-({4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide', 'GW7 86034', 'Votrient', 'MFCD11616589', '5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzene-1-sulfonamide', 'GW-786034', 'NCGC00188865-01', '5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide', '5-[[4-[(2,3-dimethyl-2h-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide', 'Pazopanib [INN]', 'CAS-444731-52-6', 'Pazopanib [INN:BAN]', '5-[4-[(2,3-Dimethyl-2H-indazol-6-yl)-methyl-amino]-pyrimidin-2-ylamino]-2-methyl-benzenesulfonamide', 'Pazopanib?', 'Benzenesulfonamide, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-; 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide; 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide; GW 786034; Pazopanib; Votrient', 'Pazopanib (Standard)', 'GW 786034B', 'Pazopanib (free base)', 'Kinome_3790', 'GW780604', 'PAZOPANIB [MI]', 'GW-780604', '5-[[4-[(2,3-dimethyl-2h-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide', 'PAZOPANIB [VANDF]', 'PAZOPANIB [WHO-DD]', 'PAZOPANIB [EMA EPAR]', '5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide', 'SCHEMBL588608', 'Pazopanib - Bio-X trade mark', 'CHEMBL477772', 'GTPL5698', 'JMC514632 Compound 13', 'BDBM26474', 'cid_10113978', 'CUIHSIWYWATEQL-UHFFFAOYSA-N', 'BCPP000129', 'HMS3244C21', 'HMS3244C22', 'HMS3244D21', 'HMS3656L14', 'HMS3745G05', 'BCP01839', 'EX-A1241', 'Tox21_113174', 'HY-10208R', 'NSC752782', 'NSC800839', 's3012', 'AKOS005145819', 'Tox21_113174_1', 'AC-8522', 'BCP9001053', 'CCG-265010', 'CS-0269', 'DB06589', 'FD26771', 'NSC-800839', 'SB17290', 'SDCCGSBI-0647656.P002', 'NCGC00188865-02', 'NCGC00188865-03', 'NCGC00188865-10', 'AS-11066', 'BD164238', 'HY-10208', 'NS00070516', 'SW218082-3', 'EN300-57325', 'P-6706', 'SBI-0647656.0001', 'AB01273967-01', 'AB01273967-02', 'AB01273967_05', 'AB01273967_06', 'AR-270/43507999', 'Q7157043', 'BRD-K74514084-001-03-9', 'BRD-K74514084-003-02-7', 'BRD-K74514084-003-09-2', 'Z1541638525', '5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]-2-pyrimidinyl}amino)-2-methylbenzenesulfonamide', '5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]-pyrimidin-2-yl]amino]-2-methyl-benzenesulfonamide', 'Votrient;5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Ci","PubChemCID":"18218197","SMILES":"CCC(C)C(C(=O)O)NC(=O)C(CS)N","Synonyms":"['Cysteinyl-Isoleucine', 'Cys-Ile', 'L-Cysteinyl-L-Isoleucine', 'cysteylisoleucine', 'CI dipeptide', 'C-I Dipeptide', 'Cysteinylisoleucine', 'Cysteine Isoleucine dipeptide', 'Cysteine-Isoleucine dipeptide', 'CHEBI:192307', 'VBIIZCXWOZDIHS-UHFFFAOYSA-N', '2-[(2-amino-3-sulanylpropanoyl)amino]-3-methylpentanoic acid', 'CI']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Belinostat","PubChemCID":"6918638","SMILES":"C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO","Synonyms":"['Belinostat', '866323-14-0', 'Beleodaq', 'PXD-101', 'E-Belinostat', 'NSC726630', 'PX-105684', 'UNII-F4H96P17NZ', 'F4H96P17NZ', 'CHEBI:61076', '2-Propenamide, N-hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-, (2E)-', 'PXD 101', '(2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide', 'DTXSID60194378', 'N-hydroxy-3-(3-(phenylsulfamoyl)phenyl)prop-2-enamide', '(2E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]acrylamide', '2-Propenamide, N-hydroxy-3-(3-((phenylamino)sulfonyl)phenyl)-, (2E)-', '2-Propenamide, N-hydroxy-3-(3-((phenylamino)sulfonyl)phenyl)-', '(2E)-N-HYDROXY-3-(3-(PHENYLSULFAMOYL)PHENYL)PROP-2-ENAMIDE', 'N-HYDROXY-3-(3-((PHENYLAMINO)SULFONYL)PHENYL)-2-PROPENAMIDE', '(2E)-N-hydroxy-3-(3-(phenylsulfamoyl)phenyl)acrylamide', 'N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide', 'belinostatum', 'DTXCID70116869', 'L01XX49', '414864-00-9', 'PXD101', 'Belinostat (PXD101)', '(E)-N-hydroxy-3-(3-(N-phenylsulfamoyl)phenyl)acrylamide', 'N-HYDROXY-3-(3-PHENYLSULFAMOYLPHENYL)ACRYLAMIDE', 'N-Hydroxy-3-(3-(N-phenylsulfamoyl)phenyl)acrylamide', '(E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide', 'NSC-726630', '(E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide.', 'Belinostat [USAN]', 'Belinostat [USAN:INN]', 'PXD101;PX105684', 'Beleodaq (TN)', 'MFCD08064035', 'BELINOSTAT [MI]', 'BELINOSTAT [INN]', 'Belinostat (USAN/INN)', 'Belinostat (PXD101)?', 'BELINOSTAT [VANDF]', 'N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]-2-propenamide', 'BELINOSTAT [WHO-DD]', 'N-Hydroxy-3-(3-phenylsulphamoylphenyl)acrylamide', 'MLS006011091', 'CHEMBL408513', 'GTPL7496', 'BELINOSTAT [ORANGE BOOK]', 'Belinostat(Random Configuration)', 'BDBM25150', 'CHEBI:94531', 'EX-A180', 'NCNRHFGMJRPRSK-MDZDMXLPSA-N', '(E)-3-[3-(phenylsulfamoyl)phenyl]prop-2-enehydroxamic acid', 'BCPP000351', 'BCP01741', 'PRA86400', 'Belinostat,PXD101, PX105684', 'NSC758774', 's1085', 'AKOS025401741', 'BCP9000386', 'CCG-208758', 'DB05015', 'FB76300', 'NSC-758774', 'NCGC00263155-02', 'NCGC00263155-05', 'NCGC00263155-09', 'AC-25046', 'AC-35365', 'AS-17068', 'BP-40065', 'SMR004702879', 'B5888', 'NS00069313', 'SW219445-1', 'D08870', 'EN300-7361191', 'Q4882925', 'BRD-K17743125-001-01-9', 'BRD-K17743125-001-08-4', '(E)-N-Hydroxy-3-(3-phenylsulfamoyl-phenyl)-acrylamide', 'PXD 101;PX 105684;(2E)-N-Hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide', '5OG']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"CX4945","PubChemCID":"24748573","SMILES":"C1=CC(=CC(=C1)Cl)NC2=NC3=C(C=CC(=C3)C(=O)O)C4=C2C=CN=C4","Synonyms":"['Silmitasertib', '1009820-21-6', '5-((3-Chlorophenyl)amino)benzo[c][2,6]naphthyridine-8-carboxylic acid', 'CX 4945', 'Cx-4945 free acid', 'UNII-C6RWP0N0L2', 'C6RWP0N0L2', '5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid', '5-[(3-chlorophenyl)amino]-Benzo[c]-2,6-naphthyridine-8-carboxylic acid', 'Benzo[c]-2,6-naphthyridine-8-carboxylic acid, 5-[(3-chlorophenyl)amino]-', 'DTXSID40143602', '5-[(3-Chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-Carboxylic Acid', '5-(3-chlorophenylamino)benzo(c)(2,6)naphthyridine-8-carboxylic acid', '5-((3-CHLOROPHENYL)AMINO)BENZO(C)(2,6)NAPHTHYRIDINE-8-CARBOXYLIC ACID', 'BENZO(C)-2,6-NAPHTHYRIDINE-8-CARBOXYLIC ACID, 5-((3-CHLOROPHENYL)AMINO)-', 'silmitasertibum', '5-((3-chlorophenyl)amino)-benzo(c)-2,6-naphthyridine-8-carboxylic Acid', 'DTXCID9066093', 'CX-4945', 'CX-4945 (Silmitasertib)', 'CX4945', 'Silmitasertib [INN]', 'CX4945 (Silmitasertib)', 'Silmitasertib (CX-4945)', 'MFCD13184796', '5-[(3-chlorophenyl)amino]benzo[c]2,6-naphthyridine-8-carboxylic acid', 'CHEMBL1230165', '5-((3-Chlorophenyl)amino)benzo-[c][2,6]naphthyridine-8-carboxylic acid', '5-(3-chloroanilino)benzo[c][2,6]naphthyridine-8-carboxylic acid', 'C19H12ClN3O2', '3NG', '5-[(3-Chlorophenyl)amino]benzo[c]-2,6-naphthyridine-8-carboxylic acid', 'Silmitasertib; CX 4945', 'CX-4945 (Silmitaserib)', 'CX 4945 (Silmitasertib)', 'SCHEMBL629082', 'SILMITASERTIB [WHO-DD]', 'GTPL8126', 'EX-A070', 'CHEBI:232159', 'CHEBI:232617', 'GLXC-04060', 'HMS3244M13', 'HMS3244M14', 'HMS3244N13', 'HMS3655F16', 'HMS3746E13', 'BCP02399', 'BDBM50335638', 'NSC761193', 'NSC800885', 's2248', 'AKOS005266722', 'BCP9000560', 'CCG-264955', 'CS-0563', 'DB15408', 'EX-8673', 'FC30749', 'NSC-761193', 'NSC-800885', 'SB17201', 'SDCCGSBI-0654415.P001', 'NCGC00263192-01', 'NCGC00263192-02', 'NCGC00263192-09', 'NCGC00263192-13', 'AC-28426', 'AS-16253', 'HY-50855', 'SY069677', 'DB-016103', 'SW218157-2', 'EN300-6482034', 'BRD-K81458380-001-04-9', 'CX-4945,CAS:1009820-21-6', 'Q27076934', '5-[(3-chlorophenyl)amino]pyrido[4,3-c]quinoline-8-carboxylic acid', '5-[(3-Chlorophenyl)amino]-Benzo[c]-2,6-naphthyridine-8-carboxylic acid;silmitasertib']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Bix","PubChemCID":"16656807","SMILES":"C1=CC(=C(C=C1C(=O)CSC#N)O)O","Synonyms":"['2-(Cyanosulfanyl)-1-(3,4-dihydroxyphenyl)ethan-1-one', '808-327-8', '101714-41-4', 'BiP inducer X', '2-(3,4-dihydroxyphenyl)-2-oxoethyl thiocyanate', 'BIX', 'Thiocyanic acid, 2-(3,4-dihydroxyphenyl)-2-oxoethyl ester', '2-(CYANOSULFANYL)-1-(3,4-DIHYDROXYPHENYL)ETHANONE', '1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone', '[2-(3,4-dihydroxyphenyl)-2-oxoethyl] thiocyanate', 'SCHEMBL16428338', 'CHEBI:85310', 'DTXSID60586532', 'BEA71441', 'BIX, >=98% (HPLC)', 'STL417030', 'AKOS025118611', 'NCGC00387485-03', 'AS-79949', 'DA-51170', 'HY-110188', 'CS-0033052', 'EN300-209059', 'F76060', '1-(3,4-dihydroxyphenyl)-2-thiocyanato-ethanone', 'immunoglobulin heavy-chain binding protein inducer X', 'Q27158473']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Crizotinib","PubChemCID":"11626560","SMILES":"C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N","Synonyms":"['Crizotinib', '877399-52-5', '(R)-crizotinib', 'PF-2341066', 'PF 2341066', '(R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine', 'crizotinibum', 'UNII-53AH36668S', 'CHEBI:64310', 'PF2341066', '53AH36668S', 'NSC-756645', 'DTXSID701009329', 'NSC 756645', '3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine', 'CRIZOTINIB (MART.)', 'CRIZOTINIB [MART.]', '2-Pyridinamine, 3-((1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(4-piperidinyl)-1H-pyrazol-4-yl)-', '2-PYRIDINAMINE, 3-[(1R)-1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY]-5-[1-(4-PIPERIDINYL)-1H-PYRAZOL-4-YL]-', '3-((1R)-1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY)-5-(1-(PIPERIDIN-4-YL)-1H-PYRAZOL-4-YL)PYRIDIN-2-AMINE', 'L01XE16', 'DTXCID601436157', 'MET Tyrosine Kinase Inhibitor PF-02341066', '1066', 'PF-02341066', 'Xalkori', 'Crizotinib (PF-02341066)', '3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine', '3-[(1R)-1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY]-5-[1-(4-PIPERIDINYL)-1H-PYRAZOL-4-YL]PYRIDIN-2-AMINE', 'CHEMBL601719', 'Crizotinib (PF-2341066)', '877399-52-5 (free base)', '3-[(1r)-1-(2,6-Dichloro-3-Fluorophenyl)ethoxy]-5-(1-Piperidin-4-Yl-1h-Pyrazol-4-Yl)pyridin-2-Amine', 'PF 02341066', '3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine', 'Xalkori (TN)', 'Crizotinib [USAN]', 'Crizotinib [USAN:INN]', 'VGH', 'MFCD12407409', 'Crizotinib (Standard)', 'CRIZOTINIB [MI]', 'CRIZOTINIB [INN]', 'CRIZOTINIB [JAN]', 'CRIZOTINIB [VANDF]', 'CRIZOTINIB [WHO-DD]', 'SCHEMBL93829', 'PF-2341066,Crizotinib', 'Crizotinib (JAN/USAN/INN)', 'Crizotinib - Bio-X trade mark', 'GTPL4903', 'CRIZOTINIB [ORANGE BOOK]', 'Crizotinib, >=98% (HPLC)', 'EX-A096', 'Crizotinib (PF-2341066)?', 'KTEIFNKAUNYNJU-GFCCVEGCSA-N', 'BCPP000116', 'GLXC-04599', 'PF 2341066;(R)-3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine', 'BDBM50306682', 'HY-50878R', 'NSC749005', 'NSC749769', 'NSC800080', 'AKOS015901233', 'AKOS015995207', 'CCG-264803', 'DB08865', 'FD20585', 'GS-6178', 'NSC-749005', 'NSC-749769', 'NSC-800080', 'SDCCGSBI-0647655.P002', 'NCGC00250400-01', 'NCGC00250400-02', 'NCGC00250400-09', 'NCGC00250400-12', 'BC164334', 'HY-50878', 'NS00072165', 'SW202555-3', 'D09731', 'Q5186964', 'BRD-K78431006-001-01-1', 'BRD-K78431006-001-03-7', 'BRD-K78431006-001-10-2', 'BRD-K78431006-001-11-0', '877399-52-5, 877399-53-6 (acetate)', 'Z2065417924', '3-(2,6-dichloro-3-fluorobenzyloxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine', '(R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-am ine', '(R)-3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine', '3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyra zol-4-yl]-2-pyridinamine', '3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine;(R)-3-[1-(2,6-Dichloro-3-fluorop  henyl)ethoxy]-5-(1-piperidin-4-yl-1H- pyrazol-4-yl)pyridin-2-ylamine;PF 02341066', '3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine;(R)-3-[1-(2,6-Dichloro-3-fluorop henyl)ethoxy]-5-(1-piperidin-4-yl-1H- pyrazol-4-yl)pyridin-2-ylamine;PF 02341066', '3-[(R)-1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Vorinostat","PubChemCID":"5311","SMILES":"C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO","Synonyms":"['Vorinostat', '149647-78-9', 'suberoylanilide hydroxamic acid', \"N-hydroxy-N'-phenyloctanediamide\", 'Zolinza', 'Suberanilohydroxamic acid', 'MK-0683', 'SAHA cpd', 'Vorinostat [USAN]', \"Octanediamide, N-hydroxy-N'-phenyl-\", \"N'-hydroxy-N-phenyloctanediamide\", 'OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE', 'CCRIS 8456', 'Zolinza (TN)', 'vorinostatum', 'NSC-701852', 'Vorinostat [USAN:INN]', 'NSC-748799', 'NSC-759852', '58IFB293JI', 'DTXSID6041133', 'CHEBI:45716', 'HSDB 7930', 'VORINOSTAT [MI]', 'VORINOSTAT [INN]', 'VORINOSTAT [JAN]', 'NSC701852', 'VORINOSTAT [VANDF]', 'VORINOSTAT [MART.]', 'VORINOSTAT [WHO-DD]', 'DTXCID4021133', 'VORINOSTAT [ORANGE BOOK]', 'NSC 701852', 'NSC 748799', 'NSC 759852', 'VORINOSTAT (MART.)', 'NHNPODA', 'suberoyl anilide hydroxamic acid', \"N Hydroxy N' phenyloctanediamide\", 'N1 Hydroxy N8 phenyloctanediamide', '18F-suberoylanilide hydroxamic acid', '18F Suberoylanilide Hydroxamic Acid', 'L01XX38', 'MSK-390', 'L-001079038', '682-505-1', 'waexfxrvdqxref-uhfffaoysa-n', 'SAHA', 'N1-hydroxy-N8-phenyloctanediamide', 'MK0683', 'Vorinostat (SAHA, MK0683)', \"N-Hyrdroxy-N'-phenyloctanediamide\", 'MFCD00945317', 'Vorinostat (SAHA)', 'SHH', 'CHEMBL98', 'WIN64652', 'NCGC00168085-01', 'NCGC00168085-02', 'Zolinza (TN) (Merck)', \"N-hydroxy-N'-phenyl-octane-1,8-diotic acid diamide\", 'Vorinostat MSD', 'SMR000486344', 'CAS-149647-78-9', 'SR-05000000373', 'Vorinostat (JAN/USAN)', 'MK 0683', 'UNII-58IFB293JI', 'SKI390', '4lxz', 'Vorinostat(SAHA)', 'Zolinza; SAHA', 'Vorinostat (GMP)', 'SAHA, Suberoylanilide hydroxamic acid', 'Vorinostat (SAHA)?', 'Vorinostat (Standard)', '1zz1', 'SW-064652', '8-(hydroxyamino)-8-oxo-N-phenyl-octanamide', 'cid_5311', 'SCHEMBL9018', 'Suberoylanilidehydroxamic Acid', 'MLS001065855', 'MLS006011941', 'GTPL6852', 'BDBM19149', 'Vorinostat  - Bio-X trade mark', 'Vorinostat (SAHA; MK0683)', \"n-hydroxy-n'-phenyl-octanediamide\", 'SUBERANILOHYDROXAMINIC ACID', '1t69', \"N-hydroxy-N''-phenyloctanediamide\", 'BCPP000018', 'GLXC-05791', 'HMS2219L20', 'HMS3264D20', 'HMS3327C12', 'HMS3426G03', 'HMS3650D09', 'HMS3654G11', 'HMS3715E22', 'HMS3745M03', 'Pharmakon1600-01502267', 'BCP01858', 'EX-A2745', 'HVB74948', 'SAHA, >=98% (HPLC)', 'Vorinostat,SAHA,Zolinza,MK-0683', 'Tox21_112605', 'Tox21_113623', 'Vorinostat,CAS:149647-78-9', 'HB1396', 'HY-10221G', 'HY-10221R', 'NSC748799', 'NSC759852', 'Octanediamide, N1-hydroxy-N8-phenyl', 's1047', 'SK1390', 'AKOS015966648', 'Tox21_112605_1', 'AC-1923', 'CCG-208659', 'CS-0589', 'DB02546', 'DG-0025', 'FH15949', 'SB17319', 'NCGC00168085-03', 'NCGC00168085-04', 'NCGC00168085-05', 'NCGC00168085-13', 'BP-25652', 'BP-30216', 'BV164560', 'HY-10221', 'SY009383', 'H1388', 'NS00068618', 'SW199536-4', 'D06320', 'EN300-120641', \"N-Hydroxy-N'-phenyl-octanediamide;Zolinza;SAHA\", 'AB00375377-07', 'AB00375377-08', 'AB00375377-09', 'AB01644613_25', 'Q905901', 'Vorinostat, SAHA, suberoylanilide hydroxamic acid', 'SR-05000000373-2', 'SR-05000000373-6', 'SR-05000000373-8', 'BRD-K81418486-001-01-2', 'BRD-K81418486-001-10-3', 'BRD-K81418486-001-12-9', 'BRD-K81418486-001-13-7', 'BRD-K81418486-001-17-8', 'BRD-K81418486-001-18-6', 'BRD-K81418486-001-44-2', 'BRD-K81418486-001-47-5', 'Z1530532755', 'N-Hydroxy-N inverted exclamation mark -phenyloctanediamide', \"N-Hydroxy-N'-phenyl-octanediamide; Suberoylanilide hydroxamic acid; SAHA\", '1227736-21-1']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Ceritinib","PubChemCID":"57379345","SMILES":"CC1=CC(=C(C=C1C2CCNCC2)OC(C)C)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)C(C)C)Cl","Synonyms":"['ceritinib', '1032900-25-6', 'LDK-378', 'NVP-LDK378-NX', '5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine', 'LDK 378', 'ceritinibum', 'UNII-K418KG2GET', 'K418KG2GET', 'NVP-LDK-378-NX', 'CHEBI:78432', 'DTXSID10725373', '2,4-Pyrimidinediamine, 5-chloro-N4-(2-((1-methylethyl)sulfonyl)phenyl)-N2-(5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl)-', '5-Chloro-N2-(5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl)-N4-(2-(propane-2-sulfonyl)phenyl)pyrimidine-2,4-diamine', 'compound 15b (PMID 23742252)', 'compound 15b [PMID 23742252]', '5-chloro-N2-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine-2,4-diamine', '5-chloro-N(2)-(5-methyl-4-(piperidin-4-yl)-2-((propan-2-yl)oxy)phenyl)-N(4)-(2-(propane-2-sulfonyl)phenyl)pyrimidine-2,4-diamine', '5-chloro-N(2)-{5-methyl-4-(piperidin-4-yl)-2-[(propan-2-yl)oxy]phenyl}-N(4)-[2-(propane-2-sulfonyl)phenyl]pyrimidine-2,4-diamine', 'N-(2-((5-chloro-2-((2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)propane-2-sulfonamide', 'N-{2-[(5-chloro-2-{[2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}propane-2-sulfonamide', 'DTXCID50676118', 'L01XE28', '5-Chloro-N2-(5-methyl-4-(piperidin-4-yl)-2-((propan-2-yl)oxy)phenyl)-N4-(2-(propan-2-ylsulfonyl)phenyl)pyrimidine-2,4-diamine', '5-CHLORO-N4-(2-((1-METHYLETHYL)SULFONYL)PHENYL)-N2-(5-METHYL-2-(1-METHYLETHOXY)-4-(PIPERIDIN-4-YL)PHENYL)PYRIMIDINE-2,4-DIAMINE', 'LDK378', 'ZYKADIA', 'Ceritinib (LDK378)', '5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine', 'CHEMBL2403108', '5-chloro-2-N-(5-methyl-4-piperidin-4-yl-2-propan-2-yloxyphenyl)-4-N-(2-propan-2-ylsulfonylphenyl)pyrimidine-2,4-diamine', '5-chloro-2-N-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-4-N-[2-(propane-2-sulfonyl)phenyl]pyrimidine-2,4-diamine', '5-Chloro-N~2~-[5-Methyl-4-(Piperidin-4-Yl)-2-(Propan-2-Yloxy)phenyl]-N~4~-[2-(Propan-2-Ylsulfonyl)phenyl]pyrimidine-2,4-Diamine', '5-Chloro-N4-[2-[(1methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine;5-Chloro-N4-[2-[(1methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine', 'Ceritinib(LDK378)', 'Ceritinib [USAN:INN]', 'C28H36ClN5O3S', 'Ceritinib[mi]', '2,4-Pyrimidinediamine, 5-chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-; 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine; Ceritinib; LDK 378; Zykadia', 'Zykadia (TN)', 'LDK378 Certinib', 'MFCD26142648', 'Ceritinib (Standard)', 'Ceritinib; LDK378', 'LDK378(Ceritinib)', 'CERITINIB [INN]', 'CERITINIB [JAN]', 'CERITINIB [MI]', 'Ceritinib(LDK378)?', 'CERITINIB [USAN]', 'CERITINIB [VANDF]', 'CERITINIB [WHO-DD]', 'Ceritinib (JAN/USAN/INN)', 'GTPL7397', 'SCHEMBL1014329', 'CERITINIB [ORANGE BOOK]', 'EX-A187', 'VERWOWGGCGHDQE-UHFFFAOYSA-N', 'HMS3652H22', 'HMS3673I17', 'HMS3747A11', 'BCP07611', 'BDBM50436850', 'HY-15656R', 'NSC776422', 'NSC777193', 'NSC800072', 'AKOS025396438', 'CCG-264762', 'CS-1406', 'DB09063', 'FC61431', 'GS-6356', 'NSC-776422', 'NSC-777193', 'NSC-800072', 'SB16490', 'NCGC00351603-10', 'NCGC00351603-13', 'NCGC00351603-15', 'AC-27469', 'HY-15656', 'NS00040660', 'S7083', 'SW219725-1', 'D10551', 'EN300-7404145', 'BRD-K22149900-001-01-3', 'BRD-K22149900-001-03-9', 'BRD-K22149900-001-05-4', 'Q21011233', 'Z2235802104', '4MK', '5-Chloro-N2-(2-isopropoxy-5-methyl-4-piperidin-4-yl-phenyl)-N4-[2-(propane-2-sulfonyl)-phenyl]-pyrimidine-2,4-diamine', '5-CHLORO-N2-(5-METHYL-4-(PIPERIDIN-4-YL)-2-(PROPAN-2-YLOXY)PHENYL)-N4-(2-(PROPANE-2- SULFONYL)PHENYL)PYRIMIDINE-2,4-DIAMINE', '5-CHLORO-N4-(2-((1-METHYLETHYL)SULFONYL)PHENYL)-N2-(5-METHYL-2-(1-METHYLETHOXY)-4- (PIPERIDIN-4-YL)PHENYL)PYRIMIDINE-2,4-DIAMINE']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Bosutinib","PubChemCID":"5328940","SMILES":"CN1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CC(=C3NC4=CC(=C(C=C4Cl)Cl)OC)C#N)OC","Synonyms":"['Bosutinib', '380843-75-4', 'SKI-606', 'SKI 606', 'SKI606', '4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile', '4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile', 'SK-606', 'UNII-5018V4AEZ0', 'CHEBI:39112', '5018V4AEZ0', 'EC 700-455-1', 'SK 606', 'BOSUTINIB (MART.)', 'BOSUTINIB [MART.]', '3-Quinolinecarbonitrile, 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-', '3-QUINOLINECARBONITRILE, 4-((2,4-DICHLORO-5-METHOXYPHENYL)AMINO)-6-METHYL-1-PIPERAZINYL)PROPOXY)-', 'bosutinibum', 'L01XE14', '4-Anilinobenzo(g)quinoline-3-carbonitrile', '4-anilino-3-quinolinecarbonitrile', 'Bosutinib (SKI-606)', 'BOSULIF', '4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile', 'Bosutinib (USAN)', 'Bosutinib [USAN]', 'MFCD07367846', '4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile', '4-(2,4-dichloro-5-methoxyanilino)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile', 'BOSUTINIB ISOMER 1', 'CHEMBL288441', '4-(2,4-dichloro-5-methoxyphenylamino)-6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)quinoline-3-carbonitrile', 'SKI-606)', 'Bosutinib [USAN:INN]', 'NCGC00241107-01', 'Bosutinib (Standard)', 'WAY-173606', 'Bosutinib,SKI-606', 'BOSUTINIB [INN]', 'Bosutinib (SKI606)', 'BOSUTINIB [MI]', 'BOSUTINIB [VANDF]', 'PF-5208763', 'BOSUTINIB [WHO-DD]', 'Bosutinib (SKI-606)?', 'MLS006011212', 'SCHEMBL158390', 'BDBM4552', 'GTPL5710', 'Bosutinib Isomer 1, Free Base', 'Bosutinib, >=98% (HPLC)', 'DTXSID10861568', 'EX-A391', 'UBPYILGKFZZVDX-UHFFFAOYSA-N', 'BCPP000318', 'HMS2043A22', 'HMS3244A03', 'HMS3244A04', 'HMS3244B03', 'HMS3651C03', 'HMS3672K11', 'HMS3743E09', 'K00615a', 'BCP01782', 'HB1323', 'HY-10158R', 'NSC765694', 'NSC799367', 'AKOS015902521', 'AC-2413', 'BCP9000446', 'CCG-208129', 'CS-0118', 'DB06616', 'FB19002', 'NSC-765694', 'NSC-799367', 'PB30881', 'SDCCGSBI-0646926.P001', 'NCGC00241107-03', 'NCGC00241107-05', '4-(2,4-dichloro-5-methoxy-anilino)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile', 'AS-11064', 'HY-10158', 'SMR002530350', 'NS00002757', 'S1014', 'SKI606; SKI 606; SK-I606', 'SW220197-1', 'D03252', 'AB01565836_03', 'EN300-7565041', 'Q894611', 'SR-01000941572', 'SR-01000941572-1', 'BRD-K99964838-001-01-0', 'BRD-K99964838-001-06-9', 'BRD-K99964838-001-11-9', 'BRD-K99964838-001-12-7', 'Z2216885221', '4-(2,4-Dichloro-5-methoxy-phenylamino)-6-methoxy-7-[3-(4-methyl-piperazin-1-yl)propoxy]quinoline-3-carbonitrile', '4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile;SKI 606']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"AZD1480","PubChemCID":"16659841","SMILES":"CC1=CC(=NN1)NC2=NC(=NC=C2Cl)N[C@@H](C)C3=NC=C(C=N3)F","Synonyms":"['AZD1480', '935666-88-9', 'AZD-1480', 'AZD 1480', 'UNII-KL2Z2TLF01', '5-Chloro-N2-[(1s)-1-(5-Fluoropyrimidin-2-Yl)ethyl]-N4-(5-Methyl-1h-Pyrazol-3-Yl)pyrimidine-2,4-Diamine', 'DTXSID50239469', 'AZD 1480 [WHO-DD]', '2,4-Pyrimidinediamine, 5-chloro-N2-((1S)-1-(5-fluoro-2-pyrimidinyl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)-', '5-chloro-2-N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-4-N-(3-methyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine', '5-chloro-2-N-((1S)-1-(5-fluoropyrimidin-2-yl)ethyl)-4-N-(3-methyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine', '5-chloro-N2-((1S)-1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine', '5-chloro-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine', 'DTXCID20161960', 'JAK2 INHIBITOR AZD1480', '(S)-5-chloro-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine', 'KL2Z2TLF01', 'CHEMBL1231124', '5-Chloro-N2-[(1S)-1-(5-fluoro-2-pyrimidinyl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine', '5-chloro-2-N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine', 'C14H14ClFN8', 'PDOQBOJDRPLBQU-QMMMGPOBSA-N', '2xa4', 'MLS006011153', 'GTPL5933', 'SCHEMBL3345019', 'EX-A450', 'BCPP000361', 'BCP02413', 'BDBM50335201', 'NSC756648', 'NSC799344', 's2162', 'AKOS027322548', 'BCP9000361', 'CCG-268021', 'DB12588', 'NC44330', 'NSC-756648', 'NSC-799344', 'NCGC00242486-01', 'NCGC00242486-02', 'NCGC00242486-05', 'AC-32807', 'AS-17011', 'HY-10193', 'SMR004702927', 'NS00072791', 'SW219486-1', 'BRD-K65928735-001-04-3', 'Q27074711', '935666-88-9, 1260222-79-4 (TFA)', '5-chloro-N~2~-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N~4~-(3-methyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine', 'AZ5']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Osi","PubChemCID":"156907049","SMILES":"C[C@]1(CCOC2=C1C=C(C=C2)Cl)C(=O)NC3=CN=CC4=CC=CC=C43","Synonyms":"['(4R)-6-chloro-N-(isoquinolin-4-yl)-4-methyl-3,4-dihydro-2H-1-benzopyran-4-carboxamide', 'EDJ-MED-e4b030d8-13', 'BDBM496244', 'OSi']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Niclosamide","PubChemCID":"4477","SMILES":"C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O","Synonyms":"['niclosamide', '50-65-7', 'Bayluscid', 'Phenasal', 'Cestocid', 'Devermin', 'Devermine', 'Helmiantin', 'Mansonil', 'Radeverm', 'Vermitid', 'Atenase', 'Iomesan', 'Iomezan', 'Lintex', 'Nasemo', 'Sagimid', 'Sulqui', 'Mato', 'Fedal-Telmin', 'Zestocarp', 'BAY 2353', 'Niclosamida', 'Chemagro 2353', 'Benzamide, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-', 'Niclosamidum', 'Niclosamide (anhydrous)', 'WR 46234', \"5-Chloro-2'-chloro-4'-nitrosalicylanilide\", 'HL 2447', 'Nitrophenyl chlorsalicylamide', 'Niclosamide, anhydrous', 'ENT 25823', 'CCRIS 3437', '2-Hydroxy-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide', 'HSDB 1572', 'N-(2-Chloro-4-nitrophenyl)-5-chlorosalicylamide', '2-Chloro-4-nitrophenylamide-6-chlorosalicylic acid', 'SR 73', 'Niclosamidum [INN-Latin]', \"Salicylanilide, 2',5-dichloro-4'-nitro-\", \"2',5-Dichlor-4'-nitro-salizylsaeureanilid\", 'UNII-8KK8CQ2K8G', 'Niclosamida [INN-Spanish]', 'EINECS 200-056-8', '8KK8CQ2K8G', 'NSC 178296', 'NSC-178296', 'BRN 2820605', 'Niclosamide Anhydrous', 'Niclosamidum anhydrous', \"5-Chloro-N-(2'-chloro-4'-nitrophenyl)salicylamide\", 'AI3-25823', '5-Chlorosalicyloyl-(o-chloro-p-nitranilide)', 'BAY-2353', 'B 2353', \"N-(2'-Chlor-4'-nitrophenyl)-5-chlorsalicylamid\", 'CHEBI:7553', \"N-(2'-Chloro-4'-nitrophenyl)-5-chlorosalicylamide\", 'VU0243604', 'Niclosamidum (INN-Latin)', 'Niclosamida (INN-Spanish)', 'NICLOSAMIDE (MART.)', 'NICLOSAMIDE [MART.]', 'NICLOSAMIDE (EP MONOGRAPH)', 'NICLOSAMIDE [EP MONOGRAPH]', 'NICLOSAMIDE, ANHYDROUS (EP IMPURITY)', 'NICLOSAMIDE, ANHYDROUS [EP IMPURITY]', 'Utosamide', 'P02DA01', \"2',5-dichloro-2-hydroxy-4'-nitrobenzanilide\", '200-056-8', '5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide', 'Niclocide', 'Tredemine', 'Fenasal', 'Yomesan', \"2',5-Dichloro-4'-nitrosalicylanilide\", 'Bayer 73', 'Bayer 2353', 'nicolsamide', 'MFCD00057597', 'DTXSID7040362', 'Radewerm', 'CAS-50-65-7', 'NCGC00015735-07', 'Niclosamide 100 microg/mL in Acetonitrile', 'C13H8Cl2N2O4', 'DTXCID5020362', 'Cestocide', 'Niclosamide [ISO]', 'Niclosamide [USAN:INN:BAN]', 'SR-01000076024', 'Niclosamide [BSI:ISO]', '5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-benzamide', 'Yomensan', 'niclo-samide', 'Niclocide (TN)', 'Prestwick_354', 'Niclosamide (GMP)', \"2',5-Dichlor-4'-nitro-salizylsaeureanilid [German]\", 'Mollutox (Salt/Mix)', \"N-(2'-Chlor-4'-nitrophenyl)-5-chlorsalicylamid [German]\", 'Niclosamide (Standard)', 'Spectrum_000239', 'Niclosamide (Niclocide)', 'Clonitralid (Salt/Mix)', 'Clonitralide (Salt/Mix)', 'NICLOSAMIDE [MI]', 'Prestwick0_000040', 'Prestwick1_000040', 'Prestwick2_000040', 'Prestwick3_000040', 'Spectrum2_001183', 'Spectrum3_000667', 'Spectrum4_000196', 'Spectrum5_001083', 'Lopac-N-3510', 'NICLOSAMIDE [INN]', 'Niclosamide (USAN/INN)', 'NICLOSAMIDE [HSDB]', 'NICLOSAMIDE [USAN]', 'NICLOSAMIDE [VANDF]', 'CHEMBL1448', 'Lopac0_000866', 'Oprea1_259151', 'SCHEMBL67182', 'BSPBio_000139', 'BSPBio_002333', 'KBioGR_000771', 'KBioSS_000719', 'NICLOSAMIDE [WHO-DD]', 'MLS002154181', 'DivK1c_000709', 'SPECTRUM1503265', 'SPBio_001225', 'SPBio_002060', 'BPBio1_000153', 'GTPL8494', 'NICLOSAMIDE [GREEN BOOK]', 'SCHEMBL18563900', 'WLN: WNR CG DMVR BQ EG', 'BDBM11242', 'HMS502D11', 'HY-B0497G', 'HY-B0497R', 'KBio1_000709', 'KBio2_000719', 'KBio2_003287', 'KBio2_005855', 'KBio3_001553', '5-Chloro-N-(2-chloro-4-nitro-phenyl)-2-hydroxy-benzamide', 'Niclosamide - CAS 50-65-7', 'NICLOSAMIDE [ORANGE BOOK]', 'NINDS_000709', 'BDBM513089', 'HMS1568G21', 'HMS2093A21', 'HMS2095G21', 'HMS2231H06', 'HMS3262N13', 'HMS3373P08', 'HMS3712G21', 'KUC107299N', 'Pharmakon1600-01503265', 'BCP22958', 'HY-B0497', 'Tox21_110209', 'Tox21_300749', 'Tox21_500866', 'BBL004110', 'CCG-39641', 'HB1435', 'NSC178296', 'NSC758440', 's3030', \"Salicylanilide,5-dichloro-4'-nitro-\", 'STK396676', '2,5-dichloro-4-nitrosalicylanilide ?', 'AKOS003589004', 'NICLOSAMIDE ANHYDROUS [WHO-IP]', 'Tox21_110209_1', 'AT15436', 'BCP9000068', 'DB06803', 'FN01544', 'KS-5210', 'LP00866', 'NSC-758440', 'SB19414', 'SDCCGSBI-0050841.P004', \"2',5'-Dichloro-4'-nitrosalicylanilide\", 'IDI1_000709', 'SMP2_000228', 'NCGC00015735-01', 'NCGC00015735-02', 'NCGC00015735-03', 'NCGC00015735-04', 'NCGC00015735-05', 'NCGC00015735-06', 'NCGC00015735-08', 'NCGC00015735-09', 'NCGC00015735-11', 'NCGC00015735-12', 'NCGC00015735-17', 'NCGC00015735-21', 'NCGC00015735-24', 'NCGC00094190-01', 'NCGC00094190-02', 'NCGC00094190-03', 'NCGC00094190-04', 'NCGC00254654-01', 'NCGC00261551-01', 'KSC-18-157-2', 'SMR000058390', 'SBI-0050841.P003', 'DB-051812', 'AB00052340', 'EU-0100866', 'NICLOSAMIDUM ANHYDROUS [WHO-IP LATIN]', 'NS00000613', 'EN300-92958', 'D00436', 'N 3510', 'AB00052340_08', 'AB00052340_09', 'A828227', 'Q418523', 'SR-01000076024-1', 'SR-01000076024-3', 'SR-01000076024-6', 'BRD-K35960502-001-06-9', 'BRD-K35960502-001-11-9', 'BRD-K35960502-001-19-2', 'BRD-K35960502-001-20-0', 'Z57902203', '5-chloranyl-N-(2-chloranyl-4-nitro-phenyl)-2-oxidanyl-benzamide', 'Niclosamide (anhydrous), European Pharmacopoeia (EP) Reference Standard', 'VUT']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Lapatinib","PubChemCID":"208908","SMILES":"CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl","Synonyms":"['Lapatinib', '231277-92-2', 'GW572016', 'Lapatinib [INN]', 'GW 572016', 'Lapatinib (INN)', 'GW-572016', 'Lapatinib [INN:BAN]', 'GSK 572016', 'N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine', 'UNII-0VUA21238F', 'DTXSID7046675', 'N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE', 'CHEBI:49603', 'HSDB 8209', '0VUA21238F', 'LAPATINIB [MI]', 'GSK572016', 'LAPATINIB [VANDF]', 'GSK-572016', 'GW-572016X', 'LAPATINIB [WHO-DD]', 'LAPATINIB [EMA EPAR]', 'n-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine', 'DTXCID5026675', 'GW-2016', '4-Quinazolinamine, N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-', 'N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamine', 'N-[3-chloro-4-(3-fluorobenzyloxy)phenyl]-6-[5-({[2-(methanesulfonyl)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine', 'lapatinibum', 'N-(3-CHLORO-4-((3-FLUOROBENZYL)OXY)PHENYL)-6-(5-(((2-(METHYLSULFONYL)ETHYL)AMINO)METHYL)-2-FURYL)-4-QUINAZOLINAMINE', 'N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-methanesulfonylethyl)amino)methyl)furan-2-yl)quinazolin-4-amine', 'N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-(((2-(methanesulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine', 'L01XE07', 'GW 2016', 'W572016', '878-720-7', 'N-(3-chloro-4-(((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-methylsulfonyl)ethyl)amino)methyl)-2-furyl)-4-quinazolinamine', 'Tykerb', 'Lapatinib base', 'MFCD09264194', 'Lapatinib free base', 'N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine', 'N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine', 'Lapatinib (free base)', '231277-92-2 (free base)', 'FMM', 'CHEMBL554', 'GW 282974X', 'NSC745750', '1210608-87-9', 'N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine', 'NCGC00167507-01', '913989-15-8', 'N-(3-Chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-((2-methylsulfonylethylamino)methyl)-2-furyl)quinazolin-4-amine', 'N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)furan-2-yl]quinazolin-4-amine', 'CAS-231277-92-2', 'C29H26ClFN4O4S', 'Lapatinib?', '1xkk', 'N-[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-[5-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine', 'N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine', 'Lapatinib ditosylate?', 'Lapatinib (Standard)', 'Lapatinib, Free base', 'nchembio866-comp20', 'Kinome_3684', 'Kinome_3685', 'SCHEMBL8100', 'Lapatinib (GW572016)', 'BDBM5445', 'cid_208908', 'GTPL5692', 'EX-A402', 'BCFGMOOMADDAQU-UHFFFAOYSA-N', 'BCPP000188', 'BCPP000189', 'GLXC-06463', 'HMS2089H10', 'HMS3244N06', 'HMS3244N10', 'HMS3244N14', 'HMS3744K11', 'Tykerb (TN) (Glaxo Smith Kline)', 'BCP01874', 'Lapatinib base - Bio-X trade mark', 'Tox21_112505', 'HY-50898R', 'NSC800780', 'AKOS005145766', 'Tox21_112505_1', 'AC-1314', 'BCP9000837', 'BCP9000838', 'CCG-270133', 'DB01259', 'FC12433', 'NSC-745750', 'NSC-800780', 'SB16918', 'SDCCGSBI-0634417.P003', 'NCGC00167507-02', 'NCGC00167507-03', 'NCGC00167507-04', 'NCGC00167507-09', 'AS-14065', 'BC164610', 'HY-50898', 'N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-((2-(methylsulfonyl)ethylamino)methyl)furan-2-yl)quinazolin-4-amine', 'N-(3-Chloro-4-{[(3-fluorophenyl)methyl]oxy}phenyl)-6-[5-({[2-(methylsulfonyl)ethyl]amino}methyl)-2-furanyl]-4-quinazolinamine', 'L0360', 'NS00003012', 'SW199101-5', 'D08108', 'EN300-117254', 'AB01273965-01', 'AB01273965-02', 'AB01273965-03', 'AB01273965_04', 'AB01273965_05', 'Q420323', 'SR-05000001472-1', 'BRD-K19687926-001-01-7', 'BRD-K19687926-001-04-1', 'BRD-K19687926-001-10-8', 'BRD-K19687926-379-02-5', 'BRD-K19687926-379-07-4', '1092929-10-6', 'GW572016;N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine', 'N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]-2-furyl] quinazolin-4-amine', 'N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine', 'N-{3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methane sulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine', 'N-{3-Chloro-4[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methane sulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Resveratrol","PubChemCID":"445154","SMILES":"C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O)O)O","Synonyms":"['resveratrol', '501-36-0', 'trans-resveratrol', \"3,4',5-Trihydroxystilbene\", '(E)-resveratrol', 'Resvida', \"3,4',5-Stilbenetriol\", \"3,4',5-Trihydroxy-trans-stilbene\", '5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol', 'Biofort', 'Cuspidatin', '(E)-5-(p-Hydroxystyryl)resorcinol', 'Resveratrol p 5', 'SRT 501', 'Resveratrol(e)-form', 'Melinjo resveratrol 20', 'CHEBI:45713', 'Srt 501m', '5-[2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol', '5-[(E)-2-(4-hydroxyphenyl)vinyl]benzene-1,3-diol', 'NSC 327430', 'NSC-327430', 'CCRIS 8952', 'DTXSID4031980', 'UNII-Q369O8926L', 'HSDB 7571', '5-((1E)-2-(4-Hydroxyphenyl)ethenyl)-1,3-benzenediol', 'Ca 1201', '1,3-Benzenediol, 5-(2-(4-hydroxyphenyl)ethenyl)-, (E)-', 'BIA 6-512', 'BIA-6-512', 'NSC327430', 'Q369O8926L', 'DTXCID2011980', 'CHEBI:27881', 'RESVERATROL (MART.)', 'RESVERATROL [MART.]', '1,3-Benzenediol, 5-((E)-2-(4-hydroxyphenyl)ethenyl)-', 'TRANS-RESVERATROL (USP-RS)', 'TRANS-RESVERATROL [USP-RS]', '5-((E)-2-(4-HYDROXYPHENYL)-ETHENYL) BENZENE-1,3 DIOL', 'trans Resveratrol', '5-(2-(4-hydroxyphenyl)ethenyl)benzene-1,3-diol', '5-((E)-2-(4-hydroxyphenyl)vinyl)benzene-1,3-diol', '1,3-Benzenediol, 5-[(E)-2-(4-hydroxyphenyl)ethenyl]-', '(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol', '5-((1E)-2-(4-hydroxyphenyl)ethenyl)benzene-1,3-diol', '1,3-Benzenediol, 5-(2-(4-hydroxyphenyl)-ethenyl)-, (E)-', '(E)-5-(4-Hydroxystyryl)benzene-1,3-diol', \"3,5,4'-Trihydroxystilbene\", '5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol', 'Resveratol', 'SRT-501', 'SRT501', \"3,5,4'-Trihydroxy-trans-stilbene\", \"trans-1,2-(3,4',5-Trihydroxydiphenyl)ethylene\", 'Resveratrol (Standard)', '1,3-Benzenediol, 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]-', 'MFCD00133799', 'CHEMBL165', '(E)-5-[2-(4-hydroxyphenyl)ethenyl]-1,3-benzendiol', 'MLS000069735', '133294-37-8', \"trans-3,4',5 - trihydroxystilbene\", \"trans-3,4',5-trihydroxystilbene\", 'SMR000058206', '5-[2-(4-hydroxyphenyl)vinyl]-1,3-benzenediol', \"3,4',5-trihydroxy-stilbene\", 'Resveratrol, natural', 'SR-01000000163', '375823-41-9', '1,3-Benzenediol, 5-[(1Z)-2-(4-hydroxyphenyl)ethenyl]-', 'Jotrol', '3fts', '4jaz', '4qer', 'Resveratrol, E-', 'KUC104385N', 'Stilbene, 2f', 'TaxusChinensisiRehd', 'NCGC00015894-02', 'CAS-501-36-0', 'STL', 'Prestwick_619', 'Resveratrol (GMP)', 'Resveratrol, trans-', 'KSC-10-164', 'Resveratrol, synthetic', 'RM-1812', 'Opera_ID_586', 'RESVERATROL [MI]', 'Prestwick2_000508', 'Prestwick3_000508', 'Spectrum5_000552', 'RESVERATROL [HSDB]', 'R 5010', 'RESVERATROL [VANDF]', 'Tocilizumab (anti-IL-6R)', 'Lopac0_001111', 'REGID_for_CID_6240', 'SCHEMBL19425', 'BSPBio_000435', 'BSPBio_001114', 'BSPBio_003461', 'RESVERATROL [WHO-DD]', 'MLS001055357', 'MLS001076538', 'MLS001424228', 'MLS002207121', 'MLS002222231', 'SPECTRUM1502223', 'CU-01000001503-3', 'BPBio1_000479', 'cid_445154', 'GTPL8741', 'SGCUT00007', 'Resveratrol, analytical standard', 'REGID_for_CID_445154', 'BDBM23926', 'Resveratrol, >=99% (HPLC)', '2l98', 'BCPP000091', 'HMS1362H15', 'HMS1569F17', 'HMS1792H15', 'HMS1921N04', 'HMS1990H15', 'HMS2052I09', 'HMS2096F17', 'HMS2232A18', 'HMS3263O04', 'HMS3403H15', 'HMS3412O14', 'HMS3649A20', 'HMS3676O14', 'BCP01416', 'MSK40018', 'to_000079', 'Tox21_110257', 'Tox21_201374', 'Tox21_303376', 'Tox21_501111', 'AC-727', 'BBL028252', 'CCG-38874', 'HB4055', 'HY-16561G', 'HY-16561R', 'LMPK13090005', 's1396', 'STL146386', 'AKOS005720936', 'Tox21_110257_1', 'CS-1050', 'DB02709', 'FR09412', 'KS-5047', 'LP01111', 'NC00349', 'SDCCGMLS-0002998.P003', 'SDCCGSBI-0051080.P003', 'IDI1_002152', 'NCGC00017352-05', 'NCGC00017352-06', 'NCGC00017352-07', 'NCGC00017352-08', 'NCGC00017352-09', 'NCGC00017352-10', 'NCGC00017352-11', 'NCGC00017352-12', 'NCGC00017352-13', 'NCGC00017352-14', 'NCGC00017352-15', 'NCGC00017352-16', 'NCGC00017352-17', 'NCGC00017352-18', 'NCGC00017352-19', 'NCGC00017352-24', 'NCGC00017352-31', 'NCGC00017352-37', 'NCGC00017352-39', 'NCGC00024003-00', 'NCGC00024003-04', 'NCGC00024003-05', 'NCGC00024003-06', 'NCGC00024003-07', 'NCGC00024003-08', 'NCGC00024003-09', 'NCGC00024003-10', 'NCGC00024003-11', 'NCGC00024003-12', 'NCGC00024003-13', 'NCGC00024003-14', 'NCGC00257465-01', 'NCGC00258925-01', 'NCGC00261796-01', '1ST40018', 'AS-12413', 'HY-16561', 'CS-0694771', 'EU-0101111', 'R0071', 'Resveratrol, Vetec(TM) reagent grade, 98%', 'SW196786-4', \"trans [2,5,4'-trihydroxydiphenyl] ethylene\", 'C03582', 'N88795', 'AB00052942-29', 'AB00052942_31', 'trans-Resveratrol 100 microg/mL in Acetonitrile', 'AE-641/30608044', 'Q407329', '5-[(E)-2-(4-Hydroxyphenyl)vinyl]-1,3-benzoldiol', 'SR-01000000163-3', 'SR-01000000163-4', 'SR-01000000163-9', '5-[(E)-2-(4-Hydroxyphenyl)ethenyl]benzol-1,3-diol', '5-[(E)-2-(4-Hydroxyphenyl)vinyl]-1,3-benzenediol', '5[(E)-2-(4-Hydroxyphenyl)-vinyl]benzene 1,3-diol', 'BRD-K25591257-001-01-2', 'BRD-K80738081-001-06-2', 'BRD-K80738081-001-07-0', 'BRD-K80738081-001-09-6', 'BRD-K80738081-001-10-4', 'BRD-K80738081-001-23-7', 'BRD-K80738081-001-42-7', 'BRD-K80738081-001-43-5', 'BRD-K80738081-001-44-3', 'BRD-K80738081-001-46-8', 'SR-01000000163-10', 'SR-01000000163-11', 'SR-01000000163-16', '(E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene', '(E)1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene', 'Resveratrol, certified reference material, TraceCERT(R)', 'Resveratrol, European Pharmacopoeia (EP) Reference Standard', '533C1DA0-4104-42B5-9D32-9265F40857E4', 'trans-Resveratrol, United States Pharmacopeia (USP) Reference Standard', \"3,4',5-Trihydroxy-trans-stilbene; 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol\", '(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol(E)-5-(2-(4-hydroxyphenyl)ethenyl)-1,3-benzenediol', '31100-06-8', 'InChI=1/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Dinaciclib","PubChemCID":"46926350","SMILES":"CCC1=C2N=C(C=C(N2N=C1)NCC3=C[N+](=CC=C3)[O-])N4CCCC[C@H]4CCO","Synonyms":"['Dinaciclib', '779353-01-4', 'SCH727965', 'SCH 727965', 'SCH-727965', 'MK-7965', 'DINACICLIB [INN]', 'DINACICLIB [USAN]', '4V8ECV0NBQ', 'DINACICLIB [WHO-DD]', '2-[(2S)-1-[3-ethyl-7-[(1-oxidopyridin-1-ium-3-yl)methylamino]pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-2-yl]ethanol', '(S)-3-((3-ethyl-5-(2-(2-hydroxyethyl)piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7-ylamino)methyl)pyridine 1-oxide', '2-Piperidineethanol, 1-(3-ethyl-7-(((1-oxido-3-pyridinyl)methyl)amino)pyrazolo(1,5-a)pyrimidin-5-yl)-, (2S)-', '3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]pyridin-1-ium-1-olate', 'Dinaciclib [USAN:INN]', 'dinaciclibum', '(S)-3-((3-ethyl-5-(2-(2-hydroxyethyl)piperidin-1-yl)pyrazolo(1,5-a)pyrimidin-7-ylamino)methyl)pyridine 1-oxide', '2-((2S)-1-(3-ethyl-7-((1-oxidopyridin-1-ium-3-yl)methylamino)pyrazolo(1,5-a)pyrimidin-5-yl)piperidin-2-yl)ethanol', '2-Piperidineethanol, 1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-, (2S)-', '3-(((3-ethyl-5-((2S)-2-(2-hydroxyethyl)piperidin-1-yl)pyrazolo(1,5-a)pyrimidin-7-yl)amino)methyl)pyridin-1-ium-1-olate', '3-(((3-ETHYL-5-((2S)-2-(2-HYDROXYETHYL)PIPERIDIN-1-YL)PYRAZOLO(1,5-A)PYRIMIDIN-7-YL)AMINO)METHYL)PYRIDINE 1-OXIDE', '3-[[[3-Ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl]amino]methyl]pyridine 1-oxide', 'CDK Inhibitor SCH 727965', '814-152-8', 'Dinaciclib (SCH727965)', '(S)-3-(((3-ethyl-5-(2-(2-hydroxyethyl)piperidin-1-yl)pyrazolo[1,5-a]pyrimidin-7-yl)amino)methyl)pyridine 1-oxide', '(2S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol', '1-[3-Ethyl-7[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2(s)-piperidineethanol', 'MFCD16037702', 'Dinaciclib (USAN/INN)', 'MLS006011034', 'GTPL7379', 'Dinaciclib (SCH727965)?', 'CHEMBL2103840', 'SCHEMBL12048446', 'CHEBI:95060', 'BDBM50139171', 'NSC747135', 'NSC764036', 'NSC800091', 's2768', 'AKOS030526898', 'CCG-268610', 'CS-0541', 'DB12021', 'NSC-727135', 'NSC-747135', 'NSC-764036', 'NSC-800091', 'SDCCGSBI-0654457.P001', 'NCGC00346656-13', 'AC-32835', 'AS-17017', 'FD158760', 'HY-10492', 'SMR004702827', 'DB-362421', 'SCH 727965,SCH727965, Dinaciclib', 'NS00072125', 'SW220016-1', 'D09604', 'EN300-23218095', 'BRD-K13662825-001-02-6', 'BRD-K13662825-001-07-5', 'Q15723091', '1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2S-piperidineethanol', '2-PIPERIDINEETHANOL, 1-(3-ETHYL-7-(((1-OXIDO-3-PYRIDINYL)METHYL)AMINO)PYRAZOLO(1,5- A)PYRIMIDIN-5-YL)-, (2S)-']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Verapamil","PubChemCID":"2520","SMILES":"CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC","Synonyms":"['VERAPAMIL', '52-53-9', 'Iproveratril', 'Dilacoran', 'Isoptimo', 'Verapamilo', 'Verapamilum', 'D-365', 'Verapamilum [INN-Latin]', 'Verapamilo [INN-Spanish]', 'dl-Verapamil', 'r,s-verapamil', 'CP-16533-1', 'Verapamil slow release', 'CCRIS 6749', '5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile', 'Ansyr', 'EINECS 200-145-1', 'UNII-CJ0O37KU29', 'CJ0O37KU29', 'Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-', 'NSC 272306NA', 'CP-16,533-1', 'EINECS 260-462-6', 'alpha-((N-Methyl-N-homoveratryl)-gamma-aminopropyl)-3,4-dimethoxyphenylacetonitrile', 'alpha-Isopropyl-alpha-((N-methyl-N-homoveratryl)-gamma-aminopropyl)-3,4-dimethoxyphenylacetonitrile', 'CP-165331', 'Valeronitrile, 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-', 'alpha-(3-((2-(3,4-Dimethoxyphenyl)ethyl)-methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile', 'CP 16533-1', 'D 365', 'HSDB 3928', 'NSC-272306NA', 'Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino) propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-', 'Verapamilum (INN-Latin)', 'Verapamilo (INN-Spanish)', '5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile', 'Verapamilum (Latin)', 'alpha-isopropyl-alpha-', 'CHEBI:9948', 'C08DA01', '(+-)-5-((3,4-DIMETHOXYPHENETHYL)METHYLAMINO)-2-(3,4-DIMETHOXYPHENYL)-2-ISOPROPYLVALERONITRILE', '200-145-1', 'alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino) propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-benzeneacetonitrile', 'alpha-(3-((2-(3,4-Dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile', 'rac-2-(3,4-dimethoxyphenyl)-5-((2-(3,4-dimethoxyphenyl)ethyl)(methyl)amino)-2-(propan-2-yl)pentanenitrile', 'cp-165331/cp-16533-1', 'Vasolan', 'Falicard', 'Finoptin', 'Lekoptin', 'Calan', 'Isotopin', 'Securon', 'Calcan', '(+/-)-VERAPAMIL', 'Izoptin', '2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile', '5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile', '2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile', 'Tarka', 'DTXSID9041152', 'CHEBI:77733', 'Anpec', 'NCGC00016083-09', 'Benzeneacetonitrile, .alpha.-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-.alpha.-(1-methylethyl)-', '(+/-)-Verapamil hydrochlorid', 'CP-165331 /  CP-16533-1', 'DTXCID7021152', 'Verapamil [USAN:INN:BAN]', '(+/-)-Verapamil;CP-16533-1', 'CAS-52-53-9', 'C27H38N2O4', 'Verapamil (USAN/INN)', 'Calan (Salt/Mix)', 'Akilen (Salt/Mix)', 'MFCD00056240', 'Isoptin (Salt/Mix)', 'Cordilox (Salt/Mix)', 'delta-365', 'VERAPAMIL [INN]', 'VERAPAMIL [MI]', 'Covera-HS (Salt/Mix)', 'VERAPAMIL [USAN]', '23313-68-0', 'Prestwick0_000141', 'Prestwick1_000141', 'Prestwick2_000141', 'Prestwick3_000141', 'Spectrum2_001740', 'Spectrum4_000906', 'Spectrum5_001786', 'VERAPAMIL [VANDF]', '()-Verapamil hydrochlorid', 'VERAPAMIL [WHO-DD]', 'CHEMBL6966', 'Lopac0_001237', 'SCHEMBL16742', 'BSPBio_000242', 'BSPBio_001513', 'BSPBio_002358', 'KBioGR_000233', 'KBioGR_001372', 'KBioGR_002343', 'KBioSS_000233', 'KBioSS_002346', '56949-77-0', 'MLS006011414', 'DivK1c_000399', 'SPBio_001820', 'SPBio_002181', 'BPBio1_000268', 'GTPL2406', 'CP 16533-1 (Verapamil)', 'SCHEMBL13287282', '(A+/-)-Verapamil hydrochloride', 'BDBM81939', 'KBio1_000399', 'KBio2_000233', 'KBio2_002343', 'KBio2_002801', 'KBio2_004911', 'KBio2_005369', 'KBio2_007479', 'KBio3_000465', 'KBio3_000466', 'KBio3_002823', '()-Verapamil;CP-16533-1', 'cMAP_000023', 'NINDS_000399', 'Bio1_000425', 'Bio1_000914', 'Bio1_001403', 'Bio2_000233', 'Bio2_000713', 'HMS1791L15', 'HMS1989L15', 'HMS2089H17', 'HMS3402L15', 'Tox21_110300', 'NSC_62969', 'STK538085', 'AKOS005468962', 'Tox21_110300_1', 'CCG-205311', 'DB00661', 'FV02354', 'SDCCGSBI-0051204.P005', 'CAS_52-53-9', 'IDI1_000399', 'IDI1_033983', 'NCGC00016083-04', 'NCGC00016083-05', 'NCGC00016083-06', 'NCGC00016083-07', 'NCGC00016083-08', 'NCGC00016083-10', 'NCGC00016083-11', 'NCGC00016083-13', 'NCGC00016083-14', 'NCGC00016083-15', 'NCGC00016083-16', 'NCGC00016083-17', 'NCGC00016083-18', 'NCGC00016083-20', 'NCGC00016083-25', 'NCGC00016083-34', 'NCGC00024710-04', 'NCGC00024710-05', 'NCGC00024710-06', 'NCGC00024710-07', 'NCGC00024710-08', 'NCGC00024710-09', 'NCGC00344584-01', '2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-(1-methylethyl) pentanenitrile', '2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-isopropyl-pentanenitrile', 'AC-16016', 'BP-21223', 'HY-14275', 'NCI60_020143', 'SMR001550201', 'SBI-0051204.P003', '(-)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile', 'DB-349548', 'AB00053495', 'CS-0002967', 'NS00000313', 'C07188', 'D02356', 'E75969', 'EN300-708774', 'AB00053495-20', 'AB00053495_21', 'L001330', 'Q410291', 'BRD-A09533288-001-02-7', 'BRD-A09533288-003-05-6', 'BRD-A09533288-003-29-6', 'BRD-A09533288-003-31-2', 'F2173-0851', 'VERAPAMIL, Dexverapamil, Verapamyl hydrochloride, VERAPAMIL HYDROCHLORIDE', '.alpha.-((N-Methyl-N-homoveratryl)-.gamma.-aminopropyl)-3,4-dimethoxyphenylacetonitrile', '(+/-)-5-((3,4-DIMETHOXYPHENETHYL)METHYLAMINO)-2-(3,4-DIMETHOXYPHENYL)-2-ISOPROPYLVALERONITRILE', '2-(3,4-Dimethoxyphenyl)-5-((2-(3,4-dimethoxyphenyl)ethyl)(methyl)amino)-2-isopropylpentanenitrile, (+/-)-', '2-(3,4-Dimethoxyphenyl)-5-[[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino]-2-isopropylpentanenitrile #']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Cpi","PubChemCID":"736316","SMILES":"C1CCN[C@H](C1)C(=O)O","Synonyms":"['1723-00-8', 'D-pipecolic acid', '(R)-Piperidine-2-carboxylic acid', 'D-Pipecolinic acid', 'D-Homoproline', '(2R)-piperidine-2-carboxylic acid', '(+)-Pipecolic acid', 'Pipecolic acid, (+)-', '(R)-pipecolic acid', '(R)-Pipecolinic acid', 'D-(+)-Pipecolic acid', '2-Piperidinecarboxylic acid, (2R)-', '6-CARBOXYPIPERIDINE', '(+)-Pipecolinic acid', '(r)-(+)-pipecolic acid', 'CHEBI:41582', 'XPO6784Z20', 'EINECS 217-024-4', '(R)-2-CARBOXYPIPERIDINE', 'DTXSID401347687', 'PIPECOLIC ACID, D-(+)-', 'PIPECOLIC ACID D-FORM [MI]', 'PIPECOLIC ACID D-FORM', 'DTXCID701776413', 'h-d-hopro-oh', 'D-piperidine-2-carboxylic acid', 'd(+)-pipecolinic acid', 'CHEMBL1231898', '(D)-PIPECOLIC ACID', 'MFCD00064346', 'd-(+)-pipecolinic acid', 'UNII-XPO6784Z20', '(R)-2-Piperidinecarboxylic acid', '(2R)-2-Piperidinecarboxylic acid', 'D-hPro-OH', 'D-(+)-Pipercolic acid', 'D-(+)- Pipecolic acid', 'D-Pipecolinic acid, 99%', '(d)-(+)-pipercolic acid', 'SCHEMBL58642', '(2r)-(+)-pipecolinic acid', '(R)-(+/-)-Nipecotic acid', '2-(R)-piperidine carboxylic acid', '2 -(R)-piperidine carboxylic acid', 'CS-D1144', 'HY-Y0181', '(R)-()-2-Piperidinecarboxylic acid', 'BDBM50357228', 'AKOS005258386', 'AKOS006238612', 'AC-2836', 'DS-1095', '(2r)-(+)-2-piperidinecarboxylic acid', 'AC-15333', 'AC-16524', 'CPI', 'DB-344888', 'NS00015339', 'P1830', 'EN300-91921', 'Q27104476', 'Z1741967418']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Flecainide","PubChemCID":"3356","SMILES":"C1CCNC(C1)CNC(=O)C2=C(C=CC(=C2)OCC(F)(F)F)OCC(F)(F)F","Synonyms":"['flecainide', '54143-55-4', 'Flecainida', 'Flecainidum', '(+-)-Flecainide', 'Flecainidum [INN-Latin]', 'Flecainida [INN-Spanish]', 'N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide', 'CCRIS 313', 'Benzamide, N-(2-piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)-', 'NSC-719273', 'UNII-K94FTS1806', 'DTXSID8023054', 'CHEBI:75984', 'K94FTS1806', 'THN-102 COMPONENT FLECAINIDE', 'N-(2-Piperidylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide', 'DTXCID403054', 'THN102 COMPONENT FLECAINIDE', 'NSC 719273', 'Flecainidum (INN-Latin)', 'Flecainida (INN-Spanish)', 'C01BC04', 'Flecaine', 'N-(piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide', 'Tambocor', 'Flecainide (INN)', 'MFCD00864713', 'CHEMBL652', 'NCGC00015443-06', 'FLECAINIDE [INN]', 'N-[(piperidin-2-yl)methyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide', 'Flecainide [INN:BAN]', 'C17H20F6N2O3', 'CAS-54143-55-4', '(+/-)-flecainide', 'rac-Flecainide', 'Flecainide (Standard)', 'FLECAINIDE [MI]', 'Prestwick0_000735', 'Prestwick1_000735', 'Prestwick2_000735', 'Prestwick3_000735', 'FLECAINIDE [VANDF]', 'FLECAINIDE [WHO-DD]', 'Lopac0_000546', 'SCHEMBL14970', 'BSPBio_000690', 'BSPBio_001317', 'KBioGR_000037', 'KBioSS_000037', 'SPBio_002629', 'BPBio1_000760', 'GTPL2560', 'BCBcMAP01_000189', 'KBio2_000037', 'KBio2_002605', 'KBio2_005173', 'KBio3_000073', 'KBio3_000074', 'Bio1_000375', 'Bio1_000864', 'Bio1_001353', 'Bio2_000037', 'Bio2_000517', 'HMS1791B19', 'HMS1989B19', 'HMS2089E17', 'BCP24373', 'HY-W010950R', 'Tox21_110151', 'BDBM50131434', 'N-(piperidin-2-ylmethyl)-2,5-bis[(2,2,2-trifluoroethyl)oxy]benzamide', 'NSC782306', 'AKOS015962192', 'Tox21_110151_1', 'CCG-204636', 'CS-W011666', 'DB01195', 'FF27520', 'HY-W010950', 'NSC-782306', 'SB19141', 'IDI1_033787', 'SMP1_000074', 'NCGC00015443-04', 'NCGC00015443-05', 'NCGC00015443-07', 'NCGC00015443-08', 'NCGC00015443-10', 'NCGC00015443-11', 'NCGC00015443-12', 'NCGC00015443-13', 'NCGC00015443-14', 'NCGC00015443-15', 'NCGC00015443-17', 'NCGC00025175-03', 'NCGC00025175-04', 'NCGC00025175-05', 'NCGC00025175-06', 'AC-16019', 'AC-31101', 'AS-71745', 'SY269348', 'DB-052496', 'DB-230917', 'AB00513907', 'NS00010512', 'C07001', 'D07962', 'EN300-144572', 'F18100', 'AB00384356-13', 'Q421381', 'BRD-A09472452-001-02-8', 'BRD-A09472452-015-03-6', 'BRD-A09472452-015-11-9', 'BRD-A09472452-015-22-6', 'BRD-A09472452-015-23-4', '2,5-bis(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)benzamide', '2,5-bis(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)-benzamide', 'N-(2-Piperidinylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide #', 'N-Piperidin-2-ylmethyl-2,5-bis-(2,2,2-trifluoro-ethoxy)-benzamide', 'N-Piperidin-2-ylmethyl-2,5-bis-(2,2,2-trifluoro-ethoxy)-benzamide (Flecainide)', 'N-Piperidin-2-ylmethyl-2,5-bis-(2,2,2-trifluoro-ethoxy)-benzamide(Flecainide)', 'N-Piperidin-2-ylmethyl-2,5-bis-(2,2,2-trifluoro-ethoxy)-benzamide(Flecanide)']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Flavopiridol","PubChemCID":"5287969","SMILES":"CN1CC[C@@H]([C@@H](C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O","Synonyms":"['Flavopiridol', 'Alvocidib', '146426-40-6', 'Alvocidib freebase', 'L86-8275', 'L 868275', 'L-868275', 'Flavopiridol (Alvocidib)', 'HMR 1274', '2-(2-chlorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one', '2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one', '2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]chromen-4-one', '4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-', 'L 86-8275', 'CHEMBL428690', '45AD6X575G', '2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE', 'Alvocidib [INN]', 'FLAVO', 'Flavoperidol', '2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidyl]chromen-4-one', 'Alvocidib [USAN]', 'Alvocidib [USAN:INN]', 'alvocidibum', 'UNII-45AD6X575G', 'CCRIS 9399', 'NSC 649890 HCl', '4H-1-BENZOPYRAN-4-ONE, 2-(2-CHLOROPHENYL)-5,7-DIHYDROXY-8-((3S,4R)-3-HYDROXY-1-METHYL-4-PIPERIDINYL)-', '(-)cis-5,7-Dihydroxy-2-(2-chlorophenyl)-8-(4-(3-hydroxy-1-methyl)piperidinyl)-4H-1-benzopyran-4-one', '1c8k', '1e1y', 'Alvocidib (USAN/INN)', 'FLAVOPIRIDOL [MI]', 'ALVOCIDIB [MART.]', 'ALVOCIDIB [WHO-DD]', 'SCHEMBL3652', 'Flavopiridol HCl; Alvocidib', 'BDBM5655', 'GTPL5680', 'CHEBI:47344', 'DTXSID20904970', 'EX-A1901', 'Flavopiridol,Alvocidib, HMR-1275', 'HMR-1274', 'MFCD20501884', 'NSC799330', 's1230', 'AKOS022182942', 'CCG-268666', 'DB03496', 'FF65024', 'NSC-799330', 'SDCCGSBI-0646527.P001', '(-)-cis-5,7-dihydroxy-2-(2-chlorophenyl)-8-(4-(3-hydroxy-1-methyl)piperidinyl)-4H-1-benzopyran-4-one', '4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-((3R,4S)-3-hydroxy-1-methyl-4-piperidinyl)-, rel-(-)-', '4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-(3-hydroxy-1-methyl-4-piperidinyl)-, cis-(-)-', 'AS-74761', 'HY-10005', 'NS00071644', 'D09868', 'EN300-22867972', 'Q4063441', 'BRD-K87909389-001-01-2', 'BRD-K87909389-003-03-4', 'BRD-K87909389-003-04-2', '(-)-CIS-2-(2-CHLOROPHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYLPIPERIDIN-4-YL)-4H-1-BENZOPYRAN-4-ONE', '4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-2,3-dihydro-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Okadaic acid","PubChemCID":"446512","SMILES":"C[C@@H]1CC[C@]2(CCCCO2)O[C@@H]1[C@@H](C)C[C@@H]([C@@H]3C(=C)[C@H]([C@H]4[C@H](O3)CC[C@]5(O4)CC[C@@H](O5)/C=C/[C@@H](C)[C@@H]6CC(=C[C@@]7(O6)[C@@H](CC[C@H](O7)C[C@](C)(C(=O)O)O)O)C)O)O","Synonyms":"['okadaic acid', '78111-17-8', 'CHEBI:44658', 'OKADAIC ACID [MI]', 'OKADAIC ACID [HSDB]', '9,10-Deepithio-9,10-didehydroacanthifolicin', '35-DEMETHYL-DTX 1', 'DTXSID60880002', 'Acanthifolicin, 9,10-deepithio-9,10-didehydro-', '35-DEMETHYLDINOPHYSISTOXIN 1', 'CCRIS 3329', 'NSC-677083', 'HSDB 7243', 'Ocadaic Acid', \"(2R)-3-[(2S,5R,6R,8S)-8-[(2R,3E)-4-[(2R,4'aR,5R,6'S,8'R,8'aS)-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-7'-methylidene-hexahydro-3'H-spiro[oxolane-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl]-5-hydroxy-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-hydroxy-2-methylpropanoic acid\", 'UNII-1W21G5Q4N2', 'halochondrine A', 'PL toxin II', \"(.ALPHA.R,2S,5R,6R,8S)-.ALPHA.,5-DIHYDROXY-.ALPHA.,10-DIMETHYL-8-((1R,2E)-1-METHYL-3-((2R,4'AR,5R,6'S,8'R,8'AS)-OCTAHYDRO-8'-HYDROXY-6'-((1S,3S)-1-HYDROXY-3-((2S,3R,6S)-3-METHYL-1,7-DIOXASPIRO(5.5)UNDEC-2-YL)BUTYL)-7'-METHYLENESPIRO(FURAN-2(3H),2'(3'H)-PYRANO(3,2-B)PYRAN)-5-YL)-2-PROPEN-1-YL)-1,7-DIOXASPIRO(5.5)UNDEC-10-ENE-2-PROPANOIC ACID\", \"(2R)-3-((2S,6R,8S,11R)-2-((E,2R)-4-((2S,2'R,4R,4AS,6R,8AR)-4-HYDROXY-2-((1S,3S)-1-HYDROXY-3-((2S,3R,6S)-3-METHYL-1,7-DIOXASPIRO(5.5)UNDECAN-2-YL)BUTYL)-3-METHYLIDENESPIRO(4A,7,8,8A-TETRAHYDRO-4H-PYRANO(3,2-B)PYRAN-6,5'-OXOLANE)-2'-YL)BUT-3-EN-2-YL)-11-HYDROXY-4-METHYL-1,7-DIOXASPIRO(5.5)UNDEC-4-EN-8-YL)-2-HYDROXY-2-METHYLPROPANOIC ACID\", \"(2R)-3-[(2S,6R,8S,11R)-2-[(E,2R)-4-[(2S,2'R,4R,4aS,6R,8aR)-4-hydroxy-2-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,5'-oxolane]-2'-yl]but-3-en-2-yl]-11-hydroxy-4-methyl-1,7-dioxaspiro[5.5]undec-4-en-8-yl]-2-hydroxy-2-methylpropanoic acid\", \"1,7-DIOXASPIRO(5.5)UNDEC-10-ENE-2-PROPANOIC ACID, .ALPHA.,5-DIHYDROXY-.ALPHA.,10-DIMETHYL-8-((1R,2E)-1-METHYL-3-((2R,4'AR,5R,6'S,8'R,8'AS)-OCTAHYDRO-8'-HYDROXY-6'-((1S,3S)-1-HYDROXY-3-((2S,3R,6S)-3-METHYL-1,7-DIOXASPIRO(5.5)UNDEC-2-YL)BUTYL)-7'-METHYLENESPIRO(FURAN-2(3H),2'(3'H)-PYRANO(3,2-B)PYRAN)-5-YL)-2-PROPEN-1-YL)-, (.ALPHA.R,2S,5R,6R,8S)-\", 'Okadaate', 'NSC 677083', '1,7-Dioxaspiro', \"(2R)-2-hydroxy-3-((2S,5R,6R,8S)-5-hydroxy-8-((2R,3E)-4-((2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-((1S,3S)-1-hydroxy-3-((2S,3R,6S)-3-methyl-1,7-dioxaspiro(5.5)undec-2-yl)butyl)-7'-methylideneoctahydro-3H,3'H-spiro(furan-2,2'-pyrano(3,2-b)pyran)-5-yl)but-3-en-2-yl)-10-methyl-1,7-dioxaspiro(5.5)undec-10-en-2-yl)-2-methylpropanoic acid\", \"(2R)-2-hydroxy-3-{(2S,5R,6R,8S)-5-hydroxy-8-[(2R,3E)-4-((2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl)but-3-en-2-yl]-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl}-2-methylpropanoic acid\", \"(2R)-3-((2S,5R,6R,8S)-8-((2R,3E)-4-((2R,4'AR,5R,6's,8'r,8'ar)-8'-hydroxy-6'-((1S,3S)-1-hydroxy-3-((2S,3R,6S)-3-methyl-1,7-dioxaspiro(5.5)undecan-2-yl)butyl)-7'-methylidene-hexahydro-3'H-spiro(oxolane-2,2'-pyrano(3,2-b)pyran)-5-yl)but-3-en-2-yl)-5-hydroxy-10-methyl-1,7-dioxaspiro(5.5)undec-10-en-2-yl)-2-hydroxy-2-methylpropanoate\", \"(2R)-3-((2S,5R,6R,8S)-8-((2R,3E)-4-((2R,4'aR,5R,6'S,8'R,8'aS)-8'-hydroxy-6'-((1S,3S)-1-hydroxy-3-((2S,3R,6S)-3-methyl-1,7-dioxaspiro(5.5)undecan-2-yl)butyl)-7'-methylidene-hexahydro-3'H-spiro(oxolane-2,2'-pyrano(3,2-b)pyran)-5-yl)but-3-en-2-yl)-5-hydroxy-10-methyl-1,7-dioxaspiro(5.5)undec-10-en-2-yl)-2-hydroxy-2-methylpropanoic acid\", \"(2R)-3-((2S,6R,8S,11R)-2-((E,2R)-4-((2S,2'R,4R,4aS,6R,8aR)-4-hydroxy-2-((1S,3S)-1-hydroxy-3-((3R,6S)-3-methyl-1,7-dioxaspiro(5.5)undecan-2-yl)butyl)-3-methylidenespiro(4a,7,8,8a-tetrahydro-4H-pyrano(3,2-b)pyran-6,5'-oxolane)-2'-yl)but-3-en-2-yl)-11-hydroxy-4-methyl-1,7-dioxaspiro(5.5)undec-4-en-8-yl)-2-hydroxy-2-methylpropanoic acid\", \"(2R)-3-[(2S,5R,6R,8S)-8-[(2R,3E)-4-[(2R,4'AR,5R,6's,8'r,8'ar)-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-7'-methylidene-hexahydro-3'H-spiro[oxolane-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl]-5-hydroxy-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-hydroxy-2-methylpropanoate\", \"(2R)-3-[(2S,6R,8S,11R)-2-[(E,2R)-4-[(2S,2'R,4R,4aS,6R,8aR)-4-hydroxy-2-[(1S,3S)-1-hydroxy-3-[(3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,5'-oxolane]-2'-yl]but-3-en-2-yl]-11-hydroxy-4-methyl-1,7-dioxaspiro[5.5]undec-4-en-8-yl]-2-hydroxy-2-methylpropanoic acid\", \"1,7-DIOXASPIRO(5.5)UNDEC-10-ENE-2-PROPANOIC ACID, ALPHA,5-DIHYDROXY-ALPHA,10-DIMETHYL-8-((1R,2E)-1-METHYL-3-((2R,4'AR,5R,6'S,8'R,8'AS)-OCTAHYDRO-8'-HYDROXY-6'-((1S,3S)-1-HYDROXY-3-((2S,3R,6S)-3-METHYL-1,7-DIOXASPIRO(5.5)UNDEC-2-YL)BUTYL)-7'-METHYLENESPIRO(FURAN-2(3H),2'(3'H)-PYRANO(3,2-B)PYRAN)-5-YL)-2-PROPEN-1-YL)-, (ALPHAR,2S,5R,6R,8S)-\", \"1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, alpha,5-dihydroxy-alpha,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (alphaR,2S,5R,6R,8S)-\", \"2-hydroxy-3-(5-hydroxy-8-((3E)-4-(8'-hydroxy-6'-(1-hydroxy-3-(3-methyl-1,7-dioxaspiro(5.5)undecan-2-yl)butyl)-7'-methylidene-hexahydro-3'H-spiro(oxolane-2,2'-pyrano(3,2-b)pyran)-5-yl)but-3-en-2-yl)-10-methyl-1,7-dioxaspiro(5.5)undec-10-en-2-yl)-2-methylpropanoic acid\", \"2-hydroxy-3-{5-hydroxy-8-[(3E)-4-[8'-hydroxy-6'-(1-hydroxy-3-{3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl}butyl)-7'-methylidene-hexahydro-3'H-spiro[oxolane-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl]-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl}-2-methylpropanoic acid\", \"methyl (2R)-3-((2S,6R,8S,11R)-2-((2R)-4-((2S,2'S,4R,4aS,6R,8aR)-2-((1S,3S)-3-((2S,3R,6R,11R)-3,11-dimethyl-1,7-dioxaspiro(5.5)undecan-2-yl)-1-hydroxybutyl)-4-hydroxy-3-methylidenespiro(4a,7,8,8a-tetrahydro-4H-pyrano(3,2-b)pyran-6,5'-oxolane)-2'-yl)butan-2-yl)-11-hydroxy-4-methyl-1,7-dioxaspiro(5.5)undec-4-en-8-yl)-2-hydroxy-2-methylpropanoate\", \"methyl (2R)-3-[(2S,6R,8S,11R)-2-[(2R)-4-[(2S,2'S,4R,4aS,6R,8aR)-2-[(1S,3S)-3-[(2S,3R,6R,11R)-3,11-dimethyl-1,7-dioxaspiro[5.5]undecan-2-yl]-1-hydroxybutyl]-4-hydroxy-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,5'-oxolane]-2'-yl]butan-2-yl]-11-hydroxy-4-methyl-1,7-dioxaspiro[5.5]undec-4-en-8-yl]-2-hydroxy-2-methylpropanoate\", 'DTXCID901021604', \"(ALPHAR,2S,5R,6R,8S)-ALPHA,5-DIHYDROXY-ALPHA,10-DIMETHYL-8-((1R,2E)-1-METHYL-3-((2R,4'AR,5R,6'S,8'R,8'AS)-OCTAHYDRO-8'-HYDROXY-6'-((1S,3S)-1-HYDROXY-3-((2S,3R,6S)-3-METHYL-1,7-DIOXASPIRO(5.5)UNDEC-2-YL)BUTYL)-7'-METHYLENESPIRO(FURAN-2(3H),2'(3'H)-PYRANO(3,2-B)PYRAN)-5-YL)-2-PROPEN-1-YL)-1,7-DIOXASPIRO(5.5)UNDEC-10-ENE-2-PROPANOIC ACID\", \"1,7-Dioxaspiro(5.5)undec-10-ene-2-propanoic acid, alpha,5-dihydroxy-alpha,10-dimethyl-8-((1R,2E)-1-methyl-3-((2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-((1S,3S)-1-hydroxy-3-((2S,3R,6S)-3-methyl-1,7-dioxaspiro(5.5)undec-2-yl)butyl)-7'-methylenespiro(furan-2(3H),2'(3'H)-pyrano(3,2-b)pyran)-5-yl)-2-propenyl)-, (alphaR,2S,5R,6R,8S)-\", \"1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, .alpha.,5-dihydroxy-.alpha.,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, (.alpha.R,2S,5R,6R,8S)-\", '616-589-8', \"(2r)-3-((2s,6r,8s,11r)-2-((e,2r)-4-((2s,2's,4r,4as,6r,8ar)-4-hydroxy-2-((1s,3s)-1-hydroxy-3-((2s,3r,6s)-3-methyl-1,7-dioxaspiro(5.5)undecan-2-yl)butyl)-3-methylidenespiro(4a,7,8,8a-tetrahydro-4h-pyrano(3,2-b)pyran-6,5'-oxolane)-2'-yl)but-3-en-2-yl)-11-hydroxy-4-methyl-1,7-dioxaspiro(5.5)undec-4-en-8-yl)-2-hydroxy-2-methylpropanoic acid\", \"(2r)-3-[(2s,6r,8s,11r)-2-[(e,2r)-4-[(2s,2's,4r,4as,6r,8ar)-4-hydroxy-2-[(1s,3s)-1-hydroxy-3-[(2s,3r,6s)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4h-pyrano[3,2-b]pyran-6,5'-oxolane]-2'-yl]but-3-en-2-yl]-11-hydroxy-4-methyl-1,7-dioxaspiro[5.5]undec-4-en-8-yl]-2-hydroxy-2-methylpropanoic acid\", 'qndvlzjodhbufm-pdjkbhkbsa-n', 'CHEMBL280487', 'OKA', '1W21G5Q4N2', 'Okadaic acid from Prorocentrum concavum', '1jk7', 'Okadaic acid (Standard)', 'Probes1_000180', 'SCHEMBL131485', 'OA and NSC 677083', 'CHEMBL158524', 'GTPL5349', 'HY-N6785R', '1u32', 'QNDVLZJODHBUFM-WFXQOWMNSA-N', 'HY-N6785', 'BDBM50097634', 'BDBM50110676', 'EX-A10340', 'HB0468', 'MFCD00083455', 'AKOS040742329', 'AT32065', 'DB02169', 'FO73140', 'DA-66318', 'CS-0014219', 'Q414042', 'Okadaic acid from Prorocentrum concavum, 92-100% (HPLC)', 'Okadaic acid from Prorocentrum concavum, >=90% (HPLC), translucent film', \"(2R)-2-hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(1R,2E)-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]-1-methylprop-2-en-1-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoic acid\", \"(2R)-3-[(2S,5R,6R,8S)-8-{(2R,3E)-4-[(2R,4'aR,5R,6'S,8'R,8'aS)-8'-Hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl}-7'-methylidenehexahydro-3'H-spiro[oxolane-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl}-5-hydroxy-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-hydroxy-2-methylpropanoic acid\", \"1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, .alpha,5-dihydroxy-.alpha.,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (.alpha.R,2S,5R,6R,8S)-\"]","Type":"small molecule"},{"Action":"not found","PerturbationName":"Sp600125","PubChemCID":"8515","SMILES":"C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O","Synonyms":"['129-56-6', '1,9-Pyrazoloanthrone', 'SP600125', 'Pyrazolanthrone', 'Dibenzo[cd,g]indazol-6(2H)-one', 'SP 600125', 'Anthra[1,9-cd]pyrazol-6(2H)-one', 'JNK Inhibitor II', 'ANTHRA(1,9-cd)PYRAZOL-6(2H)-ONE', 'NSC 75890', 'NSC75890', 'EINECS 204-955-6', 'BRN 0746890', 'DTXSID2040525', 'UNII-1TW30Y2766', 'CHEBI:90695', '1TW30Y2766', 'CI 70300', 'DTXCID0020525', 'dibenzo(cd,g)indazol-6(2H)-one', '14,15-diazatetracyclo[7.6.1.0^{2,7}.0^{13,16}]hexadeca-1(15),2(7),3,5,9,11,13(16)-heptaen-8-one', '14,15-diazatetracyclo(7.6.1.0^(2,7).0^(13,16))hexadeca-1(15),2(7),3,5,9,11,13(16)-heptaen-8-one', 'acpoujidantyho-uhfffaoysa-n', 'Pyrazoleanthrone', 'SP-600125', 'C.I. 70300', '2H-Dibenzo[cd,g]indazol-6-one', 'NSC-75890', '2h-dibenzo(cd,g)indazol-6-one', 'MFCD00022289', 'CHEMBL7064', 'MLS002693964', 'Anthra-1,9-pyrazol-6-none', '14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1(15),2,4,6,9(16),10,12-heptaen-8-one', 'NCGC00015958-03', 'SMR000015440', 'SR-01000075840', '1pmv', '2zmd', 'Kinome_3844', 'Tocris-1496', 'BiomolKI_000068', 'Lopac-S-5567', 'BiomolKI2_000072', 'cid_8515', 'CBiol_002049', 'Lopac0_000473', 'BMK1-G8', 'BSPBio_001066', 'ChemBiol10705 Compound 4', 'KBioGR_000406', 'KBioSS_000406', 'JMC517015 Compound 2', 'MLS002153267', 'MLS006011577', 'SCHEMBL170980', 'anthra[1,9-cd]pyrazol-6-one', 'GTPL5273', 'Pyrazolanthrone (SP600125)', 'CHEMBL1725279', 'SCHEMBL15583517', 'BCBcMAP01_000053', 'BDBM16018', 'dibenz[cd,g]indazol-6(2h)-one', 'KBio2_000406', 'KBio2_002974', 'KBio2_005542', 'KBio3_000771', 'KBio3_000772', 'Bio1_000335', 'Bio1_000824', 'Bio1_001313', 'Bio2_000373', 'Bio2_000853', 'GLXC-03091', 'HMS1362F07', 'HMS1667K13', 'HMS1792F07', 'HMS1990F07', 'HMS2250C03', 'HMS3229I16', 'HMS3261O08', 'HMS3267P06', 'HMS3295M01', 'HMS3403F07', 'HMS3412F05', 'HMS3654P10', 'HMS3676F05', 'HMS3747M19', 'PS653', 'ALBB-024051', 'Anthra[1,9cd]pyrazol-6(2H)-one', 'BCP05457', 'EX-A1998', 'Tox21_110267', 'Tox21_500473', 'BDBM50024294', 'BDBM50433916', 'CCG-47500', 'Dibenzo[cd,g]indazol-6(2H)-one #', 'HB2234', 'HSCI1_000136', 'NSC755773', 's1460', 'AKOS000115584', 'AKOS040751313', 'Anthrapyrazolone; 1,9-Pyrazoloanthrone', 'CCG-100672', 'CS-0196', 'DB01782', 'FP33726', 'LP00473', 'NSC-755773', 'SDCCGSBI-0050458.P003', 'SDCCGSBI-0050458.P009', 'WLN: T C66651A P IV OMNJ', '1,6-dihydrodibenzo[cd,g]indazol-6-one', '2,6-dihydrodibenzo[cd,g]indazol-6-one', 'IDI1_002128', 'QTL1_000077', 's10332', 'SMP2_000240', 'NCGC00015958-01', 'NCGC00015958-02', 'NCGC00015958-04', 'NCGC00015958-05', 'NCGC00015958-06', 'NCGC00015958-07', 'NCGC00015958-08', 'NCGC00015958-22', 'NCGC00025186-01', 'NCGC00025186-02', 'NCGC00025186-03', 'NCGC00025186-04', 'NCGC00025186-05', 'NCGC00261158-01', 'WLN: T C6665 1A P IV OMNJ', 'AC-32051', 'AS-14374', 'CAS-129-56-6', 'HY-12041', 'JNK Inhibitor II - CAS 129-56-6', 'SMR002530644', 'SY052909', 'DB-041928', 'SP600125?', 'A2548', 'EU-0100473', 'NS00020981', 'SW218106-2', 'EN300-02083', 'Anthra[1,9-cd]pyrazol-6(2H)-one & Z-100', 'K00068', 'S 5567', 'SP600125, >=98% (HPLC)', 'AB00075935-01', 'SP 600125 & Z-100', 'AE-641/00620033', 'Q4545713', 'SR-01000075840-1', 'SR-01000075840-2', 'SR-01000075840-4', 'SR-01000075840-6', 'SR-01000637108-1', 'BRD-K01567962-001-04-0', 'BRD-K01567962-001-06-5', 'BRD-K01567962-001-08-1', 'BRD-K01567962-001-22-2', 'BRD-K01567962-001-23-0', 'BRD-K01567962-001-24-8', 'Z56785477', 'F1414-1245', '14,15-diazatetracyclo[7.6.1.0;{2,7}.0;{13,16}]hexadeca-1(15),2(7),3,5,9(16),10,12-heptaen-8-one', '14,15-diazatetracyclo[7.6.1.0^{2,7}.0^{13,16}]hexadeca-1(15),2,4,6,9(16),10,12-heptaen-8-one']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"AZD6738","PubChemCID":"54761306","SMILES":"C[C@@H]1COCCN1C2=NC(=NC(=C2)C3(CC3)[S@](=N)(=O)C)C4=C5C=CNC5=NC=C4","Synonyms":"['AZD6738', 'Ceralasertib', '1352226-88-0', 'CHEMBL4285417', 'AZD 6738', 'BDBM50468001', 'MFCD29472273', 'imino-methyl-[1-[6-[(3R)-3-methylmorpholin-4-yl]-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl]cyclopropyl]-oxo-lambda6-sulfane', 'BDBM60432', 'OHUHVTCQTUDPIJ-JYCIKRDWSA-N', 'VJM', 'Ceralasertib (AZD6738)', 'Ceralasertib (JAN/USAN/INN)', 'GTPL9390', 'SCHEMBL9979340', 'EX-A1101', 'imino-methyl-[1-[6-[(3R)-3-methylmorpholin-4-yl]-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl]cyclopropyl]-oxo-|E6-sulfane', 'AZD-6738?', 'BDBM50585017', 'NSC780249', 'NSC800979', 's7693', 'AKOS032960475', 'CCG-268794', 'CS-5187', 'NSC-780249', 'NSC-800979', '(R)-imino(methyl)(1-(6-((R)-3-methylmorpholino)-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl)cyclopropyl)-l6-sulfanone', 'AC-32647', 'FA145496', 'HY-19323', 'D11787', 'Z3952965739', '(R)-3-methyl-4-(6-(1-((R)-S-methylsulfonimidoyl)cyclopropyl)-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl)morpholine', '(R)-imino(methyl)(1-{6-[(3R)-3-methylmorpholin-4-yl]-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl}cyclopropyl)-lambda6-sulfanone', '4-{4-[(3R)-3-Methylmorpholin-4-yl]-6-[1-((R)-S-methylsulfonimidoyl)cyclopropyl]pyrimidin-2-yl}-1H-pyrrolo[2,3-b]pyridine']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"NU7441","PubChemCID":"11327430","SMILES":"C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC5=C4SC6=CC=CC=C56","Synonyms":"['503468-95-9', 'NU7441', 'NU 7441', 'KU-57788', 'NU-7441', 'NU7441 (KU-57788)', '8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one', 'KU57788', '8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-one', '8-dibenzothiophen-4-yl-2-morpholin-4-ylchromen-4-one', 'XF6ZJD5WGU', 'NU-7432', 'KU 57788', '8-dibenzothiophen-4-yl-2-morpholin-4-yl-chromen-4-one', 'CHEMBL188678', '4H-1-Benzopyran-4-one, 8-(4-dibenzothienyl)-2-(4-morpholinyl)-', '8-(Dibenzo[b,D]thiophen-4-Yl)-2-(Morpholin-4-Yl)-4h-Chromen-4-One', '2R4', 'NU7441(KU-57788)', 'UNII-XF6ZJD5WGU', 'MLS006011188', 'SCHEMBL600096', 'GTPL8010', 'CHEBI:91361', 'DTXSID60462509', '4o72', 'GLXC-03693', 'HMS3265K11', 'HMS3265K12', 'HMS3265L11', 'HMS3265L12', 'HMS3656N07', 'HMS3748A17', 'BCP01954', 'EX-A1331', 'BDBM50156495', 's2638', 'AKOS024457766', 'BCP9000823', 'CCG-268806', 'CP-0073', 'SB19243', 'SDCCGSBI-0654435.P001', 'NCGC00250377-01', 'NU7441,KU-57788', 'AC-32075', 'HY-11006', 'KU-47788', 'SMR004702957', 'DB-071172', 'SW219708-1', 'NU-7441 (KU-57788)', 'NU-7441 (KU-57788)?', 'BRD-K00337317-001-01-7', 'BRD-K00337317-001-06-6', 'Q27088099', '8-dibenzothiophen-1-yl-2-morpholin-4-yl-chromen-4-one', '8-dibenzothiophene-4-yl-2-morpholin-4-yl-chromen-4-on', '8-(Dibenzo[b,d]thiophen-4-yl)-2-(morpholin-4-yl)-4H-1-benzopyran-4-one', '2-(MORPHOLIN-4-YL)-8-{8-THIATRICYCLO[7.4.0.0(2),?]TRIDECA-1(9),2(7),3,5,10,12-HEXAEN-6-YL}CHROMEN-4-ONE']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Ms","PubChemCID":"4448381","SMILES":"CSCCC(C(=O)NC(CO)C(=O)O)N","Synonyms":"['MS dipeptide', 'M-S Dipeptide', 'Methionine Serine dipeptide', 'Methionine-Serine dipeptide', 'SCHEMBL4284627', 'MS']","Type":"small molecule"},{"Action":"Not found","PerturbationName":"Epz","PubChemCID":"11006912","SMILES":"C[C@H](C(=O)O)O[C@@H]1[C@H]([C@H](O[C@@H]([C@H]1O)CO)OP(=O)(O)OP(=O)(O)OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC(=O)NC3=O)O)O)NC(=O)C","Synonyms":"['UDP-N-acetylmuramic acid', 'UDP-MurNAc', 'UDP-N-acetyl-alpha-D-muramic acid', '(2r)-2-{[(2r,3r,4r,5s,6r)-3-(Acetylamino)-2-{[(S)-{[(R)-{[(2r,3s,4r,5r)-5-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2h)-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl]methoxy}(Hydroxy)phosphoryl]oxy}(Hydroxy)phosphoryl]oxy}-5-Hydroxy-6-(Hydroxymethyl)tetrahydro-2h-Pyran-4-Yl]oxy}propanoic Acid', 'Acetylmuramic Acid, UDP', 'UDP-N-acetylmuramate', '(2R)-2-[(2R,3R,4R,5S,6R)-3-acetamido-2-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxypropanoic acid', '18867-75-9', \"uridine 5'-(3-{2-acetylamino-3-O-[(R)-1-carboxyethyl]-2-deoxy-alpha-D-glucopyranosyl} dihydrogen diphosphate)\", 'EPZ', 'UDP-N-acetylmuramicacid', 'CHEBI:70765', 'NQBRVZNDBBMBLJ-MQTLHLSBSA-N', 'C01050', 'Q27139075', '(2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2-{[(S)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoic acid (non-preferred name)']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Ponatinib","PubChemCID":"24826799","SMILES":"CC1=C(C=C(C=C1)C(=O)NC2=CC(=C(C=C2)CN3CCN(CC3)C)C(F)(F)F)C#CC4=CN=C5N4N=CC=C5","Synonyms":"['PONATINIB', '943319-70-8', '3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide', 'ponatinibum', 'UNII-4340891KFS', 'CHEBI:78543', 'HSDB 8184', '4340891KFS', 'DTXSID50241426', '3-(Imidazo[1,2-B]pyridazin-3-Ylethynyl)-4-Methyl-N-{4-[(4-Methylpiperazin-1-Yl)methyl]-3-(Trifluoromethyl)phenyl}benzamide', '3-(2-(IMIDAZO(1,2-B)PYRIDAZIN-3-YL)ETHYNYL)-4-METHYL-N-(4-((4-METHYLPIPERAZIN-1-YL)METHYL)-3-(TRIFLUOROMETHYL)PHENYL)BENZAMIDE', '3-(2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide', '3-(2-{imidazo[1,2-b]pyridazin-3-yl}ethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide', '3-(imidazo(1,2-b)pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide', '3-[2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-n-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide', 'DTXCID50163917', 'L01XE24', '3-(2-(imidazo(1,2-b)pyridazin-3-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-y-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide', 'Benzamide, 3-(2-Imidazo(1,2-B)Pyridazin-3-Ylethynyl)-4-Methyl-N-(4-((4-Methyl-1-Piperazinyl)Methyl)-3-(Trifluoromethyl)Phenyl)', 'BENZAMIDE, 3-(2-IMIDAZO(1,2-B)PYRIDAZIN-3-YLETHYNYL)-4-METHYL-N-(4-((4-METHYL-1-PIPERAZINYL)METHYL)-3-(TRIFLUOROMETHYL)PHENYL)-', 'AP24534', 'Ponatinib (AP24534)', 'AP 24534', 'AP-24534', '3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide', 'CHEMBL1171837', '943319-70-8 (free base)', '3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide', 'Benzamide, 3-(2-imidazo(1,2-b)pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methyl-1- piperazinyl)methyl)-3-(trifluoromethyl)phenyl)-', '3-(2-(Imidazo(1,2-b)pyridazin-3-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1- yl)methyl)-3-(trifluoromethyl)phenyl)benzamide', '3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide.', 'Ponatinib [USAN]', 'Ponatinib [USAN:INN]', '0LI', '3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide', 'Benzamide, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-; 3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide; AP 24534; Iclusig; Ponatinib', 'MFCD17215203', 'Ponatinib (Standard)', 'AP24534,Ponatinib', 'PONATINIB [INN]', 'PONATINIB [MI]', 'Ponatinib (USAN/INN)', 'PONATINIB [VANDF]', 'AP24534 (Ponatinib)', 'PONATINIB [WHO-DD]', 'Ponatinib (AP24534)?', 'MLS006010166', 'SCHEMBL589260', 'GTPL5890', 'EX-A067', 'BCPP000397', 'HMS3295I23', 'HMS3654H16', 'BCP02037', 'BDBM50322535', 'HY-12047R', 'NSC758487', 'NSC800855', 'AKOS015995214', 'BCP9000307', 'CCG-264900', 'CS-0204', 'DB08901', 'FP27104', 'NSC-758487', 'NSC-800855', 'PB34916', 'SDCCGSBI-0654374.P001', 'NCGC00263152-01', 'NCGC00263152-02', 'NCGC00263152-12', 'NCGC00263152-14', 'AC-26973', 'AS-19133', 'HY-12047', 'SMR004701274', 'NS00072196', 'S1490', 'SW218091-2', 'D09950', 'AB01565847_03', 'EN300-6733072', 'Q198728', 'BRD-K44227013-001-02-3', 'BRD-K44227013-001-06-4', 'BRD-K44227013-001-08-0', 'Z1828098700', '3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide;AP 2453 4', '3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"LY2584702","PubChemCID":"25118925","SMILES":"CN1C=C(N=C1C2CCN(CC2)C3=NC=NC4=C3C=NN4)C5=CC(=C(C=C5)F)C(F)(F)F","Synonyms":"['LY2584702', 'LY-2584702', '4-[4-[4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-methylimidazol-2-yl]piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine', 'UNII-I4965C6W4O', '1H-Pyrazolo(3,4-d)pyrimidine, 4-(4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazol-2-yl)-1-piperidinyl)-', '4-(4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1-methylimidazol-2-yl)piperidin-1-yl)-1H-pyrazolo(3,4-d)pyrimidine', '4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazol-2-yl)-1-(1H-pyrazolo(3,4-d)pyrimidin-4-yl)piperidine', '4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl}-1-{1H-pyrazolo[3,4-d]pyrimidin-4-yl}piperidine', 'p70S6K Inhibitor LY2584702', '4-(4-(4-(4-fluoro-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazol-2-yl)-1-piperidinyl)-1H-pyrazolo(3,4-d)pyrimidine', '1082949-67-4', 'LY 2584702', 'LY-2584702 free base', 'LY-2584702 (free base)', 'I4965C6W4O', '4-(4-(4-(4-Fluoro-3-(trifluoromethyl)phenyl)-1-methyl-1H-imidazol-2-yl)piperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine', 'SCHEMBL311369', 'GTPL8248', 'CHEMBL3545076', 'HMS3673E19', 'HMS3743I21', 'BCP14038', 'EX-A2213', 'BDBM50271976', 'NSC800787', 's7698', 'AKOS025404702', 'CCG-269181', 'CS-3596', 'DB12690', 'NSC-800787', 'NCGC00386428-01', 'NCGC00386428-05', 'NCGC00386428-06', 'AC-35412', 'DA-55103', 'FL103547', 'HY-12493', 'NS00072565', 'BRD-K21833260-075-01-1', 'BRD-K21833260-075-02-9', 'Q27082714', '4-{-4-[4-(4-Fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidin-1-yl}-1H-pyrazolo[3,4-d]pyrimidine', '4-{4-[4-(4-fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidin-1-yl}-1H-pyrazolo[3,4-d]pyrimidine', '4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-methylimidazol-2-yl}-1-{2H-pyrazolo[3,4-d]pyrimidin-4-yl}piperidine']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Momelotinib","PubChemCID":"25062766","SMILES":"C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N","Synonyms":"['MOMELOTINIB', 'Cyt387', '1056634-68-4', 'Cyt-387', 'N-(Cyanomethyl)-4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)benzamide', 'CYT 387', 'CYT 11387', 'Momelotinib [USAN]', 'CYT-11387', 'momelotinibum', 'N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]benzamide', 'GS-0387', 'Momelotinib [USAN:INN]', '6O01GMS00P', 'CHEMBL1078178', 'N-(Cyanomethyl)-4-(2-((4-morpholinophenyl)-amino)pyrimidin-4-yl)benzamide', 'CYT-0387', 'N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide', 'MOMELOTINIB [INN]', 'MOMELOTINIB [WHO-DD]', 'N-(cyanomethyl)-4-(2-{[4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)benzamide', 'CHEBI:91407', 'DTXSID801026049', 'N-(Cyanomethyl)-4-(2-((4-(morpholin-4-yl)phenyl)amino)pyrimidin-4-yl)benzamide', 'GS0387', 'LM-1149', 'N-(CYANOMETHYL)-4-(2-(4-MORPHOLINOANILINO)PYRIMIDIN-4-YL)BENZAMIDE', 'N-(cyanomethyl)-4-[2-[4-(4-morpholinyl)anilino]-4-pyrimidinyl]benzamide', 'N-(cyanomethyl)-4-{2-[4-(morpholin-4-yl)anilino]pyrimidin-4-yl}benzamide', 'N-(cyanomethyl)-4-(2-(4-(4-morpholinyl)anilino)-4-pyrimidinyl)benzamide', 'N-(cyanomethyl)-4-(2-(4-(morpholin-4-yl)anilino)pyrimidin-4-yl)benzamide', 'DTXCID30200399', 'N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide', 'Momelotinib (CYT387)', 'MFCD16038899', 'Ojjaara', 'Benzamide, N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)-', 'UNII-6O01GMS00P', 'Omjjara', 'benzamide, n-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-', 'C23H22N6O2', 'C87', 'Momelotinib (USAN/INN)', 'MLS006011154', 'GTPL7791', 'SCHEMBL2237234', 'EX-A260', 'ZVHNDZWQTBEVRY-UHFFFAOYSA-N', 'GLXC-03525', 'HMS3244K19', 'HMS3244K20', 'HMS3244L19', 'HMS3295I01', 'HMS3655D12', 'HMS3744C15', 'BCP02328', 'CYT11387', 'CYT387,CYT 11387', 'Momelotinib (CYT387,CYT-387)', 'BDBM50311017', 'NSC767598', 'NSC800800', 's2219', 'Momelotinib (CYT387,CYT-387)?', 'AKOS015904624', 'N-(cyanomethyl)-4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]benzamide', 'BCP9000570', 'CCG-264946', 'CS-0053', 'DB11763', 'FC41383', 'NSC-767598', 'NSC-800800', 'SB14602', 'SDCCGSBI-0654405.P001', 'NCGC00244257-01', 'NCGC00244257-08', 'AC-23162', 'AS-19389', 'HY-10961', 'SMR004702928', 'SY060668', 'NS00072547', 'SW219679-1', 'D10315', 'EN300-20694510', 'Momelotinib (LM1149; CYT387; CYT11387)', 'Q252602', 'BRD-K87737963-001-01-1', 'BRD-K87737963-001-06-0', 'BRD-K87737963-001-07-8', 'Z2235801913', 'N-(Cyanomethyl)-4-[2-[(4-morpholinophenyl)amino]-4-pyrimidinyl]benzamide', 'CYT 11387, Cyt-387, N-(Cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]benzamide', 'N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide; CYT 11387; Momelotinib']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"AZD8055","PubChemCID":"25262965","SMILES":"C[C@H]1COCCN1C2=NC(=NC3=C2C=CC(=N3)C4=CC(=C(C=C4)OC)CO)N5CCOC[C@@H]5C","Synonyms":"['AZD8055', '1009298-09-2', 'AZD-8055', 'AZD 8055', '970JJ37FPW', '[5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol', '(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol', 'AZ-12600000', 'CHEBI:91329', 'AZD 8055 [WHO-DD]', 'DTXSID001020704', '(5-{2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl}-2-methoxyphenyl)methanol', '[5-[2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol', '{5-[2,4-bis(3S)(3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl}methanol', '(5-(2,4-bis(3S)(3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol', '5-(2,4-Bis((3S)-3-methyl-4-morpholinyl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxybenzenemethanol', '5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol', 'DTXCID001493218', 'MTOR KINASE INHIBITOR AZD8055', '836-652-5', '(5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol', 'UNII-970JJ37FPW', 'Benzenemethanol, 5-[2,4-bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-', 'CHEMBL1801204', '(5-(2,4-Bis((S)-3-methylmorpholino)pyrido-[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol', '(5-(2,4-bis((3S)-3-methylmorpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol.', 'KVLFRAWTRWDEDF-IRXDYDNUSA-N', 'MFCD16660191', 'MLS006010169', 'SCHEMBL298416', 'GTPL7714', 'EX-A044', 'BCP02171', 'EX-A1549', 'BDBM50348452', 'NSC758871', 'NSC799351', 's1555', 'AKOS016009126', 'BCP9000367', 'CCG-264912', 'CS-0067', 'DB12774', 'FA18068', 'NSC-758871', 'NSC-799351', 'SDCCGSBI-0654384.P001', 'SS-4787', '[5-[2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-phenyl]methanol', 'AC-28424', 'HY-10422', 'SMR004701277', 'NS00072625', 'SW218287-2', 'BRD-K69932463-001-02-3', 'BRD-K69932463-001-10-6', 'Q27074792', '[5-[2,4-bis((3s)-3-methylmorpholin -4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol', '5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy benzenemethanol', '5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol;[5-[2,4-Bis((3S)-3-methylmorpholin-4-yl    )pyrido[2,3-d]pyrimidin-7-yl]- 2-methoxyphenyl]methanol']","Type":"small molecule"},{"Action":"cytotoxic","PerturbationName":"Doxorubicin","PubChemCID":"31703","SMILES":"C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)O","Synonyms":"['doxorubicin', '23214-92-8', 'Adriablastin', 'Doxorubicine', 'Doxorubicinum', 'Doxorubicina', '14-Hydroxydaunomycin', '14-Hydroxydaunorubicine', 'Adriamycin semiquinone', 'Doxorubicine [INN-French]', 'Doxorubicinum [INN-Latin]', 'Doxorubicina [INN-Spanish]', 'CCRIS 739', 'HSDB 3070', 'NCI-C01514', 'NDC 38242-874', 'EINECS 245-495-6', 'NSC 123127', 'CHEBI:28748', 'UNII-80168379AG', 'NSC-759155', 'Caelyx (liposomal doxorubicin)', '80168379AG', 'DTXSID8021480', '(1S,3S)-3-Glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl-(3-amino-2,3,6-tridesoxy-alpha-L-lyxo-hexopyranosid)', '(1S,3S)-3-glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside', '(8S,10S)-10-((3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione', '1,2,3,4,6,11-Hexahydro-4beta,5,12-trihydroxy-4-(hydroxyacetyl)-10-methoxy-6,11-dioxonaphthacen-1beta-yl-3-amino-2,3,6-trideoxy-alpha-L-lyxohexopyranoside', '5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-', 'Doxorubicine (INN-French)', 'Doxorubicinum (INN-Latin)', 'Doxorubicina (INN-Spanish)', 'DOXORUBICIN (MART.)', 'DOXORUBICIN [MART.]', '(1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside', '(8S-cis)-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione', 'hydroxydaunomycin', '5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-', 'VALRUBICIN IMPURITY, DOXORUBICIN (USP IMPURITY)', 'VALRUBICIN IMPURITY, DOXORUBICIN [USP IMPURITY]', 'doxorrubicina', 'ADR', 'Hydroxyldaunorubicin', 'Hydroxyl Daunorubicin', '(8S-cis)-10-', 'DTXCID301480', 'L01DB01', '(8S,10S)-10', '(8S,10S)-10-', '(8S-cis)-10-((3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroacetyl)-1-methoxy-5,12-naphthacenedione', '1,2,3,4,6,11-hexahydro-4beta,5,12-trihydroxy-4-(hydroxyacetyl)-10-methoxy-6, 11-Dioxonaphthacen-1beta-yl-3-amino-2,3,6-trideoxy-alpha-l-lyxohexopyranoside', '245-495-6', '5,12-naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione', 'Adriamycin', 'Doxil', 'Adriblastina', 'Hydroxydaunorubicin', '(7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione', 'CHEMBL53463', 'ADM', 'NSC-123127', '(8S,10S)-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione', '(8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione', '5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-', 'Doxorubicin [USAN:INN:BAN]', 'ThermoDox', 'MLS000028393', 'Doxorubicin-hLL1', '(1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside', '(7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione', 'Adriblastina (TN)', 'Doxorubicin-P4/D10', 'Doxorubicin (USAN/INN)', 'Doxorubicin-hLL1 conjugate', 'Doxorubicin-P4/D10 conjugate', 'Doxorubicin?', 'DOXORUBICIN [MI]', 'Prestwick0_000438', 'Prestwick1_000438', 'Prestwick2_000438', 'Prestwick3_000438', 'DOXORUBICIN [INN]', 'DOXORUBICIN [HSDB]', 'DOXORUBICIN [USAN]', 'Probes1_000151', 'Probes2_000129', 'DOXORUBICIN [VANDF]', 'SCHEMBL3243', 'BSPBio_000456', 'BSPBio_001031', 'DOXORUBICIN [WHO-DD]', '10-((3-Amino-2,3,6-trideoxy-D-lyxohexopyranosyl)oxy)-8-glycolcyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione', 'SPBio_002395', 'BPBio1_000502', 'cid_443939', 'GTPL7069', 'Valrubicin impurity, doxorubicin', 'BDBM22984', 'BDBM32022', 'HMS2089H06', '(8S,10S)-10-((3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-LYXO-HEXOPYRANOSYL)OXY)-8-GLYCOLOYL-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-1-METHOXY-5,12-NAPHTHACENEDIONE', '5,12-NAPHTHACENEDIONE, 10-((3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-LYXO-HEXOPYRANOSYL)OXY)-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-8-(HYDROXYACETYL)-1-METHOXY-, (8S-CIS)-', 'GR-319', 'HY-15142A', 'LMPK13050001', 'AKOS015951330', 'Conjugate of doxorubicin with humanized monoclonal antibody LL1 against CD74', 'Conjugate of doxorubicin with monoclonal antibody P4/D10 against GP120', 'DB00997', 'SMP1_000106', 'NCGC00024415-35', 'NCGC00024415-37', 'NCGC00024415-38', 'NCGC00024415-40', 'NCGC00024415-41', 'NCGC00024415-42', 'NCGC00024415-61', 'AC-37453', 'BP-23114', 'NS00002473', 'C01661', 'D03899', 'EN300-120698', 'Epirubicin hydrochloride impurity, doxorubicin-', 'H11954', 'Q18936', 'BRD-K92093830-003-04-3', 'BRD-K92093830-003-25-8', 'BRD-K92093830-003-30-8', 'BRD-K92093830-003-31-6', 'BRD-K92093830-003-33-2', 'EPIRUBICIN HYDROCHLORIDE IMPURITY C [EP IMPURITY]', 'DAUNORUBICIN HYDROCHLORIDE IMPURITY D [EP IMPURITY]', 'EPIRUBICIN HYDROCHLORIDE IMPURITY, DOXORUBICIN- [USP IMPURITY]', '(7S,9R)-7-[(2S,4S,5S,6S)-4-Amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione', '(7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-9-glycoloyl-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-quinone;hydrochloride', '(7S,9S)-7-[(2R,4S,5S,6S)-4-azanyl-6-methyl-5-oxidanyl-oxan-2-yl]oxy-4-methoxy-6,9,11-tris(oxidanyl)-9-(2-oxidanylethanoyl)-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride', '(7S,9S)-7-[(4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione', '(7S,9S)-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride', '(8S-cis)-10-[(3-Amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione', '1392315-46-6', '5,12-naphthacenedione, 10-((3-Amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro- 6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione', '5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-|A-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Vandetanib","PubChemCID":"3081361","SMILES":"CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC","Synonyms":"['Vandetanib', '443913-73-3', 'N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine', 'N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine', 'GNF-PF-2188', 'ZD-64', 'NSC-744325', 'NSC-760766', 'CHEBI:49960', 'UNII-YO460OQ37K', 'YO460OQ37K', 'DTXSID1046681', 'HSDB 8198', 'N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-4-quinazolinamine', 'DTXCID9026681', 'N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine', 'NSC 744325', 'NSC 760766', 'VANDETANIB (MART.)', 'VANDETANIB [MART.]', '4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline', '4-Quninazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-', '4-BROMO-2-FLUORO-N-[(4E)-6-METHOXY-7-[(1-METHYLPIPERIDIN-4-YL)METHOXY]QUINAZOLIN-4(1H)-YLIDENE]ANILINE', 'vandetanibum', '4-BROMO-2-FLUORO-N-((4E)-6-METHOXY-7-((1-METHYLPIPERIDIN-4-YL)METHOXY)QUINAZOLIN-4(1H)-YLIDENE)ANILINE', 'AZD6474', 'L01XE12', '4-QUINAZOLINAMINE, N-(4-BROMO-2-FLUOROPHENYL)-6-METHOXY-7-((1-METHYL-4-PIPERIDINYL)METHOXY)-', 'Zactima', 'ZD6474', 'Caprelsa', 'ZD-6474', 'vandetanib (zd6474)', 'ZD 6474', '338992-00-0', 'AZD-6474', 'MFCD07772346', 'CHEMBL24828', 'Vandetanib [INN]', 'NCGC00167513-01', 'C22H24BrFN4O2', 'CAS-443913-73-3', '2ivu', 'Vandetanib [USAN:INN:BAN:JAN]', 'Caprelsa (TN)', 'CH 331', 'CH-331', 'Vandetanib (Zactima)', 'Vandetanib (Standard)', 'Kinome_3316', 'VANDETANIB [MI]', 'VANDETANIB [JAN]', 'VANDETANIB [USAN]', 'VANDETANIB [VANDF]', 'BDBM21', 'Vandetanib (ZD6474)?', 'SCHEMBL9044', 'VANDETANIB [WHO-DD]', 'MLS006011672', 'Vandetanib (JAN/USAN/INN)', 'F9995-0087', 'GTPL5717', 'Vandetanib - Bio-X trade mark', 'SCHEMBL21067679', 'VANDETANIB [ORANGE BOOK]', 'cid_3081361', 'EX-A422', 'UHTHHESEBZOYNR-UHFFFAOYSA-N', 'BCPP000023', 'HMS3244K03', 'HMS3244K04', 'HMS3244L03', 'HMS3654E11', 'HMS3672C07', 'BCP01925', 'ZWB68349', 'Tox21_112511', '443913-73-3 (free base)', 'BDBM50595124', 'HY-10260R', 'NSC744325', 'NSC760766', 'NSC800961', 's1046', 'AKOS015902350', 'Tox21_112511_1', 'AC-5251', 'CCG-269495', 'CS-0130', 'DB05294', 'FV28668', 'NSC-800961', 'SB16919', 'SDCCGSBI-0647658.P002', 'N-(4-bromo-2-fluoro-phenyl)-6-methoxy-7-[(1-methyl-4-piperidyl)methoxy]quinazolin-4-amine', 'NCGC00167513-02', 'NCGC00167513-03', 'NCGC00167513-04', 'NCGC00167513-09', '(4-Bromo-2-fluoro-phenyl)-[6-methoxy-7-(1-methyl-piperidin-4-ylmethoxy)-quinazolin-4-yl]-amine', 'AS-11067', 'BV164508', 'HY-10260', 'SMR002530472', 'SY027438', 'NS00008846', 'SW218092-2', 'D06407', 'EN300-265835', 'SBI-0647658.0001', 'V-9402', 'AB01273969-01', 'AB01273969-02', 'AB01273969_04', 'SR-00000000462', 'Q7914515', 'SR-00000000462-2', 'BRD-K77625799-001-01-0', 'BRD-K77625799-001-07-7', 'Z2512943095', '4-[(4-Bromo-2-fluorophenyl)amino]-6-methoxy-7-[(1-methyl-4-piperidyl)methoxy]quinazoline', '4-QUINAZOLINAMINE, N-(4-BROMO-2-FLUOROPHENYL)-6-METHOXY-7-((1-METHYL-4- PIPERIDINYL)METHOXY)-', 'N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine;4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[    (1-methylpiperidin-4-yl)methoxy]quinazoline;ZD 6474', 'N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine;4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[ (1-methylpiperidin-4-yl)methoxy]quinazoline;ZD 6474', 'Quinazolin-4-amine, N-(4-bromo-2-fluorophenyl)-6-mthoxy-7-[(1-methyl-4-piperidinyl)methoxy]-', 'ZD6']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Vemurafenib","PubChemCID":"42611257","SMILES":"CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)C4=CC=C(C=C4)Cl)F","Synonyms":"['Vemurafenib', '918504-65-1', 'PLX-4032', 'N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide', 'RO 5185426', 'vemurafenibum', 'N-(3-{[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide', 'UNII-207SMY3FQT', '207SMY3FQT', 'N-[3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]propane-1-sulfonamide', 'Ro 51-85426', 'CHEBI:63637', 'HSDB 8143', 'RO-5185426', 'RO-51-85426', 'DTXSID50238710', 'VEMURAFENIB (MART.)', 'VEMURAFENIB [MART.]', 'N-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide', 'N-(3-((5-(4-chlorophenyl)-1H-pyrrolo(2,3-b)pyridin-3-yl)carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide', 'N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo(2,3-b)pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide', 'Propane-1-sulfonic acid (3-', 'DTXCID00161201', 'L01XE15', '1-Propanesulfonamide, N-(3-((5-(4-chlorophenyl)-1H-pyrrolo(2,3-b)pyridin-3-yl)carbonyl)-2,4-difluorophenyl)-', 'BRAF(V600E) Kinase Inhibitor RO5185426', 'BRAF (V600E) kinase inhibitor RO5185426', 'PLX4032', 'Zelboraf', '1029872-54-5', 'PLX 4032', 'RG7204', 'RG 7204', 'Vemurafenib (PLX4032, RG7204)', 'RG-7204', 'RO5185426', 'Vemurafenib (PLX4032)', 'MFCD18074504', 'NSC761431', 'N-(3-((5-(4-Chlorophenyl)-1H-pyrrolo(2,3-b)pyridin-3-yl)carbonyl)-2,4- difluorophenyl)propane-1-sulfonamide', 'Vemurafenib;PLX-4032', '1-Propanesulfonamide, N-(3-((5-(4-chlorophenyl)-1H-pyrrolo(2,3-b)pyridin-3- yl)carbonyl)-2,4-difluorophenyl)-', 'Zelboraf (TN)', 'Vemurafenib [USAN]', 'Vemurafenib [USAN:INN]', 'C23H18ClF2N3O3S', 'N-(3-{(5-(4-chlorophenyl)-1H-pyrrolo(2,3-b)pyridin-3-yl)carbonyl}-2,4- difluorophenyl)propane-1-sulfonamide', 'Vemurafenib (Standard)', '3og7', 'VEMURAFENIB [MI]', '1415041-85-8', 'Vemurafenib; PLX4032', 'VEMURAFENIB [INN]', 'VEMURAFENIB [JAN]', 'VEMURAFENIB [VANDF]', 'Vemurafenib (PLX4032)?', 'VEMURAFENIB [WHO-DD]', 'N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-PropanesulfonaMide', 'SCHEMBL298931', 'Vemurafenib (JAN/USAN/INN)', 'GTPL5893', 'CHEMBL1229517', 'EX-A053', 'VEMURAFENIB [ORANGE BOOK]', 'GPXBXXGIAQBQNI-UHFFFAOYSA-N', 'HMS3265M03', 'HMS3265M04', 'HMS3265N03', 'HMS3265N04', 'HMS3654P09', 'HMS3748G15', 'BCP25783', 'EX-A1335', 'BDBM50396483', 'HB4285', 'HY-12057R', 'NSC800964', 's1267', 'AKOS007930804', 'CCG-264883', 'CS-0216', 'DB08881', 'FV15248', 'ME-0096', 'NSC-761431', 'NSC-800964', 'PB11741', 'SDCCGSBI-0647659.P002', 'NCGC00250399-01', 'NCGC00250399-05', 'NCGC00250399-08', 'AC-25010', 'HY-12057', 'N-[3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl]propane-1-sulfonamide', 'SY067868', 'NS00008103', 'SW218095-2', 'D09996', 'R-7204', 'AB01273970-01', 'AB01273970_03', 'EN300-23265091', 'Q423111', 'SR-01000941568', 'carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide', 'SR-01000941568-1', 'BRD-K56343971-001-02-3', 'BRD-K56343971-001-05-6', 'BRD-K56343971-001-10-6', 'BRD-K56343971-001-12-2', 'BRD-K56343971-001-14-8', 'PLX4032,Vemurafenib, RG7204, RO5185426, Zelboraf', 'N-{3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-', '1-Propanesulfonamide, N-(3-((5-(4-chlorophenyl)-1H- pyrrolo(2,3-b)pyridin-3- yl)carbonyl)-2,4-difluorophenyl)-', 'N-(3-(5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)-propane-1-sulfonamide', 'propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1h-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide', 'Vemurafenib;N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Gefitinib","PubChemCID":"123631","SMILES":"COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4","Synonyms":"['Gefitinib', '184475-35-2', 'Irressat', 'ZD-1839', 'gefitinibum', 'CCRIS 9011', 'UNII-S65743JHBS', 'NSC-759856', 'S65743JHBS', 'DTXSID8041034', 'CHEBI:49668', 'DTXCID6021034', 'NSC715055', 'NSC 759856', 'GEFITINIB (MART.)', 'GEFITINIB [MART.]', 'GEFITINIB (EP MONOGRAPH)', 'GEFITINIB [EP MONOGRAPH]', 'L01XE02', 'Iressa', 'ZD1839', 'N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine', 'gefitinib (zd1839)', 'ZD 1839', 'N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine', 'Gefitinib (GMP)', 'MFCD04307832', 'N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine', 'N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine', 'N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine', \"4-(3'-Chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline\", 'CHEMBL939', 'Gefitinib [USAN]', 'NCGC00159455-02', '3-Chloro-4-Fluoro-N-[(4z)-7-Methoxy-6-(3-Morpholin-4-Ylpropoxy)quinazolin-4(1h)-Ylidene]aniline', 'C22H24ClFN4O3', 'Iressa(TM)', 'IRE', 'Iressa (TN)', 'CAS-184475-35-2', 'SR-00000000262', 'Gefitinib [USAN:INN:BAN]', 'Gefitini; Iressa', 'N-(3-Chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4 -ylpropoxy)quinazolin-4-amine', 'N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine', 'Gefitinib (Standard)', 'Iressa (AstraZeneca)', 'nchembio866-comp14', 'Kinome_3321', 'Kinome_3322', 'GEFITINIB [INN]', 'GEFITINIB [JAN]', 'GEFITINIB [MI]', 'GEFITINIB [VANDF]', 'Gefitinib (ZD1839)?', 'GEFITINIB [WHO-DD]', 'SCHEMBL7866', 'Gefitinib,ZD-1839,Iressa', 'GEFITINIB [EMA EPAR]', 'KBioSS_002241', 'MLS003899193', 'CU-00000000396-1', 'Gefitinib - Bio-X trade mark', 'BDBM5447', 'cid_123631', 'GTPL4941', 'Gefitinib (JP18/USAN/INN)', 'GEFITINIB [ORANGE BOOK]', 'Gefitinib, >=98% (HPLC)', 'BCPP000221', 'GLXC-05820', 'HMS2089B19', 'HMS3244M21', 'HMS3244M22', 'HMS3244N21', 'HMS3295A21', 'HMS3413H08', 'HMS3654A07', 'HMS3677H08', 'HMS3714A05', 'HMS3748E17', 'Pharmakon1600-01502274', 'BCP01365', 'YWB97640', 'Tox21_111683', 'HY-50895G', 'HY-50895R', 'NSC759856', 'NSC800105', 's1025', 'STK621310', 'AKOS000280752', 'Tox21_111683_1', 'AB20814', 'AC-1556', 'BCP9000718', 'CCG-220642', 'CS-0124', 'DB00317', 'FG10816', 'KS-1204', 'NSC-715055', 'NSC-800105', 'SDCCGSBI-0634411.P005', '4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-(3-morpholinopropoxy)quinazoline', '4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-4-morpholin)propoxy)-', '6-(3-morpholinopropoxy)-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazolin-4-amine', 'N-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine', 'NCGC00159455-03', 'NCGC00159455-04', 'NCGC00159455-05', 'NCGC00159455-06', 'NCGC00159455-08', 'NCGC00159455-09', 'NCGC00159455-14', 'BCB03_000781', 'BG164498', 'HY-50895', 'SMR002204119', 'SY002154', 'CS-0622782', 'G0546', 'NS00006312', 'SW199108-4', 'D01977', 'EN300-123024', 'G-4408', 'K00240', 'AB01273954-01', 'AB01273954-02', 'AB01273954-03', 'AB01273954_04', 'Q417824', 'SR-00000000262-2', 'SR-00000000262-3', 'BRD-K64052750-001-16-7', 'BRD-K64052750-001-17-5', 'BRD-K64052750-001-22-5', 'BRD-K64052750-001-23-3', 'Gefitinib, EuropePharmacopoeia (EP) Reference Standard', 'Z1546610485', \"4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)-quinazoline\", 'Gefitinib for system suitability, EuropePharmacopoeia (EP) Reference Standard', '(3-CHLORO-4-FLUORO-PHENYL)-[7-METHOXY-6-(3-MORPHOLIN-4-YL-PROPOXY)-QUINAZOLIN-4-YL]-AMINE']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Dexamethasone","PubChemCID":"5743","SMILES":"C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C","Synonyms":"['dexamethasone', '50-02-2', 'Hexadecadrol', 'Aeroseb-Dex', 'Fluormethylprednisolone', 'Desametasone', 'Superprednol', 'Visumetazone', 'Cortisumman', 'Decaderm', 'Dexacortal', 'Dexacortin', 'Gammacorten', 'Auxiron', 'Calonat', 'Dexason', 'Dexone', 'Dectancyl', 'Deltafluorene', 'Desamethasone', 'Desameton', 'Mediamethasone', 'Mymethasone', 'Decalix', 'Dekacort', 'Dexameth', 'Dinormon', 'Loverine', 'Luxazone', 'Dexa-Scheroson', 'Dexa-sine', 'Isopto-Dex', 'Aeroseb-D', 'Anaflogistico', 'Decacortin', 'Deseronil', 'Dexafarma', 'Dexinolon', 'Dexinoral', 'Policort', 'Spoloven', 'Deronil', 'Dexapos', 'Sunia Sol D', 'Bisu DS', 'Dexa Mamallet', 'Lokalison F', 'Ocu-trol', 'Dex-ide', 'Dexamethasonum', 'Dexametasona', 'Fluormone', 'Dexone 4', 'Pet Derm III', 'Dexamethasone Intensol', 'Methylfluorprednisolone', 'Dexone 0.5', 'Dexone 1.5', 'Dexone 0.75', 'Decacort', 'Dexamonozon', 'Dextenza', '9alpha-Fluoro-16alpha-methylprednisolone', 'Dexametasona [INN-Spanish]', 'Dexamethasonum [INN-Latin]', 'Dexametasone', 'Adexone', 'Osurdex', 'Dexycu', 'DexaSite', '16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol', '16alpha-Methyl-9alpha-fluoroprednisolone', 'delta1-9alpha-Fluoro-16alpha-methylcortisol', 'NSC 34521', '1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone', 'CCRIS 7067', 'Diodex', 'DTXSID3020384', 'HSDB 3053', 'ISV-305', 'Zema-Pak', 'UNII-7S5I7G3JQL', '16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone', 'EINECS 200-003-9', '7S5I7G3JQL', 'NSC-34521', '16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone', 'DXM [Steroid]', '16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone', 'HEMADY', 'Dexamethasone, topical', 'CHEBI:41879', 'AI3-50934', 'Prednisolone, 9alpha-fluoro-16alpha-methyl-', 'DTXCID10384', 'Dexamethasone [USP:INN:BAN:JAN]', 'DXM (Steroid)', 'CIPRODEX COMPONENT DEXAMETHASONE', 'MAXITROL COMPONENT DEXAMETHASONE', 'TOBRADEX COMPONENT DEXAMETHASONE', 'DEXACIDIN COMPONENT DEXAMETHASONE', 'DEXASPORIN COMPONENT DEXAMETHASONE', 'TOBRADEX ST COMPONENT DEXAMETHASONE', 'Dexa-Mamallet', 'Dexametasona (INN-Spanish)', 'Dexamethasonum (INN-Latin)', 'DEXAMETHASONE (MART.)', 'DEXAMETHASONE [MART.]', 'DEXAMETHASONE (USP-RS)', 'DEXAMETHASONE [USP-RS]', 'Dexamethasone (USP:INN:BAN:JAN)', 'DEXAMETHASONE (EP MONOGRAPH)', 'DEXAMETHASONE [EP MONOGRAPH]', 'DEXAMETHASONE (USP MONOGRAPH)', 'DEXAMETHASONE [USP MONOGRAPH]', 'BETAMETHASONE IMPURITY A (EP IMPURITY)', 'BETAMETHASONE IMPURITY A [EP IMPURITY]', 'alin', 'Amplidermis', 'Cortidexason', 'Dexafluorene', 'Dexamecortin', 'Dexamethsone', 'Fluorodelta', 'Aacidexam', 'Baycadron', 'Decadrol', 'Dexabliss', 'Dexachel', 'Dexalocal', 'Dexasine', 'Spersadex', 'Dxevo', 'TaperDex', 'Aknichthol Dexa', 'Alin Oftalmico', 'Anemul mono', 'Azium Solution', 'Dexium Tablets', 'Azium Powder', 'Dexa-Rhinosan', 'ZoDex', 'Alin Depot', 'Baycuten N', 'Lokalison-F', 'Decadron DP', 'Alba-Dex', 'Zonometh Solution', 'Dexameth-A-Vet', 'TaperDex 6-day', 'TaperDex 7-day', 'Decasone R.p.', 'TaperDex 12-day', 'HiDex 6-day', 'Dexamethasone1.5 mg', 'Dexamethasone Solution', 'Dexamethasone Injection', 'DEXYCU KIT', 'Azium Boluses 10 mg', 'Dexamethasone 1.5 mg', 'Pet Derm III Tablets', 'Dexameth-A-Vet Injection', 'Azium Tablets 0.25 mg', 'DEXAMETHASONE 6-Day', 'Azium Oral Solution 2 mg', 'Dexamethasone Sterile Solution', 'Azium Aqueous Suspension Veterinary', 'DEXAMETHASONE COMPONENT OF CIPRODEX', 'DEXAMETHASONE COMPONENT OF MAXITROL', 'DEXAMETHASONE COMPONENT OF TOBRADEX', 'DEXAMETHASONE COMPONENT OF DEXACIDIN', 'Fluoro-9alpha Methyl-16alpha Prednisolone', 'DEXAMETHASONE COMPONENT OF DEXASPORIN', 'DEXAMETHASONE COMPONENT OF TOBRADEX ST', '16Alpha-methyl-9alpha-fluoro-delta1-hydrocortisone', '1-Dehydro-16alpha-methyl-0alpha-fluorohydrocortisone', 'delta(Sup1)-9-alpha-fluoro-16-alpha-methylcortisol', '200-003-9', 'auxiloson', 'Decadron', 'Maxidex', 'Dexamethazone', 'Dexasone', 'Hexadrol', 'Decaspray', 'Millicorten', 'Oradexon', 'Prednisolone F', 'Fortecortin', 'Dexacort', 'Azium', 'Aphtasolon', 'Decasone', 'Dergramin', 'Desadrene', 'Dexadeltone', 'Dexalona', 'Dexapolcort', 'Dextelan', 'Corsone', 'Mexidex', 'Dexa-Cortidelt', 'Dexa-Cortisyl', 'Prednisolon F', 'SK-Dexamethasone', 'Dexaprol', 'Decagel', 'Hexadrol Elixir', 'Hl-dex', 'Fluorocort', 'Decaject', 'Decameth', 'Dexpak', 'Dxms', 'Dexamethasone alcohol', 'Hexadrol Tablets', 'Desametasone [DCIT]', 'Turbinaire', 'Ozurdex', 'Dezone', 'Decadron Tablets, Elixir', 'Azium (Veterinary)', 'Dexamethansone', 'Posurdex', 'OTO-104', 'Corson', 'Dexamethasone Base', '(3H)-Dexamethasone', 'Azimycin (Veterinary)', 'MFCD00064136', 'MK 125', '(11beta,16alpha)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione', 'Naquasone (Veterinary)', 'Tresaderm (Veterinary)', '16-alpha-Methyl-9-alpha-fluoroprednisolone', '9-alpha-Fluoro-16-alpha-methylprednisolone', '16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol', 'Dexamethasone (GMP)', 'delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol', '9A-FLUORO-16BETA-METHYLPREDNISOLONE', 'MLS001332507', '(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one', '16.alpha.-Methyl-9.alpha.-fluoroprednisolone', '9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione', '[3H]-dexamethasone', 'DEXA', '[3H]dexamethasone', 'Aphthasolone', '9.alpha.-Fluoro-16.alpha.-methylprednisolone', '(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one', '16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol', '1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone', 'Decadron (TN)', '(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one', 'SMR000857119', 'dexamethasone (tetramethyl-rhodamine conjugated )', 'Prednisolone, 9.alpha.-fluoro-16.alpha.-methyl-', '.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol', '16.alpha.-Methyl-9.alpha.-fluoro-.delta.(sup1)-hydrocortisone', 'NSC34521', '.gamma.corten', 'Apo-dexamethasone', 'Dexasone 4mg', 'PHL-dexamethasone', 'PMS-dexamethasone', 'Dexamethasone-omega', 'NCGC00091019-08', 'Dexasone 0.5mg', 'Dexasone 0.75mg', 'Sandoz Dexamethasone', 'Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11beta,16alpha)-', 'Maxidex Ont 0.1%', 'Maxidex Sus 0.1%', 'Dexamethasone (Standard)', 'Spectrum5_002019', 'DEXAMETHASONE [MI]', 'MolMap_000018', '(9R,14S)-Dexamethasone', 'DEXAMETHASONE [INN]', 'DEXAMETHASONE [JAN]', 'SCHEMBL3774', '16-alpha-Methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione', '16-alpha-Methyl-9-alpha-fluoro-11-beta,17-alpha,21-trihydroxypregna-1,4-diene-3,20-dione', '4-alpha-Fluoro-16-alpha-methyl-11-beta,17,21-trihydroxypregna-1,4-diene-3,20-dione', '9-alpha-Fluoro-16-alpha-methyl-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione', 'DEXAMETHASONE [HSDB]', 'BIDD:PXR0060', 'BSPBio_000995', 'DEXAMETHASONE [VANDF]', 'MLS001055412', 'MLS001332508', 'BIDD:ER0494', 'sustained-release dexamethasone', 'DEXAMETHASONE [WHO-DD]', 'DEXAMETHASONE [WHO-IP]', 'CHEMBL384467', 'GTPL2768', 'GTPL3447', 'SGCUT00126', '9-Fluoro-16-methylprednisolone', 'Ak Dex Oph Otic Soln 0.1%', 'DEXAMETHASONE [EMA EPAR]', 'BDBM18207', 'Dexamethasone (anti-inflammatory)', 'Dexamethasone (JP18/USP/INN)', 'MSK2218', '1p93', 'DEXAMETHASONE [GREEN BOOK]', 'GLXC-06963', 'HMS1792A17', 'HMS1990A17', 'HMS2089N13', 'HMS2235F08', 'HMS3039L11', 'HMS3259N11', 'HMS3403A17', 'DEXAMETHASONE [ORANGE BOOK]', 'to_000038', 'Tox21_200122', 'Dexamethasone, >=97.0% (HPLC)', 'HB2521', 'HY-14648G', 'HY-14648R', 'IBI-10090', 'MK-125', 's1322', 'Dexamethasone 1.0 mg/ml in Methanol', 'DEXAMETHASONUM [WHO-IP LATIN]', 'PMS Dexamethasone Elixir 0.5mg/5ml', 'AKOS005259009', 'AKOS015895509', 'CCG-264887', 'CS-1505', 'DB01234', 'FD15640', 'KS-1451', 'NC00645', 'US10869929, Compound Dexamethasone', 'US11554172, Compound Dexamethasone', 'alpha -Fluoro-16-alpha -methylcortisol', 'CAS-50-02-2', 'Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-', 'SMP1_000092', 'Dexamethasone, >=98% (HPLC), powder', 'NCGC00091019-01', 'NCGC00091019-02', 'NCGC00091019-03', 'NCGC00091019-04', 'NCGC00091019-05', 'NCGC00091019-06', 'NCGC00091019-07', 'NCGC00091019-23', 'NCGC00257676-01', '(11beta,16alpha)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione labeled with tritium', '(8S,9R,10S,11S,13S,14S,16R,17R)-9-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]ph', '23495-06-9', '9alpha-fluoro-16alpha-methyl-Prednisolone', 'AC-11056', 'HY-14648', 'NCI60_003067', 'Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, labeled with tritium, (11beta,16alpha)-', 'SMR001227192', '16alpha -Methyl-9alpha -fluoroprednisolone', '9alpha -Fluoro-16alpha -methylprednisolone', 'Dexamethasone, tested according to Ph.Eur.', 'CS-0626118', 'NS00000344', 'EN300-52607', 'D00292', 'Dexamethasone, meets USP testing specifications', 'Prednisolone, 9alpha -fluoro-16alpha -methyl-', '9.alpha.-Fluoro-16.alpha.-methyl-1,20-dione', 'AB00918428-05', 'AB00918428-08', 'AB00918428-09', 'AB00918428_10', '16alpha -Methyl-9alpha -fluoro-1-dehydrocortisol', 'Dexamethasone, VETRANAL(TM), analytical standard', 'Q422252', 'BRD-K38775274-001-02-3', 'BRD-K38775274-001-06-4', 'DEXAMETHASONE ACETATE IMPURITY A [EP IMPURITY]', '1-Dehydro-16alpha -methyl-9alpha -fluorohydrocortisone', '9-Fluoro-11alpha -methylpregna-1,4-diene-3,20-dione', 'Dexamethasone, British Pharmacopoeia (BP) Assay Standard', 'Z756391748', 'Pregna-1,4-diene-3,20-dione, 9-fluoro-11alpha -methyl-', 'Dexamethasone, European Pharmacopoeia (EP) Reference Standard', 'WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1', 'Dexamethasone, powder, BioReagent, suitable for cell culture, >=97%', 'Dexamethasone, United States Pharmacopeia (USP) Reference Standard', '16-.alpha.-Methyl-9-.alpha.-fluoro-1,17-.alpha.,21-triol-3,20-dione', '4.alpha.-Fluoro-16.alpha.-methyl-11.beta.-17,4-diene-3,20-dione', 'Pregna-1,20-dione, 9-fluoro-11.beta.,17,21-trihydroxy-16.alpha.-methyl-', '16.alpha.-Methyl-9.alpha.-fluoro-11.beta.-17.alpha.-21-trihydroxypregna-1,20-dione', '9-Fluoro-11.beta.,21-trihydroxy-16.alpha.-methylpregna-1,4-diene-3,20-dione', '9-fluoro-16alpha-methyl-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione', '9.alpha.-Fluoro-11.beta.-17.alpha.- 21-trihydroxy-16.alpha.-methylpregna-1,20-dione', '9alpha-Fluoro-16alpha-methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione', 'Dexamethasone for peak identification, European Pharmacopoeia (EP) Reference Standard', 'Dexamethasone for system suitability, European Pharmacopoeia (EP) Reference Standard', 'Dexamethasone, Pharmaceutical Secondary Standard; Certified Reference Material', 'Dexamethasone, powder, gamma-irradiated, BioXtra, suitable for cell culture, >=80% (HPLC)', 'Pregna-1,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11.beta.,16.alpha.)-', '(11.BETA.,16.ALPHA.)-9-FLUORO-11,17,21-TRIHYDROXY-16-METHYLPREGNA-1,4-DIENE-3,20-DIONE', '(11alpha,14beta,16alpha,17alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione', '(1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one', '1050677-47-8', '9.alpha.-Fluoro-16.alpha.-methyl-11.beta.,21.beta.-trihydroxy-pregna-1,4-diene-3,20-dione', 'Prednisolone F; 9alpha-Fluoro-16alpha-methylprednisolone; (11beta,16alpha)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,', 'PREGNA-1,4-DIENE-3,20-DIONE, 9-FLUORO-11,17,21-TRIHYDROXY-16-METHYL-,(11.BETA.,16.ALPHA.)-9-FLUORO-11.BETA.,17,21-TRIHYDROXY-16.ALPHA.-METHYLPREGNA-1,4-DIENE-3,20-DIONE']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Gsk525762a","PubChemCID":"46943432","SMILES":"CCNC(=O)C[C@H]1C2=NN=C(N2C3=C(C=C(C=C3)OC)C(=N1)C4=CC=C(C=C4)Cl)C","Synonyms":"['1260907-17-2', 'molibresib', 'I-BET-762', 'GSK 525762A', 'GSK525762A', 'I-BET762', 'GSK525762', 'GSK-525762', 'UNII-5QIO6SRZ2R', '5QIO6SRZ2R', '2-[(4s)-6-(4-Chlorophenyl)-8-Methoxy-1-Methyl-4h-[1,2,4]triazolo[4,3-A][1,4]benzodiazepin-4-Yl]-N-Ethylacetamide', 'Molibresib (USAN)', '4H-[1,2,4]Triazolo[4,3-a][1,4]benzodiazepine-4-acetamide, 6-(4-chlorophenyl)-N-ethyl-8-methoxy-1-methyl-, (4S)-', 'MOLIBRESIB [INN]', 'MOLIBRESIB [USAN]', 'CS-0717', 'MOLIBRESIB [WHO-DD]', 'DTXSID60677590', 'IBET compound', 'I-BET compound', '(4S)-6-(4-CHLOROPHENYL)-N-ETHYL-8-METHOXY-1-METHYL-4H-(1,2,4)TRIAZOLO(4,3-A)(1,4)BENZODIAZEPINE-4-ACETAMIDE', '(4S)-6-(4-Chlorophenyl)-N-ethyl-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine-4-acetamide', '2-((4S)-6-(4-CHLOROPHENYL)-8-METHOXY-1-METHYL-4HBENZO(F)(1,2,4)TRIAZOLO(4,3-A)(1,4)DIAZEPIN-4-YL)-N-ETHYLACETAMIDE', '4H-(1,2,4)TRIAZOLO(4,3-A)(1,4)BENZODIAZEPINE-4-ACETAMIDE, 6-(4-CHLOROPHENYL)-N-ETHYL-8-METHOXY-1-METHYL-, (4S)-', 'molibresibum', '2-((4S)-6-(4-Chlorophenyl)-8-methoxy-1-methyl-4H-(1,2,4)triazolo(4,3-a)(1,4)benzodiazepin-4-yl)-N-ethylacetamide', 'DTXCID50628339', 'I-BET 762', 'Bet inhibitor GSK525762', 'GSK-525762A', '(S)-2-(6-(4-Chlorophenyl)-8-methoxy-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)-N-ethylacetamide', 'CHEMBL1232461', 'GSK-525762A (I-BET 762)', '(S)-2-(6-(4-Chlorophenyl)-8-methoxy-1-methyl-4H-benzo-[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)-N-ethylacetamide', '2-((4S)-6-(4-Chlorophenyl)-8-methoxy-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)-N-ethylacetamide', 'EAM', 'GSK 525762A; I-BET 762', '2yek', 'GSK525762A(Molibresib I-BET762)', 'MFCD22417091', '3p5o', 'GSK 525762A;Molibresib', 'Molibresib (I-BET-762)', 'GTPL7033', 'SCHEMBL1872390', 'CHEBI:95082', 'EX-A462', 'AAAQFGUYHFJNHI-SFHVURJKSA-N', 'GLXC-04299', 'BCP07337', 'BDBM50365463', 'NSC774829', 's7189', 'AKOS025404837', 'CCG-208698', 'NSC-774829', 'NCGC00263621-02', 'NCGC00263621-04', 'NCGC00263621-06', 'NCGC00263621-09', 'NCGC00263621-16', 'AC-32712', 'AS-16364', 'BP-23442', 'FG137683', 'HY-13032', 'GSK-525762A(I-BET-762)', 'I-BET762, >=98% (HPLC)', 'SW220225-1', 'D11326', 'EN300-20050078', 'BRD-K08109215-001-06-4', 'Q27078016', '2-[(4S)-6-(4-Chlorophenyl)-1-methyl-8-(methyloxy)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide', '2-[(7S)-9-(4-chlorophenyl)-12-methoxy-3-methyl-2,4,5,8-tetraazatricyclo[8.4.0.0(2),?]tetradeca-1(10),3,5,8,11,13-hexaen-7-yl]-N-ethylacetamide', '2-[(7S)-9-(4-CHLOROPHENYL)-12-METHOXY-3-METHYL-2,4,5,8-TETRAAZATRICYCLO[8.4.0.0(2),?]TETRADECA-1(14),3,5,8,10,12-HEXAEN-7-YL]-N-ETHYLACETAMIDE', '2-[(7S)-9-(4-chlorophenyl)-12-methoxy-3-methyl-2,4,5,8-tetraazatricyclo[8.4.0.0,2,6]tetradeca-1(10),3,5,8,11,13-hexaen-7-yl]-N-ethylacetamide']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Mi","PubChemCID":"892","SMILES":"C1(C(C(C(C(C1O)O)O)O)O)O","Synonyms":"['inositol', 'myo-inositol', '6917-35-7', 'Myoinositol', 'mesoinositol', 'Inosite', 'Insitolum', 'Isoinositol', 'Inositol, i-', 'Inositol (VAN)', '1D-myo-Inositol', '1L-myo-Inositol', 'CCRIS 6745', '1,2,3,5-trans-4,6-Cyclohexanehexol, cis-', 'Inositol, myo', 'AI3-16111', 'NSC8101', 'NSC-8101', '1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE', 'NSC-25142', 'NSC-55551', 'NSC-404118', 'DTXSID7023146', 'NSC55552', '(1r,2R,3S,4s,5R,6S)-cyclohexane-1,2,3,4,5,6-hexol', '4L6452S749', 'DTXCID2065254', '(1R,2S,3r,4R,5S,6s)-cyclohexane-1,2,3,4,5,6-hexol', 'Chiro Inositol', 'EINECS 201-781-2', 'inositols', 'inositolum', 'iInositol', 'Inositol [Nonspecific isomer]', 'Muscle sugar', 'Inositol, i', 'Inositol (NF)', 'EINECS 230-024-9', 'NSC 25142', 'Inositol [USAN:NF]', 'INOSITOL, MESO', 'INOSITOL [INCI]', 'INOSITOL [USAN]', 'INOSITOL [FCC]', 'INOSITOL [INN]', 'orthorhombic myo-inositol', 'INOSITOL [MI]', 'INOSITOL [VANDF]', 'INOSITOL [MART.]', 'INOSITOL [USP-RS]', 'INOSITOL [WHO-DD]', 'DTXCID7065257', 'CHEBI:24848', 'DTXSID30110000', 'MYO-INOSITOL [EP MONOGRAPH]', 'cis1,2,3,5trans4,6Cyclohexanehexol', '1,2,3,5trans4,6Cyclohexanehexol, cis', 'cyclohexane-1R,2R,3S,4S,5R,6S-hexol', '230-024-9', 'cdaismweouebre-uhfffaoysa-n', 'Scyllo-inositol', 'epi-Inositol', 'Muco-Inositol', 'Allo-inositol', 'i-Inositol', '87-89-8', 'meso-Inositol', 'Neo-inositol', 'D-chiro-Inositol', '488-59-5', '643-12-9', '1L-Chiro-inositol', 'cis-Inositol', 'D-(+)-chiro-Inositol', '1D-Chiro-inositol', '488-58-4', 'cyclohexane-1,2,3,4,5,6-hexol', 'Cyclohexane-1,2,3,4,5,6-hexaol', 'Scyllitol', '551-72-4', 'Quercinitol', '41546-34-3', 'Cocositol', '643-10-7', 'Meat sugar', 'Myoinosite', 'Dambose', 'chiro-inositol', 'Inositene', 'Inositina', 'Phaseomannite', 'Inosital', 'Inositol, myo-', 'Iso-inositol', '488-55-1', 'L-chiro-Inositol', 'Cyclohexitol', 'Phaseomannitol', 'Mesoinosit', 'Mesoinosite', 'Scyllite', 'Mesovit', 'Nucite', 'Mesol', 'D-chiro Inositol', 'Cyclohexanehexol', 'Inositol, meso-', '488-54-0', 'cis-1,2,3,5-trans-4,6-Cyclohexanehexol', 'L-(-)-chiro-Inositol', 'D-myo-Inositol', '576-63-6', 'Bios I', 'Levoinositol', '(-)-Inositol', 'd-Inositol', 'L-Inositol', 'L-myo-Inositol', 'Inositol, allo-', 'Inositol, muco-', 'Inositol, scyllo-', 'alloinositol', 'neoinositol', 'Hexahydroxycyclohexane', 'scyllo-Cyclohexanehexol', '(1R,2R,3S,4S,5S,6S)-Cyclohexane-1,2,3,4,5,6-hexaol', 'Inositol, cis-', 'Inositol, epi-', 'Inositol, neo-', 'epi-Cyclohexanehexol', '(+)-Inositol', '38876-99-2', '(-)-chiro-Inositol', 'ELND005', 'Rat antispectacled eye factor', '(+)-Chiro-Inositol', '(1R,2R,3S,4R,5r,6S)-cyclohexane-1,2,3,4,5,6-hexaol', 'MFCD00077932', 'Matezodambose', 'AZD 103', 'Chiro-inositol, (-)-', '(1r,2R,3S,4r,5R,6S)-cyclohexane-1,2,3,4,5,6-hexol', '1,2,3,4,5,6-Cyclohexanehexol', 'MFCD00065455', '(1r,2r,3r,4r,5r,6r)-cyclohexane-1,2,3,4,5,6-hexol', '(1R,2R,3R,4R,5S,6S)-cyclohexane-1,2,3,4,5,6-hexol', '1-L-chiro-Inositol', 'Inositol, D-chiro-', 'CHEBI:17268', '1,3,5/2,4,6-cyclohexanehexol', '1,2,3,5/4,6-Cyclohexanehexol', 'NSC 8101', 'Chiro-inositol, (+)-', '(1R,2R,3R,4R,5S,6S)-Cyclohexane-1,2,3,4,5,6-hexaol', '(1R,2R,3R,4S,5S,6s)-cyclohexane-1,2,3,4,5,6-hexaol', '(1R,2R,3S,4S,5S,6S)-cyclohexane-1,2,3,4,5,6-hexol', 'NSC404118', 'myo-Inositol;meso-Inositol', '1,2,3,4,5,6-Hexahydroxycyclohexane', 'NSC 404118', 'J101.890F', 'J101.891D', '(1s,2s,3s,4s,5s,6s)-cyclohexane-1,2,3,4,5,6-hexol', '63GQX5QW03', '8LQ63P85IC', '9O6Y5O4P9W', 'ELND-005', 'R1Y9F3N15A', '(1r,2R,3R,4s,5S,6S)-cyclohexane-1,2,3,4,5,6-hexol', '(1s,2R,3R,4s,5S,6S)-cyclohexane-1,2,3,4,5,6-hexol', 'MI', 'CHEBI:10642', 'CHEBI:23927', 'CHEBI:27372', 'CHEBI:27987', 'AZD-103', '4661D3JP8D', '6R79WV4R10', 'M94176HJ2F', 'Inositol (VAN8C', 'NSC45517', 'NSC55551', 'NSC-55552', 'NSC-55558', '1VS4X81277', 'NSC-103959', 'NSC-127230', 'INS', 'NCGC00159409-02', '(1R,2R,3S,4R,5S,6S)-cyclohexane-1,2,3,4,5,6-hexol', 'rel-(1r,2r,3r,4r,5r,6r)-Cyclohexane-1,2,3,4,5,6-hexaol', 'rel-(1R,2r,3S,4R,5s,6S)-Cyclohexane-1,2,3,4,5,6-hexaol', '587A93P465', 'Inositol, myo- (8CI)', '1,3,4,5,6-Cyclohexanehexol', '1,3,5/4,6-Cyclohexanehexol', '(1R,2R,3S,4R,5S,6S)-cyclohexane-1,2,3,4,5,6-hexaol', '1,2,4/3,5,6-cyclohexanehexol', '(1R,2R,3S,4S,5S,6R)-CYCLOHEXANE-1,2,3,4,5,6-HEXOL', 'Mouse antialopecia factor', '1,2,3,4,5,6-Cyclohexanehexol #', 'cis-1,2,3,4,5,6-cyclohexanehexol', 'D-muco-Inositol', 'CAS-87-89-8', 'cis-1,3,5-trans-4,6-Cyclohexanehexol', 'SMR000857145', 'SMR000857319', 'SMR000857320', 'ELND 005', 'SR-05000001655', '1,3,5/2,4,6-Hexahydroxycyclohexane', 'UNII-63GQX5QW03', 'UNII-8LQ63P85IC', 'UNII-9O6Y5O4P9W', 'UNII-R1Y9F3N15A', 'an inositol', 'UNII-4661D3JP8D', 'UNII-6R79WV4R10', 'UNII-M94176HJ2F', 'inositol myo-', 'UNII-1VS4X81277', '4irx', 'Inositol, chiro-', 'rac-chiro-inositol', 'UNII-4L6452S749', 'UNII-587A93P465', 'Inosital (TN)', 'CBU', 'EINECS 207-681-5', 'EINECS 207-682-0', 'EINECS 209-000-7', 'EINECS 211-393-5', 'EINECS 211-394-0', 'MFCD00003863', 'MFCD00272608', 'EPIINOSITOL', '(+)-Epi-Inositol', 'CHIRO-INOSITOLS', 'allo-Inositol, 97%', 'i-Inositol (Standard)', 'Spectrum_001595', '2os9', 'D-(+)-Chiro Inositol', 'DL-CHIRO-INOSITOL', 'INOSITOL (D)', 'INOSITOL (L)', 'Spectrum3_001053', 'Spectrum4_001193', 'Spectrum5_000961', 'myo-Inositol, >=99%', 'meso-Inositol; i-Inositol', 'bmse000102', 'bmse000103', 'bmse000113', 'bmse000901', 'bmse000922', 'Epitope ID:144993', 'scyllo-Inositol, >=98%', 'SCHEMBL5831', 'SCHEMBL5832', 'SCHEMBL5969', 'NCIOpen2_008191', 'BSPBio_002606', 'KBioGR_001885', 'KBioSS_002075', 'MLS001332377', 'MLS001332378', 'MLS001335965', 'MLS001335966', 'MLS001335967', 'MLS001335968', 'SCHEMBL187278', 'SCHEMBL187397', 'SCHEMBL187796', 'SCHEMBL188106', 'SCHEMBL188237', 'SCHEMBL491333', 'SCHEMBL959404', 'SCHEMBL959405', 'CHEMBL278373', 'CHEMBL468154', 'GTPL4495', 'GTPL4645', 'GTPL4648', 'GTPL4649', 'MEGxp0_001817', 'SCHEMBL1055883', 'SCHEMBL4748543', 'SCHEMBL6378921', 'SCHEMBL6468882', 'CHEMBL1222251', 'CHEMBL1231671', 'CHEMBL1950780', 'CHEMBL3976780', 'SCHEMBL12371461', 'SCHEMBL12377889', 'SCHEMBL12411898', 'SCHEMBL12711208', 'SCHEMBL12735687', 'SCHEMBL13058696', 'SCHEMBL13207905', 'SCHEMBL14542470', 'SCHEMBL21388397', 'ACon1_002457', 'CHEBI:22357', 'CHEBI:23311', 'CHEBI:25492', 'CHEBI:27374', 'D-(+)-chiro-Inositol, 95%', 'HY-B1411R', 'KBio2_002075', 'KBio2_004643', 'KBio2_007211', 'KBio3_001826', 'L-(-)-chiro-Inositol, 95%', 'DTXSID50905091', 'myo-Inositol, p.a., 98.0%', 'CDAISMWEOUEBRE-GNIYUCBRSA-N', 'CDAISMWEOUEBRE-GPIVLXJGSA-N', 'CDAISMWEOUEBRE-LOLGQZEGSA-N', 'CDAISMWEOUEBRE-NIPYSYMMSA-N', 'CDAISMWEOUEBRE-OQYPVSDDSA-N', '1,2,3,4,5/6-cyclohexanehexol', '1,2,3,4/5,6-cyclohexanehexol', '1,2,3/4,5,6-cyclohexanehexol', '1,2,4,5/3,6-cyclohexanehexol', 'DTXSID101028818', 'DTXSID101028820', 'DTXSID201028823', 'DTXSID301028826', 'DTXSID601028825', 'DTXSID901028824', 'HMS2091N13', 'HMS2230N03', 'HMS2235H05', 'HMS2235M23', 'HMS3369B06', 'HMS3369F20', 'HMS3373E05', 'Pharmakon1600-01500352', 'D-CHIRO-INOSITOL [USP-RS]', 'D-CHIRO-INOSITOL [WHO-DD]', 'BCP25172', 'HY-B1411', 'HY-N3021', 'NSC25142', 'NSC55558', 'TCA92244', 'Tox21_111642', 'Tox21_302035', 'CCG-36096', 'cis-Inositol, >=98.0% (TLC)', 'MFCD00799555', 'MFCD01321249', 'NSC 55552', 'NSC 55558', 'NSC-45517', 'NSC103959', 'NSC127230', 'NSC757076', 's4530', 'STL453612', 'epi-Inositol, >=98.0% (HPLC)', '1,2,3,4,5,6/0-cyclohexanetetrol', 'AKOS006240678', 'AKOS006332036', 'AKOS015895894', 'AKOS015912905', 'AKOS015912934', 'AKOS015960429', 'AKOS015960633', 'AKOS015994742', 'AKOS024318869', 'AKOS027320475', 'AKOS027327401', 'Tox21_111642_1', 'CS-4782', 'CS-W010757', 'CS-W017225', 'DB03106', 'DB13178', 'DB15350', 'HY-W010041', 'HY-W016509', 'HY-W021265', 'HY-W127726', 'J9.771C', 'KS-1284', 'KS-1420', 'MI07483', 'MI07484', 'MI07497', 'MI07514', 'MI08354', 'MI10118', 'MM16809', 'NSC 103959', 'NSC 127230', 'NSC-757076', 'SB44732', 'SB45039', 'SB46764', 'SB46855', 'D-chiro-Inositol, >=98.0% (HPLC)', 'NCGC00159409-03', 'NCGC00159409-04', 'NCGC00159409-07', 'NCGC00159409-08', 'NCGC00169828-01', 'NCGC00178580-01', 'NCGC00178580-03', 'NCGC00255362-01', 'AC-11070', 'AS-10616', 'AS-68396', 'AS-68424', 'LS-13189', 'MI170214', 'MI176689', 'NCI60_041778', 'SY060836', 'rac-chiro-1,2,3,4,5,6-cyclohexanehexol', 'SBI-0051369.P003', 'cis-1,2,4-trans-3,5,6-Cyclohexanehexol', 'DB-051583', 'DB-051584', 'DB-054642', 'HY-121962', 'J101.888D', 'J101.889B', 'J101.892B', 'myo-Inositol, for microbiology, >=99.0%', 'CS-0023004', 'CS-0039882', 'CS-0083766', 'CS-0185922', 'CS-0369552', 'I0040', 'I0628', 'I0629', 'I0630', 'I0631', 'I0632', 'I0633', 'NS00007581', 'NS00074234', 'NS00079417', 'NS00079658', 'NS00080052', 'NS00080101', 'NS00080335', 'S6176', 'EN300-82941', 'myo-Inositol, BioUltra, >=99.5% (HPLC)', 'myo-Inositol, SAJ special grade, >=99.0%', 'myo-Inositol, Vetec(TM) reagent grade, 99%', 'C00137', 'C06151', 'C06152', 'C06153', 'C19891', 'D08079', 'D78450', 'D91187', 'D91188', 'D91189', 'E78671', 'EN300-658805', 'F19572', 'I-6500', 'M01914', 'T72516', 'AB00051982_13', 'EN300-7361851', 'EN300-7411506', 'A836375', 'EN300-19631206', 'EN300-19632288', 'EN300-25914216', 'Q407997', 'Q743661', 'Q2838375', 'Q2974313', 'Q3011024', 'Q3023527', 'Q3205874', 'Q3331426', 'Q3347078', 'Q3589114', 'SR-05000001655-1', 'SR-05000001655-5', '1,2,4/3,5,6-Cyclohexane-1,2,3,4,5,6-hexol', '7B0CEF84-D9CE-4A88-AA7D-EC50C89387A5', 'BRD-K52618540-001-09-9', '1D7A27BF-6060-4FA9-AC46-3BD18DBA406E', '220128F1-89BF-442D-AD6D-E6D1EA7BA625', 'Z1486007281', '(1R,2S,3r,4R,5S,6r)-cyclohexane-1,2,3,4,5,6-hexol', '(1R,2S,3s,4R,5S,6s)-cyclohexane-1,2,3,4,5,6-hexol', 'Inositol, United States Pharmacopeia (USP) Reference Standard', 'myo-Inositol, European Pharmacopoeia (EP) Reference Standard', 'rel-(1S,2s,3s,4s,5s,6s)-cyclohexane-1,2,3,4,5,6-hexaol', '1,2,3,4,5,6-Cyclohexanehexol, (cis,cis,cis,trans,cis,trans)- #', '1,2,3,4,5,6-cyclohexanehexol, (1alpha,2alpha,3alpha,4beta,5alpha,6beta)', 'Inositol, Pharmaceutical Secondary Standard; Certified Reference Material', '1.ALPHA.,2.ALPHA.,3.BETA.,4.ALPHA.,5.BETA.,6.BETA.-CYCLOHEXANEHEXOL', '2H3', 'myo-Inositol, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Regorafenib","PubChemCID":"11167602","SMILES":"CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F","Synonyms":"['Regorafenib', '755037-03-7', 'BAY 73-4506', 'Regorafenibum', 'BAY73-4506', 'BAY-73-4506', '4-[4-({[4-Chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide', 'UNII-24T2A1DOYB', 'REGORAFENIB ANHYDROUS', '24T2A1DOYB', 'CHEBI:68647', 'Bay-734506', 'DTXSID60226441', '4-(4-(((4-chloro-3-(trifluoromethyl)phenyl)carbamoyl)amino)-3-fluorophenoxy)-n-methylpyridine-2-carboxamide', 'UNII-MGN125FS9D', 'REGORAFENIB (USP-RS)', 'CHEBI:68646', 'DTXSID70144349', 'REGORAFENIB (USP MONOGRAPH)', '4-(4-(((4-chloro-3-(trifluoromethyl)phenyl)carbamoyl}amino)-3-fluorophenoxy)-N-methylpyridine-2-carboxamide', 'DTXCID8066840', 'DTXCID60148932', 'L01XE21', '755037-03-7 (anhydrous); 1019206-88-2 (hydrate)', '4-(4-(((4-chloro-3-(trifluoromethyl)phenyl)carbamoyl)amino)-3-fluorophenoxy)-n-methylpyridine-2-carboxamide--water (1/1)', '755037-03-7, regorafenib', 'Stivarga', '4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide', 'Regorafenib (BAY 73-4506)', '4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide', '2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-', 'CHEMBL1946170', 'Stivarga (TN)', 'Regorafenib [INN]', 'Regorafenib [USAN:INN]', 'C21H15ClF4N4O3', 'MFCD16038047', 'Regorafenib (Standard)', 'REGORAFENIB [MI]', 'Regorafenib (USAN/INN)', 'REGORAFENIB [VANDF]', 'BAY73-4506 hydrochloride', 'REGORAFENIB [WHO-DD]', '835621-08-4', 'MLS006010303', 'Regorafenib crystalline form I', 'SCHEMBL432230', 'Regorafenib,BAY 73-4506', 'GTPL5891', 'EX-A058', 'BCPP000352', 'HMS3654K16', 'HMS3672E15', '755037-03-7 , Regorafenib', 'BCP02105', 'BDBM50363397', 'HY-10331R', 'NSC763932', 'NSC800865', 's1178', 'AKOS015951107', 'BCP9000384', 'CCG-269571', 'CS-0170', 'DB08896', 'FR16116', 'NSC-763932', 'NSC-800865', 'SB16819', 'SDCCGSBI-0654355.P001', 'NCGC00263138-01', 'NCGC00263138-13', 'NCGC00263138-19', '4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluoro-phenoxy]-N-methyl-pyridine-2-carboxamide', 'AC-25075', 'AC-31116', 'AS-16304', 'HY-10331', 'SMR004701370', 'NS00040710', 'R0142', 'SW218097-2', 'cas:835621-07-3;Regorafenib hydrochloride', 'Regorafenib (BAY73-4506,Fluoro-Sorafenib)', 'D10138', 'Regorafenib (BAY73-4506,Fluoro-Sorafenib)?', 'AB01565826_02', 'SR-01000941571', 'Q3891664', 'SR-01000941571-1', 'BRD-K16730910-001-02-4', 'BRD-K16730910-001-07-3', 'Z2235801830', '4-[4-({[4-Chloro-3-(trifluoromethy)phenyl]carbamoyl}amino)-3-fluorophenoxy]-1-methylpyridine-2-carboxamide', '4{4-[3-(4-chloro-3-trifluoromethylphenyl)-ureido]-3-fluorophenoxy}-pyridine-2-carboxylic acid methylamide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Nilotinib","PubChemCID":"644241","SMILES":"CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5","Synonyms":"['Nilotinib', '641571-10-0', 'nilotinibum', '4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide', 'NSC-747599', 'CHEBI:52172', 'HSDB 7842', 'UNII-F41401512X', '4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide', '4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide', 'DTXSID5042663', 'F41401512X', 'EC 700-544-5', 'NSC 747599', '4-Methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide', 'NILOTINIB (MART.)', 'NILOTINIB [MART.]', 'NILOTINIB (USP-RS)', 'NILOTINIB [USP-RS]', 'benzamide, 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-', 'N-(3-(3-(1H-Imidazolyl)propoxy)phenyl)-4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)benzamide', '4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl]benzamide', 'Benzamide, 4-methyl-N-((3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(4-(3-pyridinyl)-2-pyrimidinyl)amino)-', '4-METHYL-N-(3-(4-METHYL-1H-IMIDAZOL-1-YL)-5-(TRIFLUOROMETHYL)PHENYL)-3-((4-PYRIDIN-3-YLPYRIMIDIN-2-YL)AMINO)BENZAMIDE', 'BENZAMIDE, 4-METHYL-N-(3-(4-METHYL-1H-IMIDAZOL-1-YL)-5-(TRIFLUOROMETHYL)PHENYL)-3-((4-(3-PYRIDINYL)-2-PYRIMIDINYL)AMINO)-', 'AMN 107 Base Form', 'DTXCID3022663', 'L01XE08', 'Tasigna', 'AMN107', 'AMN 107', 'AMN-107', 'Nilotinib (AMN-107)', 'Nilotinib free base', 'MFCD09833716', '4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide', '4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide', 'CHEMBL255863', 'Danziten', '641571-10-0 (free base)', 'NSC747599', '4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzamide', '4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-{(4-(pyridin-3-yl)pyrimidin-2-yl)amino}benzamide', '4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide', 'Nilotinib,AMN107,Tasigna;4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide', 'SMR002544680', 'Nilotinib [USAN]', 'C28H22F3N7O', 'Nilotinib [USAN:INN:BAN]', 'Nilotinib?', 'Nilotinib (Standard)', '3gp0', 'NILOTINIB [INN]', 'NILOTINIB [MI]', 'Nilotinib (USAN/INN)', 'NILOTINIB [HSDB]', '1353151-22-0', 'NILOTINIB [VANDF]', 'NILOTINIB [WHO-DD]', 'SCHEMBL7901', 'NILOTINIB [EMA EPAR]', 'MLS003915611', 'MLS006010160', 'Nilotinib - Bio-X trade mark', 'GTPL5697', 'BCPP000149', 'HMS3244A13', 'HMS3244A14', 'HMS3244B13', 'HMS3295A23', 'HMS3654M07', 'HMS3748E11', 'BCP01367', 'EX-A8380', 'TAC35617', 'AC-647', 'BDBM50237710', 'HY-10159R', 'NSC800804', 's1033', 'AKOS005063561', 'BCP9000989', 'CCG-264784', 'CS-0102', 'DB04868', 'FM10831', 'NSC-800804', 'SB17315', 'SDCCGSBI-0634418.P004', 'NCGC00183285-01', 'NCGC00183285-03', 'NCGC00183285-04', 'NCGC00183285-09', 'NCGC00183285-15', '4-Methyl-3-(4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl]benzamide', '4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)-phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide', 'AS-16214', 'BN164654', 'HY-10159', 'SY024415', 'NS00000665', 'SW218083-2', 'D08953', 'N-8207', 'AB01273978-01', 'AB01273978-02', 'AB01273978_03', 'EN300-7381984', 'Q412327', 'SR-01000931150', 'SR-01000931150-2', 'BRD-K81528515-001-04-7', 'BRD-K81528515-001-13-8', 'Z1741976994', '4-Methyl-N-[3-(4-methyl-1-imidazolyl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridyl)-2-pyrimidyl]amino]benzamide', '4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide', '4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4 -pyridin-3-ylpyrimidin-2-yl)amino]benzamide', '4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino] benzamide', 'Benzamide, 4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(4-(3-pyridinyl)-2-pyrimidinyl)amino)-', 'Benzamide, 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]- (9CI)']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Amiodarone","PubChemCID":"2157","SMILES":"CCCCC1=C(C2=CC=CC=C2O1)C(=O)C3=CC(=C(C(=C3)I)OCCN(CC)CC)I","Synonyms":"['amiodarone', '1951-25-3', 'Amiodaronum', 'Amjodaronum', 'Amiodaronum [INN-Latin]', 'Amiodarona [INN-Spanish]', '2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran', \"2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran\", 'UNII-N3RQ532IUT', 'EINECS 217-772-1', 'N3RQ532IUT', '2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone', 'BRN 1271711', 'CCRIS 9360', 'CHEBI:2663', 'DTXSID7022592', '2-Butyl-3-benzofuranyl p-((2-diethylamino)ethoxy)-m,m-diiodophenyl ketone', '(2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone', '2-Butyl-3-(3,5-diiodo-4-(beta-diethylaminoethoxy)benzoyl)benzofuran', \"2-Butyl-3-(4'-beta-N-diethylaminoethoxy-3',5'-diiodobenzoyl)benzofuran\", 'Ketone, 2-butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl', '(2-Butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diidophenyl)methanone', 'Methanone, (2-butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)-', 'DTXCID702592', '5-18-02-00353 (Beilstein Handbook Reference)', 'Methanone, (2-butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]-', 'Amiodaronum (INN-Latin)', 'Amiodarona (INN-Spanish)', 'AMIODARONE (MART.)', 'AMIODARONE [MART.]', '2-Butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone', '(2-butyl-1-benzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)methanone', 'C01BD01', '217-772-1', 'Cordarone', 'Amiodarona', 'L 3428', 'L-3428', 'CHEMBL633', '(2-Butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl)methanone', 'Amidorone', '(2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}ethyl)diethylamine', '(2-butyl-1-benzofuran-3-yl)-[4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone', 'NCGC00015096-07', 'Amiodarone Base', '(2-butyl-1-benzofuran-3-yl)(4-{[2-(diethylamino)ethyl]oxy}-3,5-diiodophenyl)methanone', 'CAS-1951-25-3', 'NCGC00015096-12', 'Amiodarone (USAN/INN)', 'CAS-19774-82-4', 'AmiodaroneHCl', 'Amiodarone [USAN:INN:BAN]', 'BBI', 'Labaz (Salt/Mix)', 'Cyto8E2', 'Cordarone (Salt/Mix)', 'Spectrum_000261', 'Amiodarone N-oxide HCl', 'CRD - Cardiac mixture', 'AMIODARONE [MI]', 'AMIODARONE [INN]', 'Prestwick0_000409', 'Prestwick1_000409', 'Prestwick2_000409', 'Prestwick3_000409', 'Spectrum2_001813', 'Spectrum3_001050', 'Spectrum4_001190', 'Spectrum5_001533', 'AMIODARONE [USAN]', 'Lopac-A-8423', 'AMIODARONE [VANDF]', 'AMIODARONE [WHO-DD]', 'BIDD:PXR0146', 'CBiol_001740', 'Lopac0_000122', 'SCHEMBL16284', 'BSPBio_000338', 'BSPBio_001574', 'BSPBio_002580', 'KBioGR_000294', 'KBioGR_001859', 'KBioSS_000294', 'KBioSS_000741', 'BIDD:GT0425', 'DivK1c_000079', 'SPBio_001825', 'SPBio_002277', 'BPBio1_000372', 'cid_441325', 'GTPL2566', 'BDBM18957', 'KBio1_000079', 'KBio2_000294', 'KBio2_000741', 'KBio2_002862', 'KBio2_003309', 'KBio2_005430', 'KBio2_005877', 'KBio3_000587', 'KBio3_000588', 'KBio3_001800', 'NINDS_000079', 'Bio1_000026', 'Bio1_000515', 'Bio1_001004', 'Bio2_000294', 'Bio2_000774', 'GLXC-10157', 'HMS1791O16', 'HMS1989O16', 'HMS2089C07', 'SKF-33134-A (Salt/Mix)', 'BAA95125', 'Tox21_110083', 'MFCD00242801', 'STK529812', '{2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl}diethylamine', 'AKOS005462717', 'Tox21_110083_1', 'CCG-204217', 'DB01118', 'SDCCGSBI-0050110.P004', '(2-Butylbenzofuran-3-yl)(4-(2-(diethylamino)-ethoxy)-3,5-diiodophenyl)methanone', '(2-butylbenzofuran-3-yl)-[4-(2-diethylaminoethoxy)-3,5-diiodo-phenyl]-methanone', 'IDI1_000079', 'IDI1_034044', 'QTL1_000008', 'NCGC00015096-01', 'NCGC00015096-02', 'NCGC00015096-03', 'NCGC00015096-04', 'NCGC00015096-05', 'NCGC00015096-06', 'NCGC00015096-08', 'NCGC00015096-09', 'NCGC00015096-10', 'NCGC00015096-11', 'NCGC00015096-13', 'NCGC00015096-14', 'NCGC00015096-17', 'NCGC00015096-29', 'NCGC00024242-03', 'NCGC00024242-04', 'NCGC00024242-05', 'NCGC00024242-06', 'HY-14187', 'IA156918', 'NCI60_041885', 'SBI-0050110.P003', 'AB00053422', 'NS00010453', 'UNM000001215003', 'C06823', 'D02910', 'EN300-708787', 'G78136', 'AB00053422-17', 'AB00053422_18', 'AB00053422_19', 'L001174', 'Q410061', 'BRD-K17561142-003-16-8', 'BRD-K17561142-003-32-5', 'BRD-K17561142-003-33-3', 'BRD-K17561142-003-35-8', 'F2173-1018', '2-Butyl-3-(3,5-diiodo-4-(.beta.-diethylaminoethoxy)benzoyl)benzofuran', \"2-Butyl-3-(4'-.beta.-N-diethylaminoethoxy-3',5'-diiodobenzoyl)benzofuran\", '(2-butyl-1-benzofuran-3-yl)-[4-(2-diethylaminoethoxy)-3,5-diiodophenyl]methanone', '(2-Butyl-benzofuran-3-yl)(4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl)methanone #', '(2-butylbenzofuran-3-yl)-[4-(2-diethylaminoethyloxy)-3,5-diiodo-phenyl]methanone', '(2-n-butyl-3-benzofuranyl) [4-[2-(diethylamino)ethoxyl]-3,5-diiodophenyl] methanone', '(2-n-butyl-3-benzofuranyl)[4-[2-(diethylamino)ethoxyl]-3,5-diiodophenyl]methanone']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Ar a014418","PubChemCID":"448014","SMILES":"COC1=CC=C(C=C1)CNC(=O)NC2=NC=C(S2)[N+](=O)[O-]","Synonyms":"['AR-A014418', '487021-52-3', \"N-(4-METHOXYBENZYL)-N'-(5-NITRO-1,3-THIAZOL-2-YL)UREA\", 'AR-AO-14418', 'GSK 3beta inhibitor VIII', 'SN 4521', 'SN-4521', '87KSH90Q6D', 'AR-014418', 'AR-0133418', 'GSK-3beta inhibitor VIII AR-A014418', \"Urea, N-((4-methoxyphenyl)methyl)-N'-(5-nitro-2-thiazolyl)-\", 'DTXSID80332270', 'GSK 3.BETA. INHIBITOR VIII', 'AR A014418', 'DTXCID30283364', '637-170-6', '1-(4-methoxybenzyl)-3-(5-nitrothiazol-2-yl)urea', 'GSK-3beta Inhibitor VIII', '1-[(4-methoxyphenyl)methyl]-3-(5-nitro-1,3-thiazol-2-yl)urea', 'AR-AO 14418', 'AR-A 014418', 'GSK-3b', 'MFCD08277040', '871843-09-3', 'CHEMBL259850', 'AR-AO14418-d3', \"N-[(4-Methoxyphenyl)methyl]-N'-(5-nitro-2-thiazolyl)urea\", 'GSK-3|A Inhibitor VIII', 'UNII-87KSH90Q6D', 'Kinome_1268', '1q5k', 'GSK-3b inhibitor VIII', 'GSK-3 beta Inhibitor VIII', '1276635-87-0', 'SCHEMBL143499', 'GTPL5979', 'SCHEMBL14401217', 'EX-A266', 'CHEBI:232162', 'YAEMHJKFIIIULI-UHFFFAOYSA-N', 'AR-AO14418', 'HMS3229G16', 'HMS3653F03', 'HMS3886J15', 'BCP07893', 'RYB90863', 'WJB84309', 'BDBM50229962', 'HB1258', 'HSCI1_000278', 's7435', 'GSK-3beta Inhibitor XXVI(GSK-3b)', 'AKOS024457901', 'CCG-206843', 'CS-1469', 'DB01950', 'FA17968', 'SB19271', 'SDCCGSBI-0086754.P003', 'NCGC00371125-01', 'NCGC00371125-09', 'NCGC00371125-12', 'AC-32895', 'AS-56197', 'DA-42328', 'HY-10512', 'AR-A014418(GSK3beta Inhibitor VIII)?', 'NS00069314', 'SW219711-1', 'AR-A014418, >=98% (HPLC), solid', 'GSK-3beta Inhibitor VIII - CAS 487021-52-3', 'BRD-K67860401-001-01-5', 'BRD-K67860401-001-03-1', 'BRD-K67860401-001-05-6', 'BRD-K67860401-001-07-2', 'Q27077900', '1-(4-methoxybenzyl)-3-(5-nitro-1,3-thiazol-2-yl)urea', '1-[(4-methoxyphenyl)methyl]-3-(5-nitrothiazol-2-yl)urea', 'AR 0133418; GSK 3B Inhibitor VIII; AR-AO 14418', '1,2-Dihydro-4,5-bis(1-methyl-1H-indol-3-yl)-3H-pyrazol-3-one', \"N-(4-METHOXYBENZYL)-N''-(5-NITRO-1,3-THIAZOL-2-YL)UREA\", \"N-[(4-Methoxyphenyl)methyl]-N'-(5-nitro-2-thiazolyl)urea;AR 0133418;GSK 3B inhibitor VIII\"]","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"FRAX486","PubChemCID":"68060125","SMILES":"CCN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=C(C=C3)Cl)Cl)NC4=CC(=C(C=C4)N5CCNCC5)F","Synonyms":"['FRAX486', '1232030-35-1', 'FRAX-486', 'FRAX 486', '6-(2,4-Dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one', 'Pyrido[2,3-d]pyriMidin-7(8H)-one, 6-(2,4-dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]aMino]-', 'CHEMBL3609326', '6-(2,4-dichlorophenyl)-8-ethyl-2-(3-fluoro-4-piperazin-1-ylanilino)pyrido[2,3-d]pyrimidin-7-one', '6-(2,4-dichlorophenyl)-8-ethyl-2-((3-fluoro-4-(piperazin-1-yl)phenyl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one', '6-(2,4-Dichlorophenyl)-8-Ethyl-2-{[3-Fluoro-4-(Piperazin-1-Yl)phenyl]amino}pyrido[2,3-D]pyrimidin-7(8h)-One', 'GTPL8938', 'SCHEMBL10192789', 'FRAX-486?', 'GLXC-05228', 'BCP13764', 'EX-A2201', 'HZB03035', 'BDBM50112355', 'HY-15542B', 's7807', 'AKOS024458531', 'CCG-269796', 'CS-3548', 'SB17179', 'NCGC00379255-05', 'NCGC00379255-06', 'AC-33021', 'DS-017730', 'C71908', 'BRD-K57243773-001-01-6', 'BRD-K57243773-001-02-4', 'Q27077741', '6-(2,4-dichlorophenyl)-8-ethyl-2-(3-fluoro-4-(piperazin-1-yl)phenylamino)pyrido[2,3-d]pyrimidin-7(8H)-one', 'Pyrido[2,3-d]pyrimidin-7(8h)-one,6-(2,4-dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]-']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Byl719","PubChemCID":"56649450","SMILES":"CC1=C(SC(=N1)NC(=O)N2CCC[C@H]2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F","Synonyms":"['alpelisib', '1217486-61-7', 'Vijoice', 'BYL 719', 'UNII-08W5N2C97Q', '08W5N2C97Q', '1,2-PYRROLIDINEDICARBOXAMIDE, N1-[4-METHYL-5-[2-(2,2,2-TRIFLUORO-1,1-DIMETHYLETHYL)-4-PYRIDINYL]-2-THIAZOLYL]-, (2S)-', '1,2-Pyrrolidinedicarboxamide, N1-(4-methyl-5-(2-(2,2,2-trifluoro-1,1-dimethylethyl)-4-pyridinyl)-2-thiazolyl)-, (2S)-', 'alpelisibum', '(2S)-N1-(4-METHYL-5-(1-(1,1,1-TRIFLUORO-2-METHYLPROPAN-2-YL)PYRIDIN-4-YL)-1,3-THIAZOL-2-YL)PYRROLIDINE-1,2-DICARBOXAMIDE', '(2S)-N1-(4-Methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)-1,3-thiazol-2-yl)pyrrolidine-1,2-dicarboxamide', '(2S)-N1-{4-Methyl-5-[1-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide', '(2S)-N1-{4-METHYL-5-[2-(1,1,1-TRIFLUORO-2-METHYLPROPAN-2-YL)PYRIDIN-4-YL]-1,3-THIAZOL-2-YL}PYRROLIDINE-1,2-DICARBOXAMIDE', 'L01XX65', 'Phosphoinositide 3-kinase Inhibitor BYL719', 'BYL-719', 'BYL719', 'Piqray', 'NVP-BYL719', 'Alpelisib (BYL719)', '(S)-N1-(4-Methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-yl)pyrrolidine-1,2-dicarboxamide', 'Alpelisib [USAN:INN]', '(2S)-1-N-[4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide', 'CHEMBL2396661', '(S)-Pyrrolidine-1,2-dicarboxylic acid 2-amide 1-(4-methyl-5-(2-(2,2,2-trifluoro-1,1-dimethylethyl)-pyridin-4-yl)thiazol-2-yl)amide', 'Alpelisib [INN]', '(2s)-N~1~-{4-Methyl-5-[2-(1,1,1-Trifluoro-2-Methylpropan-2-Yl)pyridin-4-Yl]-1,3-Thiazol-2-Yl}pyrrolidine-1,2-Dicarboxamide', '(S)-N1-(4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-yl)pyrrolidine-1,2-dicarboxamide.', 'C19H22F3N5O2S', '4jps', '(2S)-1-N-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide', '1LT', 'Alpelisib [USAN]', 'Vijoice (TN)', 'MFCD22417085', 'Piqray (TN)', 'ALPELISIB [JAN]', 'ALPELISIB [MI]', 'ALPELISIB [WHO-DD]', 'Alpelisib (JAN/USAN/INN)', 'GTPL7955', 'SCHEMBL1911869', 'ALPELISIB [ORANGE BOOK]', 'CHEBI:93752', 'DTXSID70153355', 'EX-A405', 'STUWGJZDJHPWGZ-LBPRGKRZSA-N', 'BYL 719; BYL719', 'BDBM50436459', 'NSC765974', 'NSC800065', 's2814', 'AKOS022186315', 'CCG-269139', 'CS-0663', 'DB12015', 'FP71607', 'NSC-765974', 'NSC-800065', 'SDCCGSBI-0654479.P001', 'NCGC00346717-03', 'NCGC00346717-06', 'NCGC00346717-12', '(2S)-N1-[4-Methyl-5-[2-(2,2,2-trifluoro-1,1-dimethylethyl)-4-pyridinyl]-2-thiazolyl]-1,2-pyrrolidine', 'AC-37083', 'AS-16349', 'HY-15244', 'NS00072895', 'SW220128-1', 'cas:1217486-61-7;BYL-719', 'D11011', 'EN300-23810842', 'BRD-K54997624-001-06-0', 'Q27074391', '(S)-Pyrrolidine-1,2-dicarboxylic acid 2-amide 1-[4-methyl-5-[2-(2,2,2-trifluoro-1,1-dimethylethyl)-pyridin-4-yl]thiazol-2-yl]amide;A  lpelisib']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Rgfp966","PubChemCID":"56650312","SMILES":"C1=CC=C(C=C1)/C=C/CN2C=C(C=N2)/C=C/C(=O)NC3=C(C=C(C=C3)F)N","Synonyms":"['RGFP966', 'RGFP-966', '(2E)-N-(2-amino-4-fluorophenyl)-3-{1-[(2E)-3-phenylprop-2-en-1-yl]-1H-pyrazol-4-yl}prop-2-enamide', '(2E)-N-(2-amino-4-fluorophenyl)-3-(1-((2E)-3-phenylprop-2-en-1-yl)-1H-pyrazol-4-yl)prop-2-enamide', '1357389-11-7', '1396841-57-8', '(E)-N-(2-amino-4-fluorophenyl)-3-(1-cinnamyl-1H-pyrazol-4-yl)acrylamide', 'RGFP 966', 'RGFP966 Racemate', '(E)-N-(2-amino-4-fluorophenyl)-3-[1-[(E)-3-phenylprop-2-enyl]pyrazol-4-yl]prop-2-enamide', '(E,E)-RGFP966', 'CHEMBL4078477', 'MFCD26960954', 'GTPL7500', 'SCHEMBL12497867', 'SCHEMBL12497871', 'RGFP 966?', 'EX-A229', '(E,E)-N-(2-Amino-4-fluorophenyl)-3-(1-cinnamyl-1H-pyrazol-4-yl)acrylamide', 'CHEBI:131163', 'DTXSID801026037', 'GLXC-05479', 'BCP08102', 'BDBM50254780', 's7229', 'AKOS030526449', 'AKOS037647194', 'CCG-268194', 'HY-W019710', 'NCGC00381560-10', 'RGFP966, >=98% (HPLC)', '(2E)-N-(2-Amino-4-fluorophenyl)-3-[1-(3-phenyl-2-propen-1-yl)-1H-pyrazol-4-yl]-2-propenamide', 'AC-32738', 'AC-35512', 'AS-72773', 'AS-77803', 'FA102555', 'CS-0031332', 'SW219401-1', 'BRD-K61688984-001-02-9', 'Q27088541', '(2E)-N-(2-amino-4-fluorophenyl)-3-[1-(3-phenylprop-2-en-1-yl)-1H-pyrazol-4-yl]prop-2-enamide', '(2E)-N-(2-Amino-4-fluorophenyl)-3-[1-[(2E)-3-phenyl-2-propen-1-yl]-1H-pyrazol-4-yl]-2-propenamide', '(e)-N-(2-amino-4-fluorophenyl)-3-[1-[(e)-3-phenylprop-2-enyl] pyrazol-4-yl]prop-2-enamide', '2-Propenamide, N-(2-amino-4-fluorophenyl)-3-[1-[(2E)-3-phenyl-2-propen-1-yl]-1H-pyrazol-4-yl]-, (2E)-']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"SP600125","PubChemCID":"8515","SMILES":"C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O","Synonyms":"['129-56-6', '1,9-Pyrazoloanthrone', 'SP600125', 'Pyrazolanthrone', 'Dibenzo[cd,g]indazol-6(2H)-one', 'SP 600125', 'Anthra[1,9-cd]pyrazol-6(2H)-one', 'JNK Inhibitor II', 'ANTHRA(1,9-cd)PYRAZOL-6(2H)-ONE', 'NSC 75890', 'NSC75890', 'EINECS 204-955-6', 'BRN 0746890', 'DTXSID2040525', 'UNII-1TW30Y2766', 'CHEBI:90695', '1TW30Y2766', 'CI 70300', 'DTXCID0020525', 'dibenzo(cd,g)indazol-6(2H)-one', '14,15-diazatetracyclo[7.6.1.0^{2,7}.0^{13,16}]hexadeca-1(15),2(7),3,5,9,11,13(16)-heptaen-8-one', '14,15-diazatetracyclo(7.6.1.0^(2,7).0^(13,16))hexadeca-1(15),2(7),3,5,9,11,13(16)-heptaen-8-one', 'acpoujidantyho-uhfffaoysa-n', 'Pyrazoleanthrone', 'SP-600125', 'C.I. 70300', '2H-Dibenzo[cd,g]indazol-6-one', 'NSC-75890', '2h-dibenzo(cd,g)indazol-6-one', 'MFCD00022289', 'CHEMBL7064', 'MLS002693964', 'Anthra-1,9-pyrazol-6-none', '14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1(15),2,4,6,9(16),10,12-heptaen-8-one', 'NCGC00015958-03', 'SMR000015440', 'SR-01000075840', '1pmv', '2zmd', 'Kinome_3844', 'Tocris-1496', 'BiomolKI_000068', 'Lopac-S-5567', 'BiomolKI2_000072', 'cid_8515', 'CBiol_002049', 'Lopac0_000473', 'BMK1-G8', 'BSPBio_001066', 'ChemBiol10705 Compound 4', 'KBioGR_000406', 'KBioSS_000406', 'JMC517015 Compound 2', 'MLS002153267', 'MLS006011577', 'SCHEMBL170980', 'anthra[1,9-cd]pyrazol-6-one', 'GTPL5273', 'Pyrazolanthrone (SP600125)', 'CHEMBL1725279', 'SCHEMBL15583517', 'BCBcMAP01_000053', 'BDBM16018', 'dibenz[cd,g]indazol-6(2h)-one', 'KBio2_000406', 'KBio2_002974', 'KBio2_005542', 'KBio3_000771', 'KBio3_000772', 'Bio1_000335', 'Bio1_000824', 'Bio1_001313', 'Bio2_000373', 'Bio2_000853', 'GLXC-03091', 'HMS1362F07', 'HMS1667K13', 'HMS1792F07', 'HMS1990F07', 'HMS2250C03', 'HMS3229I16', 'HMS3261O08', 'HMS3267P06', 'HMS3295M01', 'HMS3403F07', 'HMS3412F05', 'HMS3654P10', 'HMS3676F05', 'HMS3747M19', 'PS653', 'ALBB-024051', 'Anthra[1,9cd]pyrazol-6(2H)-one', 'BCP05457', 'EX-A1998', 'Tox21_110267', 'Tox21_500473', 'BDBM50024294', 'BDBM50433916', 'CCG-47500', 'Dibenzo[cd,g]indazol-6(2H)-one #', 'HB2234', 'HSCI1_000136', 'NSC755773', 's1460', 'AKOS000115584', 'AKOS040751313', 'Anthrapyrazolone; 1,9-Pyrazoloanthrone', 'CCG-100672', 'CS-0196', 'DB01782', 'FP33726', 'LP00473', 'NSC-755773', 'SDCCGSBI-0050458.P003', 'SDCCGSBI-0050458.P009', 'WLN: T C66651A P IV OMNJ', '1,6-dihydrodibenzo[cd,g]indazol-6-one', '2,6-dihydrodibenzo[cd,g]indazol-6-one', 'IDI1_002128', 'QTL1_000077', 's10332', 'SMP2_000240', 'NCGC00015958-01', 'NCGC00015958-02', 'NCGC00015958-04', 'NCGC00015958-05', 'NCGC00015958-06', 'NCGC00015958-07', 'NCGC00015958-08', 'NCGC00015958-22', 'NCGC00025186-01', 'NCGC00025186-02', 'NCGC00025186-03', 'NCGC00025186-04', 'NCGC00025186-05', 'NCGC00261158-01', 'WLN: T C6665 1A P IV OMNJ', 'AC-32051', 'AS-14374', 'CAS-129-56-6', 'HY-12041', 'JNK Inhibitor II - CAS 129-56-6', 'SMR002530644', 'SY052909', 'DB-041928', 'SP600125?', 'A2548', 'EU-0100473', 'NS00020981', 'SW218106-2', 'EN300-02083', 'Anthra[1,9-cd]pyrazol-6(2H)-one & Z-100', 'K00068', 'S 5567', 'SP600125, >=98% (HPLC)', 'AB00075935-01', 'SP 600125 & Z-100', 'AE-641/00620033', 'Q4545713', 'SR-01000075840-1', 'SR-01000075840-2', 'SR-01000075840-4', 'SR-01000075840-6', 'SR-01000637108-1', 'BRD-K01567962-001-04-0', 'BRD-K01567962-001-06-5', 'BRD-K01567962-001-08-1', 'BRD-K01567962-001-22-2', 'BRD-K01567962-001-23-0', 'BRD-K01567962-001-24-8', 'Z56785477', 'F1414-1245', '14,15-diazatetracyclo[7.6.1.0;{2,7}.0;{13,16}]hexadeca-1(15),2(7),3,5,9(16),10,12-heptaen-8-one', '14,15-diazatetracyclo[7.6.1.0^{2,7}.0^{13,16}]hexadeca-1(15),2,4,6,9(16),10,12-heptaen-8-one']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Ruxolitinib","PubChemCID":"25126798","SMILES":"C1CCC(C1)[C@@H](CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3","Synonyms":"['Ruxolitinib', '941678-49-5', 'R-Ruxolitinib', 'INC424', '(R)-ruxolitinib', 'INCB 018424', 'UNII-82S8X8XX8H', '82S8X8XX8H', 'CHEBI:66919', 'INCB18424', 'INC 424', 'INC-424', '(3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile', 'INCB-18424', 'HSDB 8259', 'DTXSID10240930', '(3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile', '(3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)propanenitrile', '(3R)-3-CYCLOPENTYL-3-(4-(7H-PYRROLO(2,3-D)PYRIMIDIN-4-YL)PYRAZOL-1-YL)PROPANENITRILE', '1H-Pyrazole-1-propanenitrile, beta-cyclopentyl-4-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)-,(betaR)-', 'ruxolitinibum', '(3R)-3-cyclopentyl-3-(4-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile', 'DTXCID40163421', 'L01XE18', 'Oral JAK Inhibitor INCB18424', '3R)-3-cyclopentyl-3-(4-(7H-pyrrolo(2,3-d)pyrimidin-4-yl)pyrazol-1-yl)propanenitrile', '1H-PYRAZOLE-1-PROPANENITRILE, beta-CYCLOPENTYL-4-(7H-PYRROLO(2,3-D)PYRIMIDIN-4-YL)-, (betaR)-', 'INCB018424', 'Ruxolitinib (INCB018424)', '(R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile', 'INCB-018424', '(R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile (Synonyms:Ruxolitinib)', '(R)-Ruxolitinib (>90%)', '(betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile', 'Ruxolitinib [INN]', 'Ruxolitinib [USAN:INN]', 'INCB 18424', '(ssR)-ss-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile; (3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile; (ssR)-ss-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile; INC 424; INCB 018424; Ruxolitinib', 'RXT', 'MFCD12031592', 'Ruxolitinib (Standard)', 'RUXOLITINIB [MI]', 'Ruxolitinib (USAN/INN)', 'INCB18424,Ruxolitinib', 'RUXOLITINIB [USAN]', 'RUXOLITINIB [VANDF]', 'RUXOLITINIB [WHO-DD]', 'SCHEMBL171319', 'GTPL5688', 'CHEMBL1789941', 'SCHEMBL16546708', 'HFNKQEVNSGCOJV-OAHLLOKOSA-N', 'EX-A1670', 'BDBM50355501', 'HY-50856R', 'NSC763371', 'NSC800874', 's1378', 'AKOS016842401', 'BCP9000784', 'CCG-264889', 'CS-0864', 'DB08877', 'FR27771', 'NSC-763371', 'NSC-800874', 'SDCCGSBI-0654261.P002', 'NCGC00244253-01', 'NCGC00244253-02', 'NCGC00244253-11', 'NCGC00244253-12', 'NCGC00244253-23', 'AC-24280', 'AC-38227', 'AS-18619', 'HY-50856', 'D09959', 'AB01565782_02', 'EN300-18772174', 'Q7383611', 'BRD-K53972329-001-02-1', 'BRD-K53972329-001-03-9', 'BRD-K53972329-001-07-0', '(3R)-3-cyclopentyl-3-[4-(1H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile', '(R)-3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H -pyrazol-1-yl)-3-cyclopentylpropanenitrile', '3-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-(beta-R)-1H-pyrazole-1-propanenitrile', 'A-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-(AR)-1H-pyrazole-1-propanenitrile', '(?-R)-?-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile;INCB 018424', '1H-PYRAZOLE-1-PROPANENITRILE, .BETA.-CYCLOPENTYL-4-(7H-PYRROLO(2,3-D)PYRIMIDIN-4-YL)-, (.BETA.R)-']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Staurosporine","PubChemCID":"44259","SMILES":"C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC","Synonyms":"['staurosporine', 'Staurosporin', 'Antibiotic 230', 'Antibiotic AM 2282', 'CCRIS 3272', 'Alkaloid AM-2282 from Streptomyces', 'AM-2282', 'H88EPA0A3N', 'DTXSID6041131', 'CHEBI:15738', 'Antibiotic AM-2282', 'STAUROSPORINE [MI]', '8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-', 'CGP-39360', '(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one', '(5S,6R,7R,9R)-6-methoxy-5-methyl-7-methylamino-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one', \"9,13-Epoxy-1H,9H-diindolo(1,2,3-gh:3',2',1'-lm)pyrrolo(3,4-j)(1,7)-benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, (9S-(9alpha,10beta,11beta,13alpha)-\", '(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21,23,25-nonaen-16-one', 'NSC618487', '(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo(12.12.2.1^(2,6).0^(7,28).0^(8,13).0^(15,19).0^(20,27).0^(21,26))nonacosa-8,10,12,14(28),15(19),20(27),21,23,25-nonaen-16-one', '(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo(12.12.2.12,6.07,28.08,13.015,19.020,27.021,26)nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one', '(5S,6R,7R,9R)-6-methoxy-5-methyl-7-methylamino-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo(b,h)cyclonona(1,2,3,4-jkl)cyclopenta(e)-as-indacen-14-one', \"(9alpha,10beta,11beta,13alpha)-(+)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H-9H-diindolo(1,2,3-gh:3',2',1'-lm)pyrrolo(3,4-j)(1,7)benzodiazonin-1-one\", \"(9alpha,10beta,11beta,13alpha)-(+)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H-9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one\", '1-((2R,3S,4S,6S)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo(12.12.2.12,6.07,28.08,13.015,19.020,27.021,26)nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl)-1-methylurea', '1-[(2R,3S,4S,6S)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-1-methylurea', 'DTXCID201340061', \"(9s,10r,11r,13r)-2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1h,9h-diindolo(1,2,3-gh:3',2',1'-lm)pyrrolo(3,4-j)(1,7)benzodiazonin-1-one\", '(+)-Staurosporine', '(5S,6R,7R,9R)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-14-one', 'CHEMBL388978', 'UNII-H88EPA0A3N', 'GNF-PF-1389', 'methoxy-methyl-(methylamino)[?]one', 'SR-00000001485', 'Staurosporin, 4', '1nvr', '1stc', '1xbc', '1xjd', '1yhs', '2gcd', 'Staurosporine, 8', 'CGP 39360', 'Staurosporine & TNF', 'Staurosporine (GMP)', '1q3d', '1sm2', '2dq7', 'MolMap_000047', 'SCHEMBL8157', 'CBiol_001978', 'BSPBio_001146', 'GTPL346', 'BDBM2579', 'MEGxm0_000307', '1u59', 'BCPP000063', 'Bio1_000264', 'Bio1_000753', 'Bio1_001242', 'HMS1990J07', 'HMS3650B17', 'EX-A1777', 'AM2282', 'HY-15141G', 'NSC755774', 's1421', 'Staurosporin and Antibiotic AM-2282', 'AKOS015897119', 'AM 2282', 'AS27871', 'CCG-208052', 'DB02010', 'NSC-755774', 'QTL1_000078', 'NCGC00162400-01', 'NCGC00162400-02', 'NCGC00162400-03', 'NCGC00162400-04', 'NCGC00162400-05', 'NCGC00162400-06', 'NCGC00162400-09', 'AC-35765', 'HY-15141', 'NS00011817', 'Staurosporine & Tumor necrosis factor (TNF)', 'T4000', 'Q5957181', 'SR-00000001485-4', 'BRD-K17953061-001-02-8', 'BRD-K17953061-001-04-4', 'BRD-K17953061-001-05-1', 'BRD-K17953061-001-08-5', 'BRD-K17953061-001-10-1', 'BRD-K17953061-001-11-9', '(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one', '(5S,6R,7R,9R)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one', \"(9S,10R,11R,13R)- 2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO(1,2,3-GH:3',2',1'-LM)PYRROLO(3,4-J)(1,7)BENZODIAZONIN-1-ONE\", '109189-95-9', \"9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, (9S,10R,11R,13R)- & Tumor necrosis factor (TNF)\", \"9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, (9S,10R,11R,13R)- (9CI)\", \"9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, [9S-(9alpha,10beta,11beta,13alpha)]-\"]","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Ibrutinib","PubChemCID":"24821094","SMILES":"C=CC(=O)N1CCC[C@H](C1)N2C3=NC=NC(=C3C(=N2)C4=CC=C(C=C4)OC5=CC=CC=C5)N","Synonyms":"['Ibrutinib', '936563-96-1', 'CRA-032765', 'ibrutinibum', 'Pc-32765', 'UNII-1X70OSD4VX', '1X70OSD4VX', 'JNJ 02', 'PCI-32765-00', 'CHEBI:76612', 'CRA 032765', '1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one', 'HSDB 8260', 'DTXSID60893450', '2-Propen-1-one, 1-((3R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo(3,4-d)pyrimidin-1-yl)-1-piperidinyl)-', '1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one', '1-((3R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo(3,4-d)pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one', 'L01XE27', 'DTXCID601323465', 'PCI-32765', 'IMBRUVICA', 'Ibrutinib (PCI-32765)', 'PCI 32765', '(R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one', 'PCI32765', 'C25H24N6O2', 'PCI-32765 (Ibrutinib)', '1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one', '(R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one.', '1-((3R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo(3,4-d)pyrimidin-1-yl)piperidin-1- yl)prop-2-en-1-one', 'Ibrutinib [USAN]', 'Ibrutinib [USAN:INN]', 'Imbruvica (TN)', '1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl]-2-propen-1-one;PCI 32765', '1-{(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1- yl}prop-2-en-1-one', 'MFCD20261150', 'Ibrutinib (Standard)', 'Ibrutinib, Free Base', 'IBRUTINIB [INN]', 'IBRUTINIB [JAN]', 'IBRUTINIB [MI]', 'Ibrutinib (JAN/USAN)', 'IBRUTINIB [VANDF]', 'IBRUTINIB [WHO-DD]', 'Imbruvica; PCI-32765', 'MLS006010041', 'SCHEMBL201859', 'Ibrutinib - Bio-X trade mark', 'GTPL6912', 'PCI-32765 (Ibrutinib)?', 'IBRUTINIB [ORANGE BOOK]', 'CHEMBL1873475', 'EX-A066', 'XYFPWWZEPKGCCK-GOSISDBHSA-N', 'BDBM50357312', 'HY-10997R', 'NSC800769', 'AKOS022185476', 'DB09053', 'EX-5960', 'FA34130', 'NSC-800769', 'NCGC00187912-01', 'NCGC00187912-02', 'NCGC00187912-03', 'NCGC00187912-12', 'NCGC00187912-17', 'NCGC00187912-18', '(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo-[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one', 'AC-26942', 'BI164531', 'HY-10997', 'SMR004701213', 'NS00072153', 'SW218096-2', 'EN300-97039', 'D10223', 'A1-01649', 'Q5984881', 'BRD-K70301465-001-02-6', 'BRD-K70301465-001-05-9', 'Z1302446275', '(R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-ylprop-2-en-1-one', '1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"PF3758309","PubChemCID":"25227462","SMILES":"CC1=NC2=C(C(=N1)NC3=NNC4=C3CN(C4(C)C)C(=O)N[C@H](CN(C)C)C5=CC=CC=C5)SC=C2","Synonyms":"['PF-3758309', '898044-15-0', 'PF-03758309', 'PK459EA5I2', 'example 114 [US8530652]', 'N-((1S)-2-(Dimethylamino)-1-phenylethyl)-6,6-dimethyl-3-((2-methylthieno(3,2-d)pyrimidin-4-yl)amino)-4,6-dihydropyrrolo(3,4-C)pyrazole-5(1H)-carboxamide', 'PF3758309', 'N-[(1S)-2-(dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]-1,4-dihydropyrrolo[3,4-c]pyrazole-5-carboxamide', 'compound 1 [PMID: 24432870]', 'example 114 (US8530652)', 'compound 1 (PMID: 24432870)', 'PF 3758309', 'N-((1S)-2-(dimethylamino)-1-phenylethyl)-6,6-dimethyl-3-((2-methylthieno(3,2-d)pyrimidin-4-yl)amino)-1,4-dihydropyrrolo(3,4-c)pyrazole-5-carboxamide', 'n-[(1S)-2-(dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1h)-carboxamide', 'N-((1S)-2-(dimethylamino)-1-phenylethyl)-6,6-dimethyl-3-((2-methylthieno(3,2-d)pyrimidin-4-yl)amino)-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazole-5-carboxamide', 'N-[(1S)-2-(dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-({2-methylthieno[3,2-d]pyrimidin-4-yl}amino)-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-5-carboxamide', '(S)-N-(2-(dimethylamino)-1-phenylethyl)-6,6-dimethyl-3-((2-methylthieno[3,2-d]pyrimidin-4-yl)amino)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxamide', 'CHEMBL3128043', '898044-15-0 (free base)', '(S)-N-(2-(DIMETHYLAMINO)-1-PHENYLETHYL)-6,6-DIMETHYL-3-((2-METHYLTHIENO[3,2-D]PYRIMIDIN-4-YL)AMINO)-4,6-DIHYDROPYRROLO[3,4-C]PYRAZOLE-5(1H)-CARBOXAMIDE.', 'US8530652, 114', 'UNII-PK459EA5I2', '7KC', 'MFCD18633226', 'GTPL8937', 'SCHEMBL1369342', 'CHEBI:93751', 'DTXSID70649389', 'EX-A849', 'BDBM101536', 'BDBM101618', 'BCP08233', 'Pyrrolo[3,4-c]pyrazole-5(1H)-carboxaMide, N-[(1S)-2-(diMethylaMino)-1-phenylethyl]-4,6-dihydro-6,6-diMethyl-3-[(2-Methylthieno[3,2-d]pyriMidin-4-yl)aMino]-', 'YKB04415', 'NSC781470', 'NSC800847', 's7094', 'AKOS027422746', 'CCG-269617', 'CS-0773', 'DB11775', 'NSC-781470', 'NSC-800847', 'NCGC00345784-01', 'NCGC00345784-03', 'NCGC00345784-05', '(S)-N-(2-(Dimethylamino)-1-phenylethyl)-6,6-dimethyl-3-((2-methylthieno[3,2-d]pyrimidin-4-yl)amino)-', 'AC-33020', 'AS-56208', 'HY-13007', 'NS00072558', 'SW219931-1', 'PF03758309 pound>>PF 03758309', 'PF 3758309; PF3758309', 'PF-3758309;cas:898044-15-0', 'BRD-K37764012-001-04-1', 'Q27088331', '(S)-N-(2-(Dimethylamino)-1-phenylethyl)-6,6-dimethyl-3-((2-methylthieno[3,2-d]pyrimidin-4-yl)amino)-2,6-dihydropyrrolo[3,4-c]pyrazole-5(4H)-carboxamide', '(S)-N-(2-(Dimethylamino)-1-phenylethyl)-6,6-dimethyl-3-(2-methylthieno[3,2-d]pyrimidin-4-ylamino)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxamide', '1279200-38-2', 'N-[(1S)-2-(dimethylamino)-1-phenylethyl]-6,6-dimethyl-3-({2-methylthieno[3,2-d]pyrimidin-4-yl}amino)-1H,4H-pyrrolo[3,4-c]pyrazole-5-carboxamide']","Type":"small molecule"},{"Action":"cytotoxic","PerturbationName":"Ipi145","PubChemCID":"50905713","SMILES":"C[C@@H](C1=CC2=C(C(=CC=C2)Cl)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5","Synonyms":"['Duvelisib', 'IPI-145', 'INK-1197', 'UNII-610V23S0JI', '(S)-3-(1-(9H-purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one', '610V23S0JI', 'INK-1147', '1(2H)-Isoquinolinone, 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-', 'DTXSID80152697', '8-chloro-2-phenyl-3-((1S)-1-(9H-purin-6-ylamino)ethyl)-1(2H)-isoquinolinone', '1(2H)-Isoquinolinone, 8-chloro-2-phenyl-3-((1S)-1-(9H-purin-6-ylamino)ethyl)-', '8-Chloro-2-phenyl-3-((1S)-1-(7H-purin-6-ylamino)ethyl)isoquinolin-1(2H)-one', 'compound 4904 (Patent US8193182)', 'compound 4904 [Patent US8193182]', 'duvelisibum', 'DTXCID2075188', '1201438-56-3', '(S)-3-(1-((9H-Purin-6-yl)amino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one', 'IPI 145', 'IPI145', 'Duvelisib (IPI-145, INK1197)', '8-chloro-2-phenyl-3-[(1S)-1-(7H-purin-6-ylamino)ethyl]isoquinolin-1-one', 'Duvelisib [USAN]', 'Duvelisib [USAN:INN]', 'IPI-145 (INK1197)', 'IPI-145;INK1197', 'MFCD15144635', 'DUVELISIB [INN]', 'DUVELISIB [MI]', 'Duvelisib (USAN/INN)', 'Duvelisib (IPI-145)', 'DUVELISIB [WHO-DD]', 'SCHEMBL153543', 'GTPL7795', 'DUVELISIB [ORANGE BOOK]', 'CHEMBL3039502', 'SCHEMBL18343557', 'SCHEMBL19670020', 'SCHEMBL20580104', 'CHEBI:131169', 'SJVQHLPISAIATJ-ZDUSSCGKSA-N', 'BCP07042', 'EX-A1562', 'BDBM50193013', 'NSC772469', 's7028', 'AKOS022186370', 'AKOS037515795', 'IPI-145, INK 1197, Duvelisib', 'CCG-268854', 'CS-0888', 'DB11952', 'FP43074', 'NSC-772469', 'Duvelisib (IPI-145, INK1197)?', 'NCGC00351482-01', 'NCGC00351482-12', 'AC-30239', 'AS-16309', 'HY-17044', 'NS00073044', 'SW219822-1', 'D10555', 'EN300-18167128', 'BRD-K93468883-001-02-0', 'Q27077129', 'IPI-145 pound>>INK1197; IPI 145; IPI145; INK-1197; INK 1197', '8-chloro-2-phenyl-3-[(1S)-1-[(9H-purin-6-yl)amino]ethyl]-1,2-dihydroisoquinolin-1-one', '8-Chloro-2-phenyl-3-[(1S)-1-[(9H-purin-6-yl)amino]ethyl]isoquinolin-1-one', 'INK1197;(S)-3-(1-(9H-Purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one;Duvelisib']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Tretinoin","PubChemCID":"444795","SMILES":"CC1=C(C(CCC1)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/C","Synonyms":"['tretinoin', 'ATRA', 'Renova', 'Aknefug', 'Atralin', 'Retin-A Micro', 'Tretinoina', 'Effederm', 'Avita', 'Tretinoino', 'Tretinoinum', 'Aberela', 'Acnavit', 'Avitoin', 'A-Vitaminsyre', 'Kerlocal', 'Oristar rna', 'Tretinoine [INN-French]', 'Tretinoinum [INN-Latin]', 'Tretinoina [INN-Spanish]', 'Tretinoino [INN-Spanish]', 'CCRIS 3294', 'HSDB 2169', 'EINECS 206-129-0', 'NSC 122758', 'UNII-5688UTC01R', 'ALTRENO', 'BRN 2057223', '5688UTC01R', 'Renova (0.02% cream)', 'Altreno (0.05% lotion)', 'Avita (0.025% gel)', 'ZIANA COMPONENT TRETINOIN', 'SOLAGE COMPONENT TRETINOIN', 'TWYNEO COMPONENT TRETINOIN', 'VELTIN COMPONENT TRETINOIN', 'Tretinoin [USAN:USP:INN:BAN]', 'TRI-LUMA COMPONENT TRETINOIN', 'Tretinoine (INN-French)', 'Tretinoinum (INN-Latin)', 'Tretinoina (INN-Spanish)', 'Tretinoino (INN-Spanish)', 'TRETINOIN (MART.)', 'TRETINOIN [MART.]', 'TRETINOIN (USP-RS)', 'TRETINOIN [USP-RS]', 'TRETINOIN (EP MONOGRAPH)', 'TRETINOIN [EP MONOGRAPH]', 'TRETINOIN (USP MONOGRAPH)', 'TRETINOIN [USP MONOGRAPH]', 'Tretinoin (USAN:USP:INN:BAN)', 'ISOTRETINOIN IMPURITY A (EP IMPURITY)', 'ISOTRETINOIN IMPURITY A [EP IMPURITY]', 'Tretinoin Cream', 'RETIN-A-MICRO', 'D10AD01', 'L01XX14', 'TRETINOIN COMPONENT OF ZIANA', 'TRETINOIN COMPONENT OF SOLAGE', 'TRETINOIN COMPONENT OF TWYNEO', 'TRETINOIN COMPONENT OF VELTIN', 'TRETINOIN COMPONENT OF TRI-LUMA', '206-129-0', 'Retinoic acid', '302-79-4', 'all-trans-Retinoic acid', 'Vitamin A acid', 'trans-Retinoic acid', 'Retin-A', 'Vesanoid', 'Aberel', 'Eudyna', 'Airol', 'All-trans Retinoic Acid', 'all-trans-Vitamin A acid', 'Dermairol', 'Aknoten', 'TRETINON', 'Cordes vas', 'Epi-aberel', 'Tretin M', 'Retin A', 'all-trans-Vitamin A1 acid', 'all-trans-Tretinoin', 'Retionic acid', 'All Trans Retinoic Acid', 'Vitamin A1 acid, all-trans-', 'beta-Retinoic acid', 'all-(E)-Retinoic acid', 'Vitamin A acid, all-trans-', 'Tretinoine', '(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid', 'Retinoic acid, all-trans-', 'Alltrans-retinoic acid', 'NSC-122758', 'Retinoate', 'Retacnyl', 'Vesnaroid', 'Ro 1-5488', 'Tretinoin, all-trans-', 'all trans-Retinoic acid', 'Stieva-A', 'all-trans-beta-Retinoic acid', '.beta.-Retinoic acid', 'RETINOIC ACID, ALL TRANS', 'Tretinoin/All-Trans Retinoic Acid', 'Aberela [Norway]', 'Avitoin [Norway]', 'Effederm [France]', '(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid', 'MFCD00001551', 'A-Acido (Argentina)', '3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid', 'MLS000028588', 'b-Retinoic acid', 'DTXSID7021239', 'Retinoic acid (GMP)', 'AT-RA', 'CHEMBL38', '(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid', '2,4,6,8-Nonatetraenoic acid, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-', 'NSC122758', 'Atragen', 'Retinova', 'SMR000058245', '(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoic acid', 'CHEBI:15367', '15-Apo-beta-caroten-15-oic acid', 'Tretinoin (TN)', 'beta-Ra', 'Acnavit [Denmark]', 'AGN 100335', 'Retin A (TN)', 'NCGC00017280-10', 'Betarretin', 'all-trans-b-Retinoic acid', 'Cordes VAS [Germany]', 'A-Vitaminsyre [Denmark]', '3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid (ECL)', 'trans-Retinoate', 'beta-Retinoate', 'DTXCID001239', 'tretinoine (French) (EINECS)', 'cis-Retinoic acid', 'Acide retinoique (French) (DSL)', 'Refissa', 'Nexret', 'Vitamin a acid, trans-', 'Retisol-A', 'Acid A Vit (Belgium, Netherlands)', '3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2E,4E,6E,8E-tetraenoic acid', '97950-17-9', 'Isotretinoin;(2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid', '[3H]Retinoic acid', 'Renova (TN)', 'Avita (TN)', 'SR-01000000239', 'retinoicacid', 'Tretinoin (JAN/USP/INN)', 'Tretinion', 'TNP00194', 'BML2-E05', 'Vitamine A acid', '1cbr', '[3H]tretinoin', '[All-E]-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid', '(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid', 'CAS-302-79-4', 'Tretinoin; (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoic acid; Retinoic acid; Isotretinoin Impurity A', 'Prestwick_424', 'all-(E)-Retinoate', 'Tretinoine (French)', 'Retinoic acid, cis-', '[3H]Vitamin A acid', 'RETINOL_met006', '1n4h', 'CPD000058245', 'Retinoic acid all trans', 'TRETINOIN [INN]', 'TRETINOIN [JAN]', 'TRETINOIN [HSDB]', 'TRETINOIN [USAN]', 'Vitamin-A-sA currencyure', 'Opera_ID_1055', 'Prestwick2_000257', 'Prestwick3_000257', 'Spectrum5_001746', 'Spectrum5_001933', 'Retinoic acid (Standard)', 'TRETINOIN [VANDF]', 'acide retinoique (French)', 'Vesanoid (TN) (Roche)', 'bmse000562', 'UPCMLD-DP097', 'R 2625', 'RETINOIC ACID [MI]', 'SCHEMBL3145', 'TRETINOIN [WHO-DD]', '3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-all-trans-tetraenoic acid', 'BIDD:PXR0081', 'Lopac0_001061', 'BSPBio_000074', 'BSPBio_001500', 'MLS001076515', 'MLS002207234', 'MLS002222211', 'MLS002548861', 'MLS006010222', 'BIDD:GT0483', 'SPECTRUM1502016', '9-cis-retinoic acid (9cRA)', 'Tretinoin - Bio-X trade mark', 'LGD 1057; NSC 659772; Panretin; Panretyn; Panrexin; Toctino', '[3H]RA', 'BPBio1_000082', 'cid_444795', 'GTPL2644', '.beta.-all-trans-Retinoic acid', 'TRETINOIN [ORANGE BOOK]', 'all-trans-retinoic acid (ATRA)', 'BDBM31883', 'HMS502N05', 'all-trans-Retinoic acid/Tretinoin', 'BCPP000036', 'BDBM323588', 'HMS1361K22', 'HMS1568D16', 'HMS1791K22', 'HMS1921D14', 'HMS1989K22', 'HMS2089D20', 'HMS2092N11', 'HMS2095D16', 'HMS2236N03', 'HMS3259E11', 'HMS3263E04', 'HMS3402K22', 'HMS3411B09', 'HMS3675B09', 'HMS3712D16', 'Pharmakon1600-01502016', 'Retinoic acid, all-trans- (8CI)', 'BCP01405', 'US10188615, at-RA', 'Tox21_110812', 'Tox21_202330', 'Tox21_300305', 'Tox21_501061', 'All-trans Retinoic Acid (Tretinoin)', 'CCG-39912', 'HY-14649G', 'HY-14649R', 'LMPR01090019', 'NSC759631', 's1653', 'AKOS000280845', 'Tox21_110812_1', 'AC-6824', 'CS-1269', 'DB00755', 'FR17921', 'GS-3578', 'LP01061', 'NC00481', 'NSC-759631', 'SDCCGSBI-0051031.P004', '3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid', 'IDI1_000903', 'IDI1_033970', 'NCGC00017280-05', 'NCGC00017280-06', 'NCGC00017280-07', 'NCGC00017280-08', 'NCGC00017280-09', 'NCGC00017280-12', 'NCGC00017280-15', 'NCGC00017280-16', 'NCGC00017280-17', 'NCGC00017280-18', 'NCGC00017280-19', 'NCGC00017280-20', 'NCGC00017280-23', 'NCGC00017280-38', 'NCGC00021808-04', 'NCGC00021808-05', 'NCGC00021808-06', 'NCGC00021808-07', 'NCGC00021808-09', 'NCGC00021808-11', 'NCGC00021808-14', 'NCGC00021808-15', 'NCGC00254179-01', 'NCGC00259879-01', 'NCGC00261746-01', 'BP-20401', 'BR164493', 'HY-14649', 'Retinoic acid, >=98% (HPLC), powder', 'SBI-0051031.P003', 'CS-0626116', 'EU-0101061', 'R0064', 'SW203749-4', 'C00777', 'D00094', 'Q29417', 'AB00052318-15', 'AB00052318-16', 'AB00052318-17', 'AB00052318_18', 'AB00052318_19', 'EN300-27107561', 'L000833', 'SR-01000000239-3', 'SR-01000000239-4', 'SR-01000000239-6', 'SR-01000000239-7', 'BRD-K06926592-001-01-7', 'BRD-K71879491-001-15-0', 'BRD-K71879491-001-22-6', 'BRD-K71879491-001-37-4', 'BRD-K71879491-001-38-2', 'BRD-K71879491-001-39-0', 'BRD-K71879491-001-44-0', 'BRD-K71879491-001-47-3', 'BRD-K71879491-001-48-1', 'SR-01000000239-12', 'SR-01000000239-13', 'SR-01000000239-14', 'SR-01000000239-15', 'WLN: L6UTJ A1 B1U1Y1&U2U1Y1&U1VQ C1 C1', 'Tretinoin, European Pharmacopoeia (EP) Reference Standard', 'WLN: L6UTJ A1 B1U1Y1 & U2U1Y1 & U1VQ C1 C1', 'Tretinoin, United States Pharmacopeia (USP) Reference Standard', '3,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid', 'Tretinoin, Pharmaceutical Secondary Standard; Certified Reference Material', '(8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid', '(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoate', '2,4,6,8-Nonatetranoic acid, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-', '2,6,8-Nonatetranoic acid, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-', '3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoate', 'all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid', '(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid;all-trans-Retinoic acid;ATRA', '(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid;Tretinoin;ATRA', '2,4, 6,8-Nonatetranoic acid, 3,7-dimethyl-9-(2,6, 6-trimethyl-1-cyclohexen-1-yl)-, (2E, 4E, 6E, 8E)-', '2,4,6,8-Nonatetraenoic acid, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)--, (all trans)-', '2,4,6,8-Nonatetranoic acid, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all trans)-', '2,6,8-Nonatetraenoic acid, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-', '3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid-, (all trans)-']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Olaparib","PubChemCID":"23725625","SMILES":"C1CC1C(=O)N2CCN(CC2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F","Synonyms":"['Olaparib', '763113-22-0', 'AZD2281', 'Lynparza', 'KU-0059436', 'AZD-2281', 'AZD 2281', 'OLAPARIB cpd', 'KU-59436', 'UNII-WOH1JD9AR8', 'WOH1JD9AR8', 'Olaparibum', 'AZ2281', 'NSC-747856', 'AZD221', 'CHEBI:83766', 'AZ-2281', 'KEYLYNK-010 COMPONENT OLAPARIB', 'KU59436', 'KU 59436', '4-(3-{[4-(Cyclopropylcarbonyl)piperazin-1-Yl]carbonyl}-4-Fluorobenzyl)phthalazin-1(2h)-One', 'NSC 747856', 'OLAPARIB COMPONENT OF KEYLYNK-010', 'OLAPARIB (MART.)', 'OLAPARIB [MART.]', '(2H)-Phthalazinone, 4-((3-((4-(cyclopropylcarbonyl)-1-piperazinyl)carbonyl)-4-fluorophenyl)methyl)-', '1(2H)-Phthalazinone, 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-', '4-[(3-{[4-(Cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorophenyl)methyl]phthalazin-1(2H)-one', 'PIPERAZINE, 1-(CYCLOPROPYLCARBONYL)-4-(5-((3,4-DIHYDRO-4-OXO-1-PHTHALAZINYL)METHYL)-2-FLUOROBENZOYL)-', '4-(3-((4-(cyclopropylcarbonyl)piperazin-1-yl)carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one', '1(2H)-PHTHALAZINONE, 4-((3-((4-(CYCLOPROPYLCARBONYL)-1-PIPERAZINYL)CARBONYL)-4-FLUOROPHENYL)METHYL)-', '4-((3-((4-(CYCLOPROPYLCARBONYL)PIPERAZIN-1-YL)CARBONYL)-4-FLUOROPHENYL)METHYL)PHTHALAZIN-1(2H)-ONE', '4-((3-{(4-(cyclopropylcarbonyl)piperazin-1-yl)carbonyl}-4-fluorophenyl)methyl)phthalazin-1(2H)-one', 'PARP inhibitor AZD2281', 'L01XX46', '1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine', '4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one', 'Olaparib (AZD2281, Ku-0059436)', 'Olaparib (AZD-2281)', 'Olaparib [USAN:INN]', 'MFCD13185161', '4-[[3-[4-(Cyclopropanecarbonyl)piperazine-1-carbonyl]-4-fluorophenyl]methyl]-2H-phthalazin-1-one', '4-[3-(4-Cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one', 'Olaparib (DISCONTINUED)', '4-[3-[4-(Cyclopropanecarbonyl)piperazine-1-carbonyl]-4-fluorobenzyl]phthalazin-1(2H)-one', 'Olaparib [INN]', 'Olaparib (AZD2281; Ku-0059436)', 'C24H23FN4O3', 'Olaparib (AZD2281)', 'Olaparib, KU-0059436', '937799-91-2', 'Lynparza (TN)', '09L', '4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone; AZD 2281; KU 0059436; KU 59436; 1-(Cyclopropylcarbonyl)-4-[5-[(3,4-dihydro-4-oxo-1-phthalazinyl)methyl]-2-fluorobenzoyl]piperazine;', 'Olaparib (Standard)', 'AZD2281(olaparib)', 'OLAPARIB [USAN]', 'OLAPARIB [JAN]', 'OLAPARIB [MI]', 'OLAPARIB [VANDF]', 'OLAPARIB [WHO-DD]', 'Olaparib (JAN/USAN/INN)', 'AZD-2281 (Olaparib)?', 'MLS006010185', 'Olaparib - Bio-X trade mark', 'SCHEMBL426568', 'OLAPARIB [ORANGE BOOK]', 'CHEMBL521686', 'GTPL7519', 'BDBM27566', 'DTXSID60917988', 'EX-A002', 'FDLYAMZZIXQODN-UHFFFAOYSA-N', 'BCPP000360', 'GLXC-02796', 'HMS3295I09', 'HMS3426C03', 'HMS3654G13', 'HMS3746K07', 'HMS3870H03', 'BCP01872', '763113-22-0, Lynparza,', 'HY-10162R', 'NSC747856', 'NSC753686', 's1060', 'AKOS005145764', 'AC-7939', 'BCP9000363', 'CCG-264799', 'CS-0075', 'DB09074', 'EX-7210', 'FO33122', 'NSC-753686', 'SB14617', 'SS-4573', 'AZD2281,Olaparib, KU-0059436', 'NCGC00238451-01', 'NCGC00238451-02', 'NCGC00238451-08', 'NCGC00238451-09', 'NCGC00238451-11', '4-[(3-{[4-Cyclopropylcarbonyl)piperazin-4-yl]carbonyl}-4-fluorophenyl)methyl]phtalazin-1(2H)-one', '4-[[3-[[4-(Cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone', '4-{[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one', 'BO164169', 'HY-10162', 'SMR004701291', 'SY040527', 'NS00072449', 'SW218142-2', 'D09730', 'EN300-7542225', 'Q7083106', 'BRD-K02113016-001-08-9', 'BRD-K02113016-001-09-7', 'BRD-K02113016-001-15-4', 'BRD-K02113016-001-19-6', 'Z2227698469', '1021843-02-6', '4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbonyl]-4-fluorophenyl}methyl)-1,2-dihydrophthalazin-1-one']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"KN93","PubChemCID":"5312122","SMILES":"CN(C/C=C/C1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC","Synonyms":"['kn-93', '139298-40-1', 'KN 93', '2TW744QBU1', 'UNII-2TW744QBU1', '2-(N-(2-Hydroxyethyl)-N-(4-methoxybenzenesulfonyl))amino-N-(4-chlorocinnamyl)-N-methylbenzylamine', 'CHEBI:91460', 'Benzenesulfonamide, N-(2-(((3-(4-chlorophenyl)-2-propenyl)methylamino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxy-', 'Benzenesulfonamide, N-[2-[[[3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-', 'N-(2-(((3-(4-Chlorophenyl)-2-propenyl)methylamino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide', '2-(N-(2-HYDROXYETHYL))-N-(4-METHOXYBENZENESULFONYL))AMINO-N-(4-CHLOROCINNAMYL)-N-METHYLBENZYLAMINE', 'BENZENESULFONAMIDE, N-(2-(((3-(4-CHLOROPHENYL)-2-PROPEN-1-YL)METHYLAMINO)METHYL)PHENYL)-N-(2-HYDROXYETHYL)-4-METHOXY-', \"N-[2-({[(2E)-3-(4-chlorophenyl)prop-2-en-1-yl](methyl)amino}methyl)phenyl]-2-hydroxy-S'-(4-methoxyphenyl)ethane-1-sulfonamido\", 'N-[2-({[(2E)-3-(4-chlorophenyl)prop-2-en-1-yl](methyl)amino}methyl)phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide', 'N-[2-[[[3-(4-chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide', 'N-[2-[[3-(4-chlorophenyl)prop-2-enyl-methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide', '2-[N-(2-hydroxyethyl)]-N-(4-methoxybenzenesulfonyl)]amino-N-(4-chlorocinnamyl)-N-methylbenzylamine', \"N-(2-((((2E)-3-(4-chlorophenyl)prop-2-en-1-yl)(methyl)amino)methyl)phenyl)-2-hydroxy-S'-(4-methoxyphenyl)ethane-1-sulfonamido\", 'N-(2-((((2E)-3-(4-chlorophenyl)prop-2-en-1-yl)(methyl)amino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide', 'N-(2-((3-(4-chlorophenyl)prop-2-enyl-methylamino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide', 'Methoxybenzene-sulfonamide', 'KN93', '(E)-N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide', '1188890-40-5', 'N-[2-[[[(E)-3-(4-chlorophenyl)prop-2-enyl]-methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide', 'CHEMBL155333', \"N-[2-[[[3-(4'-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4'-methoxybenzenesulfonamide\", 'N-(2-(((3-(4-CHLOROPHENYL)-2-PROPEN-1-YL)METHYLAMINO)METHYL)PHENYL)-N-(2-HYDROXYETHYL)-4-METHOXYBENZENESULFONAMIDE', 'N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide', 'N-[2-[[[3-(4-Chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide', 'N-[2-[[[3-(4-Chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide;', 'MFCD00236424', 'KN-93(free base)?', 'BiomolKI_000041', 'BiomolKI2_000049', 'BMK1-E5', 'GTPL6002', 'SCHEMBL1983199', 'LLLQTDSSHZREGW-AATRIKPKSA-N', 'BCPP000193', 'GLXC-03438', 'HMS3229K12', 'HMS3648M10', 'EX-A2884', 'N-[2-[N-(4-Chlorocinnamyl)-N-methylaminomethyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide', 'BDBM50108799', 'FD5004', 'HSCI1_000371', 'MFCD03788201', 's6787', 'AKOS015994570', 'BCP9000817', 'CCG-100645', 'CS-1095', 'ES-0019', 'FK24812', 'SDCCGSBI-0086770.P004', 'NCGC00162399-02', 'NCGC00162399-04', 'HY-15465', 'SR-01000946389', 'KN-93 - CAS 139298-40-1', 'SR-01000946389-1', 'BRD-K93480852-001-03-0', 'BRD-K93480852-001-05-5', 'BRD-K93480852-001-06-3', 'BRD-K93480852-003-01-0', '(2-[N -(2-hydroxyethyl)]-N -(4-methoxybenzenesulfonyl)]amino-N -(4-chlorocinnamyl)-N -methylbenzylamine)', 'N-(2-(((4-chlorocinnamyl)(methyl)amino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide', 'N-[2-({[(2E)-3-(4-chlorophenyl)prop-2-en-1-yl](methyl)amino}methyl)phenyl]-N-(2-hydroxyethyl)-4-methoxybenzene-1-sulfonamide', 'N-[2-({[3-(4-Chloro-phenyl)-allyl]-methyl-amino}-methyl)-phenyl]-N-(2-hydroxy-ethyl)-4-methoxy-benzenesulfonamide', \"n-[2-[[[3-(4'-chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-n-(2-hydroxyethyl)-4'-methoxybenzenesulfonamide phosphate salt\", 'N-[2-[N-(4-Chlorocinnamyl)-N-methylaminomethyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide phosphate salt']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Linsitinib","PubChemCID":"11640390","SMILES":"CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O","Synonyms":"['Linsitinib', '867160-71-2', 'OSI-906', 'OSI906', 'OSI 906', 'OSI-906AA', 'ASP-7487', 'Linsitinib [USAN]', 'Linsitinib [USAN:INN]', '15A52GPT8T', 'LINSITINIB [INN]', 'LINSITINIB [WHO-DD]', 'DTXSID401007055', 'cis-3-(8-amino-1-(2-phenyl-7-quinolinyl)imidazo(1,5-a)pyrazin-3-yl)-1-methylcyclobutanol', 'Cis-3-(8-Amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutan-1-ol', 'cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol', 'CIS-3-(8-AMINO-1-(2-PHENYLQUINOLIN-7-YL)IMIDAZO(1,5-A)PYRAZIN-3-YL)-1-METHYLCYCLOBUTAN-1-OL', 'CYCLOBUTANOL, 3-(8-AMINO-1-(2-PHENYL-7-QUINOLINYL)IMIDAZO(1,5-A)PYRAZIN-3-YL)-1-METHYL-, CIS-', 'linsitinibum', 'cis-3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol', '(1s,3r)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo(1,5-a)pyrazin-3-yl)-1-methylcyclobutan-1-ol', '(1s,3r)-3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol', 'CIS-3-(8-AMINO-1-(2-PHENYLQUINOLIN-7-YL)IMIDAZO(1,5-A)PYRAZIN-3-YL)-1-METHYLCYCLOBUTANOL', 'Cyclobutanol, 3-(8-amino-1-(2-phenyl-7-quinolinyl)imidazo(1,5-a)pyrazin-3-yl)-1-methyl, cis-', 'Cyclobutanol, 3-[8-amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl, cis-', 'IGF-1R inhibitor OSI-906', 'DTXCID201509855', 'OSI-906 (Linsitinib)', 'Linsitinib(OSI-906)', '3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol', 'CHEMBL1091644', 'MMV676605', '(1r,3r)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutanol.', 'Kinome_3532', 'UNII-15A52GPT8T', 'C26H23N5O', 'MFCD12912153', 'Linsitinib; OSI-906', 'Linsitinib (USAN/INN)', 'Linsitinib (OSI-906)', 'Linsitinib(OSI-906)?', 'MLS006010304', 'SCHEMBL400369', 'SCHEMBL400734', 'SCHEMBL400735', 'GTPL7423', 'CHEMBL1996234', 'SCHEMBL10255925', 'CHEBI:91402', 'EX-A719', 'BCPP000137', 'BDBM185150', 'DTXSID901121553', 'HMS3295G15', 'HMS3654C19', 'BCP01831', 'BDBM50315887', 'NSC756652', 'NSC800784', 's1091', 'AKOS024464740', 'BCP9001035', 'CCG-264815', 'CS-0242', 'DB06075', 'FO65116', 'NSC-756652', 'NSC-800784', 'PB22643', 'SDCCGSBI-0646932.P001', 'NCGC00250375-02', 'NCGC00250375-03', 'NCGC00250375-11', 'NCGC00250375-14', '(1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutan-1-ol', '(1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutanol', 'AC-26953', 'AS-16999', 'HY-10191', 'SMR004700744', 'NS00073285', 'SW218150-2', 'D09925', 'SR-05000022538', 'Q6554803', 'SR-05000022538-1', 'BRD-K07667918-001-01-3', 'BRD-K86118762-001-01-8', 'BRD-K86118762-001-05-9', 'Q27163260', '3-[8-amino-1-(2-phenyl-7-quinolinyl)-3-imidazo[1,5-a]pyrazinyl]-1-methyl-1-cyclobutanol', '(1R,3S)-3-[8-AMINO-1-(2-PHENYLQUINOLIN-7-YL)IMIDAZO[1,5-A]PYRAZIN-3-YL]-1-METHYLCYCLOBUTAN-1-OL', '1356958-77-4', '3-(8-amino-1-(2-phenylquinolin-7-yl)-2,3-dihydroimidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutanol', '3-[8-AMINO-1-(2-PHENYL-QUINOLIN-7-YL)-IMIDAZO[1,5-A]PYRAZIN-3-YL]-1-METHYL-CYCLOBUTANOL', '867160-72-3', 'cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol; OSI 906; OSI 906AA;', 'trans-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"AZD5438","PubChemCID":"16747683","SMILES":"CC1=NC=C(N1C(C)C)C2=NC(=NC=C2)NC3=CC=C(C=C3)S(=O)(=O)C","Synonyms":"['602306-29-6', 'AZD5438', 'AZD 5438', 'AZD-5438', '4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)-N-(4-(methylsulfonyl)phenyl)pyrimidin-2-amine', '4-(2-methyl-3-propan-2-ylimidazol-4-yl)-N-(4-methylsulfonylphenyl)pyrimidin-2-amine', 'CHEMBL488436', 'MMV676604', '276Z913G29', '4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{N}-(4-methylsulfonylphenyl)pyrimidin-2-amine', '4-(3-isopropyl-2-methylimidazol-4-yl)-N-(4-methanesulfonylphenyl)pyrimidin-2-amine', '4-(1-isopropyl-2-methyl-1h-imidazol-5-yl)-N-[4-(methylsulfonyl)phenyl]pyrimidin-2-amine', 'WJRRGYBTGDJBFX-UHFFFAOYSA-N', 'FB8', '4-[2-METHYL-1-ISOPROPYL-1H-IMIDAZOL-5-YL]-N-[4-(METHYLSULFONYL)PHENYL]-2-PYRIMIDINAMINE', 'MLS006011033', 'GTPL8473', 'SCHEMBL5092360', 'CHEBI:91419', 'EX-A069', 'BCPP000368', 'DTXSID501025680', 'GLXC-04428', 'HMS3295K15', 'HMS3656B05', 'HMS3750K15', 'UNII-276Z913G29', 'AZD5438?', 'BCP02271', 'AZD5438,AZD 5438', 'BDBM50246253', 'NSC799348', 's2621', 'AKOS005145565', 'BCP9000353', 'CCG-268315', 'EX-8669', 'NSC-799348', 'SB19462', 'SDCCGSBI-0654412.P001', 'NCGC00346617-01', 'NCGC00346617-09', 'AC-30292', 'AS-56007', 'FM137464', 'HY-10012', 'SMR004700644', 'SW219680-1', 'SR-05000022535', 'SR-05000022535-1', 'BRD-K72414522-001-02-6', 'BRD-K72414522-001-06-7', 'BRD-K72414522-001-08-3', 'BRD-K72414522-001-10-9', 'Q27074758', '4-(1-isopropyl-2-methylimidazol-5-yl)-2-(4-mesylanilino)pyrimidine', '4-(1-Isopropyl-2-methylimidazol-5-yl)-2-[4-(methylsulphonyl)anilino]pyrimidine', '2-Pyrimidinamine, 4-(2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl)-N-(4-     (methylsulfonyl)phenyl)-', '2-PYRIMIDINAMINE, 4-(2-METHYL-1-(1-METHYLETHYL)-1H-IMIDAZOL-5-YL)-N-(4-(METHYLSULFONYL)PHENYL)-', '4-(2-Methyl-1-(1-methylethyl)-1H-imidazol-5-yl)-N-(4- (methylsulfonyl)phenyl)-2-pyrimidinamine', '4-[2-Methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine and N-(4-(methylsulfonyl)phenyl)pyrimidin-2-amine']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Olmesartan","PubChemCID":"158781","SMILES":"CCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)O)C(C)(C)O","Synonyms":"['Olmesartan', '144689-24-7', 'RNH-6270', 'omesartan', 'RNH 6270', 'UNII-8W1IQP3U10', 'CS-088', 'NSC-759810', '8W1IQP3U10', 'CHEBI:48416', 'HSDB 8214', 'DTXSID2040571', 'EC 646-413-5', 'NSC 759810', \"1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-\", \"4-(hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylic acid\", \"(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylate\", \"4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid\", \"4-(hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid\", \"4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-carboxylic acid\", \"4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylic acid\", \"4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic acid\", 'DTXCID0020571', 'Olmesartan Acid', \"1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid\", \"1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-\", 'MFCD00914967', '5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid', 'CHEMBL1516', 'Votum', 'Olmesartan [USAN]', \"4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazole-5-carboxylic Acid (Olmesartan)\", \"4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid\", 'SMR000466337', 'Olmesartan [USAN:INN:BAN]', 'Benicar;Olmetec', 'OLM', 'Olmesartan medoximil', \"Olmesartan Medoxomil Imp. A (EP); 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazole-5-carboxylic Acid; Olmesartan; Olmesartan Acid; Olmesartan Medoxomil Impurity A\", 'OLMESARTAN [MI]', 'OLMESARTAN [INN]', 'Olmesartan (USAN/INN)', 'OLMESARTAN [VANDF]', 'OLMESARTAN [WHO-DD]', 'SCHEMBL94037', 'MLS000759446', 'MLS001424016', 'MLS006011945', 'Olmesartan, >=98% (HPLC)', 'GLXC-05183', 'HMS2051K12', 'HMS2235O24', 'HMS3369I09', 'HMS3393K12', 'HMS3604J06', 'Pharmakon1600-01505206', 'BCP12007', 'BDBM50241364', 'DE-092', 'NSC759810', 's5581', 'AKOS015900241', 'AKOS024458255', 'AC-9385', 'CCG-100868', 'CCG-269198', 'CS-0576', 'DB00275', 'IH57928', 'NC00118', 'NCGC00246968-01', 'NCGC00246968-02', 'NCGC00246968-04', '1ST10402', \"4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid\", '4-(2-hydroxypropan-2-yl)-2-propyl-1-({4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazole-5-carboxylic acid', 'AS-10242', 'HY-17004', 'Olmesartan medoxomil impurity, olmesartan-', 'SMR004703526', 'DB-042742', 'NS00008999', 'O0507', 'C21543', 'D05246', 'EN300-122328', 'L001097', 'Olmesartan 100 microg/mL in Acetonitrile:Methanol', 'Q421156', 'BRD-K83144676-001-06-1', 'BRD-K83144676-001-07-9', 'BRD-K83144676-001-08-7', 'BRD-K83144676-001-09-5', 'OLMESARTAN MEDOXOMIL IMPURITY A [EP IMPURITY]', 'Z1541758605', 'OLMESARTAN MEDOXOMIL IMPURITY, OLMESARTAN- [USP IMPURITY]', \"1-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid\", \"1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid\", '4-(1-hydroxy-1-methylethyl) -2-propyl-1-{4-[2-(tetrazole -5-yl)phenyl]phenyl}methylimidazole-5-carboxylic acid', '4-(1-hydroxy-1-methylethyl) -2-propyl-1-{4-[2-(tetrazole-5-yl)phenyl]phenyl}methylimidazole-5-carboxylic acid', \"4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid;Olmesa\", \"4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2''-(1H-tetrazol-5-yl)[1,1''-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic acid\", \"4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2''-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid\", '4-(1-Hydroxy-1-methylethyl)-2-propyl-1-{4-[2-(tetrazol-5-yl)phenyl]phenyl}methylimidazole-5-carboxylic acid', '4-(1-hydroxy-1-methylethyl)-2-propyl-1-{4-[2-(tetrazole-5-yl)phenyl]phenyl}methylimidazole-5-carboxylic acid', \"4-(2-hydroxypropan-2-yl)-2-propyl-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-imidazole-5-carboxylic acid\", \"4-(hydroxy-1-methylethyl)-2-propyl-1-{[2''-(1H-tetrazol-5-yl)-1,1''-biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid\"]","Type":"small molecule"},{"Action":"not found","PerturbationName":"QL47","PubChemCID":"71748056","SMILES":"CN1C=C(C=N1)C2=CC3=C4C(=CN=C3C=C2)C=CC(=O)N4C5=CC6=C(CCN6C(=O)C=C)C=C5","Synonyms":"['QL47', '1469988-75-7', 'CHEMBL4077064', 'QL-47', '9-(1-methyl-4-pyrazolyl)-1-[1-(1-oxoprop-2-enyl)-2,3-dihydroindol-6-yl]-2-benzo[h][1,6]naphthyridinone', '9-(1-methylpyrazol-4-yl)-1-(1-prop-2-enoyl-2,3-dihydroindol-6-yl)benzo[h][1,6]naphthyridin-2-one', 'HMSL10077', 'SCHEMBL15334746', 'CHEBI:94815', 'DTXSID201025879', 'HMS3265M21', 'BCP30763', 'UIC98875', 'BDBM50245587', 'AKOS027323841', 'NCGC00346962-01', 'NCGC00346962-02', 'NCGC00346962-03', 'DA-67056', 'HY-80003', 'MS-28101', 'QL 47; QL-47; QL-XII-47', 'F85002', 'BRD-K99252563-001-01-1', 'Q27166580', 'Z2505483026', '1-(1-Acryloylindolin-6-yl)-9-(1-methyl-1H-pyrazol-4-yl)benzo[h][1,6]naphthyridin-2(1H)-one', '9-(1-methylpyrazol-4-yl)-1-[1-(prop-2-enoyl)-2,3-dihydroindol-6-yl]benzo[h]1,6-naphthyridin-2-one']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Kn","PubChemCID":"18218223","SMILES":"C(CCN)CC(C(=O)NC(CC(=O)N)C(=O)O)N","Synonyms":"['CHEBI:174431', '4-amino-2-(2,6-diaminohexanoylamino)-4-oxobutanoic acid', 'KN']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Curcumin","PubChemCID":"969516","SMILES":"COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)OC)O","Synonyms":"['curcumin', '458-37-7', 'Diferuloylmethane', 'Natural yellow 3', 'Kacha haldi', 'Indian saffron', 'Gelbwurz', 'Haldar', 'Curcumin I', 'Souchet', 'Haidr', 'Halad', 'Halud', 'Yellow Ginger', 'Terra Merita', '(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione', \"Safran d'Inde\", 'Yo-Kin', 'C.I. Natural Yellow 3', 'Yellow puccoon', 'Diferaloylmethane', 'Tumeric yellow', 'CI Natural Yellow 3', 'Kurkumin', 'C.I. 75300', 'Zlut prirodni 3', 'Jianghuangsu', 'NanoCurc', 'E 100', '(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione', 'NSC32982', 'NSC 32982', 'CCRIS 3257', 'CHEBI:3962', 'Lipocurc', 'Kurkum', 'HSDB 4334', '1,5-Di(vanillyliden)acetylaceton', 'CI 75300', 'NCI-C61325', '1,5-Divanillyliden-2,4-pentandion', 'EINECS 207-280-5', 'UNII-IT942ZTH98', 'NSC-32982', 'Curcumin e100', 'NSC 687842', 'trans,trans-Curcumin', 'BRN 2306965', 'IT942ZTH98', '1,9-Bis(4-hydroxy-3-methoxyphenyl)-2,7-nonadiene-4,6-dione', 'E 100 (Dye)', 'DTXSID8031077', '1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (E,E)-', 'NSC-687842', '(E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione', 'DTXCID901421', 'INS NO. 100(I)', 'INS-100(I)', '4-08-00-03697 (Beilstein Handbook Reference)', '1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-', 'curouma', 'kachs haldi', '2,7-Nonadiene-4,6-dione, 1,9-bis(4-hydroxy-3-methoxyphenyl)-', \"safra d'inde\", 'CURCUMIN (MART.)', 'CURCUMIN [MART.]', 'CURCUMIN (USP-RS)', 'CURCUMIN [USP-RS]', 'Tumeric', 'Ukon', '1,7-BIS-(4-HYDROXY-3-METHOXYPHENYL)-HEPTA-1,6-DIENE-3,5-DIONE', 'Phytosome, Curcumin', 'Ukon (dye)', 'C Yellow 15', 'Victory 19 Virus Out', 'CURCUMIN (CONSTITUENT OF TURMERIC)', '1,7-BIS(4-HYDROXYMETHOXYPHENYL)-1,6-HEPTADIENE-3,5-DIONE', '207-280-5', 'e-100', 'e100', 'Curcuma', 'Golden seal', 'Curcumine', 'Hydrastis', 'Kurkumin [Czech]', 'Curcumin (synthetic)', 'Zlut prirodni 3 [Czech]', 'Cucurmin', '94875-80-6', 'Tumeric oleoresin', 'MFCD00008365', '1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione', 'Curcurmin', 'MLS000069631', 'CHEMBL140', 'SMR000058237', '1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (1E,6E)-', '(E/Z)-Curcumin', 'NSC687842', 'NCGC00017159-05', '(1E,6E)-1,7-bis(4-hydroxy-3-methoxy-phenyl)hepta-1,6-diene-3,5-dione', '(1E,6E)-1,7-bis[4-hydroxy-3-(methyloxy)phenyl]hepta-1,6-diene-3,5-dione', 'CAS-458-37-7', 'FEMA No. 3085', 'FEMA No. 3086', 'CCRIS 5804', 'SR-01000000149', 'Curcumin (Standard)', 'starbld0017234', 'CURCUMIN [HSDB]', 'CURCUMIN [MI]', 'Opera_ID_1627', 'CURCUMIN [WHO-DD]', 'SCHEMBL8440', 'SCHEMBL8441', 'Curcumin, analytical standard', 'MLS001148449', 'BIDD:ER0479', 'CU-01000001305-2', 'cid_969516', 'GTPL7000', 'SCHEMBL13521974', 'SCHEMBL23884885', 'SCHEMBL23884886', 'SCHEMBL23884892', 'SCHEMBL23884893', 'BDBM29532', 'cid_5281767', 'HY-N0005R', 'cMAP_000052', 'HMS2233K04', 'HMS3649K06', 'BCP04695', 'Tox21_110803', 'Tox21_111505', 'Tox21_201116', 'BBL027711', 'BDBM50067040', 'BDBM50140172', 'CCG-36020', 'CCG-36107', 'STL371943', 'AKOS001305497', 'BCP9000557', 'DB11672', 'FC09321', 'NCGC00017159-04', 'NCGC00017159-06', 'NCGC00017159-07', 'NCGC00017159-09', 'NCGC00017159-10', 'NCGC00017159-11', 'NCGC00017159-12', 'NCGC00023332-03', 'NCGC00023332-04', 'NCGC00023332-05', 'NCGC00258668-01', 'AC-24238', 'AS-72202', 'BP-25396', 'BCP0726000035', 'DB-002681', 'WLN: 1OR BQ E1U1V1V1U1R DQ CO1', 'C2302', 'CS-0149275', 'NS00014804', 'EN300-21494', 'F21478', 'K00009', 'Curcumin, Curcuma longa L. - CAS 458-37-7', 'Curcumin, primary pharmaceutical reference standard', 'Q312266', '1,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-', 'SR-01000000149-2', 'SR-01000000149-5', 'BRD-K07572174-001-02-2', 'BRD-K07572174-001-19-6', 'BRD-K07572174-001-22-0', 'BRD-K07572174-001-38-6', 'BRD-K07572174-001-39-4', 'Z104500108', 'Curcumin, >=94% (curcuminoid content), >=80% (Curcumin)', '1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadien-3,5-dione', '1,7-bis(4-hydroxy-3-methoxyphenyl)1,6-heptadiene-3,5-dione', 'Curcumin, matrix substance for MALDI-MS, >=99.5% (HPLC)', 'Curcumin, United States Pharmacopeia (USP) Reference Standard', '1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,6-diene-3,5-dione', '1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione', '((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione)', '(1E,6E)-1,7-bis(3-methoxy-4-oxidanyl-phenyl)hepta-1,6-diene-3,5-dione', '(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione #', '(1E,6E)-1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,6-diene-3,5-dione', '(1Z,6E)-1,7-Bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,6-diene-3,5-dione', '1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, (E,E)-', '5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,4,6-heptatrien-3-one', '5-Hydroxy-1,7-bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,4,6-trien-3-one', 'Curcumin; 1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione', '(1E,4Z,6E)-5-Hydroxy-1,7-bis-(4-hydroxy-3-methoxy-phenyl)-hepta-1,4,6-trien-3-one']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Dabrafenib","PubChemCID":"44462760","SMILES":"CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F","Synonyms":"['Dabrafenib', '1195765-45-7', 'GSK2118436A', 'UNII-QGP4HA4G1B', 'QGP4HA4G1B', 'GSK-2118436A', 'CHEBI:75045', 'Benzenesulfonamide, N-[3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-', 'DTXSID20152499', 'GSK 2118436A', 'N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide', 'BENZENESULFONAMIDE, N-(3-(5-(2-AMINO-4-PYRIMIDINYL)-2-(1,1-DIMETHYLETHYL)-4-THIAZOLYL)-2-FLUOROPHENYL)-2,6-DIFLUORO-', 'N-(3-(5-(2-AMINOPYRIMIDIN-4-YL)-2-TERT-BUTYL-1,3-THIAZOL-4-YL)-2-FLUOROPHENYL)-2,6-DIFLUOROBENZENESULFONAMIDE', 'N-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide', 'dabrafenibum', 'DTXCID8074990', 'BRAF Inhibitor GSK2118436', 'L01XE23', 'N-(3-(5-(2-aminopyrimidin-4-yl)-2-(1,1-dimethylethyl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide', 'Tafinlar', 'Dabrafenib (GSK2118436)', 'GSK-2118436', 'N-(3-(5-(2-aminopyrimidin-4-yl)-2-tert-butylthiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide', 'GSK 2118436', '1195765-45-7 (free base)', 'N-(3-(5-(2-aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide', 'Dabrafenib (USAN)', 'DABRAFENIB [USAN]', 'Dabrafenib (Free Base)', 'Dabrafenib [USAN:INN]', 'Dabrafenib?', 'N-[3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-benzenesulfonamide; Dabarefenib; GSK 2118436; Tafinlar; GSK 2118436A', 'P06', 'MFCD17215684', 'Dabrafenib (Standard)', 'DABRAFENIB [MI]', 'DABRAFENIB [INN]', 'DABRAFENIB [VANDF]', 'DABRAFENIB [WHO-DD]', 'MLS006011052', 'SCHEMBL806377', 'GTPL6494', 'CHEMBL2028663', 'DABRAFENIB, KB-57246', 'BFSMGDJOXZAERB-UHFFFAOYSA-N', 'HMS3656D12', 'HMS3672G05', 'BCP09341', 'EX-A1320', 'BDBM50428286', 'FD5028', 'HY-14660R', 'NSC764134', 'NSC800083', 'AKOS024463285', 'AKOS032950004', 'CCG-264736', 'CS-0692', 'DB08912', 'FA65034', 'NSC-764134', 'NSC-800083', 'SB13355', 'SDCCGSBI-0654477.P001', 'NCGC00346716-01', 'NCGC00346716-02', 'NCGC00346716-14', 'AC-25889', 'AS-19634', 'DA-62632', 'HY-14660', 'N-[3-[5-(2-Amino-4-pyrimidinyl)-2-(tert-butyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluorobenzenesulfo', 'SMR004702844', '1ST169306', 'NS00040699', 'S2807', 'SW219503-1', 'D10064', 'AB01565833_02', 'Q3011604', 'BRD-K09951645-001-06-8', 'BRD-K09951645-001-08-4', 'BRD-K09951645-001-11-8', 'BRD-K09951645-066-01-2', 'N-(3-(5-(2-Aminopyrimidine-4-yl)-2-tert-butylthiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide;GSK2118436A', 'N-{3-(5-(2-aminopyrimidin-4-yl)-2-(1,1-dimethylethyl)thiazol-4-yl)-2-fluorophenyl}-2,6- difluorobenzenesulfonamide', 'N-{3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Cc","PubChemCID":"5280795","SMILES":"C[C@H](CCCC(C)C)[C@H]1CC[C@@H]\\2[C@@]1(CCC/C2=C\\C=C/3\\C[C@H](CCC3=C)O)C","Synonyms":"['Vitamin D3', 'cholecalciferol', '67-97-0', 'Colecalciferol', 'Calciol', 'Ricketon', 'Oleovitamin D3', 'Deparal', 'Arachitol', 'Delsterol', 'Trivitan', 'Ebivit', 'Vigantol', 'Vigorsan', 'Colecalcipherol', 'Colecalciferolum', 'Cholecalciferolum', 'D3-Vicotrat', 'D3-Vigantol', 'Vi-de-3-hydrosol', 'NEO Dohyfral D3', 'Provitina', 'Rampage', 'Vitinc Dan-Dee-3', 'Cholecalciferol, D3', 'Colecalciferolo', 'Vi-De3', 'Duphafral D3 1000', 'Colecalciferol D3', 'Irradiated 7-dehydrocholesterol', 'CCRIS 6286', 'HSDB 820', 'Videkhol', '7-Dehydrocholesterol, irradiated', 'CHEBI:28940', 'Granuvit D3', 'CC', 'EINECS 200-673-2', 'Colecalciferolum [INN-Latin]', 'EPA Pesticide Chemical Code 202901', 'NSC 375571', 'NSC-375571', 'UNII-1C6V77QF41', 'VIGANTOLETTEN', '1C6V77QF41', '(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol', 'AK R215 COMPONENT COLECALCIFEROL', 'AK-R215 COMPONENT COLECALCIFEROL', '9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol', 'DTXSID6026294', '(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol', '9,10-Secocholesta-5,7,10(19)-trien-3-ol, (3beta,5Z,7E)-', '9,10-Secocholesta-5,7,10(19)-trien-3beta-ol', 'Cholecalciferol [USP:BAN:JAN:ISO]', 'NSC375571', '(3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol', '9,10-Secocholestra-5,7,10(19)-trien-3-ol, (3beta,5Z,7E)-', '9,10-Secocholesta-5,7,10(19)-trien-3-ol', 'Colecalciferolum (INN-Latin)', 'COLECALCIFEROL (MART.)', 'COLECALCIFEROL [MART.]', 'CHOLECALCIFEROL (USP-RS)', 'CHOLECALCIFEROL [USP-RS]', 'CHOLECALCIFEROL (EP MONOGRAPH)', 'Cholecalciferol (USP:BAN:JAN:ISO)', 'CHOLECALCIFEROL [EP MONOGRAPH]', 'CHOLECALCIFEROL (USP MONOGRAPH)', 'CHOLECALCIFEROL [USP MONOGRAPH]', 'DTXCID306294', 'vitaminum d3', 'Osteo-Vit3', 'Novel-D3', 'DECALCITROL', 'VITA-DESIC', 'CHOLECALCIFEROL IMPURITY A (EP IMPURITY)', 'A11CC05', '(1S,3Z)-3-((2E)-2-((1R,3AR,7AS)-7A-METHYL-1-((2R)-6-METHYLHEPTAN-2-YL)-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE)ETHYLIDENE)-4-METHYLIDENE-CYCLOHEXAN-1-OL', '(1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLIDENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL', 'GROWTH SUPPORTPATCH, HAUTUKI', '5,7-CHOLESTADIEN-3-BETAL-OL', 'USEPA/OPP Pesticide Code: 202901', '(5E,7E)-9,10-SECOCHOLESTA-5,7,10(19)-TRIEN-3beta-OL', '200-673-2', 'vitamin d-3', '1406-16-2', '(+)-Vitamin D3', 'Delta-D', 'Quintox', 'FeraCol', 'MFCD00078131', '(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol', 'Colecalciferol [INN]', 'Vitamin d (cholecalciferol)', '9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol', 'Micro-dee', 'Vitamin d3 (as cholecalciferol)', 'Vitamin d assay system suitability', 'VidDe-3-hydrosol', 'Colecalciferol (INN)', 'Vitamin D3 10 microg/mL in Acetonitrile', '(5Z,7E)-(3S)-9,10-seco-5,7,10(19)-cholestatrien-3-ol', '9,10-Secocholesta-5,7,10(19)-trien-3-ol, (3b,5Z,7E)-', '9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3beta-ol', 'Colecalciferolo [DCIT]', '9,10-Secocholesta-5(Z),7(E),10(19)-trien-3(.beta.)-ol', '9,10-Secocholesta-5,7,10(19)-trien-3-ol, (3.beta.,5Z,7E)-', '(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexanol', '(S,Z)-3-(2-((1R,3aS,7aR,E)-7a-methyl-1-((R)-6-methylheptan-2-yl)octahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexan-1-ol', 'Cyclohexanol, 3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1S,3Z)-', 'Vitamin D 3', 'CCRIS 5813', 'Vitamin D3 emulsifiable', 'EINECS 215-797-2', 'UNII-9VU1KI44GP', 'Devaron', 'Vitamin D3 (Cholecalciferol)', '(3.beta.,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol', 'DP-R206', 'Prestwick_63', 'Cholecalciferol D3', 'NCGC00159331-02', 'Cyclohexanol, 3-((2E)-2-((1R,3aS,7aR)-1-((1R)-1,5-dimethylhexyl)octahydro-7a-methyl-4H-inden-4-ylidene)ethylidene)-4-methylene-, (1S,3Z)-', '9,10-secocholesta-5,7,10-trien-3-ol', '()-Vitamin D3', 'Cholecalciferol (D3)', 'Delta-D (TN)', 'Vitamin D3 (Standard)', 'Prestwick3_000429', 'bmse000507', 'UPCMLD-DP152', 'VITAMIN D3 [MI]', 'Vitamin D3;Cholecalciferol', 'VITAMIN D3 [FCC]', 'SCHEMBL3126', '9VU1KI44GP', 'CHEMBL1042', 'BSPBio_000418', 'CHOLECALCIFEROL [ISO]', 'CHOLECALCIFEROL [JAN]', 'Cholecalciferol; 67-97-0', 'Cholecalciferol (JP18/USP)', 'CHOLECALCIFEROL [HSDB]', 'CHOLECALCIFEROL [VANDF]', 'BPBio1_000460', 'MEGxm0_000458', 'COLECALCIFEROL [WHO-DD]', 'COLECALCIFEROL [WHO-IP]', 'UPCMLD-DP152:001', 'ACon1_001997', 'COLECALCIFEROL [EMA EPAR]', 'HMS2096E20', 'Cholecalciferol, >=98% (HPLC)', '(1S)-3-{2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol', '2416217-93-9', 'Cholecalciferol, analytical standard', 'BDBM50030475', 'CHOLECALCIFEROL [ORANGE BOOK]', 'HY-15398R', 'LMST03020001', 's4063', 'Cholecalciferol for system suitability', 'AKOS015950641', 'AC-8884', 'CCG-268466', 'COLECALCIFEROLUM [WHO-IP LATIN]', 'CS-1179', 'DB00169', 'DP-R206 COMPONENT VITAMIN D3', 'FC11742', 'FC45357', 'FV74428', 'SMP1_000068', 'NCGC00091072-01', 'NCGC00159331-04', 'BS-42465', 'HY-15398', 'Cholecalciferol (D3), analytical standard', 'NS00008889', 'C05443', 'D00188', 'FOSAMAX PLUS D COMPONENT CHOLECALCIFEROL', 'Cholecalciferol, meets USP testing specifications', 'Q139347', '(5E,7E)-9,10-Secocholesta-5,7,10-trien-3-ol', 'VITAMIN D ASSAY SYSTEM SUITABILITY [USP-RS]', 'BRD-K62779383-001-05-5', 'Cholecalciferol - 100IU/mg - contains 2.5g/kg active', '3-beta,Z,7E-9,10-Secocholestr-5,7,10(19)-trien-3-ol', '(3beta,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol', 'Cholecalciferol, European Pharmacopoeia (EP) Reference Standard', 'Colecalciferol, British Pharmacopoeia (BP) Reference Standard', 'Cholecalciferol, United States Pharmacopeia (USP) Reference Standard', 'Cholecalciferol for system suitability, European Pharmacopoeia (EP) Reference Standard', '(1S,3Z)-3-[(2E)-2-[7a-Methyl-1-(6-methylheptan-2-yl)-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol', 'Cholecalciferol (Vitamin D3), Pharmaceutical Secondary Standard; Certified Reference Material']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Tbb","PubChemCID":"1694","SMILES":"C1(=C(C2=NNN=C2C(=C1Br)Br)Br)Br","Synonyms":"['TETRABROMO-2-BENZOTRIAZOLE', '4,5,6,7-tetrabromo-2H-1,2,3-benzotriazole', '17374-26-4', '4,5,6,7-tetrabromobenzotriazole', 'TBB', '4,5,6,7-Tetrabromo-1H-benzotriazole', 'TBBt', '4,5,6,7-tetrabromo-2H-benzotriazole', '4,5,6,7-Tetrabromo-1H-benzo[d][1,2,3]triazole', '1H-Benzotriazole, 4,5,6,7-tetrabromo-', 'Casein Kinase II Inhibitor I', 'NSC 231634', 'CHEMBL177820', 'MFCD06411399', 'NSC231634', '4,5,6,7-Tetrabromo-2-azabenzimidazole', 'TBB;TBBT', '1p5e', 'TBB?', 'SCHEMBL263343', 'GTPL9372', 'STO170', 'SCHEMBL16463781', 'BDBM11323', 'DTXSID20274322', 'BDBM420315', 'HMS2043P01', 'HMS3229D01', 'HMS3262L12', 'HMS3268H06', 'HMS3413A16', 'HMS3677A16', 'BCP04100', 'TBB (NSC 231634)', 'TBB, >=98% (HPLC), solid', 'Tox21_500935', 'HSCI1_000172', 's5265', 'AKOS015951304', 'AKOS026750603', 'CCG-222239', 'CS-1079', 'DB04462', 'LP00935', 'NSC-231634', 'SDCCGSBI-0207141.P002', 'NCGC00092352-01', 'NCGC00092352-02', 'NCGC00092352-03', 'NCGC00092352-04', 'NCGC00261620-01', '1H-Benzoriazole, 4,5,6,7-tetrahydro-', 'AC-33147', 'AS-16678', 'HY-14394', 'BCP0726000105', 'DB-099581', 'NS00069466', 'T2920', '4,5,6,7-tetrabromo-1h-1,2,3-benzotriazole', 'K00040', '1H-1,2,3-benzotriazole, 4,5,6,7-tetrabromo-', 'A907699', 'Casein Kinase II Inhibitor I - CAS 17374-26-4', 'BRD-K97118047-001-01-2', 'BRD-K97118047-001-02-0', 'BRD-K97118047-001-03-8', 'Q27095242']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Sch 900776","PubChemCID":"46239015","SMILES":"CN1C=C(C=N1)C2=C3N=C(C(=C(N3N=C2)N)Br)[C@@H]4CCCNC4","Synonyms":"['SCH900776', 'SCH-900776', 'UNII-K2ZSF0992C', 'MK-8776', 'DTXSID00237551', 'MK 8776', 'CHK1 Inhibitor MK-8776', 'DTXCID50160042', '6-bromo-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo(5,1-b)pyrimidin-7-amine', '6-bromo-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[5,1-b]pyrimidin-7-amine', '891494-63-6', 'SCH 900776', 'MK-8776 (SCH 900776)', '(R)-6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(piperidin-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine', '6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(3R)-3-piperidinylpyrazolo[1,5-a]pyrimidin-7-amine', 'K2ZSF0992C', 'CHEMBL2386889', '(R)-6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(piperidin-3-yl)pyrazolo(1,5-a)pyrimidin-7-amine', '6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-((3R)-piperidin-3-yl)pyrazolo(1,5-a)pyrimidin-7-amine', 'Pyrazolo(1,5-a)pyrimidin-7-amine, 6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(3R)-3-piperidinyl-', '6-BROMO-3-(1-METHYLPYRAZOL-4-YL)-5-[(3R)-PIPERIDIN-3-YL]PYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE', 'MFCD20922873', 'MK-8776 dihydrochloride', 'SCH900776 dihydrochloride', 'SCHEMBL2408669', 'EX-A141', 'GLXC-04978', 'BDBM50434372', 'NSC800880', 's2735', 'AKOS024464752', 'CCG-268365', 'CS-1117', 'DB11899', 'NSC-800880', 'NCGC00346653-02', 'NCGC00346653-07', 'NCGC00386188-01', 'NCGC00386188-03', 'AC-32854', 'AS-16307', 'DA-75594', 'HY-15532', 'MK-8776(SCH 900776)', 'NS00072861', 'SW219954-1', 'MK-8776 (SCH 900776)?', 'BRD-K75009076-001-01-3', 'BRD-K75009076-001-02-1', '(r)-(-)-6-bromo-3-(1-methyl-1h-pyrazol-4-yl)-5-piperidin-3-yl-pyrazolo[1,5-a]pyrimidin-7-ylamine', '(R)-6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(piperidin-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine dihydrochloride', '6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(3R)-3-piperidinylpyrazolo[1,5-a]pyrimidin-7-amineMK-8776', '6-Bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3R)-3-piperidinyl]pyrazolo[1,5-a]pyrimidin-7-amine']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Ku0063794","PubChemCID":"16736978","SMILES":"C[C@@H]1CN(C[C@@H](O1)C)C2=NC3=C(C=CC(=N3)C4=CC(=C(C=C4)OC)CO)C(=N2)N5CCOCC5","Synonyms":"['Ku-0063794', '938440-64-3', 'KU0063794', 'KU-63794', 'KU 0063794', '81HJG228AB', 'CHEBI:85572', 'Ku63794', 'Ku 63794', 'Benzenemethanol, 5-(2-((2R,6S)-2,6-dimethyl-4-morpholinyl)-4-(4-morpholinyl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxy-', 'DTXSID50239782', '(5-{2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-(morpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl}-2-methoxyphenyl)methanol', 'rel-5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol', '[5-[2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-morpholin-4-ylpyrido[5,6-e]pyrimidin-7-yl]-2-methoxyphenyl]methanol', '(5-(2-((2R,6S)-2,6-dimethylmorpholin-4-yl)-4-(morpholin-4-yl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxyphenyl)methanol', '(5-(2-((2R,6S)-2,6-dimethylmorpholin-4-yl)-4-morpholin-4-ylpyrido(5,6-e)pyrimidin-7-yl)-2-methoxyphenyl)methanol', 'rel-5-(2-((2R,6S)-2,6-Dimethyl-4-morpholinyl)-4-(4-morpholinyl)pyrido(2,3-d)pyrimidin-7-yl)-2-methoxybenzenemethanol', 'DTXCID00162273', '(5-(2-((2R,6S)-2,6-dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol', 'CHEMBL1078983', '(5-(2-(cis-2,6-Dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol', 'UNII-81HJG228AB', '[5-[2-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-4-morpholin-4-ylpyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol', 'MFCD22666594', 'MLS006011007', 'SCHEMBL290211', 'GTPL9360', 'EX-A045', 'BCP01931', 'BDBM50310989', 'HB2250', 's1226', 'AKOS005145564', 'BCP9000821', 'CCG-264870', 'CS-0065', 'EX-5106', 'FK65052', 'SDCCGSBI-0654360.P001', 'NCGC00250396-01', '5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyben', 'AC-31515', 'AS-16210', 'HY-50710', 'SMR004702805', 'SW220188-1', 'F17370', 'KU 0063794, >=98% (HPLC)', 'BRD-K67566344-001-01-8', 'BRD-K67566344-001-07-5', 'BRD-K67566344-001-08-3', 'Q27158643', 'mTOR Inhibitor IV, Ku-63794 - CAS 938440-64-3', '{5-[2-((2S,6R)-2,6-Dimethyl-morpholin-4-yl)-4-morpholin-4-yl-pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-phenyl}-methanol', 'rel-5-[2-[(2R,6S)-2,6-dimethyl-4-mo rpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin -7-yl]-2-methoxybenzenemethanol']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"JNK","PubChemCID":"10364826","SMILES":"COC1CCC(CC1)C(=O)NC2=NC=CC(=C2)C3=CC(=NC=C3)NC4=CC=C(C=C4)F","Synonyms":"[\"N-{2'-[(4-Fluorophenyl)amino]-4,4'-Bipyridin-2-Yl}-4-Methoxycyclohexanecarboxamide\", 'CHEBI:43460', '(1r,4r)-N-(4-{2-[(4-fluorophenyl)amino]pyridin-4-yl}pyridin-2-yl)-4-methoxycyclohexane-1-carboxamide', \"N-(2'-((4-fluorophenyl)amino)-4,4'-bipyridin-2-yl)-4-methoxycyclohexanecarboxamide\", '(1r,4r)-N-(4-(2-((4-fluorophenyl)amino)pyridin-4-yl)pyridin-2-yl)-4-methoxycyclohexane-1-carboxamide', 'CHEMBL202676', 'CHEMBL203631', 'N-[4-[2-(4-fluoroanilino)pyridin-4-yl]pyridin-2-yl]-4-methoxycyclohexane-1-carboxamide', '2exc', 'JNK', 'SCHEMBL1518805', 'SCHEMBL17223597', 'SCHEMBL21068073', 'BDBM50178839', 'BDBM50178847', 'DB08025', 'PD005241', 'PD037526', 'NS00073278', 'Q27097256', 'cis-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyridin-2-yl)-4-methoxycyclohexanecarboxamide', \"trans-N-{2'-[(4-fluorophenyl)amino]-4,4'-bipyridin-2-yl}-4-methoxycyclohexanecarboxamide\", \"4-METHOXY-CYCLOHEXANECARBOXYLIC ACID [2'-(4-FLUORO-PHENYLAMINO)-[4,4'] BIPYRIDINYL-2-YL]-AMIDE\", \"N-{2''-[(4-FLUOROPHENYL)AMINO]-4,4''-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE\", 'trans-N-(4-(2-(4-fluorophenylamino)pyridin-4-yl)pyridin-2-yl)-4-methoxycyclohexanecarboxamide']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Alpelisib","PubChemCID":"56649450","SMILES":"CC1=C(SC(=N1)NC(=O)N2CCC[C@H]2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F","Synonyms":"['alpelisib', '1217486-61-7', 'Vijoice', 'BYL 719', 'UNII-08W5N2C97Q', '08W5N2C97Q', '1,2-PYRROLIDINEDICARBOXAMIDE, N1-[4-METHYL-5-[2-(2,2,2-TRIFLUORO-1,1-DIMETHYLETHYL)-4-PYRIDINYL]-2-THIAZOLYL]-, (2S)-', '1,2-Pyrrolidinedicarboxamide, N1-(4-methyl-5-(2-(2,2,2-trifluoro-1,1-dimethylethyl)-4-pyridinyl)-2-thiazolyl)-, (2S)-', 'alpelisibum', '(2S)-N1-(4-METHYL-5-(1-(1,1,1-TRIFLUORO-2-METHYLPROPAN-2-YL)PYRIDIN-4-YL)-1,3-THIAZOL-2-YL)PYRROLIDINE-1,2-DICARBOXAMIDE', '(2S)-N1-(4-Methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)-1,3-thiazol-2-yl)pyrrolidine-1,2-dicarboxamide', '(2S)-N1-{4-Methyl-5-[1-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide', '(2S)-N1-{4-METHYL-5-[2-(1,1,1-TRIFLUORO-2-METHYLPROPAN-2-YL)PYRIDIN-4-YL]-1,3-THIAZOL-2-YL}PYRROLIDINE-1,2-DICARBOXAMIDE', 'L01XX65', 'Phosphoinositide 3-kinase Inhibitor BYL719', 'BYL-719', 'BYL719', 'Piqray', 'NVP-BYL719', 'Alpelisib (BYL719)', '(S)-N1-(4-Methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-yl)pyrrolidine-1,2-dicarboxamide', 'Alpelisib [USAN:INN]', '(2S)-1-N-[4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide', 'CHEMBL2396661', '(S)-Pyrrolidine-1,2-dicarboxylic acid 2-amide 1-(4-methyl-5-(2-(2,2,2-trifluoro-1,1-dimethylethyl)-pyridin-4-yl)thiazol-2-yl)amide', 'Alpelisib [INN]', '(2s)-N~1~-{4-Methyl-5-[2-(1,1,1-Trifluoro-2-Methylpropan-2-Yl)pyridin-4-Yl]-1,3-Thiazol-2-Yl}pyrrolidine-1,2-Dicarboxamide', '(S)-N1-(4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-yl)pyrrolidine-1,2-dicarboxamide.', 'C19H22F3N5O2S', '4jps', '(2S)-1-N-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide', '1LT', 'Alpelisib [USAN]', 'Vijoice (TN)', 'MFCD22417085', 'Piqray (TN)', 'ALPELISIB [JAN]', 'ALPELISIB [MI]', 'ALPELISIB [WHO-DD]', 'Alpelisib (JAN/USAN/INN)', 'GTPL7955', 'SCHEMBL1911869', 'ALPELISIB [ORANGE BOOK]', 'CHEBI:93752', 'DTXSID70153355', 'EX-A405', 'STUWGJZDJHPWGZ-LBPRGKRZSA-N', 'BYL 719; BYL719', 'BDBM50436459', 'NSC765974', 'NSC800065', 's2814', 'AKOS022186315', 'CCG-269139', 'CS-0663', 'DB12015', 'FP71607', 'NSC-765974', 'NSC-800065', 'SDCCGSBI-0654479.P001', 'NCGC00346717-03', 'NCGC00346717-06', 'NCGC00346717-12', '(2S)-N1-[4-Methyl-5-[2-(2,2,2-trifluoro-1,1-dimethylethyl)-4-pyridinyl]-2-thiazolyl]-1,2-pyrrolidine', 'AC-37083', 'AS-16349', 'HY-15244', 'NS00072895', 'SW220128-1', 'cas:1217486-61-7;BYL-719', 'D11011', 'EN300-23810842', 'BRD-K54997624-001-06-0', 'Q27074391', '(S)-Pyrrolidine-1,2-dicarboxylic acid 2-amide 1-[4-methyl-5-[2-(2,2,2-trifluoro-1,1-dimethylethyl)-pyridin-4-yl]thiazol-2-yl]amide;A  lpelisib']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"CAL101","PubChemCID":"11625818","SMILES":"CC[C@@H](C1=NC2=C(C(=CC=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5","Synonyms":"['Idelalisib', '870281-82-6', 'Zydelig', 'GS-1101', 'CAL101', 'UNII-YG57I8T5M0', 'GS 1101', 'YG57I8T5M0', 'CHEBI:82701', '5-Fluoro-3-phenyl-2-((S)-1-(9H-purin-6-ylamino)-propyl)-3H-quinazolin-4-one', 'HSDB 8408', 'CAL-101/CAL101', '4(3H)-QUINAZOLINONE, 5-FLUORO-3-PHENYL-2-((1S)-1-(1H-PURIN-6-YLAMINO)PROPYL)-', '4(3H)-QUINAZOLINONE, 5-FLUORO-3-PHENYL-2-((1S)-1-(9H-PURIN-6-YLAMINO)PROPYL)-', '5-fluoro-3-phenyl-2-[(1S)-1-(3H-purin-6-ylamino)propyl]quinazolin-4(3H)-one', 'idelalisibum', '5-fluoro-3-phenyl-2-((1S)-1-(3H-purin-6-ylamino)propyl)quinazolin-4(3H)-one', 'L01XX47', 'Phosphoinositide-3 Kinase Delta Inhibitor CAL-101', '5-Fluoro-3-phenyl-2-((1S)-1-((7H-purin-6-yl)amino)propyl)quinazolin-4(3H)-one', 'CAL-101', 'CAL 101', '(S)-2-(1-((9H-Purin-6-yl)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one', 'Idelalisib (CAL-101)', 'CAL-101 (Idelalisib, GS-1101)', '(S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one', 'CHEMBL2216870', '4(3H)-Quinazolinone,5-fluoro-3-phenyl-2-[(1S)-1-(1H-purin-6-ylamino)propyl]-', '5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one', 'Idelalisib; CAL-101', 'GS-1101; Idelalisib; CAL-101', '5-Fluoro-3-Phenyl-2-[(1s)-1-(7h-Purin-6-Ylamino)propyl]quinazolin-4(3h)-One', '1453810-72-4', 'Idelalisib [INN]', 'Idelalisib [USAN:INN]', 'Idealisib', 'C22H18FN7O', 'Zydelig (TN)', 'MFCD19443647', 'IDELALISIB [MI]', 'IDELALISIB [JAN]', 'IDELALISIB [USAN]', 'IDELALISIB [VANDF]', 'IDELALISIB [WHO-DD]', 'MLS006010985', 'Idelalisib (JAN/USAN/INN)', 'SCHEMBL356400', 'GTPL6741', 'IDELALISIB [ORANGE BOOK]', 'SCHEMBL16782604', 'EX-A330', 'GS-11CAL-101', 'BCPP000307', 'DTXSID701007266', 'BCP02532', 'EX-A1242', 'BDBM50403068', 'NSC759224', 'NSC762828', 'NSC800771', 's2226', 'AKOS022186334', 'AKOS040744041', 'Idelalisib (CAL-101,GS-1101)', 'BCP9000471', 'CCG-264949', 'CS-0256', 'DB09054', 'FI29231', 'NSC-759224', 'NSC-762828', 'NSC-800771', 'SDCCGSBI-0654408.P001', '5-FLUORO-3-PHENYL-2-[(1S)-1-(9H-PURIN-6-YLAMINO)PROPYL]-4(3H)-QUINAZOLINONE', 'CAL-101 (GS-1101)', 'NCGC00262603-01', 'NCGC00262603-02', 'NCGC00262603-04', 'AC-28394', 'AC-36641', 'HY-13026', 'IC489666', 'SMR004702787', 'DB-333007', 'NS00071041', 'SW219823-1', 'A-1138', 'D10560', 'EN300-7412931', 'Q5908266', 'BRD-K60866521-001-01-4', 'BRD-K60866521-001-07-1', '(S)-5-fluoro-3-phenyl-2-[1-(9H-purin-6-ylamino)-propyl]-3H-quinazolin-4-one', '5-fluoro-3-phenyl-2-[(1S)-1-[(9H-purin-6-yl)amino]propyl]-3,4-dihydroquinazolin-4-one', '(S)-2-(1-(1-(9H-Purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;CAL-101;GS-1101', '40L']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Gsk1210151a","PubChemCID":"52912189","SMILES":"CC1=C(C(=NO1)C)C2=C(C=C3C(=C2)N=CC4=C3N(C(=O)N4)[C@H](C)C5=CC=CC=N5)OC","Synonyms":"['7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one', '7-(3,5-Dimethyl-4-isoxazolyl)-8-(methyloxy)-1-[(1R)-1-(2-pyridinyl)ethyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one', '7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-((1R)-1-(2-pyridinyl)ethyl)-2H-imidazo(4,5-c)quinolin-2-one', '7-(3,5-Dimethyl-4-isoxazolyl)-8-(methyloxy)-1-((1R)-1-(2-pyridinyl)ethyl)-1,3-dihydro-2H-imidazo(4,5-c)quinolin-2-one', '802-803-9', '1300031-49-5', 'I-BET151', 'GSK1210151A', 'I-BET151 (GSK1210151A)', '7-(3,5-Dimethylisoxazol-4-yl)-8-methoxy-1-((R)-1-(pyridin-2-yl)ethyl)-1H-imidazo[4,5-c]quinolin-2(3H)-one', 'I-BET 151', 'GSK1210151A (I-BET151)', '2H-Imidazo[4,5-c]quinolin-2-one, 7-(3,5-dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-', 'CHEMBL2017291', 'I-BET-151', '7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(1R)-1-pyridin-2-ylethyl]-3H-imidazo[4,5-c]quinolin-2-one', '(R)-7-(3,5-dimethylisoxazol-4-yl)-8-methoxy-1-(1-(pyridin-2-yl)ethyl)-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one', '7-(3,5-Dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(1R)-1-(pyridin-2-yl)ethyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one', '7-(3,5-Dimethyl-1,2-Oxazol-4-Yl)-8-Methoxy-1-[(1r)-1-(Pyridin-2-Yl)ethyl]-1h,2h,3h-Imidazo[4,5-C]quinolin-2-One', '3zyu', '4alg', 'VUVUVNZRUGEAHB-CYBMUJFWSA-N', '1GH', '7-(3,5-dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(1R)-1-(pyridin-2-yl)ethyl]-3H-imidazo[4,5-c]quinolin-2-one', 'MFCD22124472', 'MLS006011182', 'GTPL7518', 'SCHEMBL1906755', 'CHEBI:95083', 'I-BET151?', 'DTXSID10680599', 'BCP03612', 'EX-A1561', 'BDBM50380682', 'NSC767599', 's2780', 'AKOS016004407', 'BCP9000734', 'CS-0930', 'FD43075', 'NSC-767599', 'GSK1210151A/I-BET 151', 'NCGC00344588-01', 'NCGC00344588-04', 'NCGC00344588-08', 'NCGC00344588-15', 'NCGC00344588-17', '7-(3,5-Dimethyl-4-isoxazolyl)-1,3-dihydro-8-methoxy-1-[(1R)-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]q', 'AC-27406', 'HY-13235', 'SMR004702951', 'BCP0726000180', 'SW219264-1', 'C72196', 'BRD-K36363294-001-04-2', 'Q27078015', '7-(dimethyl-1,2-oxazol-4-yl)-8-methoxy-1-[(1R)-1-(pyridin-2-yl)ethyl]-1H,2H,3H-imidazo[4,5-c]quinolin-2-one']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"GSK690693","PubChemCID":"16725726","SMILES":"CCN1C2=C(C(=NC=C2OC[C@H]3CCCNC3)C#CC(C)(C)O)N=C1C4=NON=C4N","Synonyms":"['GSK690693', 'GSK-690693', 'GSK 690693', 'UNII-GWH480321B', 'CHEBI:90677', 'compound 3g [PMID 18800763]', 'DTXSID60239551', '4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-piperidin-3-ylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol', 'compound 3g (PMID 18800763)', '(-)-4-(2-(4-AMINO-1,2,5-OXADIAZOL-3-YL)-1-ETHYL-7-((3S)-3-PIPERIDINYLMETHOXY)-1H-IMIDAZO(4,5-C)PYRIDIN-4-YL)-2-METHYL-3-BUTYN-2-OL', '3-BUTYN-2-OL, 4-(2-(4-AMINO-1,2,5-OXADIAZOL-3-YL)-1-ETHYL-7-((3S)-3-PIPERIDINYLMETHOXY)-1H-IMIDAZO(4,5-C)PYRIDIN-4-YL)-2-METHYL-', '4-(2-(4-AMINO-1,2,5-OXADIAZOL-3-YL)-1-ETHYL-7-((3S)-3-PIPERIDINYLMETHOXY)-1H-IMIDAZO(4,5-C)PYRIDIN-4-YL)-2-METHYL-3-BUTYN-2-OL, (-)-', '4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-piperidin-3-yl]methoxy}-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol', '4-{2-(4-Amino-1,2,5-Oxadiazol-3-Yl)-1-Ethyl-7-[(3s)-Piperidin-3-Ylmethoxy]-1h-Imidazo[4,5-C]pyridin-4-Yl}-2-Methylbut-3-Yn-2-Ol', '4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(((3S)-piperidin-3-yl)methoxy)-1H-imidazo(4,5-c)pyridin-4-yl)-2-methylbut-3-yn-2-ol', '4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-((3S)-piperidin-3-ylmethoxy)-1H-imidazo(4,5-c)pyridin-4-yl)-2-methylbut-3-yn-2-ol', 'DTXCID10162042', 'PAN-AKT KINASE INHIBITOR GSK690693', '937174-76-0', '(S)-4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-(piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol', 'GWH480321B', '4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol', '4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[[(3S)-piperidin-3-yl]methoxy]imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol', '4-{2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-piperidin-3-ylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl}-2-methylbut-3 -yn-2-ol', 'G93', '-yn-2-ol', 'SCHEMBL310452', 'CHEMBL494089', 'GTPL5196', 'pan-Akt inhibitor GS690693', 'BDBM25013', 'EX-A031', 'GLXC-05503', '4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol', 'BCP01721', 'NSC766991', 'NSC800766', 's1113', 'AKOS015904356', 'AT18727', 'BCP9000745', 'CCG-264825', 'DB12745', 'NSC-766991', 'NSC-800766', 'SDCCGSBI-0654451.P001', 'NCGC00263181-01', '4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-piperidin-3-ylmethoxy]imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol', 'AC-23166', 'AS-16204', 'BG174974', 'HY-10249', 'GSK690693,GSK-690693', 'NS00072069', 'SW218127-2', 'GSK690693, >=98% (HPLC)', 'BRD-K25325018-001-02-3', 'BRD-K25325018-001-05-6', 'Q27077916', '4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-((S)-piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol', '4-{2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-piperidin-3-ylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl}-2-methylbut-3']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Losmapimod","PubChemCID":"11552706","SMILES":"CC1=C(C=C(C=C1F)C(=O)NC2CC2)C3=NC=C(C=C3)C(=O)NCC(C)(C)C","Synonyms":"['Losmapimod', '585543-15-3', 'GW856553', 'GW856553X', 'GSKAHAB', 'GW-856553', 'Losmapimod [USAN:INN]', 'F2DQF16BXE', '6-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide', 'FTX1821', '6-(5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl)-N-neopentylnicotinamide', 'FTX-1821', 'LOSMAPIMOD [INN]', 'LOSMAPIMOD [USAN]', 'GW 856553X', 'GW-856553X', 'LOSMAPIMOD [WHO-DD]', 'SB 856553', 'DTXSID30974109', 'GS856553', '3-PYRIDINECARBOXAMIDE, 6-(5-((CYCLOPROPYLAMINO)CARBONYL)-3-FLUORO-2-METHYLPHENYL)-N-(2,2-DIMETHYLPROPYL)-', '6-(5-((CYCLOPROPYLAMINO)CARBONYL)-3-FLUORO-2-METHYLPHENYL)-N-(2,2-DIMETHYLPROPYL)-3-PYRIDINECARBOXAMIDE', 'losmapimodum', '6-[5-(Cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-neopentylnicotinamide', '3-pyridinecarboxamide, 6-[5-[(cyclopropylamino)carbonyl]-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)-', '6-(5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl)-N-(2,2-dimethylpropyl)pyridine-3-carboxamide', 'DTXCID701401545', '629-887-8', 'GSK-AHAB', 'Losmapimod (GW856553X)', 'MFCD16619322', 'GSK-AHAB;GW856553X;SB856553', '6-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide.', 'UNII-F2DQF16BXE', 'Losmapimod?', 'C22H26FN3O2', 'Losmapimod (USAN/INN)', 'Losmapimod,gw-856553', 'GTPL7835', 'SCHEMBL1070401', 'CHEMBL1088752', 'EX-A486', 'CHEBI:131167', 'KKYABQBFGDZVNQ-UHFFFAOYSA-N', 'HMS3653G19', 'HMS3673K13', 'losmapimod  pound>>GW-856553', 'BCP09909', 'BDBM50418610', 'NSC785336', 'NSC800785', 's7215', 'AKOS015994587', 'CCG-268442', 'CS-3235', 'DB12270', 'GE-0056', 'NSC-785336', 'NSC-800785', 'SB16761', 'NCGC00386332-03', 'NCGC00481552-01', 'AC-35781', 'DA-33431', 'HY-10402', 'SY358295', 'NS00072158', 'SW219307-1', 'D09639', 'Q6683687', 'BRD-K56195681-001-01-0', '6-(5-cyclopropylcarbamoyl-3-fluoro-2-methyl-phenyl)-N-(2,2-dimethylpropyl)-nicotinamide', '6-[5-(Cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)nicotinamide']","Type":"small molecule"},{"Action":"Not found","PerturbationName":"Ginkgetin","PubChemCID":"5271805","SMILES":"COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)OC)O)C4=C(C=C(C5=C4OC(=CC5=O)C6=CC=C(C=C6)O)O)O","Synonyms":"['Ginkgetin', '481-46-9', \"7,4'-Dimethylamentoflavone\", \"Amentoflavone 7,4'-dimethyl ether\", 'CHEBI:5353', 'HY5EZW8269', '5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)chromen-4-one', 'DTXSID70197416', '4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl)-2-(4-hydroxyphenyl)-', '4H-1-Benzopyran-4-one, 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)-', '5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)-4H-chromen-4-one', \"3''',8-Biflavone, 4',5,5'',7-tetrahydroxy-4''',7''-dimethoxy-\", \"4''',5,5'',7''-tetrahydroxy-4',7-dimethoxy-(3'->8'')-biflavone\", '5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl)-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one', '5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one', '5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl)-2-(4-hydroxyphenyl)-4H-chromen-4-one', '5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxochromen-2-yl)-2-methoxyphenyl)-2-(4-hydroxyphenyl)chromen-4-one', 'DTXCID80119907', 'aifcfbuslaeibr-uhfffaoysa-n', 'Ginkgetin (Standard)', 'Spectrum_001932', 'Spectrum2_000054', 'Spectrum3_001727', 'Spectrum4_001610', 'Spectrum5_000339', 'UNII-HY5EZW8269', 'BSPBio_003374', 'KBioGR_001959', 'KBioSS_002476', 'SCHEMBL888410', 'SPBio_000207', 'jm5b01461, Compound 89', 'HY-N0889R', 'KBio2_002469', 'KBio2_005037', 'KBio2_007605', 'KBio3_002594', 'BDBM429271', 'HY-N0889', 'LMPK12040003', 'MFCD09970948', 'AKOS015896770', 'CS-3727', \"Ginkgetin 7''-O-beta-D-glucopyranoside\", '5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-chromen-2-yl)-2-methoxy-phenyl]-2-(4-hydroxyphenyl)chromen-4-one', 'AC-35029', 'DA-53556', 'MS-30254', 'BRD-K92123432-237-02-8', 'Q27089352']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"H89","PubChemCID":"449241","SMILES":"C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCNC/C=C/C3=CC=C(C=C3)Br","Synonyms":"['Protein kinase inhibitor H89', 'DTXSID801022528', 'DTXCID601507213', 'h-89', '127243-85-0', 'H 89', 'N-(2-(4-Bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide', 'N-[2-[[(E)-3-(4-bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5-sulfonamide', 'H-89 DIHYDROCHLORIDE', 'Protein kinase inhibitor H-89', 'N-[2-(P-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE', 'H89', '5-Isoquinolinesulfonamide, N-[2-[[3-(4-bromophenyl)-2-propen-1-yl]amino]ethyl]-', 'CHEMBL104264', 'N-(2-{[(2E)-3-(4-bromophenyl)prop-2-en-1-yl]amino}ethyl)isoquinoline-5-sulfonamide', 'M876330O56', 'N-(2-((3-(4-Bromophenyl)allyl)amino)ethyl)isoquinoline-5-sulfonamide', '5-Isoquinolinesulfonamide, N-(2-((3-(4-bromophenyl)-2-propenyl)amino)ethyl)-', 'N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE', 'N-(2-{[3-(4-bromophenyl)prop-2-en-1-yl]amino}ethyl)isoquinoline-5-sulfonamide', 'CHEBI:47495', 'N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide', '1ydt', '5-ISOQUINOLINESULFONAMIDE, N-(2-((3-(4-BROMOPHENYL)-2-PROPEN-1-YL)AMINO)ETHYL)-', 'UNII-M876330O56', 'H-89 free base?', 'H-89 (E-isomer)', 'BiomolKI_000035', 'BiomolKI2_000043', 'H-89 (hydrochloride salt)', 'N-(2-((3-(4-Bromophenyl)-2-propenyl)amino)ehtyl)-5-isoquinolinesulfonamide dihydrochloride', 'Lopac0_000140', 'BSPBio_001107', 'SCHEMBL123495', 'BMK1-D11', 'GTPL5983', 'BDBM15211', 'BRD7647', 'CHEBI:191396', 'ZKZXNDJNWUTGDK-NSCUHMNNSA-N', 'BCPP000214', 'HMS1362G09', 'HMS1792G09', 'HMS1990G09', 'HMS3403G09', 'BCP02706', 'BRD-7647', 'EX-A2432', 'EI-196', 'NSC755766', 'NSC782017', '(E)-N-(2-((3-(4-bromophenyl)allyl)amino)ethyl)isoquinoline-5-sulfonamide', 'AKOS025394289', 'AKOS037647444', 'BCP9000757', 'CCG-100639', 'CS-3386', 'DB07995', 'NSC-755766', 'NSC-782017', 'SDCCGSBI-0050128.P005', 'IDI1_002139', 'N-[2-[[3-(4-Bromophenyl)-2-propen-1-yl]amino]ethyl]-5-isoquinolinesulfonamide', 'NCGC00162073-01', 'NCGC00162073-02', 'NCGC00162073-03', 'NCGC00162073-04', 'NCGC00162073-07', 'NCGC00162073-13', 'NCGC00162073-14', 'AC-27757', 'AS-73687', 'HY-15979', 'NS00068838', 'H-89, Dihydrochloride - CAS 127243-85-0', 'Q5627831', 'BRD-K27737647-001-04-2', 'BRD-K27737647-300-01-4', 'BRD-K27737647-300-03-0', 'BRD-K27737647-300-04-8', 'BRD-K27737647-300-08-9', 'N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide', '(E)-N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide', 'N-[2-(p-Bromocinnamylamino)ethyl]-5-Isoquinoline Sulfonamide, 98%', 'N-[2-[[(E)-3-(4-bromophenyl)allyl]amino]ethyl]isoquinoline-5-sulfonamide', '1000995-75-4']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"PIK294","PubChemCID":"24905149","SMILES":"CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C5=NC=NC(=C5C(=N4)C6=CC(=CC=C6)O)N","Synonyms":"['PIK-294', '110-148-9', '900185-02-6', '2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one', 'PIK294', '2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one', '2-[[4-amino-3-(3-hydroxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one', '2-{[4-amino-3-(3-hydroxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl}-5-methyl-3-(2-methylphenyl)quinazolin-4-one', 'PIK 294', 'MLS006010993', 'SCHEMBL1952680', 'CHEMBL1241767', 'BDBM36411', 'DTXSID20648004', 'GLXC-05522', 'HMS3244E13', 'HMS3244E14', 'HMS3244F13', 'HMS3655P12', 'BCP01970', 'EX-A2568', 'PIK-294?', 's2227', 'AKOS026750411', 'CCG-269607', 'CS-3528', 'SDCCGSBI-0654410.P001', 'CID24905149', 'NCGC00346614-01', 'NCGC00346614-02', 'NCGC00346614-07', '4(3H)-Quinazolinone, 2-[[4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-methyl-3-(2-methylphenyl)-', 'AC-32796', 'AS-16244', 'HY-10303', 'SMR004702793', 'DB-339677', 'PIK-294, >=98% (HPLC)', 'SW220212-1', 'BRD-K50631926-001-02-3', '2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one, PIK294', '2-{[4-Amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl}-5-methyl-3-(2-methylphenyl)quinazolin-4(3H)-one']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Seliciclib","PubChemCID":"160355","SMILES":"CC[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3","Synonyms":"['roscovitine', 'Seliciclib', 'R-Roscovitine', 'Roscovitin', 'CYC 202', 'Seliciclib [INN]', '2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine', 'NSC-701554', 'AL-39256', 'NSC 701554', 'CHEBI:45307', '(2R)-2-[[6-(benzylamino)-9-propan-2-ylpurin-2-yl]amino]butan-1-ol', 'SELICICLIB [MI]', 'SELICICLIB [WHO-DD]', '(2R)-2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol', 'DTXSID20171928', '(2R)-2-{[6-(benzylamino)-9-(1-methylethyl)-9H-purin-2-yl]amino}butan-1-ol', '(2R)-2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-1-butanol', '(R)-2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-1-butanol', '1-Butanol, 2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-, (2R)-', '1-Butanol, 2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-, (R)-', 'seliciclibum', '(2R)-2-((6-(benzylamino)-9-propan-2-ylpurin-2-yl)amino)butan-1-ol', '(2R)-2-((6-(benzylamino)-9-(1-methylethyl)-9H-purin-2-yl)amino)butan-1-ol', '(2R)-2-((6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl)amino)butan-1-ol', '1-Butanol, 2-[[9-(1-methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-, (2R)-', 'DTXCID8094419', '186692-46-6', '(R)-roscovitine', 'CYC202', 'CYC-202', 'Roscovitine (Seliciclib,CYC202)', '(R)-2-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol', 'Seliciclib (Roscovitine)', 'MFCD02266401', 'CHEMBL14762', '0ES1C2KQ94', 'NSC701554', '(2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]amino]butan-1-ol', '(2R)-2-((6-benzylamino-9-(propan-2-yl)-9h-purin-2-yl)amino)butan-1-ol', 'RRC', 'Rosco', 'UNII-0ES1C2KQ94', '2-(1-ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine', 'BMK1-E12', '1unl', '3ddq', '2a4l', 'BiomolKI_000048', '1-Butanol, (2R)-', 'ROSCOVITINE(Seliciclib)', 'BiomolKI2_000054', 'M02443', 'ROSCOVITINE(Seliciclib)?', 'CBiol_002016', 'Lopac0_001102', 'SCHEMBL94728', 'BSPBio_001078', 'KBioGR_000418', 'KBioSS_000418', 'MLS006011028', 'BDBM7533', 'cid_160355', 'GTPL6035', 'Roscovitine, >=98% (TLC)', 'BCBcMAP01_000013', 'KBio2_000418', 'KBio2_002986', 'KBio2_005554', 'KBio3_000795', 'KBio3_000796', 'EX-A052', 'BCPP000087', 'Bio1_000302', 'Bio1_000791', 'Bio1_001280', 'Bio2_000379', 'Bio2_000859', 'CC205', 'GLXC-04786', 'HMS1362F19', 'HMS1792F19', 'HMS1990F19', 'HMS3229N13', 'HMS3403F19', 'BCP01760', 'Roscovitine (Seliciclib, CYC202)', 'HSCI1_000092', 'NSC800881', '6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine', 'AKOS005146319', 'AC-2416', 'CCG-100652', 'DB06195', 'NSC-800881', '2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol', 'IDI1_002134', 'Roscovitine - CAS 186692-46-6', 'SMP1_000266', '2,6,9-Trisubstituted purine deriv. 28', 'NCGC00094374-01', 'NCGC00094374-02', 'NCGC00094374-03', 'NCGC00094374-04', 'NCGC00094374-05', 'NCGC00094374-09', 'NCGC00094374-13', 'NCGC00094374-15', 'AS-56277', 'FR146851', 'HY-30237', 'NCI60_036420', 'SMR004702823', 'NS00068708', 'SW220195-1', 'K00020', 'EN300-26484982', 'Q3494619', 'BRD-K07691486-001-03-1', 'BRD-K07691486-001-05-6', 'BRD-K07691486-001-15-5', 'BRD-K07691486-001-19-7', 'Z1741982636', '(2R)-2-[[6-[(phenylmethyl)amino]-9-propan-2-yl-2-purinyl]amino]-1-butanol', '(2R)-2-[[6-[(phenylmethyl)amino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol', '2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]- 9H-purin-2-yl]amino]-(R)-1-butanol']","Type":"small molecule"},{"Action":"activate","PerturbationName":"Isoproterenol","PubChemCID":"3779","SMILES":"CC(C)NCC(C1=CC(=C(C=C1)O)O)O","Synonyms":"['isoproterenol', 'Isoprenaline', '7683-59-2', 'Isopropydrin', 'Asiprenol', 'Assiprenol', 'Bellasthman', 'Isoprenalin', 'Respifral', 'Aludrine', 'Asmalar', 'Neodrenal', 'Proternol', 'neo-Epinine', 'Isopropylarterenol', 'Isonorin', 'Saventrine', 'Isonorene', 'Lomupren', 'N-Isopropylnoradrenaline', 'Isopropyladrenaline', 'Isopropylnorepinephrine', 'N-Isopropylnorepinephrine', 'Isupren', 'Vapo-N-iso', 'Isopropylnoradrenaline', 'Isopropyl noradrenaline', 'dl-Isadrine', 'Racemic isoprenaline', 'Racemic isoproterenol', '(+-)-Isoproterenol', 'Isoprenalina', 'Isoprenalinum', 'Isoproterenolum', 'Epinephrine isopropyl homolog', '(+-)-Isoprenaline', '4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol', 'DL(+-)-Isoproterenol', 'Dihydroxyphenylethanolisopropylamine', 'WIN 5162', '1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol', 'ICI 46399', 'Isoprenalinum [INN-Latin]', 'Isoprenalina [INN-Spanish]', '1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol', 'alpha-(Isopropylaminomethyl)protocatechuyl alcohol', 'CCRIS 3081', '1,2-Benzenediol, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-', 'N-Isopropyl-beta-dihydroxyphenyl-beta-hydroxyethylamine', '4-(1-Hydroxy-2-((1-methylethyl)amino)ethyl)-1,2-benzenediol', 'NSC 9975', 'NSC-9975', '1,2-Benzenediol, 4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-', 'EINECS 231-687-7', 'NSC 33791', 'NSC-33791', 'UNII-L628TT009W', 'BRN 2213857', 'Isopropylaminomethyl-3,4-dihydroxyphenyl carbinol', 'Isoproterenol dl-form', 'DTXSID4023175', 'CHEBI:64317', 'L628TT009W', '3,4-Dihydroxy-alpha-((isopropylamino)methyl)benzyl alcohol', 'Protocatechuyl alcohol, alpha-(isopropylaminomethyl)-', 'DTXCID603175', '3-13-00-02387 (Beilstein Handbook Reference)', '3,4-dihydroxy-alpha-[(isopropylamino)methyl]benzyl alcohol', 'Benzyl alcohol, 3,4-dihydroxy-alpha-((isopropylamino)methyl)-', 'Isoprenalinum (INN-Latin)', 'Isoprenalina (INN-Spanish)', 'ISOPRENALINE (MART.)', 'ISOPRENALINE [MART.]', 'Noradrenaline, Isopropyl', '4-(1-hydroxy-2-(propan-2-ylamino)ethyl)benzene-1,2-diol', 'C01CA02', 'R03AB02', 'R03CB01', '231-687-7', 'Novodrin', 'Norisodrine', 'Aludrin', 'Isadrine', 'Isorenin', 'Bronkephrine', 'DL-ISOPROTERENOL', 'Aleudrin', 'Aleudrine', '149-53-1', 'Isoproterenol Chloride', 'Isoprenaline (INN)', 'Isoprenaline [INN]', '4-(1-Hydroxy-2-(isopropylamino)ethyl)benzene-1,2-diol', 'CHEMBL434', 'Isopropylaminomethyl(3,4-dihydroxyphenyl)carbinol', '7683-59-2 (free)', 'NSC33791', 'NCGC00015558-06', '3,4-Dihydroxy-.alpha.-(isopropylaminomethyl)-benzyl alcohol', 'A-21', 'Isoproterenol [JAN]', 'Protocatechuyl alcohol,-', '.alpha.-(Isopropylaminomoethyl)protocatechuyl alcohol', 'WLN: QR BQ DYQ1MY1&1', '3,4-Dihydroxy-.alpha.-[(isopropylamino)methyl]benzyl alcohol', '4-{1-hydroxy-2-[(1-methylethyl)amino]ethyl}benzene-1,2-diol', 'CAS-7683-59-2', 'ISOPROP', '1, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-', '4-[1-hydroxy-2-(isopropylamino)ethyl]benzene-1,2-diol', 'Benzyl alcohol,4-dihydroxy-.alpha.-[(isopropylamino)methyl]-', 'Isoproterenol-l', '3,4-DIHYDROXY-.ALPHA.-((ISOPROPYLAMINO)METHYL)BENZYL ALCOHOL', 'Isoproterenol (-)', 'Isoproterenol,(+)', 'ISOPROTERONOL', 'Isuprel (Salt/Mix)', 'Izadrin (Salt/Mix)', 'Euspiran (Salt/Mix)', 'L-Isoproterenol; Levisoprenaline; Proternol L', '(+/-)-isoprenaline', '(+/-)-isoproterenol', 'Spectrum_000949', 'Prestwick0_001097', 'Prestwick1_001097', 'Prestwick2_001097', 'Spectrum2_001061', 'Spectrum3_000474', 'Spectrum4_000024', 'Spectrum5_000880', '(.+/-.)-Isoprenaline', 'ISOPROTERENOL [MI]', '(.+/-.)-Isoproterenol', 'SCHEMBL4165', 'DL(.+/-.)-Isoproterenol', 'Lopac0_000711', 'Oprea1_009434', 'BSPBio_002208', 'GTPL536', 'ISOPROTERENOL [VANDF]', 'KBioGR_000427', 'KBioSS_001429', 'DivK1c_000894', 'ISOPRENALINE [WHO-DD]', 'SPBio_001042', 'SPBio_003057', 'SGCUT00015', '4-(1-Hydroxy-2(isopropylamino)ethyl)-benzene 1,2-diol', 'BDBM25392', 'KBio1_000894', 'KBio2_001429', 'KBio2_003997', 'KBio2_006565', 'KBio3_001428', 'NSC9975', 'NINDS_000894', '4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol', 'HMS2089A12', 'HMS3742A11', 'ISOPROTERENOL DL-FORM [MI]', 'BCP09043', 'to_000062', '(A+/-)-Isoproterenol hydrochloride', 'Tox21_110172', 'PDSP1_001425', 'PDSP2_001409', 'STL558077', 'AKOS015913894', 'Tox21_110172_1', 'CCG-204727', 'CCG-204796', 'DB01064', 'SDCCGSBI-0050620.P003', 'SDCCGSBI-0050689.P005', 'IDI1_000894', 'NCGC00015558-04', 'NCGC00015558-05', 'NCGC00015558-07', 'NCGC00015558-08', 'NCGC00015558-09', 'NCGC00015558-10', 'NCGC00015558-11', 'NCGC00015558-12', 'NCGC00015558-13', 'NCGC00015558-14', 'NCGC00015558-25', 'NCGC00016665-02', 'NCGC00025274-03', 'NCGC00025274-04', 'NCGC00162220-01', '114-45-4', 'TS-08150', 'SBI-0050689.P004', 'HY-108353', 'CS-0028436', 'NS00001320', 'C07056', 'D08090', 'EN300-148243', 'AB00053487-09', 'AB00053487-10', 'AB00053487_11', 'AB00053487_12', 'AG-219/03618046', 'L000936', 'Q415550', '.alpha.-(Isopropylaminomethyl)protocatechuyl alcohol', 'BRD-A04322457-003-15-3', 'BRD-A04322457-003-16-1', 'BRD-A04322457-003-17-9', 'BRD-A04322457-003-18-7', '4-[1-Hydroxy-2-(isopropylamino)ethyl]-1,2-benzenediol', 'Protocatechuyl alcohol,.alpha.-(isopropylamino-methyl),-', '4-[1-Hydroxy-2-(isopropylamino)ethyl]-1,2-benzenediol #', 'N-Isopropyl-.beta.-dihydroxyphenyl-.beta.-hydroxyethylamine', '4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride', '4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol, 2', 'Benzyl alcohol, 3,4-dihydroxy-.alpha.-((isopropylamino)methyl)-']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Taxol","PubChemCID":"36314","SMILES":"CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C","Synonyms":"['paclitaxel', 'TAXOL', '33069-62-4', 'Taxol A', 'Yewtaxan', 'Genaxol', 'Plaxicel', 'Ebetaxel', 'Genetaxyl', 'Capxol', 'Cyclopax', 'Genexol', 'Intaxel', 'Mitotax', 'TaxAlbin', 'EmPAC', 'Onxal', 'Zisu', 'Taxus stent', 'Taxus Liberte', 'Padexol', 'EndoTAG 1', 'Tocosol Paclitaxel', '(-)-Paclitaxel', 'Nanoxel', 'Paclitaxol', 'Sindaxel', 'Coroflex Please', 'Cypher select', 'Taxus Express', '(NAB)-Paclitaxel', 'MBT 0206', 'Infinnium', 'HSDB 6839', 'DHP 107', 'DHP-107', 'Abraxane I.V. Suspension', 'BMS 181339-01', 'BMS-181339-01', 'UNII-P88XT4IS4D', 'DRG-0190', 'P88XT4IS4D', 'NK 105', 'Paclitaxel (taxus canadensis)', 'QW 8184', 'CCRIS 8143', 'Liposome-entrapped paclitaxel easy-to-use', 'DTXSID9023413', 'CHEBI:45863', 'ABI-007 COMPONENT PACLITAXEL', 'IG 001', 'NK-105', '5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine', 'QW-8184', 'DTXCID603413', 'ORAXOL COMPONENT PACLITAXEL', 'Paclitaxel [USAN:USP:INN:BAN]', 'Abraxane (albumin-bound suspension)', 'ABRAXANE COMPONENT PACLITAXEL', 'ABI 007 COMPONENT PACLITAXEL', 'NAB-PACLITAXEL COMPONENT PACLITAXEL', 'PACLITAXEL (MART.)', 'PACLITAXEL [MART.]', 'PACLITAXEL (USP-RS)', 'PACLITAXEL [USP-RS]', 'PACLITAXEL (EP MONOGRAPH)', 'PACLITAXEL (USP IMPURITY)', 'PACLITAXEL [EP MONOGRAPH]', 'PACLITAXEL [USP IMPURITY]', 'PACLITAXEL (USP MONOGRAPH)', 'PACLITAXEL [USP MONOGRAPH]', 'Paclitaxel (USAN:USP:INN:BAN)', 'Bris Taxol', 'Taxol, Bris', 'paclitaxelum', '4alpha,10beta-bis(acetyloxy)-13alpha-((2S,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyloxy)-1,7beta-dihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate', '4alpha,10beta-bis(acetyloxy)-13alpha-[(2S,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyloxy]-1,7beta-dihydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate', 'PACLITAXELPACLITAXEL', 'L01CD01', 'Paclitaxel protein-bound particles for injectable suspension (albumin-bound)', '5-BETA,20-EPOXY-1,2-ALPHA,4,7-BETA,10-BETA,13-ALPHA-HEXAHYDROXY-TAX-11-EN-9-ONE 4,10-DIACETATE 2-BENZOATE 13-ESTER WITH (2R,3S)-N-BENZOYL-3-PHENYL-ISOSERINE', '5beta,20-Epoxy-1,2 alpha, 4,7beta, 10beta, 13alpha-hexahydroxy tax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R, 3S)-N-benzoyl-3-phenylisoserine', 'TAX-11-EN-9-ONE, 5-BETA,20-EPOXY-1,2-ALPHA,4,7-BETA,10-BETA,13-ALPHA-HEXA-HYDROXY-, 4,10-DIACETATE 2-BENZOATE 13-ESTER WITH (2R,3S)-N-BENZOYL-3-PHENYLISOSERINE', 'TAX-11-EN-9-ONE, 5BETA,20-EPOXY-1,2ALPHA,4,7BETA,10BETA,13ALPHA-HEXAHYDROXY-, 4,10-DIACETATE 2-BENZOATE 13-ESTER WITH (2R,3S)-N-BENZOYL-3-PHENYLISOSERINE', 'Tax-11-en-9-one, 5beta,20-epoxy-1,2alpha,4,7beta,10beta,13alpha-hexahydroxy-, 4,10-diacetate 2-benzoate, 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine', '(1s,2s,3r,4s,5r,7s,8s,10r,13s)-4,10-diacetoxy-2-benzoyloxy-5,20-epoxy-1,7-dihydroxy-9-oxotax-11-en-13-yl (2r,3s)-3-benzoylamino-2-hydroxy-3-phenylpropionate', 'Abraxane', 'Paxene', 'Onxol', 'OncoGel', 'Pacliex', 'Paxceed', 'ABI-007', 'LipoPac', 'NSC-125973', 'LEP-ETU', 'Genexol-PM', 'Taxus', 'ABI 007', 'Paclitaxel (Taxol)', 'MFCD00869953', 'NSC125973', 'CHEMBL428647', '(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b-diyl diacetate', 'nab-paclitaxel', 'MBT-0206', '7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.', '(2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha R*,betaS*),11alpha,12alpha,12balpha))-beta-(Benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester', 'NCGC00164367-01', 'NSC 125973', '(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^{3,10}.0^{4,7}]heptadec-13-en-2-yl benzoate', 'Anzatax', 'Cynviloq', 'Xorane', 'Taxol (Paclitaxel)', '[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate', 'SMR000857385', 'EndoTAG-1', 'SR-01000075350', 'Nanotaxel', 'Paclical', 'Pacligel', 'Paxoral', 'Paclitaxel?', 'Abraxane (TN)', '(2alpha,5beta,7beta,10beta,13alpha)-4,10-bis(acetyloxy)-1,7-dihydroxy-13-({(2R,3S)-2-hydroxy-3-phenyl-3-[(phenylcarbonyl)amino]propanoyl}oxy)-9-oxo-5,20-epoxytax-11-en-2-yl benzoate', '[diacetoxy-[(2R,3S)-3-benzamido-2-hydroxy-3-phenyl-propanoyl]oxy-dihydroxy-tetramethyl-oxo-[?]yl] benzoate', 'Paclitaxel; 5beta,20-Epoxy-1,7beta-dihydroxy-9-oxotax-11-ene-2alpha,4,10beta,13alpha-tetrayl 4,10-diacetate 2-benzoate 13-[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoate]; Taxol; Docetaxel Anhydrous Impurity F; Docetaxel Impurity F', 'CAS-33069-62-4', 'BMS-181339', 'Paclitaxel-SSMM-VIP', 'Paclitaxel (Standard)', 'P-SSMM-VIP', 'PACLITAXEL [MI]', 'PACLITAXEL [INN]', 'PACLITAXEL [JAN]', 'Prestwick3_000155', 'PACLITAXEL [HSDB]', 'PACLITAXEL [USAN]', 'TAXOL (TN)', 'PACLITAXEL [VANDF]', 'SCHEMBL3976', '3PPC5TL76P', 'Nova-12005', 'PACLITAXEL [WHO-DD]', 'Paclitaxel, Taxus brevifolia', 'BIDD:PXR0046', 'BSPBio_000290', 'KBioGR_002509', 'KBioSS_002517', 'Paclitaxel (JAN/USP/INN)', 'MLS002154218', 'MLS002695976', 'OAS-PAC-100', 'PACLITAXEL [EMA EPAR]', 'BPBio1_000320', 'GTPL2770', 'MEGxp0_001940', 'Taxol (TN) (Bristol Meyers)', 'PACLITAXEL [GREEN BOOK]', 'PACLITAXEL [ORANGE BOOK]', 'ACon1_002231', 'HY-B0015R', 'KBio2_002509', 'KBio2_005077', 'KBio2_007645', 'KBio3_002987', 'ANX-513', 'DHP-208', 'DTS-301', 'SDP-013', 'cMAP_000068', 'HMS2090D07', 'HMS2095O12', 'HMS2231A16', 'HMS3712O12', 'HY-B0015', 'MPI-5018', 'Tox21_112107', 'BDBM50001839', 'MSK000431', 'NSC745099', 'AKOS007930675', 'AKOS015969673', 'AKOS025312303', 'CCG-220155', 'CS-1145', 'DB01229', 'FP10637', 'GS-6554', 'NSC-745099', 'NCGC00164367-02', 'NCGC00164367-03', 'NCGC00164367-04', 'NCGC00164367-05', 'NCGC00164367-10', '(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-Dodecahydro-4,6,9,11,12,12b-hexahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca(3,4)benz(1,2-b)oxet-5-one 6,12b-diacetate, 12-benzoate, 9-ester with (2R,3S)-N-benzoyl-3-phenylisoserine', 'NCI60_000601', 'Paclitaxel, from Taxus yannanensis, powder', '1ST000431', 'PACLITAXEL IMPURITY L [EP IMPURITY]', 'AB00513812', 'D00491', 'EN300-117275', 'M02242', 'N88686', 'AB00513812-02', 'AB00513812-03', 'Q423762', '7,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.', 'SR-01000075350-1', 'SR-01000075350-3', 'SR-01000075350-6', 'SR-01000075350-7', 'SR-01000075350-9', 'BRD-K62008436-001-03-1', 'BRD-K62008436-001-05-6', 'BRD-K62008436-001-22-1', 'Paclitaxel, from semisynthetic (from Taxus sp.), >=97%', 'Paclitaxel, European Pharmacopoeia (EP) Reference Standard', 'Paclitaxel, from Taxus brevifolia, >=95% (HPLC), powder', 'Paclitaxel, United States Pharmacopeia (USP) Reference Standard', '12-benzoate, 9-ester with (2R,3S)-N-benzoyl-3-phenylisoserine', 'Paclitaxel, Pharmaceutical Secondary Standard; Certified Reference Material', 'Paclitaxel natural for peak identification, European Pharmacopoeia (EP) Reference Standard', '(1S,2S,3R,4S,5R,7S,8S,10R,13S)-4,10-Diacetoxy-2-benzoyloxy-5,20-epoxy-1,7-dihydroxy-9-oxotax-11-en-13-yl  (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropionate', '(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-Dodecahydro 4,6,9,11,12,12b-hexahydroxy-4a,8,13,13-tetramethyl-7,11-methano 5Hcyclodeca(3,4)benz(1,2-b)oxet-5-one 6,12b-diacetate,', '(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-4,6,12b-Tris(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl (alphaR,betaS)-beta-(benzoylamino)-alpha-hydroxybenzenepropanoate', '(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl (aR,bS)-b-(benzoylamino)-a-hydroxybenzenepropanoate', '(2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha R*,betaS*),11alpha,12alpha,12balpha))-beta-(Benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12', '(2beta,5beta,7alpha,8alpha,10alpha,13alpha)-4,10-bis(acetyloxy)-1,7-dihydroxy-13-({(2R,3S)-2-hydroxy-3-phenyl-3-[(phenylcarbonyl)amino]propanoyl}oxy)-9-oxo-5,20-epoxytax-11-en-2-yl benzoate', ',12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester', ',13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (alphaR,betaS)- (9CI)', '-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aalpha,4beta,4abeta,6beta,9alpha(aR*,betaS*),11alpha,12alpha,12aalpha,12balpha]]-', '[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4,12-diacetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9-dihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl]benzoate', '1203669-79-7', '4,7beta,10beta-tris(acetyloxy)-13alpha-[[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy]-1-hydroxy-9-oxo-5beta,20-epoxytax-11-en-2alpha-yl benzoate', 'BENZENEPROPANOIC ACID, .BETA.-(BENZOYLAMINO)-.ALPHA.-HYDROXY-, (2AR,4S,4AS,6R,9S,11S,12S,12AR,12BS)-6,12B-BIS(ACETYLOXY)-12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-4,11-DIHYDROXY-4A,8,13,13-TETRAMETHYL-5-OXO-7,11-METHANO-1H-CYCLODECA(3,4)BENZ(1,2-B)OXET-9-YL ESTER, (.ALPHA.R,.BETA.S)-', 'Benzenepropanoic acid, 6,12b-bis(acetyl oxy)-12-(benzoyloxy)- 2a,3,4,4a,5,6,9,10,11,12,12a,12b,- dodecahydro-4,11- dihydroxy-4a,8,13,13-tetramethyl-5-oxo- 7,11-methano- 1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR- [2a.alpha.,4.beta.,4a.beta.,6.beta.,9.alpha.(alpha. R*,.beta.S*),11.alpha.,12.alpha.,12a.alpha.,12b.alpha.]]-', 'Benzenepropanoic acid, b-(benzoylamino)-.alpha.-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (aR,bS)-', 'Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-4,6,12b-tris(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (alphaR,betaS)-', 'Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13', 'Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (alphaR,betaS)-', 'Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 4,6,12b-tris(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha]]-', 'Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H', 'Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2a-alpha,4-beta,4a-beta,6-beta,9-alpha(alpha-R*,beta-S*),11-alpha,12-alpha,12a-alpha, 12b-alpha))-', 'Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha))-', 'Paclitaxel semi-synthetic for peak identification, European Pharmacopoeia (EP) Reference Standard', 'Paclitaxel semi-synthetic for system suitability, European Pharmacopoeia (EP) Reference Standard', 'Tax-11-en-9-one, 5beta,20-epoxy-1,2alpha,4,7beta,10beta,13alpha- hexahydroxy-, 4,10-diacetate 2-benzoate, 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine', 'Tax-11-en-9-one, 5beta,20-epoxy-1,2alpha,4,7beta,10beta,13alpha-hexahydroxy-, 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine (8CI)', 'Tax-11-en-9-one,20-epoxy-1,2.alpha.,4,7.beta., 10.beta.,13.alpha.- hexahydroxy-, 4,10-diacetate 2- benzoate,13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Everolimus","PubChemCID":"6442177","SMILES":"C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OCCO)C)/C)O)OC)C)C)/C)OC","Synonyms":"['Everolimus', 'Afinitor', 'Certican', 'SDZ-RAD', '159351-69-6', '42-O-(2-Hydroxyethyl)rapamycin', 'Zortress', 'Votubia', 'RAD001', '40-O-(2-hydroxyethyl)-rapamycin', 'SDZ RAD', 'RAD-001', 'everolimusum', 'CHEBI:68478', '9HW64Q8G6G', 'DTXSID0040599', 'XIENCE V', 'RAD 666', 'RAD-666', 'Rapamycin, 42-O-(2-hydroxyethyl)-', 'UNII-9HW64Q8G6G', 'DTXCID8020599', 'HSDB 8255', 'NSC733504', 'EVEROLIMUS (MART.)', 'EVEROLIMUS [MART.]', 'EVEROLIMUS (USP-RS)', 'EVEROLIMUS [USP-RS]', '(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone', '(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone', 'EVEROLIMUS (EP MONOGRAPH)', 'EVEROLIMUS [EP MONOGRAPH]', 'RAD 001', '(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,35R)-1,18-dihydroxy-12-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0(4,9)]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone', 'AfinitorDisperz', '42-O-(2-Hydroxy)ethyl rapamycin', 'Everolimus tablets', '(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone', '(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,35R)-1,18-dihydroxy-12-((2R)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)propan-2-yl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-((2R)-1-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)propan-2-yl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido(2,1-c)(1,4)oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone', 'RAD, SDZ', 'L01XE10', 'L04AA18', '001, RAD', '40-O-(2-Hydroxyethyl)rapamycin', 'RAD', 'Afinitor Disperz', 'Everolimus (INN)', 'NCGC00167512-01', 'Everolimus (RAD001)', 'EVEROLIMUS [INN]', 'Everolimus (~90% pure)', 'Everolimus [USAN]', 'Everolimus?', 'EVE - Everolimus', 'Everolimus (Standard)', 'EVEROLIMUS [MI]', 'EVEROLIMUS [JAN]', 'EVEROLIMUS [VANDF]', 'SCHEMBL4378', 'EVEROLIMUS [WHO-DD]', 'EVEROLIMUS [EMA EPAR]', 'Everolimus [USAN:INN:BAN]', 'NVP-RAD-001', 'Everolimus, analytical standard', 'GTPL5889', 'RAD-001C', 'CHEMBL1908360', 'EVEROLIMUS [ORANGE BOOK]', 'Everolimus; RAD001; SDZ-RAD', '42-O-(2-Hydroxyethyl)-rapamycin', 'EX-A2057', 'Tox21_112510', 'BDBM50088378', 'Everolimus (RAD-001, SDZ-RAD)', 'HY-10218R', 'AKOS015850977', 'CS-0064', 'DB01590', 'FE23209', 'AS-16971', 'HY-10218', 'CAS-159351-69-6', '42-O-(2-Hydroxyethyl)rapamycin;RAD-001;SDZRAD', 'Q421052', 'BRD-K13514097-001-01-2', 'BRD-K13514097-001-05-3', '(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,2', 'dihydroxy-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxy-cyclohexyl]-1-methyl-ethyl]-dimethoxy-hexamethyl-[?]pentone']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"GDC0994","PubChemCID":"71727581","SMILES":"CN1C(=CC=N1)NC2=NC=CC(=N2)C3=CC(=O)N(C=C3)[C@H](CO)C4=CC(=C(C=C4)Cl)F","Synonyms":"['Ravoxertinib', 'GDC-0994', '1453848-26-4', 'GDC0994', '(S)-1-(1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one', 'RG-7842', 'Ravoxertinib [INN]', 'Ravoxertinib [USAN]', 'R6AXV96CRH', '1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one', '1-[(1S)-1-(4-CHLORO-3-FLUOROPHENYL)-2-HYDROXYETHYL]-4-{2-[(2-METHYLPYRAZOL-3-YL)AMINO]PYRIMIDIN-4-YL}PYRIDIN-2-ONE', '1-((1S)-1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)-4-pyrimidinyl)-2(1H)-pyridinone', '1-((1S)-1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin- 4-yl)pyridin-2(1H)-one', '1-[(1~{s})-1-(4-Chloranyl-3-Fluoranyl-Phenyl)-2-Oxidanyl-Ethyl]-4-[2-[(2-Methylpyrazol-3-Yl)amino]pyrimidin-4-Yl]pyridin-2-One', '2(1H)-Pyridinone, 1-((1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)-4-pyrimidinyl)-', '6QB', 'MFCD28143918', 'UNII-R6AXV96CRH', 'Ravoxertinib (USAN/INN)', 'Ravoxertinib [USAN:INN]', 'Ravoxertinib(GDC0994)?', 'Ravoxertinib (GDC-0994)', '(S)-1-(1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-(1-methyl-1H-pyrazol-5-ylamino)pyrimidin-4-yl)pyridin-2(1H)-one', 'RAVOXERTINIB [WHO-DD]', 'GTPL9229', 'CHEMBL3544964', 'SCHEMBL15245531', 'RZUOCXOYPYGSKL-GOSISDBHSA-N', 'BDBM120095', '(S)-1-[1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[2-[(1-methyl-5-pyrazolyl)amino]-4-pyrimidyl]-2(1H)-pyridone', '1-[(1S)-1-(4-chloro-3-fluoro-phenyl)-2-hydroxy-ethyl]-4-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]pyridin-2-one', 'BCP09668', 'EX-A1614', 'NSC781343', 'NSC800104', 'RG7842', 'AKOS027252126', 'CCG-269131', 'CS-3704', 'DB15281', 'NSC-781343', 'NSC-800104', 'example 39 [WO2013130976]', 'NCGC00386401-02', 'AC-33149', 'AS-55994', 'HY-15947', 'D11285', 'US8697715, 39', 'BRD-K86309810-001-01-5', 'Q27077782', '(S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-Me-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one', '1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-{2-[(1-methyl-1H-pyrazol-5-yl)amino]pyrimidin-4-yl}-1,2-dihydropyridin-2-one']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Go6976","PubChemCID":"3501","SMILES":"CN1C2=CC=CC=C2C3=C4C(=C5C6=CC=CC=C6N(C5=C31)CCC#N)CNC4=O","Synonyms":"['136194-77-9', 'Go 6976', 'GO6976', 'Go-6976', 'Goe 6976', '3-(13-Methyl-5-oxo-6,7-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-12(13H)-yl)propanenitrile', 'B9IQO7JZ16', '12-(2-Cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole', 'CHEMBL302449', 'CHEBI:51913', '12H-Indolo(2,3-a)pyrrolo(3,4-c)carbazole-12-propanenitrile, 5,6,7,13-tetrahydro-13-methyl-5-oxo-', '12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile, 5,6,7,13-tetrahydro-13-methyl-5-oxo-', '12-(2-cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo[2,3-a]pyrolo[3,4-c]carbazole', '3-(13-methyl-5-oxo-5,6,7,13-tetrahydro-12H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-12-yl)propanenitrile', 'UNII-B9IQO7JZ16', 'Goe-6976', 'Kinome_3630', 'Gouml 6976', 'G ouml 6976', 'CBiol_001871', 'G? 6976', 'BSPBio_001101', 'KBioGR_000441', 'KBioSS_000441', '13-Methyl-5-oxo-5,6,7,13-tetrahydro-12H-indolo(2,3-a)pyrrolo(3,4-c)carbazole-12-propanenitrile', 'BDBM3033', 'GTPL5973', 'SCHEMBL2175239', 'BCBcMAP01_000156', 'KBio2_000441', 'KBio2_003009', 'KBio2_005577', 'KBio3_000821', 'KBio3_000822', 'DTXSID70159731', 'Bio1_000157', 'Bio1_000646', 'Bio1_001135', 'Bio2_000381', 'Bio2_000861', 'GLXC-03625', 'HMS1362G03', 'HMS1792G03', 'HMS1990G03', 'HMS3229E13', 'HMS3403G03', 'BCP06797', '3-[methyl(oxo)[?]yl]propanenitrile', 'EI-269', 'HB0302', 'MFCD00236434', 's7119', 'AKOS024457007', 'AT23580', 'CCG-206755', 'SDCCGSBI-0086678.P003', 'Go6976 (PD40697)', 'IDI1_002136', 'NCGC00163451-01', 'NCGC00163451-02', 'NCGC00163451-03', 'NCGC00163451-04', 'AS-16804', 'BG168444', 'DA-63859', 'GO 6976?', 'HY-10183', 'PD406976', 'CS-0002498', 'G?? 6976, >=98% (HPLC), powder', 'Go 6976 - CAS 136194-77-9', 'BRD-K59304176-001-02-5', 'BRD-K59304176-001-03-3', 'Q27077832', '12-(2-Cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole;5,6,7,13-Tetrahydro-13-methyl-5-oxo-1 2H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propanenitrile', '3-(23-methyl-14-oxo-3,13,23-triazahexacyclo[14.7.0.0^{2,10.0^{4,9.0^{11,15.0^{17,22]tricosa-1,4,6,8,10,15,17,19,21-nonaen-3-yl)propanenitrile', '3-(23-methyl-14-oxo-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4,6,8,10,15,17,19,21-nonaen-3-yl)propanenitrile', '3-{23-methyl-14-oxo-3,13,23-triazahexacyclo[14.7.0.0(2),(1)?.0?,?.0(1)(1),(1)?.0(1)?,(2)(2)]tricosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaen-3-yl}propanenitrile', '3-{23-methyl-14-oxo-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17,19,21-nonaen-3-yl}propanenitrile', '3-{23-methyl-14-oxo-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4,6,8,11(15),17,19,21-nonaen-3-yl}propanenitrile', '5,6,7,13-Tetrahydro-13-methyl-5-oxo--12H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-12-propa-nenitrile']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Ro4929097","PubChemCID":"49867930","SMILES":"CC(C)(C(=O)NCC(C(F)(F)F)(F)F)C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3NC1=O","Synonyms":"['RO4929097', 'RO-4929097', 'RG-4733', 'Ro 4929097', 'UNII-KK8645V7LE', 'KK8645V7LE', 'Rg 4733', 'RG4733', 'CHEBI:86474', 'DTXSID20233833', 'RG 4733 [WHO-DD]', '2,2-dimethyl-N(1)-[(7S)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-N(3)-(2,2,3,3,3-pentafluoropropyl)propanediamide', \"2,2-dimethyl-N-[(10S)-9-oxo-8-azatricyclo[9.4.0.02,7]pentadeca-1(15),2,4,6,11,13-hexaen-10-yl]-N'-(2,2,3,3,3-pentafluoropropyl)propanediamide\", 'PROPANEDIAMIDE, N1-((7S)-6,7-DIHYDRO-6-OXO-5H-DIBENZ(B,D)AZEPIN-7-YL)-2,2-DIMETHYL-N3-(2,2,3,3,3-PENTAFLUOROPROPYL)-', \"2,2-dimethyl-N'-((10S)-9-oxo-8-azatricyclo(9.4.0.0^(2,7))pentadeca-1(15),2,4,6,11,13-hexaen-10-yl)-N-(2,2,3,3,3-pentafluoropropyl)propanediamide\", \"2,2-dimethyl-N'-[(10S)-9-oxo-8-azatricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2,4,6,11,13-hexaen-10-yl]-N-(2,2,3,3,3-pentafluoropropyl)propanediamide\", '2,2-dimethyl-N(1)-((7S)-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N(3)-(2,2,3,3,3-pentafluoropropyl)propanediamide', \"2,2-dimethyl-N-((10S)-9-oxo-8-azatricyclo(9.4.0.02,7)pentadeca-1(15),2,4,6,11,13-hexaen-10-yl)-N'-(2,2,3,3,3-pentafluoropropyl)propanediamide\", 'DTXCID50156324', 'Gamma-Secretase Inhibitor RO4929097', 'R04929097', '847925-91-1', 'N1-[(7S)-6,7-dihydro-6-oxo-5H-dibenz[b,d]azepin-7-yl]-2,2-dimethyl-N3-(2,2,3,3,3-pentafluoropropyl)propanediamide', '(S)-2,2-dimethyl-N1-(6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N3-(2,2,3,3,3-pentafluoropropyl)malonamide', \"Propanediamide, N-((7S)-6,7-dihydro-6-oxo-5H-dibenz(b,d)azepin-7-yl)-2,2-dimethyl-N'-(2,2,3,3,3-pentafluoropropyl)-\", 'Ro492097', 'R-4733', 'MLS006011071', 'GTPL7338', 'SCHEMBL1376366', 'CHEMBL4297422', 'BCPP000088', 'EX-A1750', 'BDBM50533417', 'NSC756650', 'AKOS027250816', 'CS-0480', 'DB11870', 'FR65150', 'NSC-756650', 'NCGC00263162-01', 'NCGC00263162-02', 'NCGC00263162-12', 'AC-33058', 'AS-74989', 'DA-77512', 'HY-11102', 'SMR004702861', 'NS00072583', 'RO4929097?', 'C76705', 'BRD-K22024824-001-03-7', 'Q27088591', \"2,2-dimethyl-N'-[(10S)-9-oxo-8-azatricyclo[9.4.0.0(2),?]pentadeca-1(11),2(7),3,5,12,14-hexaen-10-yl]-N-(2,2,3,3,3-pentafluoropropyl)propanediamide\", \"2,2-dimethyl-N'-[(10S)-9-oxo-8-azatricyclo[9.4.0.0(2),?]pentadeca-1(11),2,4,6,12,14-hexaen-10-yl]-N-(2,2,3,3,3-pentafluoropropyl)propanediamide\", \"2,2-DIMETHYL-N'-[(10S)-9-OXO-8-AZATRICYCLO[9.4.0.0(2),?]PENTADECA-1(15),2,4,6,11,13-HEXAEN-10-YL]-N-(2,2,3,3,3-PENTAFLUOROPROPYL)PROPANEDIAMIDE\", \"2,2-dimethyl-N-((S)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N'-(2,2,3,3,3-pentafluoro-propyl)-malonamide\", \"N-((7S)-6,7-Dihydro-6-oxo-5H-dibenz(b,d)azepin-7-yl)-2,2-dimethyl-N'-(2,2,3,3,3-pentafluoropropyl)-propanediamide\"]","Type":"small molecule"},{"Action":"not found","PerturbationName":"Ly","PubChemCID":"70410","SMILES":"CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O)N","Synonyms":"['968-21-8', 'Leucyltyrosine', 'leucyl-tyrosine', 'Leu-Tyr', 'CHEBI:73591', 'EINECS 213-527-8', '(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid', 'NSC 118372', 'LY dipeptide', 'L-Y Dipeptide', 'Leucine Tyrosine dipeptide', 'Leucine-Tyrosine dipeptide', 'DTXSID10874719', '(2S)-2-(((2S)-2-amino-4-methylpentanoyl)amino)-3-(4-hydroxyphenyl)propanoic acid', '(2S)-2-(((2S)-2-azaniumyl-4-methylpentanoyl)amino)-3-(4-hydroxyphenyl)propanoate', '(2S)-2-[[(2S)-2-azaniumyl-4-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoate', '2-((2-Amino-1-hydroxy-4-methylpentylidene)amino)-3-(4-hydroxyphenyl)propanoate', '2-[(2-Amino-1-hydroxy-4-methylpentylidene)amino]-3-(4-hydroxyphenyl)propanoate', '(2s)-2-(((2s)-2-amino-1-hydroxy-4-methylpentylidene)amino)-3-(4-hydroxyphenyl)propanoic acid', '(2s)-2-{[(2s)-2-amino-1-hydroxy-4-methylpentylidene]amino}-3-(4-hydroxyphenyl)propanoic acid', 'DTXCID401012844', 'lhsgpcfbgjhpcy-uhfffaoysa-n', 'nocas_874719', 'L-LEUCYL-L-TYROSINE', '(S)-2-((S)-2-Amino-4-methylpentanamido)-3-(4-hydroxyphenyl)propanoic acid', 'CHEMBL56099', '(2S)-2-[(2S)-2-amino-4-methylpentanamido]-3-(4-hydroxyphenyl)propanoic acid', 'H-Leu-Tyr-OH', 'Tyrosine, leucyl-', 'N-L-Leucyl-L-tyrosine', 'MFCD00020195', 'L-Leu-L-Tyr', 'SCHEMBL2474675', 'LHSGPCFBGJHPCY-STQMWFEESA-N', 'DTXSID301317217', 'LY', 'BDBM50348865', 'AKOS010367110', 'AKOS015853930', 'AS-73052', 'L0040', 'NS00042492', 'T73104', 'Q27141905', 'L-Y']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"KN62","PubChemCID":"5312126","SMILES":"CN([C@@H](CC1=CC=C(C=C1)OS(=O)(=O)C2=CC=CC3=C2C=CN=C3)C(=O)N4CCN(CC4)C5=CC=CC=C5)S(=O)(=O)C6=CC=CC7=C6C=CN=C7","Synonyms":"['KN-62', '127191-97-3', 'KN62', '(S)-4-(2-(N-methylisoquinoline-5-sulfonamido)-3-oxo-3-(4-phenylpiperazin-1-yl)propyl)phenyl isoquinoline-5-sulfonate', 'KN 62', 'CHEMBL28324', 'MFCD00083180', '63HM46XPOW', '1-[N,O-bis(5-Isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazine', '[4-[(2S)-2-[isoquinolin-5-ylsulfonyl(methyl)amino]-3-oxo-3-(4-phenylpiperazin-1-yl)propyl]phenyl] isoquinoline-5-sulfonate', '1-(N,O-Bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl)-4-phenylpiperazine', '(S)-5-Isoquinolinesulfonic acid 4-[2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenyl ester', '1-[N,O-Bis(5-Isoquinolinesulfonyl)-N-Methyltyrosyl]-4-Phenylpiperazine', 'SMR000058456', 'UNII-63HM46XPOW', 'KN62 (S isomer)', 'CBiol_002006', 'Lopac0_000620', 'MLS000028868', 'MLS006011204', 'SCHEMBL379481', 'GTPL4235', 'KN-62, >=95%, powder', 'CHEBI:131159', 'Bio1_000292', 'Bio1_000781', 'Bio1_001270', 'GLXC-04616', 'HMS2235I16', 'HMS3648M08', 'HMS3886F15', 'BCP02708', 'EX-A2396', 'BDBM50087267', 'HB0359', 'KN-62?', 's7422', 'AKOS005145990', 'CCG-270407', 'CS-0516', 'FB24811', 'SDCCGSBI-0086769.P003', 'SDCCGSBI-0654267.P001', 'NCGC00162398-01', 'NCGC00162398-02', 'NCGC00162398-03', 'NCGC00162398-04', 'NCGC00162398-11', '5-Isoquinolinesulfonic acid, 4-(2-((5-isoquinolinylsulfonyl)methylamino)-3-oxo-3-(4-phenyl-1-piperazinyl)propyl)phenyl ester, (S)-', 'AC-27760', 'HY-13290', 'SW219945-1', 'C72130', 'SR-01000721938', 'KN-62 - CAS 127191-97-3', 'SR-01000721938-2', 'Q18386454', '1-[ N,O-Bis(5-isoquinolinesulfonyl)-N-methyltyrosyl]-4-phenylpiperazine', '1-[N,O-Bis(5-isoquinolinesulfonyl)N-methyltyrosyl]-4-phenylpiperazine', '(1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl)-4phenylpiperazine)', '[(1-[N,O-bis(5-isoquinolinesulphonyl)-N-methyl-Ltyrosyl]-4-phenylpiperazine)', '1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl)-4-phenylpiperazine', '(S)-5-isoquinolinesulfonic acid 4-(2-[(5-isoquinolinylsulfonyl)methylamino]- 3-oxo-3-[4-phenyl-1-piperazinyl]propyl)phenyl ester;1-(  N,O-Bis-[5-isoquinolinesulfonyl]-N-methyl-L-tyrosyl)-4-phenylpiperazine', '[4-[(2S)-2-[5-isoquinolylsulfonyl(methyl)amino]-3-oxo-3-(4-phenylpiperazin-1-yl)propyl]phenyl] isoquinoline-5-sulfonate', '4-[(2S)-2-(N-methylisoquinoline-5-sulfonamido)-3-oxo-3-(4-phenylpiperazin-1-yl)propyl]phenyl isoquinoline-5-sulfonate', 'Isoquinoline-5-sulfonic acid 4-[(S)-2-[(isoquinoline-5-sulfonyl)-methyl-amino]-3-oxo-3-(4-phenyl-piperazin-1-yl)-propyl]-phenyl ester']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"HS173","PubChemCID":"52936849","SMILES":"CCOC(=O)C1=CN=C2N1C=C(C=C2)C3=CC(=CN=C3)NS(=O)(=O)C4=CC=CC=C4","Synonyms":"['HS-173', '1276110-06-5', '2758X982JL', 'Imidazo[1,2-a]pyridine-3-carboxylic acid, 6-[5-[(phenylsulfonyl)amino]-3-pyridinyl]-, ethyl ester', 'ethyl 6-[5-(benzenesulfonamido)pyridin-3-yl]imidazo[1,2-a]pyridine-3-carboxylate', 'Imidazo(1,2-a)pyridine-3-carboxylic acid, 6-(5-((phenylsulfonyl)amino)-3-pyridinyl)-, ethyl ester', 'ethyl 6-(5-(benzenesulfonamido)pyridin-3-yl)imidazo(1,2-a)pyridine-3-carboxylate', 'Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate', 'CHEMBL1765463', 'HS173', 'ethyl 6-(5-benzenesulfonamidopyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate', 'MFCD28023584', 'GTPL8243', 'SCHEMBL20768095', 'UNII-2758X982JL', 'EX-A320', 'GLXC-05936', 'HMS3653I16', 'BBC11006', 'BCP09225', 'BDBM50341493', 's7356', 'AKOS026750419', 'CCG-268913', 'CS-6015', 'HS-173?', 'SB19242', 'Ethyl 6-(5-(Phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]-pyridine-3-carboxylate', 'NCGC00386329-02', 'NCGC00386329-06', 'AC-35309', 'AS-74644', 'DA-36979', 'HY-15868', 'SW219873-1', 'EN300-202619', 'Q27077993', 'Z1939360435', 'Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine -3-carboxylate', 'ethyl 6-[5-(benzenesulfonamido)-3-pyridyl]imidazo[1,2-a]pyridine-3-carboxylate']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Selumetinib","PubChemCID":"10127622","SMILES":"CN1C=NC2=C1C=C(C(=C2F)NC3=C(C=C(C=C3)Br)Cl)C(=O)NOCCO","Synonyms":"['Selumetinib', '606143-52-6', 'ARRY-142886', '5-[(4-BROMO-2-CHLOROPHENYL)AMINO]-4-FLUORO-N-(2-HYDROXYETHOXY)-1-METHYL-1H-BENZIMIDAZOLE-6-CARBOXAMIDE', 'ARRY 142886', 'ARRY-886', 'selumetinibum', 'UNII-6UH91I579U', '6UH91I579U', 'ARRY142886', 'DTXSID3048944', 'CHEBI:90227', 'DTXCID0028870', 'NSC 741O78', '1H-Benzimidazole-6-carboxamide, 5-((4-bromo-2-chlorophenyl)amino)-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-', '5-((4-BROMO-2-CHLOROPHENYL)AMINO)-4-FLUORO-N-(2-HYDROXYETHOXY)-1-METHYL-1H-BENZIMIDAZOLE-6-CARBOXAMIDE', 'MEK inhibitor AZD6244', 'AZD6244', 'AZD 6244', 'AZD-6244', 'Selumetinib (AZD6244)', '5-((4-bromo-2-chlorophenyl)amino)-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzo[d]imidazole-6-carboxamide', 'Selumetinib [USAN:INN]', 'Koselugo', 'CHEMBL1614701', 'NSC741078', 'NCGC00189073-01', 'NCGC00189073-02', '6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide', 'AZD6244 (Selumetinib)', '5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-1,3-benzodiazole-6-carboxamide', '6-[(4-bromo-2-chlorophenyl)amino]-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide', 'AZD 6244;5-((4-Bromo-2-chlorophenyl)amino)-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzo[d]imidazole-6-carboxamide;6-(4-bromo-2-chlorophenylamino)-7-fluoro-N-(2-hydroxyethoxy)-3-methyl-3H-benzo[d]imidazole-5-carboxamide', 'CAS-606143-52-6', 'C17H15BrClFN4O3', '5-(4-broMo-2-chlorophenylaMino)-4-fluoro-N-(2-hydroxyethoxy)-1-Methyl-1H-benzo[d]iMidazole-6-carboxaMide', '3EW', 'MFCD11977472', 'SELUMETINIB [MI]', 'SELUMETINIB [INN]', 'Selumetinib (USAN/INN)', 'SELUMETINIB [USAN]', 'SELUMETINIB [WHO-DD]', 'SCHEMBL155456', 'GTPL5665', 'EX-A020', 'CYOHGALHFOKKQC-UHFFFAOYSA-N', 'BCPP000367', 'HMS3244G03', 'HMS3244G04', 'HMS3244H03', 'HMS3265K01', 'HMS3265K02', 'HMS3265L01', 'HMS3265L02', 'HMS3654O03', 'BCP01739', 'Tox21_113362', 'BDBM50355497', 'NSC800882', 's1008', 'AKOS015904255', 'Tox21_113362_1', 'BCP9000354', 'CCG-264774', 'CS-0059', 'DB11689', 'EX-8621', 'FS27812', 'NSC-741078', 'NSC-800882', 'SB14707', 'SDCCGSBI-0654324.P001', 'NCGC00189073-07', '6-(4-bromo-2-chloro-anilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methyl-benzimidazole-5-carboxamide', 'AC-25059', 'AZD6244,Selumetinib, ARRY-142886', 'HY-50706', 'Selumetinib (ARRY142886/AZD6244)', 'AZD6244 (Selumetinib,ARRY-142886)?', 'NS00071922', 'SW202561-3', 'D09666', 'EN300-18166787', 'Q7448840', 'BRD-K57080016-001-01-9', 'BRD-K57080016-001-15-9', 'BRD-K57080016-001-19-1', '1H-BENZIMIDAZOLE-6-CARBOXAMIDE, 5-((4-BROMO-2-CHLOROPHENYL)AMINO)-4-FLUORO-N-(2- HYDROXYETHOXY)-1-METHYL-', '6-(4-bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy -ethoxy)-amide', '6-(4-Bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide', '6-(4-bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid(2-hydroxy-ethoxy)-amide', '6-(4-bromo-2-chlorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxyethoxy)-amide', '6-(4-bromo-2-chlorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid(2-hydroxyethoxy)-amide', '6-(4-bromo-2chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Vx","PubChemCID":"39793","SMILES":"CCOP(=O)(C)SCCN(C(C)C)C(C)C","Synonyms":"['VX nerve agent', 'VX agent', 'CHEBI:136185', 'Phosphonothioic acid, methyl-, S-(2-(bis(1-methylethyl)amino)ethyl) O-ethyl ester', 'Phosphonothioic acid, P-methyl-, S-(2-(bis(1-methylethyl)amino)ethyl) O-ethyl ester', 'O-ethyl-S-[2-(N,N-diisopropylamino)ethyl] ester', 'O-Ethyl S-(2-diisopropylaminoethyl) methylthiophosphonate', 'S-{2-[di(propan-2-yl)amino]ethyl} O-ethyl methylphosphonothioate', 'Phosphonothioic acid, methyl-, S-[2-[bis(1-methylethyl)amino]ethyl] O-ethyl ester', 'O-ethyl-S-(2-(N,N-diisopropylamino)ethyl) ester', 'S-(2-(di(propan-2-yl)amino)ethyl) O-ethyl methylphosphonothioate', 'S-(2-(DIISOPROPYLAMINO)ETHYL) O-ETHYL METHYLPHOSPHONOTHIOLATE', 'S-[2-(DIISOPROPYLAMINO)ETHYL] O-ETHYL METHYLPHOSPHONOTHIOLATE', 'Phosphonothioic acid, P-methyl-, S-[2-[bis(1-methylethyl)amino]ethyl] O-ethyl ester', 'VX VAPOR', 'o-ethyl s-diisopropylaminoethyl methylphosphonothioate', 's-2-diisopropylaminoethyl o-ethyl methylphosphonothioate', 'ETHYL S-DIMETHYLAMINO-ETHYL METHYLPHOSPHONOTHIOLATE', 'PHOSPHONOTHIOIC ACID, METHYL-, S-(2-(BIS(1-METHYLETHYL', 'S-(2-DIISOPROPYLAMINOETHYL) O-ETHYL METHYLPHOSPHONOTHIOLATE', '50782-69-9', 'Tx 60', 'VX', 'O-Ethyl S-(2-diisopropylaminoethyl) methylphosphonothioate', 'Ethyl-S-diisopropylaminoethyl methylthiophosphonate', 'BRN 1949015', 'Ethyl S-2-diisopropylaminoethyl methylphosphonothiolate', 'Methylphosphonothioic acid S-(2-(bis(1-methylethyl)amino)ethyl) O-ethyl ester', 'CHEMBL483105', 'S-(2-Diisopropylaminoethyl) O-ethyl methyl phosphonothiolate', 'S-(2-Diisopropylaminoethyl)-O-ethyl methylphosphonothiolate', '9A4381183B', 'O-ethyl S-2-diisopropylaminoethyl methylphosphonothioate', 'VX (van)', 'agent VX', 'CCRIS 3351', 'HSDB 6459', 'EA 1701', 'O-Ethyl S-(2-diisopropylaminoethyl)methylphosphonothioate', 'UNII-9A4381183B', 'Ethyl S-dimethylaminoethyl methylphosphonothiolate', '65167-64-8', '(R)-S-(2-(Bis(1-methylethyl)amino)ethyl) O-ethyl methylphosphonothioate', '(S)-S-(2-(Bis(1-methylethyl)amino)ethyl) O-ethyl methylphosphonothioate', 'Methylphosphonothioic acid, S-(2-diisopropylamino)ethyl O-ethyl ester', 'VX [HSDB]', '(+-)-S-(2-(Bis(1-methylethyl)amino)ethyl) O-ethyl methylphosphonothioate', 'Methylphosphonothioic acid S-(2-(bis(methylethyl)amino)ethyl) O-ethyl ester', 'O-Ethyl-S-2-diisopropylaminoethylester kyseliny methylthiofosfonove [Czech]', 'Phosphonothioic acid, methyl-, S-(2-(bis(1-methylethyl)amino)ethyl) O-ethyl ester, (+)-', 'Phosphonothioic acid, methyl-, S-(2-(bis(1-methylethyl)amino)ethyl) O-ethyl ester, (-)-', 'VX [MI]', 'SCHEMBL215425', 'DTXSID80866161', 'O-Ethyl S-2-diisopropylaminoethyl methyl phosphonothiolate', 'BDBM50027342', 'O-Ethyl-S-2-diisopropylaminoethylester kyseliny methylthiofosfonove', 'N-[2-[ethoxy(methyl)phosphoryl]sulfanylethyl]-N-propan-2-ylpropan-2-amine', 'Phosphonothioic acid, methyl-, S-(2-(diisopropylamino)ethyl) O-ethyl ester', 'Phosphonothioic acid, methyl-, S-(2-(bis(1-methylethyl)amino)ethyl) O-ethyl ester, (+-)-', '65167-63-7', 'PD193129', 'VX.', 'NS00075528', 'Q421809', 'O-Ethyl S-2-diisopropylaminoethyl methylphosphonothiolate', 'o-ethyl s-(2-(diisopropylamino)ethyl)methylphosphonothioate', 'o-ethyl s-[2-(diisopropylamino)ethyl] methylphosphonothioate', 'S-[2-(Diisopropylamino)ethyl] o-ethyl methylphosphonothioate', 'Methyl-phosphonothioic acid S-(2-diisopropylamino-ethyl) ester O-ethyl ester', 'Phosphonohioic acid, methyl, O-ethyl-S-(2-diisopropylaminoethyl) ester']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Bafilomycin a1","PubChemCID":"6436223","SMILES":"C[C@H]1C/C(=C/C=C/[C@@H]([C@H](OC(=O)/C(=C/C(=C/[C@H]([C@H]1O)C)/C)/OC)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)C(C)C)C)O)O)O)OC)/C","Synonyms":"['bafilomycin A1', '88899-55-2', 'CHEBI:22689', 'NSC 381866', '(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-{(2S,3R,4S)-4-[(2R,4R,5S,6R)-2,4-dihydroxy-6-isopropyl-5-methyltetrahydro-2H-pyran-2-yl]-3-hydroxypentan-2-yl}-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one', 'Hygrolidin, 21-O-de(3-carboxy-1-oxo-2-propenyl)-2-demethyl-2-methoxy-24-methyl-', 'DTXSID201015547', '(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-((2S,3R,4S)-4-((2R,4R,5S,6R)-2,4-dihydroxy-6-isopropyl-5-methyltetrahydro-2H-pyran-2-yl)-3-hydroxypentan-2-yl)-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one', 'DTXCID801473810', '(3z,5e,11e,13e)-16-(4-(2,4-dihydroxy-5-methyl-6-propan-2-yloxan-2-yl)-3-hydroxypentan-2-yl)-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one', '(3z,5e,11e,13e)-16-[4-(2,4-dihydroxy-5-methyl-6-propan-2-yloxan-2-yl)-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one', 'MFCD06795130', 'CHEMBL290814', 'BafA1', 'NSC381866', 'Bafilomycin A1 from Streptomyces griseus', 'BSPBio_001470', 'MEGxm0_000385', 'SCHEMBL13775181', 'ACon0_000813', 'XDHNQDDQEHDUTM-JQWOJBOSSA-N', 'HMS3402J12', 'BDBM50064186', 'HB1125', 'AKOS030213158', 'AT13632', 'DB06733', 'NCGC00163426-02', '(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(2S,3R,4S)-4-[(2R,4R,5S,6R)-2,4-dihydroxy-5-methyl-6-propan-2-yloxan-2-yl]-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one', 'FB146475', 'Q4841341', '(3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-2,4-dihydroxy-6-isopropyl-5-methyl-tetrahydropyran-2-yl]-2-hydroxy-1-methyl-butyl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Carfilzomib","PubChemCID":"11556711","SMILES":"CC(C)C[C@@H](C(=O)[C@]1(CO1)C)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC3=CC=CC=C3)NC(=O)CN4CCOCC4","Synonyms":"['Carfilzomib', '868540-17-4', 'UNII-72X6E3J5AR', 'NSC-758252', '72X6E3J5AR', 'DTXSID4048690', 'CHEBI:65347', 'DTXCID0028616', 'NSC 758252', 'N-{(2S)-2-[(morpholin-4-ylacetyl)amino]-4-phenylbutanoyl}-L-leucyl-N-{(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl}-L-phenylalaninamide', '(2S)-N-((1S)-1-Benzyl-2-(((1S)-3-methyl-1-(((2R)-2-methyloxiran-2-yl)carbonyl)butyl)amino)-2-oxoethyl)-4-methyl-2-(((2S)-2-((morpholin-4-ylacetyl)amino)-4-phenylbutanoyl)amino)pentanamide', 'L-Phenylalaninamide, (alphaS)-alpha-((4-morpholinylacetyl)amino)benzenebutanoyl-L-leucyl-N-((1S)-3-methyl-1-(((2R)-2-methyloxiranyl)carbonyl)butyl)-', 'carfilzomibum', '(2S)-N-[(1S)-1-Benzyl-2-[[(1S)-3-methyl-1-[[(2R)-2-methyloxiran-2-yl]carbonyl]butyl]amino]-2-oxoethyl]-4-methyl-2-[[(2S)-2-[(morpholin-4-ylacetyl)amino]-4-phenylbutanoyl]amino]pentanamide', 'N-((2S)-2-((morpholin-4-ylacetyl)amino)-4-phenylbutanoyl)-L-leucyl-N-((2S)-4-methyl-1-((2R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)-L-phenylalaninamide', 'L01XX45', 'N-((2S)-2-((Morpholin-4-ylacetyl)amino)-4-phenylbutanoyl)-L-leucyl-L-phenylalanin-N-((2S)-4-methyl-1-((2R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amide', 'Kyprolis', 'Carfilzomib (PR-171)', 'PR-171', 'Carfilzomib (PR171)', 'CHEMBL451887', '(alphaS)-alpha-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide', 'NCGC00249613-01', '(2S)-4-methyl-N-[(2S)-1-[[(2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]-4-phenylbutanoyl]amino]pentanamide', '(S)-4-methyl-N-((S)-1-((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide', 'C40H57N5O7', 'MFCD11040997', '(S)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide', 'Carfilzomib [USAN]', 'CAS-868540-17-4', 'Carfilzomib [USAN:INN]', 'Kyprolis (TN)', 'Carfilzomib; PR171', 'Carfilzomib (Standard)', 'CARFILZOMIB [MI]', 'CARFILZOMIB [INN]', 'CARFILZOMIB [JAN]', 'CARFILZOMIB [VANDF]', 'Carfilzomib (PR-171)?', 'SCHEMBL85165', 'CARFILZOMIB [WHO-DD]', 'MLS006011102', 'Carfilzomib (JAN/USAN/INN)', 'GTPL7420', 'CARFILZOMIB [ORANGE BOOK]', 'BLMPQMFVWMYDKT-NZTKNTHTSA-N', 'EX-A2037', 'ONO-7057', 'Tox21_113079', 'BDBM50277889', 'HY-10455R', 'NSC756640', 'NSC758252', 's2853', 'AKOS025401910', 'Tox21_113079_1', 'CCG-270405', 'CS-0984', 'CS-W004540', 'DB08889', 'FC46443', 'NSC-756640', 'NCGC00249613-02', 'NCGC00249613-03', 'NCGC00249613-08', 'NCGC00249613-11', 'NCGC00249613-13', '(S)-4-Methyl-N-((S)-1-((S)-4-Methyl-1-((R)-2- Methyloxiran-2-yl)-1 -oxopentan-2-ylaMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide', 'AC-27051', 'AS-17059', 'HY-10455', 'SMR004660024', 'NS00072616', 'SW218090-2', 'D08880', 'AB01565867_02', 'SR-01000941582', 'SR-01000941582-1', 'BRD-K15179879-001-03-2', 'Q15366934', '(|AS)-|A-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide', '(aS)-a-[(4-Morpholinylacetyl)amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-L-phenylalani  namide', 'L-PHENYLALANINAMIDE, (.ALPHA.S)-.ALPHA.-((4-MORPHOLINYLACETYL)AMINO)BENZENEBUTANOYL-L-LEUCYL-N-((1S)-3-METHYL-1-(((2R)-2-METHYLOXIRANYL)CARBONYL)BUTYL)-']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Epz004777","PubChemCID":"56962336","SMILES":"CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC4=C(N=CN=C43)N)O)O","Synonyms":"['EPZ004777', '1338466-77-5', '1-(3-((((2R,3S,4R,5R)-5-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-(tert-butyl)phenyl)urea', 'EPZ 004777', 'CHEMBL2169919', '1-[3-[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea', '7-{5-[(3-{[(4-Tert-Butylphenyl)carbamoyl]amino}propyl)(Propan-2-Yl)amino]-5-Deoxy-Beta-D-Ribofuranosyl}-7h-Pyrrolo[2,3-D]pyrimidin-4-Amine', 'WXRGFPHDRFQODR-ICLZECGLSA-N', '0QK', 'GTPL7377', 'SCHEMBL9274416', 'DTXSID30719178', 'CHEBI:124920', '1-(3-((((2R,3S,4R,5R)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl)methyl)(isopropyl)amino)propyl)-3-(4-tert-butylphenyl)urea', 'EX-A1764', 'BDBM50396023', 'NSC775852', 'NSC780043', 's7353', 'AKOS022185751', 'CCG-269958', 'EPZ004777?', 'NSC 775852', 'NSC-775852', 'NSC-780043', 'NCGC00356803-03', 'NCGC00356803-12', 'AC-27388', 'BE162783', 'HY-15227', 'SW219207-1', 'C72346', 'BRD-K69070623-001-01-1', 'BRD-K69070623-001-02-9', 'BRD-K69070623-003-01-7', 'Q27077205', '1-[3-[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxyoxolan-2-yl]methyl-propan-2-ylamino]propyl]-3-(4-tert-butylphenyl)urea; EPZ 004777', '3-[3-({[(2R,3S,4R,5R)-5-{4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-3,4-dihydroxyoxolan-2-yl]methyl}(propan-2-yl)amino)propyl]-1-(4-tert-butylphenyl)urea', '3-[3-({[(2R,3S,4R,5R)-5-{4-AMINOPYRROLO[2,3-D]PYRIMIDIN-7-YL}-3,4-DIHYDROXYOXOLAN-2-YL]METHYL}(ISOPROPYL)AMINO)PROPYL]-1-(4-TERT-BUTYLPHENYL)UREA', '7-[5-Deoxy-5-[[3-[[[[4-(1,1-Dimethylethyl)phenyl]amino]carbonyl]amino]propyl](1-methylethyl)amino]-?-D-ribofuranosyl]-7H-pyrrolo[2,3  -d]pyrimidin-4-amine']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Exifone","PubChemCID":"40399","SMILES":"C1=CC(=C(C(=C1C(=O)C2=CC(=C(C(=C2)O)O)O)O)O)O","Synonyms":"['EXIFONE', '52479-85-3', \"2,3,3',4,4',5'-Hexahydroxybenzophenone\", 'Adlone', '(2,3,4-Trihydroxyphenyl)(3,4,5-trihydroxyphenyl)methanone', '4-Galloylpyrogallol', 'Exifone [INN]', 'Exifona', '(2,3,4-trihydroxyphenyl)-(3,4,5-trihydroxyphenyl)methanone', 'Methanone, (2,3,4-trihydroxyphenyl)(3,4,5-trihydroxyphenyl)-', 'NSC-680919', '38K9TOD4EG', 'DTXSID9044950', 'NSC680919', '72841-23-7', 'DTXCID7024950', 'Exifonum', 'Exifonum [INN-Latin]', 'Exifona [INN-Spanish]', 'CAS-52479-85-3', 'C13H10O7', 'EINECS 257-945-9', 'UNII-38K9TOD4EG', 'NSC 680919', 'BRN 3401917', 'MFCD00082966', 'EXIFONE [MI]', 'EXIFONE [MART.]', 'EXIFONE [WHO-DD]', '3-08-00-04364 (Beilstein Handbook Reference)', 'SCHEMBL273096', 'CHEMBL329522', 'CHEBI:125609', 'BDBM234394', 'GLXC-23157', 'Tox21_113656', 'Tox21_201450', 'Tox21_303559', 'AKOS015904176', 'CCG-208095', 'FE65021', 'KS-5168', \"2,3,3',4,4'-Hexahydrobenzoxyphenone\", '3,4,5,2,3,4-Hexahydroxybenzophenone', 'NCGC00249050-01', 'NCGC00249050-02', 'NCGC00257438-01', 'NCGC00259001-01', 'DB-019631', \"3,4,5,4',5',6'-hexahydroxy benzophenone\", 'H1065', 'H1783', 'NS00004790', \"2,3,3'',4,4'',5''-Hexahydroxybenzophenone\", \"2,3,3\\\\',4,4\\\\',5\\\\'-Hexahydroxybenzophenone\", 'D91001', 'SR-01000944884', \"2,3,3',4,4',5-HEXAHYDROXY-BENZOPHENONE\", 'SR-01000944884-1', 'BRD-K65716359-001-01-3', 'BRD-K65716359-001-02-1', 'BRD-K65716359-001-04-7', 'Q27216225', \"[2,3,4-trihydroxyphenyl] [3',4',5'-trihydroxyphenyl] methanone\"]","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Tacrolimus","PubChemCID":"445643","SMILES":"C[C@@H]1C[C@@H]([C@@H]2[C@H](C[C@H]([C@@](O2)(C(=O)C(=O)N3CCCC[C@H]3C(=O)O[C@@H]([C@@H]([C@H](CC(=O)[C@@H](/C=C(/C1)\\C)CC=C)O)C)/C(=C/[C@@H]4CC[C@H]([C@@H](C4)OC)O)/C)O)C)OC)OC","Synonyms":"['tacrolimus', '104987-11-3', 'Fujimycin', 'Prograf', 'Tsukubaenolide', 'Tacrolimus anhydrous', 'Protopic', 'Anhydrous Tacrolimus', 'Advagraf', 'Modigraf', 'Prograft', 'Avagraf', 'Envarsus', 'FR-900506', 'Astagraf XL', 'Envarsus XR', 'PROGRAPH', 'TACRO', 'Tacrolimus (anhydrous)', 'Hecoria', '(-)-FK 506', '8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN', 'UNII-Y5L2157C4J', 'CCRIS 7124', 'DTXSID5046354', 'CHEBI:61049', 'HSDB 8195', 'Y5L2157C4J', 'L 679934', 'DTXCID3026354', 'TACROLIMUS (MART.)', 'TACROLIMUS [MART.]', 'NSC-758659', 'UNII-WM0HAQ4WNM', 'TACROLIMUS (USP-RS)', 'CHEBI:61057', 'TACROLIMUS (USP MONOGRAPH)', '8-DEETHYL-8-(BUT-3-ENYL)-ASCOMYCIN', 'NSC 758659', 'TACROLIMUS MONOHYDRATE (EP MONOGRAPH)', 'tacrolimusum', 'NSC717865', 'ENVARSUS-XR', 'D11AH01', 'L04AD02', 'FK506', 'Fk-506', 'Protopy', 'tacrolimus (fk506)', 'LCP-Tacro', 'FK 506', 'Tacrolimus, anhydrous', 'Tacrolimus (INN)', 'FR 900506', 'Prograf (TN)', 'Tacrolimus [USAN]', 'FR900506', 'CHEMBL269732', 'K506', 'NCGC00163470-03', 'TACROLIMUS [INN]', 'FK-506 (Tacrolimus)', 'Graceptor', 'MFCD00869853', '(1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone', 'Advagraf;Fujimycin;FK-506;FR 900506', 'MFCD11045918', 'SR-05000001879', 'Tacrolimus [USAN:INN]', 'Talymus', 'Tacrolimus (Standard)', 'TACROLIMUS [MI]', 'SCHEMBL3088', 'TACROLIMUS [WHO-DD]', 'BSPBio_001279', 'CHEMBL66247', 'L-679934', 'GTPL6784', 'Tacrolimus - Bio-X trade mark', 'Tacrolimus in whole human blood', 'CHEBI:93221', 'HMS503O21', 'HMS1792O21', 'HMS1990O21', 'HMS2093M19', 'HMS3403O21', 'Pharmakon1600-01503968', 'EX-A1677', 'Tox21_112056', 'BDBM50030448', 'BDBM50079777', 'HB0289', 'HY-13756R', 'LMPK04000003', 'NSC758659', 's5003', 'AKOS005145901', 'AC-1182', 'CCG-270494', 'CS-1507', 'DB00864', 'IDI1_001040', 'NCGC00163470-01', 'NCGC00163470-02', 'NCGC00163470-04', 'NCGC00163470-05', 'NCGC00163470-06', 'NCGC00163470-07', 'NCGC00163470-27', '1ST10251', 'BT164430', 'HY-13756', 'SBI-0052894.P002', 'CAS-104987-11-3', 'M2258', 'NS00008708', 'A11860', 'C01375', 'D08556', 'EN300-221601', 'AB01209746-01', 'AB01209746_03', 'Q411648', 'SR-05000001879-1', 'SR-05000001879-2', 'SR-05000001879-5', 'BRD-K35452788-001-02-1', 'BRD-K69608737-001-03-7', 'BRD-K69608737-001-08-6', 'BRD-K69608737-001-10-2', 'Z2242006187', '[(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-', '15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone,', '(1R,9S,12S,13R,14S,17R,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-{1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(prop-2-en-1-yl)-11,28-dioxa-4-azatricyclo[22.3.1.0,4,9]octacos-18-ene-2,3,10,16-tetrone', '(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone', '(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-prop-2-en-1-yl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone', '(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26AS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26A-HEXADECAHYDRO-5,19-DIHYDROXY-3-[(1E)-2-[(1R,3R,4R)-4-HYDROXY-3-METHOXYCYCLOHEXYL]-1-METHYLETHENYL]-14,16-DIMETHOXY-4,10,12,18-TETRAMETHYL-8-(2-PROPEN-1-YL)-15,19', '(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-e', '(E)-(1R,9S,12S,13R,14R,21S,23S,24R,25S,27R)-17-Allyl-1,14-dihydroxy-12-[(E)-2-((3R,4R)-4-hydroxy-3-methoxy-cyclohexyl)-1-methyl-vinyl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-aza-tricyclo[22.3.1.0*4,9*]octacos-18-ene-2,3,10,16-tetraone', '15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-, (3S-(3R*(E(1S*,3S*,4S*)),4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*))-', '15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-', '15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycycl ohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-', '4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-heptadecahydro-5,19-dihydroxy-3-', 'dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,(3S,4R,5S,8R,12S,14S,15R,16S,18R,19R,26aS)-']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Decitabine","PubChemCID":"451668","SMILES":"C1[C@@H]([C@H](O[C@H]1N2C=NC(=NC2=O)N)CO)O","Synonyms":"['Decitabine', \"5-Aza-2'-deoxycytidine\", '2353-33-5', \"2'-Deoxy-5-azacytidine\", '5-Azadeoxycytidine', 'AzadC', '5-Aza-deoxycytidine', '5-AZAdC', '2-deoxyazacytidine', 'Dac', 'Decitabina', '2-Desoxy-5-azacytidine', 'CCRIS 8227', 'DTXSID7030432', 'UNII-776B62CQ27', 'CHEBI:50131', '4-Amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one', 'EINECS 219-089-4', '776B62CQ27', 'BRN 0617982', 'JNJ 30979754', 'JNJ-30979754', 'ASTX-727', 'DTXCID5010432', 'INQOVI COMPONENT DECITABINE', 'ASTX727 COMPONENT DECITABINE', '1,3,5-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-', 'ASTX-727 COMPONENT DECITABINE', 'DECITABINE (MART.)', 'DECITABINE [MART.]', 'AzadC compound', 'Compound, AzadC', 's-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-', '5 Azadeoxycytidine', '5AzadC', \"2' Deoxy 5 azacytidine\", \"5 Aza 2' deoxycytidine\", 'decitabinum', \"2'-desoxy-5-azacytidine\", 'L01BC08', 'DECITABINE COMPONENT OF INQOVI', '219-089-4', 'Dacogen', '5-aza-CdR', '5-aza-dC', 'Dezocitidine', 'NSC 127716', 'MFCD00043011', 'NSC-127716', '4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one', '5A2dc', '5-aza-2-deoxycytidine', '4-amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one', '4-Amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one', '4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one', 'MLS001332587', 'SMR000857076', '4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,3,5-triazin-2-one', '4-amino-1-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one', 'Alpha-Decitibine', 'NSC127716', 'Dacogen (TN)', 'CAS-2353-33-5', \"5-Aza-2'-deoxy Cytidine\", 'NCGC_5ADOC', 'Decitabine (USAN/INN)', 'Decitabine [USAN:INN:BAN]', \"5-Aza-2'-deoxycytidine;NSC 127716\", 'NCGC00166088-01', 'deoxy-5-azacytidine', 'Decitabine (Standard)', 'DECITABINE [MI]', 'DECITABINE [INN]', 'DECITABINE [USAN]', 'DECITABINE [VANDF]', 'MolMap_000063', 'E-7373', 'SCHEMBL4006', 'DECITABINE [WHO-DD]', 'MLS001332588', 'MLS006010136', 'cid_451668', 'Decitabine - Bio-X trade mark', 'GTPL6805', 'CHEMBL1201129', 'DECITABINE [ORANGE BOOK]', 'BDBM96274', 'HY-A0004R', 'EX-A961', 'XAUDJQYHKZQPEU-KVQBGUIXSA-N', 'HMS2235O03', 'HMS3413L07', 'HMS3677L07', '105597-46-4', '22432-95-7', 'BCP02870', 'HY-A0004', \"5-Aza-2'-deoxycytidine, >=97%\", 'Tox21_112311', '4-Amino-1-(2-deoxy-beta-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one', 'HB1356', 's1200', \"5-aza-2'-deoxycytidine (Decitabine)\", 'AKOS015895047', 'Inqovi  (decitabine +  cedazuridine)', 'Tox21_112311_1', 'AC-1135', 'BCP9000593', 'CCG-208143', 'CS-0372', 'DB01262', 'NA02969', '1,3,5-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-.beta.-D-erythro-pentofuranosyl)-', 'ASTX727 (decitabine +  cedazuridine)', 'Decitabine (NSC127716; 5AZA-CdR)', 'NCGC00166088-02', 'NCGC00166088-05', 'AS-17558', 'BA164359', 'BCP0726000271', 'DB-029060', 'SW218076-2', 'D03665', 'EN300-269341', '5-Aza-2 inverted exclamation marka-deoxycytidine', 'AB00918337-07', 'AB00918337_08', 'SR-01000838879', 'Q1181878', 'SR-01000838879-4', 'BRD-K79254416-001-21-8', 'BRD-K79254416-001-22-6', 'Z2467077030', 'decitabine (2 inverted exclamation marka-deoxy-5-azacytidine).cd', '1,3, 5-Triazin-2(1H)-one, 4-amino-1-(2-deoxy--D-erythro-pentofuranosyl)-', '1,3,5-Triazin-2(1H)-one, 4-amino-1-(2-deoxy-|A-D-erythro-pentofuranosyl)-', '4-AMINO-1-(2-DEOXY-.BETA.-D-ERYTHRO-PENTOFURANOSYL)-S-TRIAZIN-2(1H)-ONE', \"4-Amino-1-(2-deoxy-?-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one;5-Aza-2'-deoxy-D-cytidine;2'-Deoxy-5-azacytidine\", \"5-Aza-2'-deoxycytidine; 4-Amino-1-(2-deoxy-b-D-ribofuranosyl)-1,3 ,5-triazin-2(1H)-one; 5-Aza-2'-deoxy-D-cytidine; 2'-Deoxy-5-azacytidin\"]","Type":"small molecule"},{"Action":"not found","PerturbationName":"Unc","PubChemCID":"4369374","SMILES":"C1(=C(NC(=O)NC1=O)[N+](=O)[O-])N","Synonyms":"['5-AMINO 6-NITRO URACIL', '5-AMINO-6-NITROPYRIMIDINE-2,4(1H,3H)-DIONE', 'UNC', '5-amino-6-nitrouracil', 'SCHEMBL4321466', 'DB03099', 'PD007385', 'NS00070233', 'Q27094058']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"PH797804","PubChemCID":"22049997","SMILES":"CC1=C(C=C(C=C1)C(=O)NC)N2C(=CC(=C(C2=O)Br)OCC3=C(C=C(C=C3)F)F)C","Synonyms":"['PH-797804', '586379-66-0', 'PH 797804', '3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide', 'PH797804', '3-[3-bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxopyridin-1-yl]-N,4-dimethylbenzamide', 'PHA-797804', 'CHEBI:82715', 'SI09I1V827', '3-{3-Bromo-4-[(2,4-Difluorobenzyl)oxy]-6-Methyl-2-Oxopyridin-1(2h)-Yl}-N,4-Dimethylbenzamide', 'DTXSID70207342', '3-Bromo-4-((2,4-difluorobenzyl)oxy)-1-(5-((methylamino)carbonyl)-2-methylphenyl)-6-methylpyridin-2(1H)-one', 'Benzamide, 3-(3-bromo-4-((2,4-difluorophenyl)methoxy)-6-methyl-2-oxo-1(2H)-pyridinyl)-N,4-dimethyl-', '3-{3-bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxopyridin-1-yl}-N,4-dimethylbenzamide', '3-(3-bromo-4-((2,4-difluorophenyl)methoxy)-6-methyl-2-oxo-1,2-dihydropyridin-1-yl)-N,4-dimethylbenzamide', '3-(3-bromo-4-((2,4-difluorophenyl)methoxy)-6-methyl-2-oxopyridin-1-yl)-N,4-dimethylbenzamide', '3-{3-bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1,2-dihydropyridin-1-yl}-N,4-dimethylbenzamide', 'DTXCID70129833', '110-020-2', '1358027-80-1', 'GEL7GRJ3R6', 'CHEMBL1088751', '(S)-(-)-PH-797804', '3-(4-(2,4-difluorobenzyloxy)-3-bromo-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide', '3-(3-bromo-4-(2,4-difluorobenzyloxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide', '(3S)-3-(3-Bromo-4-((2,4-difluorophenyl)methoxy)-6-methyl-2-oxo-1(2H)-pyridinyl)-N,4-dimethylbenzamide', '1073667-47-6', 'Benzamide, 3-(3-bromo-4-((2,4-difluorophenyl)methoxy)-6-methyl-2-oxo-1(2H)-pyridinyl)-N,4-dimethyl-, (3S)-', 'UNII-SI09I1V827', '3hll', 'KCAJXIDMCNPGHZ-UHFFFAOYSA-N', 'Kinome_3761', 'UNII-GEL7GRJ3R6', 'MLS006011016', 'rac-PH 797804', 'GTPL7818', 'SCHEMBL2015676', 'BCPP000113', 'HMS3656N17', 'HMS3674G03', 'BCP02266', 'EX-A2344', 'IEC02780', 'BDBM50314073', 'NSC785338', 'NSC800850', 's2726', 'AKOS016007727', 'CCG-264986', 'CS-0465', 'DB07941', 'NSC-785338', 'NSC-800850', 'SB16637', 'SDCCGSBI-0654436.P001', 'NCGC00263165-01', 'NCGC00263165-02', 'DA-66648', 'FP103244', 'HY-10403', 'MS-28852', 'SMR004702814', 'NS00071024', 'PH-797804?', 'SW219277-1', 'E98914', 'PH-797804, (AXIAL S)-(-)-', 'PH-797804, >=98% (HPLC)', '(+/-)-PH 797804', 'PH-797804 (S)-(-)-', 'PH-797804, (-)-', 'BRD-K95880107-001-02-4', 'Q27088355', '(-)3-(4-(2,4-difluorobenzyloxy)-3-bromo-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide', 'I45']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Ps","PubChemCID":"9547096","SMILES":"CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)(O)OC[C@@H](C(=O)O)N)OC(=O)CCCCCCCCCCCCCCCCC","Synonyms":null,"Type":"small molecule"},{"Action":"not found","PerturbationName":"Vu0155056","PubChemCID":"25105704","SMILES":"C1CN(CCC1N2C3=CC=CC=C3NC2=O)CCNC(=O)C4=CC5=CC=CC=C5C=C4","Synonyms":"['1130067-18-3', 'N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-2-naphthamide', 'ML272', 'N-(2-{4-[2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl}ethyl)-2-naphthamide', 'CHEMBL492797', 'N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]naphthalene-2-carboxamide', 'VU0155056', 'N-{2-[4-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)piperidin-1-yl]ethyl}naphthalene-2-carboxamide', 'VU0155056-2', 'N-(2-[4-[2-OXO-2,3-DIHYDRO-1H-BENZO(D)IMIDAZOL-1-YL]PIPERIDIN-1-YL]ETHYL)-2-NAPHTHAMIDE', 'SCHEMBL2724877', 'BDBM87245', 'CHEBI:131157', 'cid_53481919', 'NCGC00386898-01', 'BP-43100', 'VU0155056-1', 'VU0155056-3', 'H20662', 'US9453017, 3', 'VU0156056 (1)', 'Q27224941', 'N-[2-[4-(2-keto-3H-benzimidazol-1-yl)piperidino]ethyl]-2-naphthamide;hydrochloride', 'N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-2-naphthalenecarboxamide', 'N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-2-naphthamide, 56', 'N-(2-{4-[2-oxo-2,3-dihydro-1H-benzo(d)imidazol-1-yl]piperidin-1-yl}ethyl)-2-naphthamide (Inh_VU0155056)', 'N-[2-[4-(2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]naphthalene-2-carboxamide;hydrochloride', 'N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)-1-piperidinyl]ethyl]-2-naphthalenecarboxamide;hydrochloride', 'N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]naphthalene-2-carboxamide;hydrochloride']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Methylstat","PubChemCID":"53392493","SMILES":"COC(=O)/C=C/C(=O)N(CCCCNCC1=CC=C(C=C1)COC(=O)NC2=CC=CC3=CC=CC=C32)O","Synonyms":"['METHYLSTAT', '1310877-95-2', 'methyl (E)-4-[hydroxy-[4-[[4-(naphthalen-1-ylcarbamoyloxymethyl)phenyl]methylamino]butyl]amino]-4-oxobut-2-enoate', '(2E)-4-[Hydroxy[4-[[[4-[[[(1-naphthalenylamino)carbonyl]oxy]methyl]phenyl]methyl]-amino]butyl]amino]-4-oxo-2-butenoic acid methyl ester', 'CHEMBL3347630', 'Methylstat, >=98% (HPLC)', 'SCHEMBL14981874', 'CHEBI:95078', 'DTXSID801025946', 'GLXC-06390', 'KCC87795', 'AKOS030260396', 'NCGC00485261-01', 'DA-65410', 'HY-15221', 'MS-29394', 'CS-0003819', 'JMJD Histone Demethylase Inhibitor IV, Methylstat', 'BRD-K52560704-001-03-8', 'Methyl (E)-4-(hydroxy(4-((4-(((naphthalen-1-ylcarbamoyl)oxy)methyl)benzyl)amino)butyl)amino)-4-oxobut-2-enoate']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"BX912","PubChemCID":"11754511","SMILES":"C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCC4=CN=CN4)Br","Synonyms":"['BX-912', 'BX912', 'BX 912', 'DTXSID30471901', 'N-[3-[[5-bromo-4-[2-(3H-imidazol-4-yl)ethylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide', 'N-(3-((5-bromo-4-(2-(3H-imidazol-4-yl)ethylamino)pyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide', 'DTXCID90422717', '702674-56-4', 'N-[3-[[5-BROMO-4-[[2-(1H-IMIDAZOL-5-YL)ETHYL]AMINO]-2-PYRIMIDINYL]AMINO]PHENYL]-1-PYRROLIDINECARBOXAMIDE', 'N-[3-[[5-bromo-4-[2-(1H-imidazol-5-yl)ethylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide', 'MFCD10565925', 'Y7RG737FY6', 'N-(3-((4-((2-(1H-imidazol-4-yl)ethyl)amino)-5-bromopyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide', 'N-(3-((4-((2-(1H-imidazol-5-yl)ethyl)amino)-5-bromopyrimidin-2-yl)amino)phenyl)pyrrolidine-1-carboxamide', '1-Pyrrolidinecarboxamide, N-(3-((5-bromo-4-((2-(1H-imidazol-4-yl)ethyl)amino)-2-pyrimidinyl)amino)phenyl)-', '1-Pyrrolidinecarboxamide, N-(3-((5-bromo-4-((2-(1H-imidazol-5-yl)ethyl)amino)-2-pyrimidinyl)amino)phenyl)-', 'N-(3-((5-Bromo-4-((2-(1H-imidazol-5-yl)ethyl)amino)-2-pyrimidinyl)amino)phenyl)-1-pyrrolidinecarboxamide', 'N-[3-[[4-[[2-(4-Imidazolyl)ethyl]amino]-5-bromo-2-pyrimidinyl]amino]phenyl]pyrrolidine-1-carboxamide', 'N-{3-[(5-bromo-4-{[2-(1H-imidazol-4-yl)ethyl]amino}pyrimidin-2-yl)amino]phenyl}pyrrolidine-1-carboxamide', 'CID 11754511', 'UNII-Y7RG737FY6', 'MLS006011015', 'GTPL8007', 'SCHEMBL3869633', 'CHEMBL3916849', 'SCHEMBL15825412', 'BDBM17052', 'CHEBI:91357', 'EX-A945', 'BCPP000309', 'GLXC-04876', 'HMS3244G17', 'HMS3244G18', 'HMS3244H17', 'HMS3265I23', 'HMS3265I24', 'HMS3265J23', 'HMS3265J24', 'HMS3654D11', 'HMS3743G13', 'BCP01898', 'BX912?', 'NSC758485', 'AKOS005266650', 'AKOS026750229', 'BCP9000468', 'CCG-269454', 'CS-0079', 'NSC-758485', 'SB19281', 'SDCCGSBI-0645949.P001', 'NCGC00346687-01', 'AC-32073', 'AS-16197', 'HY-11005', 'N-(3-(4-(2-(1H-imidazol-5-yl)ethylamino)-5-bromopyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide', 'SMR004702813', 'SY280412', 'S1275', 'SW220162-1', 'BRD-K49669041-001-01-9', 'BRD-K49669041-001-08-4', 'Q27075611', 'Pyrrolidine-1-carboxylic acid (3-{5-bromo-4-[2-(1H-imidazol-4-yl)-ethylamino]-pyrimidin-2-ylamino}-phenyl)-amide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Edelfosine","PubChemCID":"1392","SMILES":"CCCCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCC[N+](C)(C)C)OC","Synonyms":"['EDELFOSINE', '70641-51-9', 'ET-18-OMe', '1-O-Octadecyl-2-O-methyl-rac-glycero-3-phosphocholine', 'Edelfosine [INN]', 'Edelfosina', 'ET 18-OCH3', 'Ro 14-5243', 'AlP', 'Racemic 1-O-octadecyl-2-O-methylglycero-3-phosphocholine', '1-Octadecyl-2-methylglycero-3-phosphorylcholine', 'rac-1-Octadecyl-2-methoxyglycero-3-phosphocholine', 'NSC-324368', 'NSC-343649', '2-methoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate', '1Y6SNA8L5S', 'CHEMBL28509', '1-O-Octadecyl-2-O-methyl-rac-glyceryl-3-phosphorylcholine', 'DTXSID9045766', 'NIOSH/GA4029000', 'CHEBI:78652', 'NSC324368', '3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, hydroxide, inner salt, 4-oxide, (+-)-', '65492-82-2', 'GA40290000', 'rac-1-Octadecyl-2-methoxy-glycerophosphocholine', 'Choline hydroxide, (+-)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate, inner salt', 'Edelfosinum', 'Edelfosinum [INN-Latin]', 'Edelfosina [INN-Spanish]', 'Choline hydroxide, 2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate, inner salt', '3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide, (+/-)-', '1-Octadecyl-2-methylphosphorylcholine', '1-Octadecyl-2-methylglycero-3-phosphocholine', 'UNII-1Y6SNA8L5S', 'BRN 4358577', 'Choline, 1-octadecyl-2-methoxy-3-phosphoryl-', 'PHOSPHORYLCHOLINE, 1-OCTADECYL-2-METHYL- (ALP)', 'NCGC00093851-01', '3,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, hydroxide, inner salt, 4-oxide', 'MFCD00135190', 'NSC 324368', '2-[hydroxy-(2-methoxy-3-octadecoxy-propoxy)phosphoryl]oxyethyl-trimethyl-ammonium', '(2-methoxy-3-octadecoxypropyl) 2-(trimethylazaniumyl)ethyl phosphate', 'SCHEMBL52069', 'ET-18-O Me', 'Edelfosine, >=95% (HPLC)', 'DTXCID401300168', 'GLXC-25652', '(+/-)-ET-18-OMe', 'CMC_9491', 'Tox21_111225', 'BDBM50011796', 'NSC343649', '(+/-)-ET-18-OCH3', 'HY-108610A', 'NSC 343649', 'Ro-14-5243', '3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide', 'BP-42536', 'FO111151', 'CAS-70641-51-9', 'DB-082060', 'CS-0079514', 'NS00123442', 'Q3579094', '1-octadecyl-2-methoxy-rac-glycero-3-phosphocholine(ET-18-OMe)', '2-Methoxy-3-(octadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate', '2-methoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate', '{2-[Hydroxy-(2-methoxy-3-octadecyloxy-propoxy)-phosphoryloxy]-ethyl}-trimethyl-ammonium', 'Phosphoric acid 2-dimethylamino-ethyl ester 2-methoxy-3-octadecyloxy-propyl ester; ammonium', 'Phosphoric acid 2-trimethylamino-ethyl ester 2-methoxy-3-octadecyloxy-propyl ester', '{2-[Hydroxy-(2-methoxy-3-octadecyloxy-propoxy)-phosphoryloxy]-ethyl}-trimethyl-ammonium(ET-18-OMe)', '3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, inner salt, 4-oxide (9CI)', '3,5,9-Trioxa-4-phosphaheptacosan-1-aminium,4-hydroxy-N,N,N-trimethyl-, hydroxide,inner salt,4-oxide', 'CHOLINE HYDROXIDE, (+/-)-2-METHOXY-3-(OCTADECYLOXY)PROPYL HYDROGEN PHOSPHATE, INNER SALT', 'ethanaminium, 2-[[hydroxy[2-methoxy-3-(octadecyloxy)propoxy]phosphinyl]oxy]-N,N,N-trimethyl-, inner salt']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Dmso","PubChemCID":"679","SMILES":"CS(=O)C","Synonyms":"['dimethyl sulfoxide', 'DMSO', 'Methyl sulfoxide', 'Methylsulfinylmethane', 'Dimethylsulfoxide', 'Methane, sulfinylbis-', 'Demasorb', 'Demsodrox', 'Demavet', 'Domoso', 'Infiltrina', 'Somipront', 'Dolicur', 'Dromisol', 'Durasorb', 'Syntexan', 'Deltan', 'Demeso', 'Hyadur', 'sulfinylbismethane', 'Dimethyl sulfur oxide', 'Doligur', 'Dipirartril-tropico', 'Gamasol 90', 'Sulfinylbis(methane)', 'Dimethylsulfoxyde', 'Dimethylsulphoxide', 'Dimethylsulfoxid', 'Dimetil sulfoxido', 'SQ 9453', 'NSC-763', 'Dimethyli sulfoxidum', 'Dimexidum', '(methylsulfinyl)methane', 'Dimetilsolfossido', '(CH3)2SO', 'DMS-90', 'Sulfoxide, dimethyl', 'A 10846', 'M 176', 'DMS 70', 'DMS 90', 'DMS-70', 'DTXSID2021735', 'SQ-9453', 'NSC763', 'YOW8V9698H', 'CHEBI:28262', '(methanesulfinyl)methane', '(DMSO)', 'DTXCID401735', 'Dimethylsulphinyl', 'DIMETHYL SULFOXIDE (II)', 'DIMETHYL SULFOXIDE [II]', 'DIMETHYL SULFOXIDE (MART.)', 'DIMETHYL SULFOXIDE [MART.]', 'DIMETHYL SULFOXIDE (USP-RS)', 'DIMETHYL SULFOXIDE [USP-RS]', 'DIMETHYL SULFOXIDE (EP MONOGRAPH)', 'DIMETHYL SULFOXIDE [EP MONOGRAPH]', 'DIMETHYL SULFOXIDE (USP MONOGRAPH)', 'DIMETHYL SULFOXIDE [USP MONOGRAPH]', 'Sulphoxide, Dimethyl', 'Domoso Solution', 'Domoso Gel', 'Dimethylis sulfoxidum', 'DIMEHTYLSULFOXYDE', 'G04BX13', 'M02AX03', 'USEPA/OPP Pesticide Code: 000177', '200-664-3', '67-68-5', 'Dimethyl sulphoxide', 'Dimexide', 'Dermasorb', 'Kemsol', 'Rimso-50', 'Topsym', 'Rimso 50', 'Sulfinylbis-methane', 'Caswell No. 381', 'methanesulfinylmethane', 'CCRIS 943', 'NSC 763', 'Methyl sulphoxide', 'dimethyl-sulfoxide', 'S(O)Me2', 'MFCD00002089', 'EPA Pesticide Chemical Code 000177', 'AI3-26477', 'CHEMBL504', \"Methane, 1,1'-sulfinylbis-\", 'Dimethyl sulfoxide, HPLC Grade', 'Dimethyl sulfoxide, 99%', 'Topsym (rescinded)', 'Rimso-5', 'Dimethyl sulfoxide, cryoprotectant vitrification agent', 'Domoso (Veterinary)', 'methylsulfoxide', 'sulfinyldimethane', 'Dimetilsolfossido [DCIT]', 'Dimethyl sulpoxide', 'HSDB 80', 'Dimethylsulfoxyde [INN-French]', 'Dimetil sulfoxido [INN-Spanish]', 'Dimethyli sulfoxidum [INN-Latin]', 'DMSO, sterile filtered', 'EINECS 200-664-3', 'C2H6OS', 'UNII-YOW8V9698H', 'dimethysulfoxide', 'dimethlysulfoxide', 'dimethvlsulfoxide', 'dimethyisulfoxide', 'dimethylsulphoxid', 'dimethy sulfoxide', 'dimetyl sulfoxide', 'dimethyisulphoxide', 'dimethyl sulfoxyde', 'dimethyl-sulfoxyde', 'dimethyl suiphoxide', 'dimethyl-sulphoxide', 'dirnethyl sulfoxide', 'Dimethyl sulfoxixde', 'methylsulfmylmethane', 'DMSO (anydrous)', 'dimethyl sulf oxide', 'Zymso (TN)', 'Dimethyl sulfoxide [USAN:USP:INN:BAN]', 'Methyl sulfoxide (8CI)', 'Rimso-50 (TN)', 'dimethyl sulfoxide (dmso)', 'DMSO (Sterile-filtered)', 'Dimethyl sulfoxide (GMP)', 'EC 200-664-3', 'H3C-SO-CH3', 'BIDD:PXR0182', 'Dimethyl sulfoxide, >=99%', 'Dimethyl sulfoxide, anhydrous', 'METHYL-13C SULFOXIDE', 'Dimethyl sulfoxide, for HPLC', 'Dimethyl sulfoxide (Standard)', 'Methane, sulfinylbis- (9CI)', 'WLN: OS1&1', 'DIMETHYL SULFOXIDE [MI]', 'DIMETHYL SULFOXIDE [INN]', 'DIMETHYL SULFOXIDE [JAN]', 'Dimethyl sulfoxide, >=99.5%', 'Dimethyl sulfoxide, PCR Reagent', 'HY-Y0320C', 'HY-Y0320D', 'HY-Y0320G', 'HY-Y0320R', 'DIMETHYL SULFOXIDE [HSDB]', 'DIMETHYL SULFOXIDE [USAN]', 'Dimethyl sulfoxide,  ACS reagent', 'Methyl sulfoxide, >=99%, FG', 'Dimethyl sulfoxide, p.a., 99%', 'DIMETHYL SULFOXIDE [VANDF]', 'Dimethyl sulfoxide, LR, >=99%', 'Pharmakon1600-01506122', 'CS-B1637', 'Dimethyl sulfoxide (JAN/USP/INN)', 'DIMETHYL SULFOXIDE [WHO-DD]', 'HY-Y0320', 'METHYLSULFINYLMETHANE [FHFI]', 'Tox21_300957', 'BDBM50026472', 'HB3262', 'HB8591', 'NSC760436', 'STL264194', 'Dimethyl sulfoxide, AR, >=99.5%', 'AKOS000121107', 'CCG-213615', 'DB01093', 'DIMETHYL SULFOXIDE [GREEN BOOK]', 'Dimethyl sulfoxide, analytical standard', 'NSC-760436', 'CAS-67-68-5', 'DIMETHYL SULFOXIDE [ORANGE BOOK]', 'Dimethyl sulfoxide pound DMSO pound(c)', 'MRF-0000764', '(methanesulfinyl)methanedimethyl sulfoxide', 'Dimethyl sulfoxide, for molecular biology', 'Dimethyl sulfoxide; AIF; CE0; MS2Dec', 'NCGC00163958-01', 'NCGC00163958-02', 'NCGC00163958-03', 'NCGC00254859-01', '8070-53-9', 'DA-52563', 'Dimethyl sulfoxide, anhydrous, >=99.9%', 'Dimethyl sulfoxide, HPLC grade, 99.9%', 'Dimethyl Sulfoxide [for Spectrophotometry]', 'Dimethyl sulfoxide, for HPLC, >=99.5%', 'Dimethyl sulfoxide, for HPLC, >=99.7%', 'DS-015031', 'CS-1013570', 'D0798', 'D1159', 'D5293', 'Dimethyl sulfoxide solution 50 wt.% in H2O', 'Dimethyl sulfoxide, ACS reagent, >=99.9%', 'Dimethyl sulfoxide, AldraSORB(TM), 99.8%', 'InChI=1/C2H6OS/c1-4(2)3/h1-2H', 'NS00001957', 'EN300-24544', 'D01043', 'Dimethyl sulfoxide, >=99.6%, ReagentPlus(R)', 'Dimethyl sulfoxide, ReagentPlus(R), >=99.5%', 'AB01563146_01', 'Dimethyl Sulfoxide (DMSO), cell culture reagent', 'Dimethyl sulfoxide, p.a., ACS reagent, 99.9%', 'Dimethyl sulfoxide, SAJ first grade, >=99.0%', 'Dimethyl sulfoxide, JIS special grade, >=99.0%', 'Dimethyl sulfoxide, Vetec(TM) reagent grade, 99%', 'Q407927', 'Dimethyl sulfoxide, UV HPLC spectroscopic, 99.9%', 'Dimethyl sulfoxide solution 50 wt.% in distilled H2O', 'Dimethyl sulfoxide, anhydrous, ZerO2(TM), >=99.9%', 'Z199055774', 'Dimethyl sulfoxide, ACS spectrophotometric grade, >=99.9%', 'Dimethyl sulfoxide, puriss. p.a., dried, <=0.02% water', '4H-1,3-oxazine,2-cyclopentyl-5,6-dihydro-4,4,7-trimethyl-', 'Dimethyl sulfoxide, >=99.5% (GC), plant cell culture tested', 'Dimethyl sulfoxide, BioUltra, for molecular biology, >=99.5% (GC)', 'Dimethyl sulfoxide, European Pharmacopoeia (EP) Reference Standard', 'Dimethyl sulfoxide, puriss. p.a., ACS reagent, >=99.9% (GC)', 'Dimethyl sulfoxide, Vetec(TM) reagent grade, anhydrous, >=99.7%', 'Dimethyl sulfoxide, >=99.0%, suitable for absorption spectrum analysis', 'Dimethyl sulfoxide, United States Pharmacopeia (USP) Reference Standard', 'Dimethyl sulfoxide, for inorganic trace analysis, >=99.99995% (metals basis)', 'Dimethyl sulfoxide, meets EP testing specifications, meets USP testing specifications', 'Dimethyl sulfoxide, Hybri-Max(TM), sterile-filtered, BioReagent, suitable for hybridoma, >=99.7%', 'Dimethyl sulfoxide, puriss., absolute, over molecular sieve (H2O <=0.005%), >=99.5% (GC)', 'Dimethyl sulfoxide, sterile-filtered, BioPerformance Certified, meets EP, USP testing specifications, suitable for hybridoma']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"PD153035","PubChemCID":"4705","SMILES":"COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC","Synonyms":"['153436-54-5', 'N-(3-bromophenyl)-6,7-dimethoxyquinazolin-4-amine', 'PD153035', 'PD-153035', 'AG-1517', 'WHI-P-79', 'NSC-669364', 'SU 5271', 'SU-5271', '4-(3-bromophenylamino)-6,7-dimethoxyquinazoline', '(3-Bromophenyl)(6,7-dimethoxyquinazolin-4-yl)amine', 'GI 230329A', '4-QUINAZOLINAMINE, N-(3-BROMOPHENYL)-6,7-DIMETHOXY-', 'CHEBI:91076', 'DTXSID80165328', 'DTXCID5087819', 'pd 153035', '4-(3-BROMOANILINO)-6,7-DIMETHOXYQUINAZOLINE', 'AG 1517', 'TC62B68RSL', 'CHEMBL29197', '4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline', '4-((3-bromophenyl)amino)-6,7-dimethoxyquinazoline', 'Tyrphostin AG 1517', 'ZM 252868', 'UNII-TC62B68RSL', 'SR-01000597835', 'MFCD00934896', 'N-(3-BROMOPHENYL)-6,7-DIMETHOXY-4-QUINAZOLINAMINE', 'Tocris-1037', 'SCHEMBL9423', 'AG-1517 HCl', 'BDBM3032', 'LSPANGZZENHZNJ-UHFFFAOYSA-', 'LSPANGZZENHZNJ-UHFFFAOYSA-N', 'GLXC-05240', 'BCP00569', 'EX-A1235', 'HSCI1_000100', 's6546', 'AKOS003676410', 'BCP9001062', 'CS-0143', 'DS-1673', 'SDCCGSBI-0634834.P002', 'NCGC00024956-01', 'NCGC00024956-02', 'NCGC00024956-04', 'NCGC00024956-18', 'NCGC00024956-19', 'AC-32897', 'HY-14346', 'DB-028592', 'K00043', 'PD 153035(AG-1517)?', 'SR-01000597835-2', 'BRD-K26603252-001-01-9', 'BRD-K26603252-003-04-9', 'Q27163047', 'PD 153035 - CAS 153436-54-5', 'PD153035;SU-5271; AG1517; ZM 252868', 'PD 153035; SU 5271; 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline', 'InChI=1/C16H14BrN3O2/c1-21-14-7-12-13(8-15(14)22-2)18-9-19-16(12)20-11-5-3-4-10(17)6-11/h3-9H,1-2H3,(H,18,19,20)']","Type":"small molecule"},{"Action":"not found","PerturbationName":"(s)-CR8","PubChemCID":"25211051","SMILES":"CC[C@@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=C(C=C3)C4=CC=CC=N4","Synonyms":"['1084893-56-0', 'CR8, (S)-Isomer', '(S)-CR8', '(2S)-2-[[9-propan-2-yl-6-[(4-pyridin-2-ylphenyl)methylamino]purin-2-yl]amino]butan-1-ol', '(2S)-2-[[9-propan-2-yl-6-[[4-(2-pyridinyl)phenyl]methylamino]-2-purinyl]amino]-1-butanol', 'CHEMBL1615221', '(S)-2-((9-Isopropyl-6-((4-(pyridin-2-yl)benzyl)amino)-9H-purin-2-yl)amino)butan-1-ol', '(2s)-2-({9-(1-Methylethyl)-6-[(4-Pyridin-2-Ylbenzyl)amino]-9h-Purin-2-Yl}amino)butan-1-Ol', '3lq5', 'DS28', 'SCHEMBL9927174', 'CHEBI:95340', 'GTPL11064', 'DTXSID60649111', 'HMS3229B15', 'BDBM50466842', 'AKOS025394134', 'AT25365', 'DA-59679', 'HY-112371', 'CS-0045302', 'Q27167221', '(2S)-2-[[9-isopropyl-6-[[4-(2-pyridyl)phenyl]methylamino]purin-2-yl]amino]butan-1-ol', '(2S)-2-{[9-(Propan-2-yl)-6-({[4-(pyridin-2-yl)phenyl]methyl}amino)-9H-purin-2-yl]amino}butan-1-ol', '(2S)-2-{[9-(propan-2-yl)-6-{[4-(pyridin-2-yl)benzyl]amino}-9H-purin-2-yl]amino}butan-1-ol', '(2S)-2-{[9-isopropyl-6-({[4-(pyridin-2-yl)phenyl]methyl}amino)purin-2-yl]amino}butan-1-ol', 'SLQ']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Roscovitine","PubChemCID":"160355","SMILES":"CC[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=CC=C3","Synonyms":"['roscovitine', 'Seliciclib', 'R-Roscovitine', 'Roscovitin', 'CYC 202', 'Seliciclib [INN]', '2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine', 'NSC-701554', 'AL-39256', 'NSC 701554', 'CHEBI:45307', '(2R)-2-[[6-(benzylamino)-9-propan-2-ylpurin-2-yl]amino]butan-1-ol', 'SELICICLIB [MI]', 'SELICICLIB [WHO-DD]', '(2R)-2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol', 'DTXSID20171928', '(2R)-2-{[6-(benzylamino)-9-(1-methylethyl)-9H-purin-2-yl]amino}butan-1-ol', '(2R)-2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-1-butanol', '(R)-2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-1-butanol', '1-Butanol, 2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-, (2R)-', '1-Butanol, 2-((9-(1-methylethyl)-6-((phenylmethyl)amino)-9H-purin-2-yl)amino)-, (R)-', 'seliciclibum', '(2R)-2-((6-(benzylamino)-9-propan-2-ylpurin-2-yl)amino)butan-1-ol', '(2R)-2-((6-(benzylamino)-9-(1-methylethyl)-9H-purin-2-yl)amino)butan-1-ol', '(2R)-2-((6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl)amino)butan-1-ol', '1-Butanol, 2-[[9-(1-methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-, (2R)-', 'DTXCID8094419', '186692-46-6', '(R)-roscovitine', 'CYC202', 'CYC-202', 'Roscovitine (Seliciclib,CYC202)', '(R)-2-((6-(Benzylamino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol', 'Seliciclib (Roscovitine)', 'MFCD02266401', 'CHEMBL14762', '0ES1C2KQ94', 'NSC701554', '(2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]amino]butan-1-ol', '(2R)-2-((6-benzylamino-9-(propan-2-yl)-9h-purin-2-yl)amino)butan-1-ol', 'RRC', 'Rosco', 'UNII-0ES1C2KQ94', '2-(1-ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine', 'BMK1-E12', '1unl', '3ddq', '2a4l', 'BiomolKI_000048', '1-Butanol, (2R)-', 'ROSCOVITINE(Seliciclib)', 'BiomolKI2_000054', 'M02443', 'ROSCOVITINE(Seliciclib)?', 'CBiol_002016', 'Lopac0_001102', 'SCHEMBL94728', 'BSPBio_001078', 'KBioGR_000418', 'KBioSS_000418', 'MLS006011028', 'BDBM7533', 'cid_160355', 'GTPL6035', 'Roscovitine, >=98% (TLC)', 'BCBcMAP01_000013', 'KBio2_000418', 'KBio2_002986', 'KBio2_005554', 'KBio3_000795', 'KBio3_000796', 'EX-A052', 'BCPP000087', 'Bio1_000302', 'Bio1_000791', 'Bio1_001280', 'Bio2_000379', 'Bio2_000859', 'CC205', 'GLXC-04786', 'HMS1362F19', 'HMS1792F19', 'HMS1990F19', 'HMS3229N13', 'HMS3403F19', 'BCP01760', 'Roscovitine (Seliciclib, CYC202)', 'HSCI1_000092', 'NSC800881', '6-(Benzylamino)-2(R)-[[1-(hydroxymethyl)propyl]amino]-9-isopropylpurine', 'AKOS005146319', 'AC-2416', 'CCG-100652', 'DB06195', 'NSC-800881', '2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol', 'IDI1_002134', 'Roscovitine - CAS 186692-46-6', 'SMP1_000266', '2,6,9-Trisubstituted purine deriv. 28', 'NCGC00094374-01', 'NCGC00094374-02', 'NCGC00094374-03', 'NCGC00094374-04', 'NCGC00094374-05', 'NCGC00094374-09', 'NCGC00094374-13', 'NCGC00094374-15', 'AS-56277', 'FR146851', 'HY-30237', 'NCI60_036420', 'SMR004702823', 'NS00068708', 'SW220195-1', 'K00020', 'EN300-26484982', 'Q3494619', 'BRD-K07691486-001-03-1', 'BRD-K07691486-001-05-6', 'BRD-K07691486-001-15-5', 'BRD-K07691486-001-19-7', 'Z1741982636', '(2R)-2-[[6-[(phenylmethyl)amino]-9-propan-2-yl-2-purinyl]amino]-1-butanol', '(2R)-2-[[6-[(phenylmethyl)amino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol', '2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]- 9H-purin-2-yl]amino]-(R)-1-butanol']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Semagacestat","PubChemCID":"9843750","SMILES":"C[C@@H](C(=O)N[C@H]1C2=CC=CC=C2CCN(C1=O)C)NC(=O)[C@H](C(C)C)O","Synonyms":"['Semagacestat', '425386-60-3', 'LY450139', 'Semagacestat (LY450139)', 'LY-450139', 'LY 450139', '866488-53-1', '(S)-2-hydroxy-3-methyl-N-((S)-1-((S)-3-methyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ylamino)-1-oxopropan-2-yl)butanamide', '(2S)-2-hydroxy-3-methyl-N-[(2S)-1-[[(5S)-3-methyl-4-oxo-2,5-dihydro-1H-3-benzazepin-5-yl]amino]-1-oxopropan-2-yl]butanamide', '(S)-2-Hydroxy-3-methyl-N-((S)-1-(((S)-3-methyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-yl)amino)-1-oxopropan-2-yl)butanamide', '3YN0602W4W', 'Butanamide, 2-hydroxy-3-methyl-N-((1S)-1-methyl-2-oxo-2-(((1S)-2,3,4,5-tetrahydro-3- methyl-2-oxo-1H-3-benzazepin-1-yl)amino)ethyl)-, (2S)-', 'Semagacestat [USAN]', 'Semagacestat [USAN:INN]', 'Semagacestat?', 'UNII-3YN0602W4W', 'MFCD09970409', 'SEMAGACESTAT [MI]', 'Semagacestat (USAN/INN)', 'SEMAGACESTAT [INN]', 'Semagacestat; LY450139', 'MLS006010180', 'SCHEMBL417581', 'SEMAGACESTAT [WHO-DD]', 'CHEMBL520733', 'GTPL6978', 'BDBM28944', 'DTXSID10235740', 'CHEBI:131158', 'PKXWXXPNHIWQHW-RCBQFDQVSA-N', 'BCPP000174', 'HMS3884G21', 'EX-A2257', 'NSC755982', 's1594', 'AKOS015924574', 'BCP9000888', 'CCG-268180', 'CS-0292', 'DB12463', 'EX-1762', 'FS34135', 'NSC-755982', 'NCGC00346556-01', 'NCGC00346556-06', 'NCGC00346556-07', '(2S)-2-Hydroxy-3-methyl-N-[(2S)-1-{[(1S)-3-methyl-2-oxo-2,3,4,5-tetrahydro-1H-3-benzazepin-1-yl]amino}-1-oxopropan-2-yl]butanamid', 'AC-24396', 'AS-42018', 'HY-10009', 'SMR004701288', 'NS00069725', 'D09377', 'LY450139, >=98% (HPLC)', 'Q426010', '(2S)-2-HYDROXY-3-METHYL-N-((2S)-1-(((1S)-3-METHYL-2-OXO-2,3,4,5-TETRAHYDRO-1H-3- BENZAZEPIN-1-YL)AMINO)-1-OXOPROPAN-2-YL)BUTANAMIDE', '(2S)-2-hydroxy-3-methyl-N-[(1S)-1-{[(1S)-3-methyl-2-oxo-2,3,4,5-tetrahydro-1H-3-benzazepin-1-yl]carbamoyl}ethyl]butanamide', '(2S)-2-hydroxy-3-methyl-N-[(1S)-1-{[(1S)-3-methyl-2-oxo-4,5-dihydro-1H-3-benzazepin-1-yl]carbamoyl}ethyl]butanamide', '(2S)-2-hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]-butanamide', '(2S)-2-hydroxy-3-methyl-N-[(2S)-1-[[(1S)-3-methyl-2-oxo-4,5-dihydro-1H-3-benzazepin-1-yl]amino]-1-oxopropan-2-yl]butanamide', '(N)-((S)-2-HYDROXY-3-METHYL-BUTYRYL)-1-(L-ALANINYL)-(S)-1-AMINO-3-METHYL-2,3,4,5- TETRAHYDRO-1H-3-BENZAZEPIN-2-ONE', '(N)-((S)-2-Hydroxy-3-methyl-butyryl)-1-(L-alaninyl)-(S)-1-amino-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one', 'BUTANAMIDE, 2-HYDROXY-3-METHYL-N-((1S)-1-METHYL-2-OXO-2-(((1S)-2,3,4,5-TETRAHYDRO-3-METHYL-2-OXO-1H-3-BENZAZEPIN-1-YL)AMINO)ETHYL)-, (2S)-', 'ESF', 'N(SUP 2)-((2S)-2-HYDROXY-3-METHYLBUTANOYL)-N(SUP 1)-((1S)-3-METHYL-2-OXO-2,3,4,5-TETRAHYDRO-1H-3- BENZAZEPIN-1-YL)-L-ALANINAMIDE', 'N2-((2S)-2-(3,5-Difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-laninamide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"CHIR99021","PubChemCID":"9956119","SMILES":"CC1=CN=C(N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N","Synonyms":"['252917-06-9', 'CHIR-99021', 'laduviglusib', 'CHIR 99021', 'CT99021', 'CT-99021', '6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile', 'CHIR-911', 'CT 99021', 'Laduviglusib [USAN]', 'CHR00921', '6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile', '234CMT4GK4', 'CHIR 911', 'CHR-00921', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile', 'LADUVIGLUSIB [INN]', 'CHEBI:91091', 'DTXSID90179931', '3-Pyridinecarbonitrile, 6-((2-((4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl)amino)ethyl)amino)-', 'Laduviglusib (USAN)', '6-[(2-{[4-[2,4-Dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]NH}ethyl)NH]pyridine-3-CN', '6-((2-((4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)pyridine-3-carbonitrile', '6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl)NH)ethyl)NH)pyridine-3-CN', '6-(2-((4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethylamino)pyridine-3-carbonitrile', 'DTXCID50102422', '809-015-4', 'CHIR99021', '6-[2-[4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino]ethylamino]pyridine-3-carbonitrile', 'Laduviglusib (GMP)', 'FX03', '6-((2-((4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile', 'CHIR-99021 (CT99021)', 'CHEMBL412142', '[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile', '252917-06-9 (free base)', 'CHIR 99021 Hydrochloride Salt', 'GSK-3 Inhibitor XVI', '6-(2-(4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino)ethylamino)nicotinonitrile', 'UNII-234CMT4GK4', '6-[(2-([4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino)ethyl)amino]pyridine-3-carbonitrile', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile', '65C', 'MFCD11846251', 'Kinome_3785', 'Laduviglusib (Standard)', 'SCHEMBL151139', 'GTPL8014', 'EX-A535', 'BCPP000285', 'HMS3295O15', 'BCP01901', 'BDBM50325983', 'HB1261', 'HY-10182G', 'HY-10182R', 's1263', 'WHO 11473', 'AKOS015904410', 'AKOS026750421', 'BCP9000520', 'CCG-269402', 'CS-0181', 'FD43329', 'SB19266', 'SDCCGSBI-0654265.P001', 'CHIR-99021,CT99021', 'NCGC00250379-01', 'NCGC00250379-03', 'NCGC00250379-09', 'NCGC00250379-21', '6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile', '6-[2-[[4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile', 'AC-25532', 'AS-16523', 'HY-10182', 'SY016322', 'C2943', 'CHIR99021, >=98% (HPLC)', 'CS-0615620', 'CHIR-99021 (CT99021)?', 'D12196', 'EN300-18520201', 'GSK-3 Inhibitor XVI - CAS 252917-06-9', 'BRD-K16189898-001-02-9', 'BRD-K16189898-001-04-5', 'BRD-K16189898-001-09-4', 'BRD-K16189898-001-10-2', 'BRD-K16189898-001-11-0', 'BRD-K16189898-001-15-1', 'BRD-K16189898-003-03-3', 'Q27075965', '6-[(2-{[4-(2,4-dichlorophenyl) -5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol -2-yl)-pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)-pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino }ethyl)amino]pyridine-3-carbonitrile', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3 -carbonitrile', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile', '6-[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-2-imidazolyl)-2-pyrimidinyl]amino]ethylamino]-3-pyridinecarbonitrile', '6-{2-[4-(2,4-dichloro-phenyl)-5-(4-methyl-1h-imidazol-2-yl)-pyrimidin-2-ylamino]-ethylamino}-nicotinonitrile', '6-{2-[4-(2,4-dichloro-phenyl)-5-(5-methyl-1h-imidazol-2-yl)-pyrimidin-2-ylamino]-ethylamino}-nicotinonitrile']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Unc1215","PubChemCID":"57339144","SMILES":"C1CCN(C1)C2CCN(CC2)C(=O)C3=CC(=C(C=C3)C(=O)N4CCC(CC4)N5CCCC5)NC6=CC=CC=C6","Synonyms":"['UNC1215', '1415800-43-9', '(2-(phenylamino)-1,4-phenylene)bis((4-(pyrrolidin-1-yl)piperidin-1-yl)methanone)', 'UNC-1215', 'UNC 1215', \"Methanone, 1,1'-[2-(phenylamino)-1,4-phenylene]bis[1-[4-(1-pyrrolidinyl)-1-piperidinyl]-\", 'CHEMBL2426364', '[3-anilino-4-(4-pyrrolidin-1-ylpiperidine-1-carbonyl)phenyl]-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone', 'N-Phenyl-2,5-bis({[4-(pyrrolidin-1-yl)piperidin-1-yl]carbonyl})aniline', '2-Phenylamino-1,4-bis(4-(pyrrolidinyl)piperidinyl)benzamide', 'N-phenyl-2,5-bis[4-(pyrrolidin-1-yl)piperidine-1-carbonyl]aniline', '[2-(Phenylamino)benzene-1,4-Diyl]bis{[4-(Pyrrolidin-1-Yl)piperidin-1-Yl]methanone}', 'C32H43N5O2', 'MFCD22683289', 'MLS006011024', 'GTPL8232', 'SCHEMBL19730381', 'CHEBI:95086', 'EX-A193', 'DTXSID301026044', 'GLXC-03111', 'HMS3426E15', 'HMS3652P22', 'HMS3744C05', '2-Phenylamino-1,4-bis[4-(pyrrolidinyl)-piperidinyl)benzamide]', 'BCP07393', 'BDBM50440614', 's7088', 'UNC-1215?', 'AKOS024458279', 'CCG-269911', 'CS-1646', 'SB19337', 'NCGC00344623-02', 'NCGC00344623-12', 'AC-32715', 'AS-16797', 'BP-21087', 'DA-45154', 'HY-15649', 'SMR004702819', 'UNC1215, >=98% (HPLC)', 'SW220042-1', 'BRD-K83189926-001-03-1', 'BRD-K83189926-001-04-9', 'Q27089089', '(2-?(phenylamino)-?1,?4-?phenylene)bis((4-?(pyrrolidin-?1-?yl)piperidin-?1-?yl)methanone)']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"LY2090314","PubChemCID":"10029385","SMILES":"C1CCN(CC1)C(=O)N2CCN3C=C(C4=CC(=CC(=C43)C2)F)C5=C(C(=O)NC5=O)C6=CN=C7N6C=CC=C7","Synonyms":"['LY2090314', 'LY-2090314', '3-(9-Fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]indol-7-yl)-4-(imidazo[1,2-a]pyridin-3-yl)-1H-pyrrole-2,5-dione', 'UNII-822M3GYM67', 'CHEBI:167661', 'DTXSID90209085', '1H-PYRROLE-2,5-DIONE, 3-(9-FLUORO-1,2,3,4-TETRAHYDRO-2-(1-PIPERIDINYLCARBONYL)PYRROLO(3,2,1-JK)(1,4)BENZODIAZEPIN-7-YL)-4-IMIDAZO(1,2-A)PYRIDIN-3-YL-', '3-[9-fluoro-1,2,3,4-tetrahydro-2-(1-piperidinylcarbonyl)pyrrolo[3,2,1-jk][1,4]benzodiazepin-7-yl]-4-imidazo[1,2-a]pyridin-3-yl-1H-pyrrole-2,5-dione', '3-[9-fluoro-2-(piperidin-1-ylcarbonyl)-1,2,3,4-tetrahydro[1,4]diazepino[6,7,1-hi]indol-7-yl]-4-(imidazo[1,2-a]pyridin-3-yl)-1H-pyrrole-2,5-dione', 'PYRROLO(3,2,1-JK)(1,4)BENZODIAZEPINE, 7-(2,5-DIHYDRO-4-IMIDAZO(1,2-A)PYRIDIN-3-YL-2,5-DIOXO-1H-PYRROL-3-YL)-9-FLUORO-1,2,3,4-TETRAHYDRO-2-(1-PIPERIDINYLCARBONYL)-', '3-(6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo(6.4.1.0^(4,13))trideca-2,4,6,8(13)-tetraen-3-yl)-4-(imidazo(1,2-a)pyridin-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione', '3-(9-fluoro-1,2,3,4-tetrahydro-2-(1-piperidinylcarbonyl)pyrrolo(3,2,1-jk)(1,4)benzodiazepin-7-yl)-4-imidazo(1,2-a)pyridin-3-yl-1H-pyrrole-2,5-dione', '3-(9-fluoro-2-(piperidin-1-ylcarbonyl)-1,2,3,4-tetrahydro(1,4)diazepino(6,7,1-hi)indol-7-yl)-4-(imidazo(1,2-a)pyridin-3-yl)-1H-pyrrole-2,5-dione', '3-(9-Fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetrahydro-(1,4)diazepino(6,7,1-hi)indol-7-yl)-4-(imidazo(1,2-a)pyridin-3-yl)-1H-pyrrole-2,5-dione', '3-[6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.0^{4,13}]trideca-2,4,6,8(13)-tetraen-3-yl]-4-{imidazo[1,2-a]pyridin-3-yl}-2,5-dihydro-1H-pyrrole-2,5-dione', 'DTXCID10131576', 'GSK-3 Inhibitor LY2090314', '603288-22-8', 'LY 2090314', 'Kinome_3681', 'CHEMBL362558', '822M3GYM67', '3-[6-Fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl]-4-imidazo[1,2-a]pyridin-3-ylpyrrole-2,5-dione', 'MFCD20526532', 'SCHEMBL633455', 'GTPL7958', 'GLXC-06318', 'HMS3673E17', 'HMS3747E07', 'BCP07855', 'EX-A2214', 'BDBM50150699', 'NSC772198', 'NSC801005', 's7063', 'AKOS026750195', 'AKOS032950045', 'CCG-269790', 'CS-1633', 'DB11913', 'NSC-772198', 'NSC-801005', 'SB16558', 'LY 2090314 [WHO-DD]', 'NCGC00378942-02', 'NCGC00378942-05', 'AC-32724', 'AS-56097', 'DA-55098', 'FL104294', 'HY-16294', 'LY2090314?', 'NS00069302', 'LY2090314, >=98% (HPLC)', 'BRD-K78055238-001-01-8', 'Q27082598', '3-(9-Fluoro-2-(piperidin-1-ylcarbonyl)-1,2,3,4-tetrahydro(1,4)diazepino(6,7,1-hi)indol-7-yl)-4-imidazo(1,2-a)pyridin-3-yl-1H-pyrrole-2,5-dione', '3-(9-fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]indol-7-yl)-4-(H-imidazo[1,2-a]pyridin-3-yl)-1H-pyrrole-2,5-dione', '3-[6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.0?,(1)(3)]trideca-2,4,6,8(13)-tetraen-3-yl]-4-{imidazo[1,2-a]pyridin-3-yl}-1H-pyrrole-2,5-dione', '3-[9-Fluoro-2-(piperidine-1-carbonyl)-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]indol-7-yl]-4-imidazo[1,2-a]pyridin-3-yl-pyrrole-2,5-dione']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Trichostatin a","PubChemCID":"444732","SMILES":"C[C@H](/C=C(\\C)/C=C/C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C","Synonyms":"['trichostatin A', '58880-19-6', 'CHEBI:46024', 'DTXSID6037063', '3X2S926L3Z', 'TRICHOSTATIN A [MI]', '2,4-Heptadienamide, 7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-', '7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide', 'VTR-297', 'NSC 311042', 'NSC-311042', '(2E,4E,6R)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide', '2,4-Heptadienamide, 7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-, (2E,4E,6R)-', 'TSA antibioitc', '7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE', '2,4-HEPTADIENAMIDE, 7-(4-(DIMETHYLAMINO)PHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-,(2E,4E,6R)-', '2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-, (2E,4E,6R)-', 'NSC311042', '(2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide', 'DTXCID4017063', '(2E,4E)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide', '(2E,4E)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide', '611-758-2', 'TSA', 'Trichostatin', 'Trichostatin A (TSA)', '(2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide', 'Antibiotic A-300', '(R)-Trichostatin A', '(R,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide', 'MFCD03848392', 'GNF-PF-1011', '58880-19-6 (R-isomer)', '2,4-Heptadienamide,7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-, (2E,4E,6R)-', 'A-300-I', '[R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide', 'Trichostatin-A', 'Tricostatin A', 'TSN', 'Trichostatina', 'trichostatine a', 'UNII-3X2S926L3Z', 'Trichlostatin A', 'Trichostatin(s)', '(2E,4E,6R)-7-(4-dimethylaminophenyl)-4,6-dimethyl-7-oxo-hepta-2,4-dienehydroxamic acid', '(2E,4E,6R)-7-(4-Dimethylaminophenyl)-N-hydroxy-4,6-dimethyl-7-oxo-hepta-2,4-dienamide', '(2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-, 2,4-heptadienamide; [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide; (R)-Trichostatin A; TSA;', 'Trichostatin A,TSA', 'NCGC_TSA', '1c3r', '3f0r', 'Trichostatin A (TSA)?', 'SCHEMBL19886', 'MLS006011095', 'SGCTO-002', 'SCHEMBL675951', 'GTPL7005', 'VTR297', 'CHEBI:93196', 'BCPP000035', 'GLXC-05604', 'HMS1362L09', 'HMS1792L09', 'HMS1990L09', 'HMS3403L09', 'HMS3649O20', 'BCP01776', 'EX-A1665', 'BDBM50005711', 'HB1402', 'LMPK01000055', 's1045', 'Trichostatin A from Streptomyces sp.', 'AKOS015899840', 'CCG-208142', 'CCG-208681', 'CS-0499', 'DB04297', 'NCGC00162453-01', 'NCGC00162453-02', 'NCGC00162453-03', 'NCGC00162453-04', 'NCGC00162453-05', 'NCGC00162453-15', '3C10', 'AC-35470', 'AS-74315', 'HY-15144', 'PD119680', 'SMR004702883', 'NS00034030', 'SW219664-1', 'T2477', 'M02571', 'Q425894', 'SR-05000013796', 'SR-05000013796-3', 'BRD-K68202742-001-04-1', 'BRD-K68202742-001-05-8', 'BRD-K68202742-001-13-2', 'BRD-K68202742-001-16-5', 'Trichostatin A, >=98% (HPLC), from Streptomyces sp.', 'Trichostatin A, Streptomyces sp. - CAS 58880-19-6', 'Trichostatin A??, Vetec(TM) reagent grade, from Streptomyces sp., >=98%', '7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6R-dimethyl-7-oxo-2E,4E-heptadienamide', '2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-, (2E,4E,6R)- (9CI)', '2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-, [R-(E,E)]-']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Gsk126","PubChemCID":"68210102","SMILES":"CC[C@H](C)N1C=C(C2=C(C=C(C=C21)C3=CN=C(C=C3)N4CCNCC4)C(=O)NCC5=C(C=C(NC5=O)C)C)C","Synonyms":"['GSK126', '1346574-57-9', 'GSK-126', 'GSK 126', '(S)-1-(sec-Butyl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide', 'GSK2816126', 'GSK-2816126', 'W4OGW9QZ97', '1-[(2S)-butan-2-yl]-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-methyl-6-(6-piperazin-1-ylpyridin-3-yl)indole-4-carboxamide', 'CHEMBL3287735', 'EZH2 inhibitor', 'GSK-2816126A', '1H-Indole-4-carboxamide, N-((1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl)-3-methyl-1-((1S)-1-methylpropyl)-6-(6-(1-piperazinyl)-3-pyridinyl)-', 'S)-1-(sec-butyl)-N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide', '1-[(2S)-butan-2-yl]-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-3-methyl-6-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indole-4-carboxamide', 'N-((1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl)-3-methyl-1-((1S)-1-methylpropyl)-6-(6-(1-piperazinyl)-3-pyridinyl)-1H-indole-4-carboxamide', 'FKSFKBQGSFSOSM-QFIPXVFZSA-N', 'C31H38N6O2', '1-[(2S)-BUTAN-2-YL]-N-[(4,6-DIMETHYL-2-OXO-1H-PYRIDIN-3-YL)METHYL]-3-METHYL-6-[6-(PIPERAZIN-1-YL)PYRIDIN-3-YL]INDOLE-4-CARBOXAMIDE', 'A9G', 'GSK126 HCl', 'UNII-W4OGW9QZ97', 'GSK-126 HCl', 'MLS006010251', 'GTPL7012', 'SCHEMBL12180401', 'EX-A499', 'CHEBI:124921', 'DTXSID301025739', 'BCP06129', 'GSK-126?', 'BDBM50017293', 'NSC780041', 'NSC789702', 's7061', 'AKOS027322309', 'CCG-269895', 'CS-1401', 'FB43076', 'GSK 2816126 [WHO-DD]', 'NSC-780041', 'NSC-789702', 'NCGC00347286-01', 'AS-16379', 'HY-13470', 'N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-3-methyl-1-[(1S)-1-methylpropyl]-6-[6-(1-piperazinyl)-3-pyridinyl]-1H-indole-4-carboxamide', 'SMR004701327', 'BRD-K21867462-001-02-9', 'BRD-K21867462-001-03-7', 'Q27077865', '(S)-1-sec-butyl-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide', 'S)-1-(sec-butyl)-N-((4,6-Dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carb  oxamide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"GSK2334470","PubChemCID":"46215815","SMILES":"C[C@@H]1CC[C@@H](CN1C2=NC(=NC(=C2)C3=CC4=C(C=C3)C(=NN4)N)NC)C(=O)NC5CCCCC5","Synonyms":"['GSK2334470', '1227911-45-6', 'GSK 2334470', 'GSK-2334470', 'QB5BF4GJ87', '(3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-3-piperidinecarboxamide', '(3S,6R)-1-(6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl)-N-cyclohexyl-6-methyl-3-piperidinecarboxamide', '3-Piperidinecarboxamide, 1-(6-(3-amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl)-N-cyclohexyl-6-methyl-, (3S,6R)-', '3-Piperidinecarboxamide, 1-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-, (3S,6R)-', '(3S,6R)-1-(6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl)-N-cyclohexyl-6-methylpiperidine-3-carboxamide', '(3S,6R)-1-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl]-N-cyclohexyl-6-methylpiperidine-3-carboxamide', 'CHEMBL1765740', 'QLPHOXTXAKOFMU-WBVHZDCISA-N', 'UNII-QB5BF4GJ87', 'MLS006011255', 'GTPL8008', 'SCHEMBL1317022', 'PDK1 inhibitor GS2334470', 'CHEBI:91465', 'DTXSID40673111', 'GLXC-05931', 'EX-A1544', 'BDBM50341243', 'NSC759658', 's7087', 'AKOS024458000', 'CCG-269373', 'CS-0917', 'NSC-759658', 'GSK2334470?', 'AC-32824', 'AS-16973', 'FG172878', 'HY-14981', 'SMR004703010', 'SK2334470', 'SW219485-1', 'C71892', 'GSK2334470, >=98% (HPLC)', 'BRD-K70642949-001-01-1', 'Q27077885']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"MK2206","PubChemCID":"24964624","SMILES":"C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N","Synonyms":"['MK-2206', '1032349-93-1', '8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one', 'MK2206', 'MK 2206', 'MK-2206 free base', '51HZG6MP1K', 'DTXSID3048948', 'CHEBI:67271', 'DTXCID0028874', '1032349-77-1', '1,2,4-Triazolo(3,4-f)(1,6)naphthyridin-3(2H)-one, 8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-', '8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one', '8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one', '8-(4-(1-AMINOCYCLOBUTYL)PHENYL)-9-PHENYL-1,2,4-TRIAZOLO(3,4-F)(1,6)NAPHTHYRIDIN-3(2H)-ONE', 'MK-2206 [WHO-DD]', '8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl(1,2,4)triazolo(3,4-f)(1,6)naphthyridin-3(2H)-one', '8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-2H-(1,2,4)triazolo(3,4-f)(1,6)naphthyridin-3-one', '8-(4-(1-AMINOCYCLOBUTYL)PHENYL)-9-PHENYL-1,2,4-TRIAZOLO(3,4-F)(1,6)NAPHTHYRIDIN-3(2H)-ONE HYDROCHLORIDE (1:1)', 'Akt Inhibitor MK2206', 'MK-2206 (free base)', 'CHEMBL1079175', 'NCGC00186465-01', '8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one', 'UNII-51HZG6MP1K', '1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-;1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-;8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-ol', '8-(4-(1-Aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthy ridin-3(2H)-one', 'CAS-1032350-13-2', 'SCHEMBL530721', 'MK2206 2HCl', 'GTPL7945', 'MK-2206 2HCl?', 'ULDXWLCXEDXJGE-UHFFFAOYSA-N', 'BCP20200', 'Tox21_113368', 'BDBM50313650', 'NSC756656', 'NSC800794', 'NSC839864', 'AKOS032945686', 'Tox21_113368_1', 'BCP9000938', 'MK 2206;MK2206', 'NSC-756656', 'NSC-800794', 'NSC-839864', 'SB16805', 'SDCCGSBI-0654336.P001', 'NCGC00186465-02', 'NCGC00186465-03', 'NCGC00186465-04', 'NCGC00186465-08', 'HY-10357', 'DB-058959', 'CS-0002565', 'F86411', 'MK2206;MK 2206;MK-2206 dihydrochloride', 'cas:1032350-13-2;MK 2206', 'BRD-K68065987-300-02-6', 'BRD-K68065987-300-09-1', 'Q25100065', '8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl[1,2,4]triazolo[3,4-f]-1,6-naphthyridin-3(2H)-one']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"U73122","PubChemCID":"104794","SMILES":"C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2NCCCCCCN4C(=O)C=CC4=O)CCC5=C3C=CC(=C5)OC","Synonyms":"['1-[6-[[(17beta)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione', '1-[6-[((17beta)-3-Methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-1H-pyrrole-2,5-dione', '1-(6-(((17beta)-3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione', '112648-68-7', 'U-73122', 'U73122', 'U 73122', '1-(6-((3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione', 'U-73,122', 'U-73122 hydrate', '1-[6-[[(8R,9S,13S,14S,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]amino]hexyl]pyrrole-2,5-dione', 'CHEMBL1256678', 'CHEBI:90690', '1-(6-(((8R,9S,13S,14S,17S)-3-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione', 'MolMap_000051', '1-(6-((17-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione', 'LUFAORPFSVMJIW-ZRJUGLEFSA-N', '1-(6-{[(1S,3AS,3BR,9BS,11AS)-7-METHOXY-11A-METHYL-1H,2H,3H,3AH,3BH,4H,5H,9BH,10H,11H-CYCLOPENTA[A]PHENANTHREN-1-YL]AMINO}HEXYL)PYRROLE-2,5-DIONE', 'MFCD00893825', '1H-Pyrrole-2,5-dione, 1-(6-(((17beta)-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-', 'BSPBio_001222', 'SCHEMBL676619', 'GTPL5283', 'DTXSID3036739', 'EX-A677', 'Bio1_000364', 'Bio1_000853', 'Bio1_001342', 'GLXC-05925', 'HMS3403N03', 'HMS3649C14', '1-[6-[[(13S,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]amino]hexyl]pyrrole-2,5-dione', 'BDBM50446424', 'MFCD12910450', 's8011', 'AKOS024456502', 'NCGC00025091-03', 'NCGC00179254-01', 'AC-32913', 'AS-73949', 'FU158665', 'HY-13419', 'SR-01000597394', 'SR-01000946598', 'U73122?', 'SR-01000597394-1', 'SR-01000946598-1', 'Q27089044', 'U-73122 - CAS 112648-68-7', '1-(6-{[(17beta)-3-methoxyestra-1(10),2,4-trien-17-yl]amino}hexyl)-1H-pyrrole-2,5-dione', '1-[6-[[(17|A)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1H-pyrrole-2,5-dione', '1-[6-[[(17b)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-1h-pyrrole-2,5-dione', '1-(6-{[(1S,10R,11S,14S,15S)-5-methoxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-trien-14-yl]amino}hexyl)-2,5-dihydro-1H-pyrrole-2,5-dione', '1-(6-{[(1S,3aS,3bR,9bS,11aS)-7-methoxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]amino}hexyl)-2,5-dihydro-1H-pyrrole-2,5-dione', '1-[6-((8R,9S,13S,14S,17S)-3-Methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ylamino)-hexyl]-pyrrole-2,5-dione']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Ex527","PubChemCID":"5113032","SMILES":"C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N","Synonyms":"['49843-98-3', 'Selisistat', '6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide', 'EX 527', 'SEN0014196', 'EX527', 'Selisistat [INN]', 'CHEBI:90369', 'L19ECD5014', 'rac-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide', 'SELISISTAT [WHO-DD]', 'DTXSID10964442', 'EX527 cpd', 'DTXCID101392140', '664-029-6', 'EX-527', 'SIRT1 Inhibitor III', 'EX 527 (Selisistat)', 'Selisistat (EX 527)', 'CHEMBL420311', 'UNII-L19ECD5014', 'MFCD03009471', 'SEN-0014196', '1H-Carbazole-1-carboxamide, 6-chloro-2,3,4,9-tetrahydro-', 'EX-527(Selisistat)?', 'Cambridge id 6859180', 'Oprea1_353257', 'Oprea1_367943', 'MLS006011757', 'GTPL8100', 'SCHEMBL1275557', 'EX-527 (SELISISTAT)', 'FUZYTVDVLBBXDL-UHFFFAOYSA-N', 'GLXC-04708', 'HMS3426E09', 'HMS3654P22', 'HMS3743I17', 'HMS3747M05', 'HMS3884K19', 'BCP02889', 'EX-A1064', 'BDBM50178769', 's1541', 'STK522511', 'AKOS002364303', 'AKOS016347570', 'AB88646', 'AB89313', 'BCP9000673', 'CCG-208710', 'CS-0960', 'DB13978', 'FC34132', 'SB16664', 'EX 527,SEN0014196', 'NCGC00242458-01', 'AC-32746', 'HY-15452', 'SMR004703473', 'BCP0726000108', 'DB-082965', 'EX-527, >=98% (HPLC)', 'C2739', 'SW218147-2', 'AB00121519-01', 'AH-262/08804001', 'SR-01000501008', 'SR-01000501008-1', 'BRD-A73908300-001-04-2', 'BRD-A73908300-001-06-7', 'BRD-A73908300-001-09-1', 'Q27088776', '(+/-)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide', '6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid, amide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Dactolisib","PubChemCID":"11977753","SMILES":"CC(C)(C#N)C1=CC=C(C=C1)N2C3=C4C=C(C=CC4=NC=C3N(C2=O)C)C5=CC6=CC=CC=C6N=C5","Synonyms":"['dactolisib', '915019-65-7', 'NVP-BEZ235', 'BEZ235', 'NVP-BEZ 235', 'BEZ-235', '2-methyl-2-(4-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl)propanenitrile', 'NVPBEZ235', 'BEZ 235', 'NVP-BEZ-235', 'NVP BEZ235', 'Dactolisib [USAN]', 'RTB101', 'RTB-101', 'Dactolisib [USAN:INN]', 'RUJ6Z9Y0DT', 'NSC-751249', 'CHEBI:71952', 'DACTOLISIB [INN]', 'DACTOLISIB [WHO-DD]', '2-methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-ylimidazo[4,5-c]quinolin-1-yl)phenyl]propanenitrile', 'DTXSID10238599', 'NSC 751249', '2-methyl-2-(4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-1h-imidazo(4,5-c)quinolin-1-yl)phenyl)propanenitrile', '2-methyl-2-{4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl]phenyl}propanenitrile', '2-methyl-2-(4-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo(4,5-c)quinolin-1-yl)phenyl)propanenitrile', 'Benzeneacetonitrile, 4-(2,3-dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo(4,5-c)quinolin-1-yl)-alpha,alpha-dimethyl-', 'dactolisibum', '2-methyl-2-(4-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-1H-imidazo(4,5-c)quinolin-1-yl)phenyl)propanenitrile', '2-methyl-2-(4-(3-methyl-2-oxo-8-quinolin-3-ylimidazo(4,5-c)quinolin-1-yl)phenyl)propanenitrile', '2-Methyl-2-(4-{3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl}phenyl)propanenitrile', 'DTXCID10161090', 'BEZ235 (NVP-BEZ235, Dactolisib)', '915019-65-7 (free base)', '2-Methyl-2-[4-(3-methyl-2-oxo-8-quinolin-3-yl-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)-phenyl]-propionitrile', 'S1009', 'BEZ235 (NVP-BEZ235)', '2-Methyl-2-[4-[3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile.', 'UNII-RUJ6Z9Y0DT', 'MFCD10565944', 'Kinome_2911', 'CT-BEZ', 'Dactolisib (BEZ235)', 'Dactolisib; BEZ-235', 'Dactolisib (USAN/INN)', 'Nvp-bez235, free base', 'mTOR Inhibitor, BEZ235', 'NVP BEZ 235', 'NVP-BEZ235?', 'SCHEMBL143623', 'GTPL7950', 'CHEMBL1879463', 'BDBM92862', 'EX-A404', 'BCPP000344', 'HMS3244G21', 'HMS3244G22', 'HMS3244H21', 'HMS3672E19', 'BCP00216', 'IVB20674', 'NSC751249', 'NSC755807', 'NSC800085', 'AKOS005217097', 'BCP9000397', 'CCG-207981', 'CS-0080', 'DB11651', 'ES-0038', 'FD26487', 'NSC-755807', 'NSC-800085', 'PB26555', 'SDCCGSBI-0646961.P003', 'Dactolisib (BEZ235, NVP-BEZ235)', 'NCGC00187481-01', 'NCGC00187481-02', 'NCGC00187481-04', 'NCGC00187481-05', 'NCGC00187481-06', 'NCGC00187481-11', 'NCGC00187481-15', '2-(4-(2,3-dihydro-3-methyl-2-oxo-8-(quinolin-3-yl)imidazo[4,5-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile', 'AC-25486', 'HY-50673', 'NS00071714', 'EN300-60135', 'D10552', 'Q4835503', 'BRD-K12184916-001-01-4', 'BRD-K12184916-001-15-4', 'BRD-K12184916-001-19-6', 'Z329731510', '1028385-31-0', '2-Methyl-2-(4-(3-methyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydro-imidazo[4,5-c]quinolin-1-yl)phenyl)propionitrile', '2-methyl-2-[4-[3-methyl-2-oxo-8-(3-quinolyl)imidazo[4,5-c]quinolin-1-yl]phenyl]propanenitrile', '2-METHYL-2-{4-[3-METHYL-2-OXO-8-(QUINOLIN-3-YL)-1H,2H,3H-IMIDAZO[4,5-C]QUINOLIN-1-YL]PHENYL}PROPANENITRILE', '4-[2,3-Dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4, 5-c]quinolin-1-yl]-.alpha.,.alpha.-dimethylbenzeneacetonitrile', '4-[2,3-Dihydro-3-methyl-2-oxo-8-(3-quinolinyl)-1H-imidazo[4,5-c]quinolin-1-yl]-?,?-dimethyl-benzeneacetonitrile;2-Methyl-2-[4-[3-met hyl-2-oxo-8-(quinolin-3-yl)-2,3-dihydroimidazo[4,5-c]quinolin-1-yl]phenyl]propionitrile;BEZ 235']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"TAK715","PubChemCID":"9952773","SMILES":"CCC1=NC(=C(S1)C2=CC(=NC=C2)NC(=O)C3=CC=CC=C3)C4=CC=CC(=C4)C","Synonyms":"['TAK-715', 'TAK 715', 'UNII-WE92U03C5Z', 'WE92U03C5Z', 'N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]benzamide', 'DTXSID20184412', 'TAK0715', 'compound 8h [PMID: 16162000]', 'compound 8h (PMID: 16162000)', 'N-{4-[2-ETHYL-4-(3-METHYLPHENYL)-1,3-THIAZOL-5-YL]PYRIDIN-2-YL}BENZAMIDE', 'N-(4-(2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl)pyridin-2-yl)benzamide', 'DTXCID30106903', '303162-79-0', 'N-(4-(2-ethyl-4-(m-tolyl)thiazol-5-yl)pyridin-2-yl)benzamide', 'Benzamide, N-[4-[2-ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]-', 'TAK715', 'CHEMBL363648', 'Benzamide, N-(4-(2-ethyl-4-(3-methylphenyl)-5-thiazolyl)-2-pyridinyl)-', 'T75', 'N-(4-(2-Ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl)-2-pyridyl)benzamide', 'MFCD17012805', 'Kinome_2655', 'MLS006011241', 'SCHEMBL297487', 'GTPL9328', 'CHEBI:91360', 'BCPP000054', 'HMS3244J06', 'HMS3244J10', 'HMS3244J14', 'HMS3265K09', 'HMS3265K10', 'HMS3265L09', 'HMS3265L10', 'HMS3651N12', 'BCP01965', 'EX-A2443', 'BDBM50173609', 'HB0599', 'NSC785339', 's2928', 'AKOS015904193', 'CCG-268646', 'CS-0073', 'NSC-785339', 'SB19426', 'NCGC00345834-01', 'NCGC00345834-05', 'AC-36073', 'AS-16239', 'HY-10456', 'SMR004703001', 'SY308217', 'TAK-715, >=98% (HPLC)', 'SW219195-1', 'D70787', 'BRD-K52751261-001-01-2', 'BRD-K52751261-001-06-1', 'BRD-K52751261-001-08-7', 'Q27163230', 'N-[4-[2-Ethyl-4-(m-tolyl)-5-thiazolyl]-2-pyridyl]benzamide', 'N-[4-[2-ethyl-4-(m-tolyl)thiazol-5-yl]-2-pyridyl]benzamide', 'N-[4-(2-Ethyl-4-m-tolyl-thiazol-5-yl)-pyridin-2-yl]-benzamide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"GF109203X","PubChemCID":"2396","SMILES":"CN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54","Synonyms":"['bisindolylmaleimide i', '133052-90-1', 'GF109203X', 'GF 109203X', 'GF-109203X', 'Go 6850', 'Go-6850', '3-(1-(3-(Dimethylamino)propyl)-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione', '3-[1-[3-(dimethylamino)propyl]indol-3-yl]-4-(1H-indol-3-yl)pyrrole-2,5-dione', 'L79H6N0V6C', '1H-Pyrrole-2,5-dione, 3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-', '2-(1-(3-Dimethylaminopropyl)indol-3-yl)-3-(indol-3-yl)maleimide', '2-[1-(3-dimethylaminopropyl)indol-3-yl]-3-(indol-3-yl)maleimide', '1H-Pyrrole-2,5-dione, 3-(1-(3-(dimethylamino)propyl)-1H-indol-3-yl)-4-(1H-indol-3-yl)-', '3-{1-[3-(DIMETHYLAMINO)PROPYL]-1H-INDOL-3-YL}-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE', 'DTXSID50157932', '3-{1-[3-(dimethylamino)propyl]-1H-indol-3-yl}-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione', '3-[1-[3-(dimethylamino)propyl]-1h-indol-3-yl]-4-(1h-indol-3-yl)-1h-pyrrole-2,5-dione', 'bisindoylmaleimide I', 'BIS-1 cpd', 'GFX 203290', 'Go6850', '3-(1-(3-(dimethylamino)propyl)indol-3-yl)-4-(1H-indol-3-yl)pyrrole-2,5-dione', '3-(1-(3-(dimethylamino)propyl)-1H-indol-3-yl)-4-(1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione', 'DTXCID3080423', '603-702-0', 'BIM-1', 'CHEMBL7463', 'Bisindolylmaleimide I (GF109203X)', 'BI1', 'Bisindolylmaleimide I (GF 109203X)', 'UNII-L79H6N0V6C', '1zrz', 'bisin-dolylmaleimide', 'MFCD00236428', 'Bisindolylmaleimide 1', 'Gouml6850', 'Tocris-0741', '1uu8', 'BIM I', 'GF-109203', 'BiomolKI_000031', 'BiomolKI2_000039', 'BMK1-D7', 'BSPBio_001160', 'KBioGR_000500', 'KBioSS_000500', 'JMC526193 Compound 2', 'SCHEMBL338086', 'BDBM2683', 'GTPL5193', 'KBio2_000500', 'KBio2_003068', 'KBio2_005636', 'KBio3_000919', 'KBio3_000920', 'CHEBI:229916', 'Bio2_000420', 'Bio2_000900', 'GLXC-10667', 'HMS1362J21', 'HMS1792J21', 'HMS1990J21', 'HMS3229A21', 'HMS3266P07', 'HMS3403J21', 'HMS3411F13', 'HMS3653O17', 'HMS3675F13', 'BCP08311', 'EX-A1223', 'EI-246', 'HSCI1_000290', 's7208', 'AKOS024458625', 'CCG-100635', 'CS-6154', 'DB03777', 'SB19439', 'SDCCGSBI-0086662.P005', 'GF 109203X?', 'IDI1_002175', 'NCGC00024760-01', 'NCGC00024760-02', 'NCGC00024760-03', 'NCGC00024760-04', 'NCGC00024760-07', 'AC-32872', 'AS-74139', 'HY-13867', 'B5781', 'NS00068321', 'SW219715-1', 'C72321', 'GF 109203X, synthetic, >=90% (HPLC)', 'Q866357', 'SR-01000597689', 'SR-01000597689-1', 'BRD-K31342827-001-05-4', 'BRD-K31342827-001-13-8', 'BRD-K31342827-001-15-3', '2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-3-yl)maleimide', '2-(1H-Indol-3-yl)-3-[1-(3-dimethylaminopropyl)-1H-indol-3-yl]-maleinimide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Imatinib","PubChemCID":"5291","SMILES":"CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5","Synonyms":"['Imatinib', '152459-95-5', 'Glamox', 'CCRIS 9076', 'UNII-BKJ8M8G5HI', 'BKJ8M8G5HI', 'NSC-743414', 'NSC-759854', '4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE', 'CHEBI:45783', '4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide', '4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide', \"alpha-(4-Methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-tolu-p-toluidide\", 'DTXSID3037125', 'NSC 743414', 'NSC 759854', '4-[(4-methylpiperazin-1-yl)methyl]-N-{4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl}benzamide', 'Benzamide, 4-((4-methyl)-1-piperazinyl)methyl)-N-(4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)phenyl)-', \"alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-toluidide\", 'BENZAMIDE, 4-((4-METHYL-1-PIPERAZINYL)METHYL)-N-(4-METHYL-3-((4-(3-PYRIDINYL)-2-PYRIMIDINYL)AMINOPHENYL)-', 'Imatinibum', '4-((4-Methyl-1-piperazinyl)methyl)-N-(4-methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)phenyl)benzamide', '4-((4-methylpiperazin-1-yl)methyl)-n-(4-methyl-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)phenyl)benzamide', '4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-(4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL)-BENZAMIDE', 'DTXCID1017125', 'L01XE01', 'STI571', 'Imatinib (STI571)', 'sti-571', 'Imatinib free base', 'N-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide', 'Cgp 57148', 'STI 571', 'Imatinib (INN)', 'CGP-57148', '152459-95-5 (free base)', 'MFCD05662257', 'CHEMBL941', 'NSC743414', 'N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide', 'IMATINIB [INN]', 'Imatinib [INN:BAN]', '4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-phenyl]benzamide', '4-[(4-methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide', 'STI', 'Glamox (TN)', 'SR-01000763561', 'NCGC00159456-02', 'ST1571', 'ST 1571', 'Imatinib base', 'imatinib-CD3', '1iep', '1xbb', 'Gleevec(TM)', '4-(4-Methylpiperazin-1-ylmethyl)-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide; CGP 57148; Genfatinib; Imatinib, Benzamide, 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-', '4-[(4-methyl-1-piperazinyl)-methyl]-N-{4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]-amino]-phenyl)-benzamide', '4-[(4-methyl-1-piperazinyl)-methyl]-N-{4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]-amino]-phenyl}-benzamide', '4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[(4-(3-pyridinyl)-2-pyrimidinyl]amino]-phenyl]benzamide', 'Imatinib (Gleevec)', 'Imatinib, 21', 'Imatinib (Standard)', 'Imatinib, Free base', 'Kinome_3724', '112GI019', 'IMATINIB [MI]', 'IMATINIB [VANDF]', 'IMATINIB [WHO-DD]', 'Gleevec (TN) (Novartis)', 'cid_5291', 'SCHEMBL3827', 'IMATINIB [EMA EPAR]', 'STI-571; IMATINIB', 'BIDD:GT0047', 'GTPL5687', 'BDBM13530', 'EX-A063', 'BCPP000205', 'GLXC-05177', 'HMS2089D03', 'HMS3244P06', 'HMS3244P10', 'HMS3244P14', 'HMS3656K04', 'HMS3715P03', 'Imatinib base - Bio-X trade mark', 'Pharmakon1600-01502276', 'BCP01542', 'AC-524', 'HY-15463R', 'NSC759854', 'NSC800772', 'STK617705', 'AKOS000280662', 'BCP9000775', 'CCG-101289', 'CS-0964', 'DB00619', 'ES-0058', 'FM10813', 'NSC-800772', 'PA-5291', 'SB17306', 'SDCCGSBI-0634386.P009', 'MRF-0000449', 'NCGC00159456-01', 'NCGC00159456-03', 'NCGC00159456-04', 'NCGC00159456-05', 'NCGC00159456-06', 'NCGC00159456-07', 'NCGC00159456-09', 'NCGC00159456-16', '4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide methanesulfonate', 'BI164570', 'HY-15463', 'N-(3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)-4-methylphenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide', 'N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide', 'SY028029', 'I0906', 'NS00009172', 'S2475', 'SW197805-5', 'D08066', 'EN300-123057', 'AB00698388-07', 'AB00698388-10', 'AB00698388-11', 'AB00698388-12', 'AB00698388-13', 'AB00698388_15', 'AB00698388_16', 'Q177094', 'SR-01000763561-4', 'SR-01000763561-6', 'BRD-K92723993-001-06-7', 'BRD-K92723993-001-12-5', 'BRD-K92723993-066-02-9', 'BRD-K92723993-066-04-5', 'BRD-K92723993-066-22-7', 'Z1546624232', '1080014-82-9', '4-(4-Me-piperazin-1-ylmethyl)-N-[4-Me-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide', '4-(4-Methylpiperazin-1-yl)methyl-N-4-methyl-3-(4-pyridin-3-ylpyrimidin-2-yl)aminophenylbenzamide', '4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide', '4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3- pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide', '4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide', '4-[(4-methyl-1-piperazinyl)methyl]-n[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-benzamide', 'benzamide, 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-', 'Benzamide, 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]- (9CI)', 'N-[4-Methyl-3-[[4-(3-pyridyl)-2-pyrimidyl]amino]phenyl]-4-[(4-methyl-1-piperazinyl)methyl]benzamide']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Salermide","PubChemCID":"135659046","SMILES":"CC(C1=CC=CC=C1)C(=O)NC2=CC(=CC=C2)N=CC3=C(C=CC4=CC=CC=C43)O","Synonyms":"['Salermide', '663-369-2', '1105698-15-4', 'N-{3-[(2-Hydroxy-naphthalen-1-ylmethylene)-amino]-phenyl}-2-phenyl-propionamide', 'CHEMBL597845', 'N-[3-[(2-Hydroxynaphthalen-1-yl)methylideneamino]phenyl]-2-phenylpropanamide', 'N-[3-[[(2-hydroxy-1-naphthalenyl)methylene]amino]phenyl]-a-methyl-benzeneacetamide', 'N-(3-(((2-Hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide', 'Salermide?', 'SCHEMBL8103931', 'Salermide, >=98% (HPLC)', 'SCHEMBL16445054', 'CHEBI:94426', 'DTXSID70693943', 'GLXC-06535', 'HMS3648G04', 'BCP19469', 'EX-A1238', 'BDBM50309827', 's8460', 'AKOS024457988', 'AKOS032947358', 'CCG-208708', 'CS-6203', 'N-[3-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]phenyl]-alpha-methylbenzeneacetamide', 'AC-35496', 'BS-14362', 'DA-77656', 'HY-101073', 'C71361', 'SR-01000946363', 'SR-01000946363-1', 'BRD-A67788537-001-01-7', 'Q27166286', 'SIRT1/2 Inhibitor VIII, Salermide - CAS 1105698-15-4', 'N-(3-((2-Hydroxynaphthalen-1-yl)methyleneamino)phenyl)-2-phenylpropanamide', 'N-[3-[(2-oxo-1-naphthalenylidene)methylamino]phenyl]-2-phenylpropanamide', '(E)-N-(3-(((2-hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide', 'N-{3-[(E)-[(2-hydroxynaphthalen-1-yl)methylidene]amino]phenyl}-2-phenylpropanamide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"TGX221","PubChemCID":"9907093","SMILES":"CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3)N4CCOCC4","Synonyms":"['TGX-221', '663619-89-4', 'Tgx 221', '7-methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-Pyrido[1,2-a]pyrimidin-4-one', 'UNII-6L28AW98TH', '6L28AW98TH', '7-Methyl-2-(morpholin-4-yl)-9-[1-(phenylamino)ethyl]pyrido[1,2-a]pyrimidin-4-one', '4H-Pyrido(1,2-a)pyrimidin-4-one, 7-methyl-2-(4-morpholinyl)-9-(1-(phenylamino)ethyl)-', '7-Methyl-2-(morpholin-4-yl)-9-(1-(phenylamino)ethyl)pyrido(1,2-a)pyrimidin-4-one', '7-methyl-2-morpholin-4-yl-9-[1-(phenylamino)ethyl]pyrido[2,1-b]pyrimidin-4-one', 'TGX221 cpd', '7-methyl-2-(4-morpholinyl)-9-(1-(phenylamino)ethyl)-4H-Pyrido(1,2-a)pyrimidin-4-one', '7-methyl-2-morpholin-4-yl-9-(1-(phenylamino)ethyl)pyrido(2,1-b)pyrimidin-4-one', 'CPRAGQJXBLMUEL-UHFFFAOYSA-N', 'TGX221', '7-methyl-2-morpholino-9-(1-(phenylamino)ethyl)-4H-pyrido[1,2-a]pyrimidin-4-one', 'CHEMBL1972466', '9-(1-Anilinoethyl)-7-methyl-2-morpholin-4-ylpyrido[1,2-a]pyrimidin-4-one', 'C21H24N4O2', 'MFCD11113209', 'Kinome_3610', 'MLS006010987', 'SCHEMBL902952', 'GTPL8244', 'CHEBI:91428', 'TGX221?', 'BCPP000046', 'DTXSID101025688', 'HMS3229L09', 'HMS3244E15', 'HMS3244E16', 'HMS3244F15', 'HMS3295M19', 'HMS3654K14', 'HMS3744G09', 'BCP01971', 'EX-A1105', 'BDBM50447094', 's1169', 'AKOS022177036', 'CCG-101299', 'CS-0110', 'SB19244', 'SDCCGSBI-0207185.P005', 'NCGC00346495-01', 'NCGC00346495-12', 'PI 3-K beta Inhibitor VI, TGX-221', 'AC-33159', 'AS-16240', 'HY-10114', 'SMR004702789', 'SW218249-2', 'BRD-A41692738-001-01-9', 'BRD-A41692738-001-07-6', 'BRD-A41692738-001-10-0', 'Q27088979', 'PI 3-Kbeta Inhibitor VI, TGX-221 - CAS 663619-89-4', '7-methyl-2-morpholin-4-yl-9-(1-phenylaminoethyl)-pyrido[1,2-a]-pyrimidin-4-one']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Ipatasertib","PubChemCID":"24788740","SMILES":"C[C@@H]1C[C@H](C2=C1C(=NC=N2)N3CCN(CC3)C(=O)[C@H](CNC(C)C)C4=CC=C(C=C4)Cl)O","Synonyms":"['Ipatasertib', '1001264-89-6', 'GDC-0068', 'RG7440', '(S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one', 'Ipatasertib [INN]', 'RG-7440', 'GDC0068', 'Ipatasertib [USAN:INN]', '524Y3IB4HQ', 'IPATASERTIB [USAN]', 'RG 7440', 'IPATASERTIB [WHO-DD]', '1-Propanone, 2-(4-chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-, (2S)-', 'DTXSID101025595', '(2S)-2-(4-Chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta(d)pyrimidin-4-yl)piperazin-1-yl(-3-((propan-2-yl)amino)propan-1-one', '1-Propanone, 2-(4-chlorophenyl)-1-(4-((5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl)-1-piperazinyl)-3-((1-methylethyl)amino)-, (2S)-', '2-(4-chlorophenyl)-1-(4-(7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta(d)pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one', '(2S)-2-(4-chlorophenyl)-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[e]pyrimidin-4-yl]piperazin-1-yl]-3-(propan-2-ylamino)propan-1-one', 'ipatasertibum', '(2S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-5H,6H,7H-cyclopenta(d)pyrimidin-4-yl)piperazin-1-yl)-3-((propan-2-yl)amino)propan-1-one', '(2S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta(e)pyrimidin-4-yl)piperazin-1-yl)-3-(propan-2-ylamino)propan-1-one', '(2S)-2-(4-chlorophenyl)-1-{4-[(5R,7R)-7-hydroxy-5-methyl-5H,6H,7H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl}-3-[(propan-2-yl)amino]propan-1-one', '(S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta(d)pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one', 'DTXCID301509858', '825-519-7', 'Ipatasertib (GDC-0068)', '(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone', 'CHEMBL2177390', '(2S)-2-(4-chlorophenyl)-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl]-3-(propan-2-ylamino)propan-1-one', 'MFCD22124514', 'GDC 0068', '(2s)-2-(4-Chlorophenyl)-1-{4-[(5r,7r)-7-Hydroxy-5-Methyl-6,7-Dihydro-5h-Cyclopenta[d]pyrimidin-4-Yl]piperazin-1-Yl}-3-(Propan-2-Ylamino)propan-1-One', 'GDC-0068; Ipatasertib; RG 7440;', 'UNII-524Y3IB4HQ', 'GDC0068 di-HCl', 'Ipatasertib (USAN/INN)', 'GDC-0068 di-HCl', 'Ipatasertib; GDC-0068', 'RG-7440 di-HCl', 'SCHEMBL191659', 'GTPL7887', 'CHEBI:95089', 'GRZXWCHAXNAUHY-NSISKUIASA-N', 'EX-A2077', 'BDBM50398379', 'NSC767898', 'NSC781451', 'NSC800986', 'NSC832484', 's2808', 'AKOS025396463', 'BCP9000712', 'CCG-269312', 'CS-0975', 'DB11743', 'NSC-767898', 'NSC-781451', 'NSC-800986', 'NSC-832484', 'SDCCGSBI-0654476.P001', 'NCGC00346714-01', 'AC-28420', 'AS-17027', 'HY-15186', 'BCP0726000195', 'NS00072927', 'D10641', 'Q27078088', '0RF']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Sorafenib","PubChemCID":"216239","SMILES":"CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F","Synonyms":"['Sorafenib', '284461-73-0', 'sorafenibum', '4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide', 'UNII-9ZOQ3TZI87', '9ZOQ3TZI87', 'BAY-43-9006', \"N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea\", '4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide', '4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide', 'DTXSID7041128', 'CHEBI:50924', 'HSDB 8173', 'BAY43-9006', 'EC 608-209-4', 'BAY-439006', 'SORAFENIB (MART.)', 'SORAFENIB [MART.]', '4-(4-{3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide', '4-(4-(((4-chloro-3-(trifluoromethyl)phenyl)carbamoyl)amino)phenoxy)-N-methylpyridine-2-carboxamide', '4-(4-(3-(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)UREIDO)PHENOXY)-N(SUP 2)-METHYLPYRIDINE-2-CARBOXAMIDE', 'sorafenib tosilate hydrate', 'DTXCID5021128', 'L01XE05', 'BA4 43 9006', '4-(4-(3-(4-chloro-3-trifluoromethylphenyl)ureido)phenoxy)pyridine-2-carboxyllic acid methyamide-4-methylbenzenesulfonate', 'BAY 43-9006', '4-(4-(3-(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)UREIDO)PHENOXY)-N-METHYLPICOLINAMIDE', 'Sorafenib free base', '4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide', '100012-18-8', 'MFCD06411450', '4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide', '284461-73-0 (free base)', 'CHEMBL1336', '4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE', 'Sorafenib [INN]', '2-Pyridinecarboxamide, 4-(4-((((4-chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-', 'Sorafenib (Nexavar)', 'NSC-724772', 'NCGC00167488-01', 'Sorafenib [USAN:INN:BAN]', 'SR-00000000529', '1uwh', '3gcs', '3heg', '4asd', 'Hit compound, 8', 'Sorafenib, 4', \"4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide; BAY 43-9006; N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea; Nevaxar; Sorafenib\", \"Manganese(4+), chloro[[4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl-kappaN21,kappaN22,kappaN23,kappaN24)tetrakis[1-methylpyridiniumato]](2-)]-, chloride (1:4), (SP-5-12)-\", 'Sorafenib (Standard)', 'BAY 439006', 'Kinome_766', 'SORAFENIB BASE', 'SORAFENIB [MI]', 'Sorafenib (USAN/INN)', 'SORAFENIB [USAN]', 'Nexavar (TN) (Bayer)', 'SORAFENIB [VANDF]', 'SCHEMBL8218', 'SORAFENIB [WHO-DD]', 'SORAFENIB [EMA EPAR]', 'Sorafenib - Bio-X trade mark', 'BAY 43-9006; Sorafenib', 'cid_216239', 'GTPL5711', 'BDBM16673', 'BCPP000064', 'HMS2043A18', 'HMS3244A15', 'HMS3244A16', 'HMS3244B15', 'HMS3656N20', 'K00597a', 'BCP01767', 'BCP34023', 'EX-A2894', 'BAY439006', 'HY-10201R', 'NSC747971', 'NSC800934', 's7397', 'STK627350', 'AKOS005560229', 'AC-1674', 'CCG-269400', 'CS-1590', 'DB00398', 'FS10807', 'NSC-747971', 'NSC-800934', 'PB14443', 'SB19942', 'SDCCGSBI-0634413.P005', 'SF-0529', 'BAY-43-0006', 'NCGC00167488-02', 'NCGC00167488-03', 'NCGC00167488-04', 'NCGC00167488-05', 'NCGC00167488-07', 'NCGC00167488-11', 'NCGC00167488-14', '4(4-{3-[4-Chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide', 'BS164413', 'DA-52659', 'HY-10201', \"N-(4-chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcar bamoyl)-4-pyridyloxy)phenyl)urea\", 'Sorafenib free base (BAY-43-9006)?', 'SY009239', 'PA-216239', 'NS00005946', 'SW202562-4', 'D08524', 'EN300-120647', 'AB00933189-05', 'AB00933189-06', 'AB00933189_08', 'Q421136', 'SR-00000000529-1', 'BRD-K23984367-001-01-8', 'BRD-K23984367-001-07-5', 'BRD-K23984367-075-15-2', 'Z89277543', 'BAY 439006; BAY439006; BAY-439006', 'Sorafenib (D3); CM-4307; CM 4307; CM4307;Bay 43-9006 (D3)', '4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl) ureido) phenoxy)-N-methylpicolinamide', '4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl) ureido)phenoxy)-N-methylpicolinamide', \"N-(3-trifluoromethyl-4-chlorophenyl)-N'-(4-(2-methylcarbamoyl pyridin-4-yl)oxyphenyl)urea\", '4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N(sup 2)- methylpyridine-2-carboxamide', '4-(4-(3-(4-chloro-3-trifluoromethylphenyl)ureido)phenoxy)pyridine-2- carboxyllic acid methyamide-4-methylbenzenesulfonate', '4-(4-{3-[4-chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)- N-methylpyridine-2-carboxamide', '4-(4-{3-[4-Chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)-N2-methylpyridine-2-carboxamide', '4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-picolinamide;tosylic acid', '4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)-amino]phenoxy}-N-methylpyridine-2-carboxamide', '4-{4-[({[4-chloro-3-(trifluoromethyl)phenyl]amino}carbonyl)amino]phenoxy}-N-methyl-pyridine-2-carboxamide', \"Manganese(4+), chloro[[4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl-N21,N22,N23,N24)tetrakis[1-methylpyridiniumato]](2-)]-, chloride (1:4), (SP-5-12)-\", \"N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4- pyridyloxy)phenyl)urea\", \"N-(4-chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl) urea\"]","Type":"small molecule"},{"Action":"not found","PerturbationName":"Gossypetin","PubChemCID":"5280647","SMILES":"C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)O)O)O)O","Synonyms":"['Gossypetin', '489-35-0', 'Articulatidin', 'Equisporol', \"3,5,7,8,3',4'-Hexahydroxyflavone\", \"3,3',4',5,7,8-Hexahydroxyflavone\", 'UNII-SET4M23ZTM', 'SET4M23ZTM', '8-hydroxyquercetin', '2-(3,4-Dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-chromen-4-one', 'CHEBI:16400', '4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-', 'DTXSID50197631', '8-hydroxy-quercetin', 'C.I.-75750', \"FLAVONE, 3,3',4',5,7,8-HEXAHYDROXY-\", '2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy-chromen-4-one', 'DTXCID10120122', '2-(3,4-Dihydroxyphenyl)-3,5,7,8-tetrahydroxychromen-4-one', 'CHEMBL253570', 'MFCD00017680', 'BSPBio_002552', 'SCHEMBL157033', 'SPECTRUM1505143', 'BDBM26655', 'GLXC-06243', 'LMPK12113231', 'AKOS024283047', 'AT33743', 'CCG-231029', 'FH46598', 'NCGC00096031-01', 'NCGC00096031-02', 'NCGC00178604-01', 'BP-10444', 'MS-24692', 'DB-051591', 'HY-119917', 'CS-0078364', 'C04109', \"Gossypetin,3,3',4',5,7,8-Hexahydroxyflavone\", 'SR-05000002577', 'Q3036428', 'SR-05000002577-1', 'BRD-K06692906-001-01-6', '2-(3,4-Dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-chromen-4-one #']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Chir99021","PubChemCID":"9956119","SMILES":"CC1=CN=C(N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N","Synonyms":"['252917-06-9', 'CHIR-99021', 'laduviglusib', 'CHIR 99021', 'CT99021', 'CT-99021', '6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile', 'CHIR-911', 'CT 99021', 'Laduviglusib [USAN]', 'CHR00921', '6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile', '234CMT4GK4', 'CHIR 911', 'CHR-00921', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile', 'LADUVIGLUSIB [INN]', 'CHEBI:91091', 'DTXSID90179931', '3-Pyridinecarbonitrile, 6-((2-((4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl)amino)ethyl)amino)-', 'Laduviglusib (USAN)', '6-[(2-{[4-[2,4-Dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]NH}ethyl)NH]pyridine-3-CN', '6-((2-((4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)pyridine-3-carbonitrile', '6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl)NH)ethyl)NH)pyridine-3-CN', '6-(2-((4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethylamino)pyridine-3-carbonitrile', 'DTXCID50102422', '809-015-4', 'CHIR99021', '6-[2-[4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino]ethylamino]pyridine-3-carbonitrile', 'Laduviglusib (GMP)', 'FX03', '6-((2-((4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile', 'CHIR-99021 (CT99021)', 'CHEMBL412142', '[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile', '252917-06-9 (free base)', 'CHIR 99021 Hydrochloride Salt', 'GSK-3 Inhibitor XVI', '6-(2-(4-(2,4-dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-ylamino)ethylamino)nicotinonitrile', 'UNII-234CMT4GK4', '6-[(2-([4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino)ethyl)amino]pyridine-3-carbonitrile', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile', '65C', 'MFCD11846251', 'Kinome_3785', 'Laduviglusib (Standard)', 'SCHEMBL151139', 'GTPL8014', 'EX-A535', 'BCPP000285', 'HMS3295O15', 'BCP01901', 'BDBM50325983', 'HB1261', 'HY-10182G', 'HY-10182R', 's1263', 'WHO 11473', 'AKOS015904410', 'AKOS026750421', 'BCP9000520', 'CCG-269402', 'CS-0181', 'FD43329', 'SB19266', 'SDCCGSBI-0654265.P001', 'CHIR-99021,CT99021', 'NCGC00250379-01', 'NCGC00250379-03', 'NCGC00250379-09', 'NCGC00250379-21', '6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile', '6-[2-[[4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile', 'AC-25532', 'AS-16523', 'HY-10182', 'SY016322', 'C2943', 'CHIR99021, >=98% (HPLC)', 'CS-0615620', 'CHIR-99021 (CT99021)?', 'D12196', 'EN300-18520201', 'GSK-3 Inhibitor XVI - CAS 252917-06-9', 'BRD-K16189898-001-02-9', 'BRD-K16189898-001-04-5', 'BRD-K16189898-001-09-4', 'BRD-K16189898-001-10-2', 'BRD-K16189898-001-11-0', 'BRD-K16189898-001-15-1', 'BRD-K16189898-003-03-3', 'Q27075965', '6-[(2-{[4-(2,4-dichlorophenyl) -5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol -2-yl)-pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)-pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino }ethyl)amino]pyridine-3-carbonitrile', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(4-methylimidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3 -carbonitrile', '6-[(2-{[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino}ethyl)amino]pyridine-3-carbonitrile', '6-[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-2-imidazolyl)-2-pyrimidinyl]amino]ethylamino]-3-pyridinecarbonitrile', '6-{2-[4-(2,4-dichloro-phenyl)-5-(4-methyl-1h-imidazol-2-yl)-pyrimidin-2-ylamino]-ethylamino}-nicotinonitrile', '6-{2-[4-(2,4-dichloro-phenyl)-5-(5-methyl-1h-imidazol-2-yl)-pyrimidin-2-ylamino]-ethylamino}-nicotinonitrile']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"AC220","PubChemCID":"24889392","SMILES":"CC(C)(C)C1=CC(=NO1)NC(=O)NC2=CC=C(C=C2)C3=CN4C5=C(C=C(C=C5)OCCN6CCOCC6)SC4=N3","Synonyms":"['Quizartinib', '950769-58-1', 'AC220', 'AC-220', 'AC 220', 'AC220 compound', 'AC010220', 'Quizartinib [USAN]', 'quizartinibum', 'Quizartinib [USAN:INN]', 'AC 010220', 'ASP-2689', '7LA4O6Q0D3', \"N-(5-tert-Butylisoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea\", 'CHEBI:90217', 'QUIZARTINIB [MI]', 'QUIZARTINIB [INN]', 'QUIZARTINIB [WHO-DD]', 'AC-010220', 'DTXSID70241746', '1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morpholin-4-Yl)ethoxy]imidazo[2,1-B][1,3]benzothiazol-2-Yl}phenyl)urea', '1-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[6-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea', \"N-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea\", \"N-(5-(1,1-Dimethylethyl)isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-yl)ethoxy)imidazo(2,1-b)benzothiazol-2-yl)phenyl)urea\", \"Urea, N-(5-(1,1-dimethylethyl)-3-isoxazolyl)-N'-(4-(7-(2-(4-morpholinyl)ethoxy) imidazo(2,1-b)benzothiazol-2-yl)phenyl)-\", '1-(5-TERT-BUTYL-1,2-OXAZOL-3-YL)-3-(4-(7-(2-(MORPHOLIN-4-YL)ETHOXY)IMIDAZO(2,1-B)(1,3)BENZOTHIAZOL-2-YL)PHENYL)UREA', '3-(5-tert-butyl-1,2-oxazol-3-yl)-1-(4-{10-[2-(morpholin-4-yl)ethoxy]-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(12),3,5,8,10-pentaen-4-yl}phenyl)urea', \"N-(5-TERT-BUTYLISOXAZOL-3-YL)-N'-(4-(7-(2-(MORPHOLIN-4-YL)ETHOXY)IMIDAZO(2,1-B)(1,3)BENZOTHIAZOL-2-YL)PHENYL)UREA\", '1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-(6-(2-morpholin-4-ylethoxy)imidazo(2,1-b)(1,3)benzothiazol-2-yl)phenyl)urea', '3-(5-tert-butyl-1,2-oxazol-3-yl)-1-(4-(10-(2-(morpholin-4-yl)ethoxy)-7-thia-2,5-diazatricyclo(6.4.0.0^(2,6))dodeca-1(12),3,5,8,10-pentaen-4-yl)phenyl)urea', '3-(5-tert-butyl-1,2-oxazol-3-yl)-1-(4-(10-(2-(morpholin-4-yl)ethoxy)-7-thia-2,5-diazatricyclo(6.4.0.02,?)dodeca-1(8),3,5,9,11-pentaen-4-yl)phenyl)urea', '3-(5-tert-butyl-1,2-oxazol-3-yl)-1-(4-{10-[2-(morpholin-4-yl)ethoxy]-7-thia-2,5-diazatricyclo[6.4.0.02,?]dodeca-1(8),3,5,9,11-pentaen-4-yl}phenyl)urea', \"N-(5-tert-butyl-isoxazol-3-yl)-N'-(4-(7-(2-morpholin-4-yl-ethoxy)imidazo (2,1-b) (1,3) benzothiazol 2-yl)phenyl)urea\", \"N-(5-tert-butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo [2,1-b] [1,3] benzothiazol 2-yl]phenyl}urea\", \"N-(5-tert-Butylisoxazol-3-yl)-N'-(4-(7-(2-morpholin-4-ylethoxy)imidazo(2,1-b)(1,3)benzothiazol-2-yl)phenyl)urea\", 'DTXCID00164237', 'L01XE52', '107-677-2', 'Quizartinib (AC220)', '1-(5-(tert-butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea', 'Quizartinib HCl', 'Quizartinib freebase', 'CHEMBL576982', '950769-58-1 (free base)', '1132827-21-4 (HCl)', \"n-(5-tert-butyl-isoxazol-3-yl)-n'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea dihydrochloride\", 'CHEMBL2386811', \"N-(5-(1,1-Dimethylethyl)isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-yl)ethoxy)imidazo(2,1- b)benzothiazol-2-yl)phenyl)urea\", 'AC220,Quizartinib', 'UNII-7LA4O6Q0D3', 'MFCD18074524', 'Quizartinib, 95%', 'Quizartinib, ac220', 'Quizartinib (Standard)', 'Quizartinib, Free Base', 'AC 220 dihydrochloride', 'Quizartinib; PLX3397', 'Quizartinib (AC220)?', 'Quizartinib (USAN/INN)', 'SCHEMBL72923', 'MLS006011240', 'GTPL5658', 'CVWXJKQAOSCOAB-UHFFFAOYSA-N', 'BCPP000443', 'HMS3244K09', 'HMS3244K10', 'HMS3244L09', 'HMS3265G09', 'HMS3265G10', 'HMS3265H09', 'HMS3265H10', 'HMS3654J20', 'HMS3743G21', 'BCP02224', 'HVB82721', 'BDBM50300690', 'HY-13001R', 'NSC756647', 'NSC799659', 'NSC800857', 's1526', 'AKOS015891557', 'BCP9000223', 'CCG-264906', 'CS-0211', 'DB12874', 'FQ32834', 'NSC-756647', 'NSC-799659', 'NSC-800857', 'SB16610', 'SDCCGSBI-0647186.P001', 'NCGC00242493-01', 'NCGC00242493-02', 'NCGC00242493-07', '1-(5-(tert-Butyl)isoxazol-3-yl)-3-(4-(7-(2-morpholinoethoxy)-benzo[d]imidazo[2,1-b]thiazol-2-yl)phenyl)urea', 'AS-16178', 'HY-13001', 'SMR004703000', 'NS00072561', 'SW218131-2', 'D09955', 'Q7272714', 'BRD-K93918653-001-01-4', 'BRD-K93918653-001-08-9', \"AC 010220; Quizartinib; N-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea;\", \"N-(5-tert-Butyl-isoxazol-3-yl)-N''-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea\", \"N-(5-Tert-butyl-isoxazol-3-yl)-N'-(4-(7-(2-(morpholin-4-ylethoxy)imidazo(2,1-b) (1,3)benzothiazol-2-yl)phenyl)urea\", \"N-(5-tert-Butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea\"]","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Trametinib","PubChemCID":"11707110","SMILES":"CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5","Synonyms":"['Trametinib', '871700-17-3', 'TMT212', 'trametinibum', 'UNII-33E86K87QN', 'CHEBI:75998', 'TMT-212', '33E86K87QN', 'MEK Inhibitor GSK1120212', 'L01XE25', 'GSK1120212', 'Mekinist', 'GSK-1120212', 'JTP 74057', 'Trametinib (GSK1120212)', 'JTP-74057', 'GSK 1120212', 'N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide', 'Trametinib [USAN]', 'MFCD17215075', 'N-(3-(3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide', 'N-(3-{3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl}phenyl)acetamide', 'Trametinib (USAN)', 'N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide', 'Trametinib [USAN:INN]', 'Trametinib?', 'JTP74057', 'N-(3-(3-Cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7- tetrahydropyrido(4,3-d)pyrimidin-1(2H)-yl)phenyl)acetamide', 'N-(3-{3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7- tetrahydropyrido(4,3-d)pyrimidin-1(2H)-yl}phenyl)acetamide', 'N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide', 'QOM', 'Trametinib (Standard)', 'TRAMETINIB [MI]', 'TRAMETINIB [INN]', 'TRAMETINIB [VANDF]', 'TRAMETINIB [WHO-DD]', 'SCHEMBL170938', 'GTPL6495', 'GSK1120212 (Trametinib)', 'CHEMBL2103875', 'EX-A022', 'LIRYPHYGHXZJBZ-UHFFFAOYSA-N', 'BCPP000218', 'DTXSID901007381', 'HMS3295I05', 'HMS3656J11', 'BCP02307', 'BDBM50531540', 'HY-10999R', 'NSC758246', 'NSC800956', 's2673', 'AKOS015850628', 'CCG-264976', 'CS-0060', 'DB08911', 'EX-5957', 'FC34128', 'NSC-758246', 'NSC-800956', 'SB16553', 'SDCCGSBI-0646933.P001', 'NCGC00263180-01', 'NCGC00263180-07', 'NCGC00263180-14', 'AC-25891', 'AS-19382', 'HY-10999', 'N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodo-anilino)-6,8-dimethyl-2,4,7-trioxo-pyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide', 'SY067882', 'NS00040692', 'SW218089-2', 'D10175', 'EN300-25299821', 'GSK1120212,JTP-74057, GSK212', 'SR-01000941589', 'Q7833138', 'SR-01000941589-1', 'BRD-K12343256-001-01-4', 'BRD-K12343256-001-08-9', 'BRD-K12343256-001-11-3', 'BRD-K12343256-001-14-7', 'BRD-K12343256-001-18-8', 'Acetamide, N-(3-(3-cyclopropyl-5-((2-fluoro-4-iodophenyl)amino)-3,4,6,7-tetrahydro-6,8- dimethyl-2,4,7-trioxopyrido(4,3-d)pyrimidin-1(2H)-yl)phenyl)-', 'Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-', 'N-(3-(3-Cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)pheny  l)acetamide', 'N-(3-(3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl)phenyl)acetamide', 'N-(3-{3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxo-1H,2H,3H,4H,6H,7H-pyrido[4,3-d]pyrimidin-1-yl}phenyl)acetamide', 'N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-6,8-dimethyl-2,4,7-trioxopyrido[3,4-e]pyrimidin-1-yl]phenyl]acetamide', 'N-{3-[3-Cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydropyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl}ethanimidic acid', 'N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodophenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Calpain inhibitor ii","PubChemCID":"121855","SMILES":"CC(C)C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C=O)NC(=O)C","Synonyms":"['Calpain inhibitor II', '110115-07-6', 'ALLM', 'N-acetylleucyl-leucyl-methioninal', 'N-Allm', 'Calpain inhibitor 2', 'N-Acetyl-leu-leu-methioninal', 'Cpi(2)', 'CHEMBL318779', 'SUAM-312', '1D8SBU367Z', 'CHEBI:7209', '(2S)-2-acetamido-4-methyl-N-[(2S)-4-methyl-1-[[(2S)-4-methylsulfanyl-1-oxobutan-2-yl]amino]-1-oxopentan-2-yl]pentanamide', 'N-Acetyl-L-leucyl-L-leucyl-L-methioninal', 'ALLM (Calpain Inhibitor)', 'UNII-1D8SBU367Z', 'Ac-Leu-Leu-Met-al', 'Ac-Leu-Leu-Met-H', 'Ac-Leu-Leu-Methional; ALLM', 'Calpain Inhibitor II, powder', 'CI 2', 'SCHEMBL2162504', 'N-Acetylleucyl-leucyl-methininal', 'DTXSID90911499', 'GLXC-05404', 'GLXC-23177', 'BDBM50421409', 'AKOS040741088', 'L-Leucinamide, N-acetyl-L-leucyl-N-(1-formyl-3-(methylthio)propyl)-, (S)-', 'CCG-207842', 'FC29615', 'HY-118355', 'ALLM - CAS 110115-07-6', 'CS-0065741', 'G12173', 'Q27107457', 'N-Acetyl-L-leucyl-N-(1-formyl-3-mercaptopropyl)-L-leucinamide (S)', 'L-LEUCINAMIDE, N-ACETYL-L-LEUCYL-N-((1S)-1-FORMYL-3-(METHYLTHIO)PROPYL)-', '(2S)-2-acetamido-N-[(1S)-1-[[(1S)-1-formyl-3-methylsulfanyl-propyl]carbamoyl]-3-methyl-butyl]-4-methyl-pentanamide', '2-[(1-Hydroxyethylidene)amino]-N-(1-hydroxy-4-methyl-1-{[4-(methylsulfanyl)-1-oxobutan-2-yl]imino}pentan-2-yl)-4-methylpentanimidic acid']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Milrinone","PubChemCID":"4197","SMILES":"CC1=C(C=C(C(=O)N1)C#N)C2=CC=NC=C2","Synonyms":"['milrinone', '78415-72-2', 'Milrinona', 'Milrinonum', 'Milrila', 'Milrinonum [Latin]', 'Win-47203-2', \"1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile\", 'YM 018', 'CCRIS 3795', 'UNII-JU9YAX04C7', 'EINECS 278-903-6', 'JU9YAX04C7', 'NSC-760072', 'BRN 3546821', 'DTXSID5023324', 'WIN 47,203-2', 'CHEBI:50693', \"2-methyl-6-oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile\", \"(3,4'-BIPYRIDINE)-5-CARBONITRILE, 1,6-DIHYDRO-2-METHYL-6-OXO-\", 'DTXCID103324', \"(3,4'-Bipyridine)-5-carbonitrile, 6-dihydro-2-methyl-6-oxo-\", 'Milrinone [USAN:USP:INN:BAN]', 'Milrinonum (Latin)', 'NSC 760072', \"[3,4'-Bipyridine]-5-carbonitrile, 1,6-dihydro-2-methyl-6-oxo-\", 'MILRINONE (MART.)', 'MILRINONE [MART.]', 'MILRINONE (USP-RS)', 'MILRINONE [USP-RS]', 'MILRINONE (USP MONOGRAPH)', 'MILRINONE [USP MONOGRAPH]', 'Milrinone (USAN:USP:INN:BAN)', 'C01CE02', '278-903-6', 'Primacor', 'MFCD00133539', \"2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile\", '6-methyl-2-oxo-5-(pyridin-4-yl)-1,2-dihydropyridine-3-carbonitrile', '6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile', 'WIN 47203', \"1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile\", 'Corotrope', 'CHEMBL189', 'NCGC00015675-08', 'NCGC00164390-01', 'Milrinona [Spanish]', 'CAS-78415-72-2', '2-hydroxy-6-methyl-5-pyridin-4-ylpyridine-3-carbonitrile', \"1,6-Dihydro-2-methyl-6-oxo-[3,4'-bipyridine]-5-carbonitrile\", \"2-Methyl-6-oxo-1,6-dihydro-[3,4']bipyridinyl-5-carbonitrile\", 'SMR000058475', 'Milrila (TN)', 'WIN 47203-2', 'SR-01000075524', '3-Cyano-6-methyl-5-(4-pyridyl)-2-pyridone', 'Milrinone?', \"1,6-Dihydro-2-methyl-6-oxo-[3,4'-bipyridine]-5-carbonitrile;Corotrope;Milrila\", 'Milrinone(Primacor)', '6-Methyl-5-(4-pyridyl)-2-pyridone-3-carbonitrile', 'Milrinone (Primacor)', 'Milrinone (Standard)', 'Tocris-1504', '111GE027', 'MILRINONE [INN]', 'MILRINONE [JAN]', 'MILRINONE [MI]', 'MILRINONE [USAN]', '1,2-DIHYDRO-6-METHYL-2-OXO-5-(4-PYRIDINYL)NICOTINONITRILE', 'Prestwick0_001065', 'Prestwick1_001065', 'Prestwick2_001065', 'Prestwick3_001065', 'Lopac-M-4659', 'MILRINONE [VANDF]', 'M1663', \"2-Methyl-6-oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile (Milrinone)\", 'M 4659', 'MILRINONE [WHO-DD]', 'Milrinone (JAN/USP/INN)', 'Lopac0_000737', 'SCHEMBL36947', 'BSPBio_001050', 'MLS000028818', 'MLS001424052', 'MLS006011946', 'BIDD:GT0197', 'Milrinone - Bio-X trade mark', 'SPBio_002965', 'BPBio1_001156', 'GTPL5225', 'SCHEMBL8309385', 'BDBM15296', 'GLXC-06520', 'HMS1571E12', 'HMS2051L10', 'HMS2090J14', 'HMS2098E12', 'HMS2234A23', 'HMS3262C16', 'HMS3267P12', 'HMS3370H18', 'HMS3393L10', 'HMS3656G06', 'HMS3715E12', 'HMS3742G09', 'Pharmakon1600-01505489', 'BCP02956', 'Tox21_112113', 'Tox21_400069', 'Tox21_500737', 'HY-14252R', 'Milrinone, >=97% (TLC), powder', 'NSC760072', 's2484', 'Milrinone - CAS 78415-72-2', 'AKOS015836135', 'Tox21_112113_1', 'AC-4730', 'BCP9000926', 'CCG-101020', 'CCG-204822', 'CS-1367', 'DB00235', 'FM26007', 'KS-1440', 'LP00737', 'NC00270', 'SDCCGSBI-0050715.P002', 'NCGC00015675-01', 'NCGC00015675-02', 'NCGC00015675-03', 'NCGC00015675-04', 'NCGC00015675-05', 'NCGC00015675-06', 'NCGC00015675-07', 'NCGC00015675-09', 'NCGC00015675-11', 'NCGC00015675-24', 'NCGC00025189-01', 'NCGC00025189-02', 'NCGC00025189-03', 'NCGC00261422-01', 'BM164671', 'HY-14252', 'SMR004703527', 'SY028050', 'BCP0726000256', 'AB00514027', 'EU-0100737', 'NS00007740', 'SW197308-3', 'C07224', 'D00417', 'EN300-117244', 'AB00514027-02', 'AB00514027-03', 'AB00514027_04', 'AB00514027_05', 'AB00597139-08', 'A839417', 'Q847399', 'SR-01000075524-1', 'SR-01000075524-3', 'SR-01000075524-4', 'SR-01000075524-6', 'BRD-K67080878-001-05-5', 'BRD-K67080878-001-15-4', 'BRD-K67080878-001-16-2', 'Z1501480412', '1,2-dihydro-6-methyl-2-oxo-5-(4 -pyridinyl)nicotinonitrile', 'Milrinone, United States Pharmacopeia (USP) Reference Standard', '1,2-DIHYDRO-6-METHYL-2-OXO-5-(4-PYRIDINYL)-NICOTINONITRILE', '6-methyl-2-oxidanylidene-5-pyridin-4-yl-1H-pyridine-3-carbonitrile', '1,6-Dihydro-2-methyl-6-oxo-(3,4 inverted exclamation mark -bipyridine)-5-carbonitrile']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Neratinib","PubChemCID":"9915743","SMILES":"CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)/C=C/CN(C)C","Synonyms":"['Neratinib', '698387-09-6', 'UNII-JJH94R3PWB', 'JJH94R3PWB', '(2E)-N-[4-[[3-chloro-4-[(pyridin-2-yl)methoxy]phenyl]amino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide', 'PB-272', 'CDP-820', 'PB 272', 'CHEBI:61397', 'DTXSID70220132', '(2E)-N-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide', 'N-(4-(3-Chloro-4-(2-pyridinylmethoxy)anilino)-3-cyano-7-ethoxy-6-quinolyl)-4-(dimethylamino)-2-butenamide', 'NERATINIB (MART.)', 'NERATINIB [MART.]', '(2e)-n-(4-((3-chloro-4-((pyridin-2-yl)methoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide', '2-Butenamide, N-(4-((3-chloro-4-(2-pyridinylmethoxy)phenyl)amino)-3-cyano-7-ethoxy-6-quinolinyl)-4-(dimethylamino)-, (2E)-', 'neratinibum', '(2E)-N-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide', '(2E)-N-[4-({3-chloro-4-[(pyridin-2-yl)methoxy]phenyl}amino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide', 'DTXCID70142623', 'L10XE45', 'HKI-272', 'Neratinib (HKI-272)', 'HKI 272', '(E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide', 'CHEMBL180022', '(E)-N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide', '698387-09-6 (free base)', 'HKI272', 'WAY-179272', '(2E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide', '(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide', 'Neratinib [USAN]', 'Neratinib [USAN:INN]', 'MFCD09752958', 'Neratinib (Standard)', 'NERATINIB [INN]', 'NERATINIB [MI]', 'Neratinib (USAN/INN)', 'NERATINIB [WHO-DD]', 'Neratinib (HKI-272)?', 'SCHEMBL571762', 'SCHEMBL571763', 'Neratinib - Bio-X trade mark', 'GTPL5686', 'EX-A062', 'BCPP000151', 'BDBM50161957', 'HY-32721R', 'NSC757439', 'NSC800803', 's2150', 'WAY-179272-B', 'AKOS005146340', 'AKOS025149637', 'BCP9000984', 'CCG-270036', 'DB11828', 'FN65101', 'NSC-757439', 'NSC-800803', 'SDCCGSBI-0654392.P001', 'NCGC00241101-01', 'NCGC00241101-03', 'NCGC00241101-08', 'NCGC00241101-09', 'AC-25073', 'AS-16279', 'BN164645', 'HY-32721', 'N1062', 'NS00069565', 'D08950', 'EN300-7386009', 'Q6995920', 'BRD-K85606544-001-01-8', 'BRD-K85606544-001-09-1', '(E)-4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide', '4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide', 'N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide', 'N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)butanamide']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Sotrastaurin","PubChemCID":"10296883","SMILES":"CN1CCN(CC1)C2=NC3=CC=CC=C3C(=N2)C4=C(C(=O)NC4=O)C5=CNC6=CC=CC=C65","Synonyms":"['Sotrastaurin', '425637-18-9', 'AEB071', 'Sotrastaurin (AEB071)', 'AEB-071', '3-(1H-Indol-3-yl)-4-(2-(4-methylpiperazin-1-yl)quinazolin-4-yl)-1H-pyrrole-2,5-dione', 'sotrastaurina', 'sotrastaurine', '3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione', 'NVP-AEB071', 'CHEBI:90531', '7I279E1NZ8', '3-(1h-Indol-3-Yl)-4-[2-(4-Methylpiperazin-1-Yl)quinazolin-4-Yl]-1h-Pyrrole-2,5-Dione', '1H-Pyrrole-2,5-dione, 3-(1H-indol-3-yl)-4-(2-(4-methyl-1-piperazinyl)-4-quinazolinyl)-', '949935-06-2', 'Sotrastaurin [USAN]', 'Sotrastaurin [USAN:INN]', 'sotrastaurinum', 'Sotrastaurin?', 'UNII-7I279E1NZ8', 'C25H22N6O2', 'Kinome_2717', 'Sotrastaurin (Standard)', 'Sotrastaurin (USAN/INN)', 'SOTRASTAURIN [INN]', 'NVP-AEB-071', 'SOTRASTAURIN [WHO-DD]', 'CHEMBL565612', 'GTPL7946', 'SCHEMBL2500835', 'BDBM33971', 'DTXSID70915192', 'OAVGBZOFDPFGPJ-UHFFFAOYSA-N', 'HMS3656D10', 'HMS3673M05', 'HMS3744G03', 'BCP07456', 'EX-A2802', 'HY-10343R', 'NSC766819', 'NSC800935', 's2791', 'AKOS027422723', 'CCG-264999', 'CS-0090', 'DB12369', 'NSC-766819', 'NSC-800935', 'SB16638', 'SDCCGSBI-0654474.P001', 'NCGC00238621-01', 'NCGC00238621-09', 'AC-32050', 'AS-56373', 'DA-58019', 'HY-10343', 'NS00069692', 'SW220235-1', 'D09671', 'L10095', 'BRD-K16761703-001-03-8', 'Q26331952', '3-(1H-indol-3-yl)-4-[2-(4-methyl-piperazin-1-yl)-quinazolin-4-yl]-pyrrole-2,5-dione', '1058706-31-2', '5-Hydroxy-4-(1H-indol-3-yl)-3-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-2H-pyrrol-2-one', 'LW4']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Pd0325901","PubChemCID":"9826528","SMILES":"C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOC[C@@H](CO)O","Synonyms":"['391210-10-9', 'PD0325901', 'Mirdametinib', 'PD 0325901', 'PD-0325901', 'N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide', 'Mirdametinib [USAN]', 'PD 325901', 'PD325901', '86K0J5AK6M', 'DTXSID0044024', 'Mirdametinib (USAN)', 'CHEBI:88249', 'MIRDAMETINIB [INN]', 'MIRDAMETINIB [WHO-DD]', 'DTXCID8024024', 'Pd 901', 'Benzamide, N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-', 'Pd 03525901', 'N-[((R)-2,3-dihydroxypropyl)oxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide', 'Benzamide, N-((2R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)-', 'N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide', '(-)-N-(((R)-2,3-DIHYDROXYPROPYL)OXY)-3,4-DIFLUORO-2-((2-FLUORO-4-IODOPHENYL)AMINO)BENZAMIDE', 'N-((2R)-2,3 Dihydroxypropoxy)-3,4 Difluro-2-((2-Fluoro-4-Iodophenyl)Amino) Benzamide', 'N-((2R)-2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide', 'N-[(2R)-2,3 Dihydroxypropoxy]-3,4 Difluro-2-[(2-Fluoro-4-Iodophenyl)Amino] Benzamide', 'N-(((R)-2,3-DIHYDROXYPROPYL)OXY)-3,4-DIFLUORO-2-((2-FLUORO-4-IODOPHENYL)AMINO)BENZAMIDE', 'N-((2R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-((2-FLUORO-4-IODOPHENYL)AMINO)-BENZAMIDE', 'MEK Inhibitor PD0325901', 'N-(((R)-2,3-DIHYDROXYPROPYL)OXY)-3,4-DIFLUORO-2-((2-FLUORO-4-IODOPHENYL)AMINO)BENZAMIDE N-((2R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODOANILINO)BENZAMIDE', '(R)-N-(2,3-Dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide', 'PD-325901', '(R)-N-(2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODOPHENYLAMINO)BENZAMIDE', 'GOMEKLI', 'CHEMBL507361', 'N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzamide', 'N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide', 'NCGC00189075-01', '391209-97-5', 'MFCD08435926', 'N-((R)-2,3-dihydroxy-propoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide', 'UNII-86K0J5AK6M', 'C16H14F3IN2O4', 'N-[(R)-2,3-Dihydroxy-propoxy]-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide', '4BM', 'Gomekli (TN)', 'Mirdametinib (GMP)', 'PD0325901(Mirdametinib)', 'SCHEMBL172904', 'GTPL7935', 'PD0325901 (Mirdametinib)', 'EX-A102', 'BCPP000126', 'BDBM104963', 'HMS3648A14', 'Tox21_113364', 'HB2240', 'HY-10254G', 'NSC755770', 'NSC800840', 'PD-901', 's1036', 'WHO 11299', 'AKOS015855518', 'BCP9001057', 'CCG-221316', 'CS-0062', 'DB07101', 'EX-8602', 'FP26781', 'NSC-755770', 'NSC-800840', 'SDCCGSBI-0654263.P002', 'NCGC00381744-09', 'HY-10254', 'US8575391, Q', 'CAS-391210-10-9', 'NS00069616', 'SW218101-2', 'PD-03525901', 'D11675', 'PD-0325901,PD325901', 'PD 0325901, >=98% (HPLC)', 'SR-01000946344', 'SR-01000946344-1', 'BRD-K49865102-001-01-9', 'BRD-K49865102-001-08-4', 'Q27088255', 'N-((R)-2,3-Dihydroxy[propoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide', 'N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]- benzamide']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Afuresertib","PubChemCID":"46843057","SMILES":"CN1C(=C(C=N1)Cl)C2=C(SC(=C2)C(=O)N[C@@H](CC3=CC(=CC=C3)F)CN)Cl","Synonyms":"['Afuresertib', 'GSK-2110183', 'GSK2110183C', 'Afuresertib [USAN]', 'ASB183', 'ASB-183', 'Afuresertib [USAN:INN]', 'GSK 2110183C', 'UNII-8739X25QI3', 'AFURESERTIB [INN]', '8739X25QI3', 'AFURESERTIB [WHO-DD]', 'DTXSID60146711', 'Afuresertib (USAN)', '2-Thiophenecarboxamide, N-((1S)-2-amino-1-((3-fluorophenyl)methyl)ethyl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-', 'N-((1S)-1-(aminomethyl)-2-(3-fluorophenyl)ethyl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide', 'N-((2S)-1-AMINO-3-(3-FLUOROPHENYL)PROPAN-2-YL)-5-CHLORO-4-(4-CHLORO-1-METHYL-1H-PYRAZOL-5-YL)THIOPHENE-2-CARBOXAMIDE', 'N-[(2S)-1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide', 'afuresertibum', 'N-[(1S)-1-(Aminomethyl)-2-(3-fluorophenyl)ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide', 'DTXCID0069202', 'gsk-2110183c', 'gsk2110183', '1047644-62-1', 'Afuresertib (GSK2110183)', 'N-[(2S)-1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methylpyrazol-3-yl)thiophene-2-carboxamide', 'GSK 2110183', 'N-((S)-1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide', 'Afuresertib?', 'Afuresertib (USAN/INN)', 'SCHEMBL187686', 'GTPL7890', 'CHEMBL2219422', 'AFJRDFWMXUECEW-LBPRGKRZSA-N', 'CHEBI:131168', '2-Thiophenecarboxamide, N-[(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-;2-Thiophenecarboxamide, N-[(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl]-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-', 'BCP08435', 'EX-A1574', 'BDBM50502477', 'NSC778305', 'NSC781255', 'NSC800109', 'NSC829868', 's7521', 'AKOS030526224', 'CCG-268972', 'CS-3384', 'DB11648', 'NSC-778305', 'NSC-781255', 'NSC-800109', 'NSC-829868', 'NCGC00387879-03', 'AC-35761', 'BA166066', 'BS-14212', 'DA-50259', 'HY-15727', 'NS00072544', 'D10381', 'D71036', 'Afuresertib, GSK-2110183, GSK-2110183B', 'BRD-K25412176-001-01-9', 'Q27224945', 'GSK 2110183C;N- [(1S) - 2- Amino- 1- [(3- fluorophenyl) methyl] ethyl] - 5- chloro- 4- (4- chloro- 1- methyl- 1H- pyrazol- 5- yl) -2  - thiophenecarboxamide', 'N-[(2S)-1-amino-3-(3-fluorophenyl)propan-2-yl]-5-chloro-4-(4-chloro-2-methyl-3-pyrazolyl)-2-thiophenecarboxamide', 'N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"AZD3759","PubChemCID":"78209992","SMILES":"C[C@@H]1CN(CCN1C(=O)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC)C","Synonyms":"['AZD3759', 'AZD-3759', 'zorifertinib', 'AZD 3759', 'UNII-67SX9H68W2', 'ZORIFERTINIB [INN]', 'ZORIFERTINIB [WHO-DD]', '[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl] (2R)-2,4-dimethylpiperazine-1-carboxylate', 'compound 1m [PMID: 26313252]', 'compound 1m (PMID: 26313252)', '1-PIPERAZINECARBOXYLIC ACID, 2,4-DIMETHYL-, 4-((3-CHLORO-2-FLUOROPHENYL)AMINO)-7-METHOXY-6-QUINAZOLINYL ESTER, (2R)-', '(4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl) (2R)-2,4-dimethylpiperazine-1-carboxylate', '4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl 2,4-dimethylpiperazine-1-carboxylate', '1626387-80-1', '(R)-4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl 2,4-dimethylpiperazine-1-carboxylate', '4-[(3-CHLORO-2-FLUOROPHENYL)AMINO]-7-METHOXYQUINAZOLIN-6-YL (2R)-2,4-DIMETHYLPIPERAZINE-1-CARBOXYLATE', '67SX9H68W2', 'CHEMBL3623290', '(2R)-2,4-dimethyl-1-piperazinecarboxylic acid, 4-[(3-chloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl ester', '4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl (2R)-2,4-dimethylpiperazine-1-carboxylate', 'MFCD29058564', 'C22H23ClFN5O3', 'SCHEMBL16010006', 'GTPL10456', 'EX-A720', 'GLXC-90388', 'BDBM50123453', 'NSC788121', 'NSC800978', 's7971', 'AKOS027327321', 'CCG-269329', 'CS-5029', 'DB14795', 'NSC-788121', 'NSC-800978', 'NCGC00483922-01', 'NCGC00483922-02', 'AC-29957', 'AS-74755', 'FA137650', 'HY-18750', 'BRD-K41626799-001-01-1', 'Z2471604138', '(R)-4-(3-chloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yl 2,4-dimethylpiperazine-1-carboxylate']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Bms","PubChemCID":"9833925","SMILES":"[B].CSC","Synonyms":"['13292-87-0', 'borane dimethyl sulfide', 'Dimethyl sulphide borane', 'Boron, trihydro[thiobis[methane]]-, (T-4)-', 'Boron, trihydro(thiobis(methane))-, (T-4)-', 'Di-methylsulfide borane', 'Dimethyl sulphide--borane', 'EINECS 236-313-6', 'EC 236-313-6', 'Boron, trihydrothiobismethane-, (T-4)-', 'Methyl sulfide, compd. with borane (1:1)', '6ave9srr08', 'boron, trihydro(thiobis(methane))-', 'trihydro(dimethyl sulfide)boron', 'Dimethyl sulfide borane', 'borane dimethylsulfide', 'Borane-dimethyl sulfide', 'Methyl Sulfide Borane', 'BMS', 'MFCD00013189', 'Dimethyl sulfideborane', 'boron;methylsulfanylmethane', 'borane DMS', 'borane Me2S', 'DMS Borane', 'borane methylsulfide', 'borane dimethylsulfid', 'borane methylsulphide', 'boron dimethylsulfide', 'boron methyl sulfide', 'borane dimethylsulfane', 'borane methyl sulfide', 'borane.dimethylsulfide', 'Dimethylsulfide borane', 'borane dimethylsulphide', 'borane-dimethy sulfide', 'boron dimethyl sulfide', 'boron dimethyl-sulfide', 'Borane methyl sulphide', 'borane dimethyl-sulfide', 'dimethyl sulfide-borane', 'borane dimethyl sulphide', 'BH3.DMS', 'boron; (methylthio)methane', 'boron; methylsulfanylmethane', '(Methylsulfanyl)methane borane', 'RMHDLBZYPISZOI-UHFFFAOYSA-N', 'BCP12489', 'AKOS015833633', '(Methylthio)methane compound with borane', 'D1843', 'Borane dimethyl sulfide complex 2.0 M in THF', 'D89934', 'A806532']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Ribociclib","PubChemCID":"44631912","SMILES":"CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5","Synonyms":"['Ribociclib', '1211441-98-3', 'LEE011', 'LEE-011', 'LEE 011', '7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide', 'LEE011A', 'UNII-TK8ERE8P56', 'TK8ERE8P56', '7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide', 'LEE-011A', 'example 74 (US8962630)', 'example 74 [US8962630]', '7H-PYRROLO(2,3-D)PYRIMIDINE-6-CARBOXAMIDE, 7-CYCLOPENTYL-N,N-DIMETHYL-2-((5-(1-PIPERAZINYL)-2-PYRIDINYL)AMINO)-', 'ribociclibum', '7-Cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo(2,3-d)pyrimidine-6-carboxamide', 'L01XE42', 'Ribociclib (LEE011)', 'Kisqali', '7-cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide', '7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide', '7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7H-pyrrolo [2,3-d]pyrimidine-6-carboxylic acid dimethylamide', '7-Cyclopentyl-N,N-dimethyl-2-(5-(piperazin-1-yl)pyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide', 'Ribociclib [INN]', 'Ribociclib, LEE011', 'Ribociclib [USAN:INN]', '7H-Pyrrolo[2,3-d]pyrimidine-6-carboxamide, 7-cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-; 7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; Kisqali; LEE 011; LEE 011A; Ribociclib', 'MFCD27976795', 'Ribociclib (Standard)', 'RIBOCICLIB [MI]', 'Ribociclib (USAN/INN)', 'RIBOCICLIB [USAN]', 'Ribociclib (LEE011)?', 'NVP-LEE011', 'RIBOCICLIB [WHO-DD]', 'SCHEMBL302310', 'GTPL7383', 'CHEMBL3545110', 'EX-A304', 'CHEBI:230905', 'RHXHGRAEPCAFML-UHFFFAOYSA-N', 'BDBM148264', 'DTXSID201021027', 'HMS3653N03', 'HMS3673I19', 'HMS3748M05', 'BCP08804', 'HY-15777R', 'NSC778909', 'NSC794613', 'NSC800867', 's7440', 'AKOS025404915', 'AKOS032949987', 'CCG-269070', 'CS-1750', 'DB11730', 'NSC-778909', 'NSC-794613', 'NSC-800867', 'SB18480', 'NCGC00386317-10', 'NCGC00386317-11', 'AC-30029', 'AS-10159', 'DA-35904', 'FR106414', 'HY-15777', 'LEE-011; LEE 011;LEE011', 'NS00072964', 'SW220101-1', 'D10883', 'EN300-7409093', 'US8962630, 74', 'BRD-K36788280-001-01-2', 'BRD-K36788280-001-03-8', 'BRD-K36788280-001-04-6', 'Q27088552', '6ZZ', '7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Sirolimus","PubChemCID":"5284616","SMILES":"C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC","Synonyms":"['rapamycin', 'Sirolimus', '53123-88-9', '(-)-Rapamycin', 'Rapamune', 'rapalimus', 'AY-22989', 'Supralimus', 'WY-090217', 'HYFTOR', 'sirolimusum', 'Cypher', 'Antibiotic AY 22989', 'RAPA', 'Rapammune', 'CCRIS 9024', 'CHEBI:9168', 'SILA 9268A', 'W36ZG6FT64', 'HSDB 7284', 'L04AA10', 'SM-88 COMPONENT SIROLIMUS', 'DE-109', 'NSC-226080', 'UNII-W36ZG6FT64', 'DTXSID5023582', 'NAB-RAPAMYCIN COMPONENT RAPAMYCIN', 'SIROLIMUS (MART.)', 'SIROLIMUS [MART.]', 'EC 610-965-5', 'NSC 226080', 'SIROLIMUS (USP-RS)', 'SIROLIMUS [USP-RS]', 'AY 22989', 'NSC226080', 'Wy 090217', '(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-{(2S)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0(4,9)]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone', 'EVEROLIMUS IMPURITY A (EP IMPURITY)', 'EVEROLIMUS IMPURITY A [EP IMPURITY]', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone', 'DTXCID503582', '(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((2S)-1-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)propan-2-yl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-((2R)-1-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)propan-2-yl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido(2,1-c)(1,4)oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone', 'RPM', 'S01XA23', '(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone', '610-965-5', '9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,2', '(3 s,6 r,7 e,9 r,10 r,12 r,14 s,15 e,17 e, 19 e,21 s,23 s,26 r,27 r,34a s)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34, 34a-hexadecahydro-9,27-dihydroxy-3-', '23,27-epoxy-3h-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4h,6h,31h)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-(3-(4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-, (3s-(3r*(s*(1r*,3s*,4s*)),6s*,7e,9s*,10s*,12s*,14r*,15e,17e,19e,21r*,23r*,26s*,27s*,34ar*))-', 'I 2190A', 'I-2190A', 'I2190A', 'SIIA 9268A', 'Rapamycin (Sirolimus)', 'Rapamycin (GMP)', 'FYARRO', 'Npc-12g', 'Rapamycin (GMP Like)', 'MFCD00867594', 'Rapamycin Immunosuppressant Drug', 'Rapamycin (>85%)', '(-)-Rapamycin;Sirolimus', 'Perceiva', '1fkb', '1pbk', 'NCGC00021305-05', 'Rapamycin/Sirolimus', 'LCP-Siro', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(1R)-2-[(1S,3R,4R)-4-hydroxy-3-(methyloxy)cyclohexyl]-1-methylethyl}-6,8,12,14,20,26-hexamethyl-10,21-bis(methyloxy)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(6H,31H)-pentone', 'RAP', 'Rapamycin (Standard)', 'S1039', 'Rapamycin (Sirolimus)?', 'SIROLIMUS [INN]', 'SIROLIMUS [JAN]', 'RAPAMYCIN [MI]', 'Human Blood - Sirolimus', 'SIROLIMUS [HSDB]', 'SIROLIMUS [USAN]', 'SIROLIMUS [VANDF]', 'BiomolKI2_000084', 'SCHEMBL3463', 'SIROLIMUS [WHO-DD]', 'Rapamycin,Sirolimus,Rapamune', 'BIDD:PXR0165', 'SIROLIMUS [EMA EPAR]', '23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine', 'MLS006010168', 'Sirolimus [USAN:INN:BAN]', 'Rapamycin - Bio-X trade mark', 'GTPL6031', 'SIROLIMUS [ORANGE BOOK]', 'BDBM36609', 'MS-R001', 'GLXC-06448', 'HMS2089A21', 'HMS3403F11', 'HMS3884C03', 'HY-10219GL', 'EX-A1044', 'AC-722', 'BDBM50064359', 'HB2779', 'HY-10219G', 'HY-10219R', 'STL570275', 'AKOS015850976', 'AKOS015961618', 'AE27685', 'CCG-100684', 'CS-0063', 'DB00877', 'NCGC00021305-06', 'NCGC00021305-07', 'AS-11687', 'BR164324', 'HY-10219', 'SMR004701276', 'Fyarro (sirolimus albumin-bound particles)', 'UNM-0000358684', 'A-275', 'CS-0626126', 'CS-1010374', 'R0097', 'Rapamycin, VETRANAL(TM), analytical standard', 'M02444', 'Q32089', 'BRD-K84937637-001-04-0', 'BRD-K84937637-001-06-5', 'BRD-K84937637-001-09-9', 'BRD-K84937637-001-11-5', 'BRD-K84937637-001-13-1', 'BRD-K89626439-001-01-0', 'Z2568665260', '24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypy', 'Rapamycin from Streptomyces hygroscopicus, >=95% (HPLC), powder', 'Rapamycin from Streptomyces hygroscopicus, Vetec(TM) reagent grade, >=95%', '(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-{(2S)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone', '(3 S ,6 R ,7 E ,9 R ,10 R ,12 R ,14 S ,15 E ,17 E , 19 E ,21 S ,23 S ,26 R ,27 R ,34a S )-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34, 34a-hexadecahydro-9,27-dihydroxy-3-', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34 aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hex adecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydro xy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy- 6,8,12,14,20,26-hexamethyl-23,27-ep', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-4,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-223,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(6H,31H)-pentone', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-ep', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(1R)-2-[(1S,3R,4R)-4-hydroxy-3-(methyloxy)cyclohexyl]-1-methylethyl}-6,8,12,14,20,26-hexamethyl-10,21-bis(methyloxy)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone', '(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,', '1,18-Dihydroxy-12-[2-(4-hydroxy-3-methoxy-cyclohexyl)-1-methyl-ethyl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-aza-tricyclo[30.3.1.0*4,9*]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone (Rapamycin)']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Pd","PubChemCID":"23938","SMILES":"[Pd]","Synonyms":"['PALLADIUM', '7440-05-3', 'paladio', 'Palladium, element', 'PD', '46Pd', '5TWQ1V240M', 'CHEBI:33363', 'HSDB 6768', 'METALLIC PALLADIUM', 'EINECS 231-115-6', 'PALLADIUM METALLICUM', 'UNII-5TWQ1V240M', 'DTXSID4064680', 'DTXCID2047644', '231-115-6', '237-859-8', 'Palladium on carbon', 'Palladium Black', 'Palladium on barium sulfate', 'Palladium on alumina', 'Pd/C', 'Palladium powder', 'Palladium on barium carbonate', 'Palladium, elemental', 'Palladium on strontium carbonate', 'MFCD00011167', 'Palladium 10% on Carbon (wetted with ca. 55% Water)', 'Palladium powder, -200 mesh', 'Palladium sponge', 'Palladium granules', 'MFCD03457879', 'Palladium Black 99.9%', 'Palladium 5% on Carbon (wetted with ca. 55% Water)', 'palladium on charcoal', 'Palladium Standard: Pd @ 1000 microg/mL in 20% HCl', 'Palladium Standard: Pd @ 1000 microg/mL in 5% HNO3', 'Palladium Standard: Pd @ 10000 microg/mL in 20% HCl', 'Palladium AA Standard: Pd @ 1000 microg/mL in 20% HCl', 'Palladium Standard: Pd @ 10000 microg/mL in 10% HNO3', 'Palladium Nitrate GFAA Matrix Modifier: 1% Pd in 10% HNO3', 'Palladium (5% on Barium Sulfate)', 'Palladium Hollow Cathode Lamp: 1.5\" Diameter, 2-pin, Non-Coded', 'Palladium Hollow Cathode Lamp: 2.0\" Diameter, 4-pin, Cableless', 'Palladium Hollow Cathode Lamp: 2.0\" Diameter, 9-pin, Non-Coded', 'MFCD03427452', 'MFCD03613602', 'MFCD03613603', 'MFCD03613604', 'MFCD03613605', 'Sulfur-Free Barium Concentrate: Ba @ approx. 7 wt% in Hydrocarbons', 'Palladium element', 'Palladium wire, 1.0mm (0.04in) dia', 'Palladium foil, 0.5mm (0.02in) thick', 'Palladium wire, 0.25mm (0.01in) dia', 'Palladium foil, 0.25mm (0.01in) thick', 'Palladex 600', 'Palladium (5% on Alumina Powder, Reduced, Dry)', 'Palladium (5% on Calcium Carbonate, Lead poisoned)', 'palladiumblack', 'hydridopalladium', 'palladium-black', 'Palladiumelement', 'Palladium foil', 'Palladium wire', 'palladium/carbon', 'palladium/silica', 'palladiumcharcoal', 'palladium/alumina', 'Pd on charcoal', 'Pd on alumina', 'Pd on carbon', 'palladium charcoal', 'palladium-charcoal', 'palladium/charcoal', 'palladium /carbon', 'palladium/ carbon', 'palladium(0)', 'Palladium Nanorods', 'palladium on cabon', 'Palladium On Carbon (extent of labeling: 10 wt. % loading, matrix carbon, dry support)', 'palladiumon alumina', 'palladium (0)', 'palladium-on carbon', 'palladium-on-carbon', 'palladium-on-silica', 'palladium/char coal', 'palladiumon charcoal', 'Palladium Nanoprisms', 'palladium-on-alumina', 'palladium- on-carbon', 'paliadium-on-charcoal', 'Palladium Metal Foil', 'palladium on-charcoal', 'Palladium shot, 3N', 'palladium-on charcoal', 'Palladium on car-bon', 'Pd on barium sulfate', 'Precipitated palladium', 'PALLADIUM 5% ON BARIUM SULFATE', 'Palladium powder, 5N', 'palladium- on-charcoal', 'palladium/barium sulfate', 'Palladium rod, 3N5+', 'palladium -on- charcoal', 'PALLADIUM [MI]', 'PALLADIUM [HSDB]', 'Palladium Nano Dispersion', 'palladium on bariumsulfate', 'palladium/barium carbonate', 'Palladium, 10% on carbon, Type 487, dry', 'palladium/calcium carbonate', 'Palladium 5% on Al2O3', 'Epitope ID:114072', 'palladium on charcoal paste', 'PALLADIUM [WHO-DD]', 'sulfided palladium on carbon', 'Palladium, 10% on Silica', 'Palladium, Powder 200 Mesh', 'Ultra Thin Palladium Nanofoil', '10% Palladium on carbon wet', 'Palladium nanopowder (20 nm)', 'Palladium, 5% on carbon, dry', 'Palladium 10% on carbon powder', 'HSDB 7330', 'Palladium 5% on Barium Carbonate', 'Palladium 5% on carbon dry powder', 'PALLADIUM METALLICUM [HPUS]', 'BCP01442', 'MFCD06798745', 'Palladium 10% on Carbon, dry basis', 'Palladium sponge, -100+325 mesh', 'AKOS005259069', 'Palladium, 0.5% on alumina, reduced', 'Palladium, 5% on 3mm alumina pellets', 'FP38632', 'Palladium powder, -22 mesh, Premion?', '10% palladium on carbon (50% water)', 'Palladium wire, 0.5mm (0.02in) dia', 'Palladium on activated carbon - 10% Pd', 'BP-11458', 'Gallium(III) Chloride Anhydrous (GaCl3)', 'Palladium black, Vetec(TM) reagent grade', 'Palladium foil, 1.0mm (0.04in) thick', 'Palladium, 1% on alumina powder, reduced', 'Palladium 10% on Carbon, wet 50% Water', 'Palladium black surface area 40-60 m2/g', 'Palladium foil, 0.1mm (0.004in) thick', 'Palladium on barium sulfate, 5% Pd basis', 'Palladium black, surface area 40-60 m2/g', 'Palladium on barium sulfate, 10% Pd basis', 'CS-0017899', 'NS00082603', 'P1490', 'P1491', 'P1701', 'P1702', 'P1703', 'P1785', 'P2238', 'Palladium black, 99.99% trace metals grade', 'Palladium wire, 0.127mm (0.005in) dia', 'Palladium, 5% on carbon powder, Type 490', 'Q1089', 'Palladium foil, 0.025mm (0.001in) thick', 'Palladium, 0.5% on 2-4 mm alumina spheres', 'Palladium, sponge, 99.9% trace metals basis', 'Palladium, 5% on alumina, reduced, dry powder', 'Palladium-Pd @ 1000 microg/mL in 20% HCl', 'Palladium-Pd @ 1000 microg/mL in 5% HNO3', 'Palladium wire, 0.05mm (0.002in) dia, hard', 'Palladium, 5% on barium sulfate powder, reduced', 'Palladium, granular, 99.99% trace metals basis', 'Palladium, powder, 99.999% trace metals basis', 'Palladium - Pd @ 1000 microg/mL in 20% HCl', 'Palladium - Pd @ 1000 microg/mL in 5% HNO3', 'Palladium powder, spherical, APS 0.5-1.7 micron', 'Palladium wire, 0.203mm (0.008in) dia, hard', 'Palladium wire, 0.25mm (0.01in) dia, Premion?', 'Palladium wire, 0.5mm (0.02in) dia, Premion?', 'Palladium, 5% on barium sulfate powder, unreduced', 'Palladium, 5% on calcium carbonate, lead poisoned', 'Palladium foil, 1.0mm (0.04in) thick, Premion?', 'Palladium on carbon 10%, wet, contains 67% water', 'Palladium wire, 0.4mm (0.0159in) dia, annealed', 'Palladium, rod, 100mm, diameter 2.0mm, 99.95%', 'Palladium, rod, 100mm, diameter 4.0mm, 99.95%', 'Palladium, rod, 10mm, diameter 6.0mm, 99.95%', 'Palladium, rod, 25mm, diameter 2.0mm, 99.95%', 'Palladium, rod, 25mm, diameter 4.0mm, 99.95%', 'Palladium, rod, 25mm, diameter 6.0mm, 99.95%', 'Palladium, rod, 50mm, diameter 2.0mm, 99.95%', 'Palladium, rod, 50mm, diameter 4.0mm, 99.95%', 'Palladium, rod, 50mm, diameter 6.0mm, 99.95%', 'Palladium wire, 0.1mm (0.004in) dia, Premion(R)', 'Palladium wire, 0.406mm (0.016in) dia, as drawn', 'P123456000', 'Palladium 5% on Calcium Carbonate (poisoned with Lead)', 'Palladium, powder, <75 mum, 99.9% trace metals basis', 'Palladium Nanoparticles Dispersion (Pd, Purity: 99.99%)', 'Palladium, foil, 10mm disks, thickness 0.006mm, 99.95%', 'Palladium, foil, 10mm disks, thickness 0.008mm, 99.95%', 'Palladium, foil, 15mm disks, thickness 0.006mm, 99.95%', 'Palladium, foil, 15mm disks, thickness 0.008mm, 99.95%', 'Palladium, foil, 25mm disks, thickness 0.008mm, 99.95%', 'Palladium, foil, 4mm disks, thickness 0.006mm, 99.95%', 'Palladium, foil, 4mm disks, thickness 0.008mm, 99.95%', 'Palladium, foil, 4mm disks, thickness 0.0125mm, 99.95%', 'Palladium, foil, 6mm disks, thickness 0.006mm, 99.95%', 'Palladium, foil, 6mm disks, thickness 0.008mm, 99.95%', 'Palladium, foil, 6mm disks, thickness 0.0125mm, 99.95%', 'Palladium, foil, 8mm disks, thickness 0.006mm, 99.95%', 'Palladium, foil, 8mm disks, thickness 0.008mm, 99.95%', 'Palladium, foil, 8mm disks, thickness 0.0125mm, 99.95%', 'Palladium, powder, <1 mum, >=99.9% trace metals basis', 'Palladium, wire, diam. 0.1 mm, 99.9% trace metals basis', 'Palladium, wire, diam. 0.5 mm, 99.9% trace metals basis', 'Palladium, wire, diam. 1.0 mm, 99.9% trace metals basis', 'Lindlar Catalyst 5% on Calcium Carbonate (poisoned with Lead)', 'Palladium, 10% on carbon, Type 487, nominally 50% water wet', 'Palladium, 20% on carbon (dry basis), 45-65% wetted  powder', 'Palladium, 5% on alumina powder, reduced, dry (Escat 1241)', 'Palladium, 5% on carbon, Type 87L, nominally 50% water wet', 'Palladium, 5% on charcoal paste, Type 39, 50-65% water wet', 'Palladium, 5% on silica powder, reduced, dry (Escat 1351)', 'Palladium, foil, 10mm disks, thickness 0.0125mm, 99.95%', 'Palladium, foil, 15mm disks, thickness 0.0125mm, 99.95%', 'Palladium, foil, thickness 0.05 mm, 99.9% trace metals basis', 'Palladium, foil, thickness 0.5 mm, 99.9% trace metals basis', 'Palladium, foil, thickness 1.0 mm, 99.9% trace metals basis', 'Palladium, nanopowder, <25 nm particle size (TEM), >=99.5%', 'Palladium, rod, diam. 3.1 mm, >=99.9% trace metals basis', 'Palladium, rod, diam. 6.25 mm, >=99.9% trace metals basis', 'Palladium, wire reel, 0.05m, diameter 1.0mm, hard, 99.95%', 'Palladium, wire reel, 0.1m, diameter 0.25mm, hard, 99.95%', 'Palladium, wire reel, 0.1m, diameter 1.0mm, hard, 99.95%', 'Palladium, wire reel, 0.2m, diameter 1.0mm, hard, 99.95%', 'Palladium, wire reel, 0.5m, diameter 0.25mm, hard, 99.95%', 'Palladium, wire reel, 0.5m, diameter 1.0mm, hard, 99.95%', 'Palladium, wire reel, 10m, diameter 0.25mm, hard, 99.95%', 'Palladium, wire reel, 1m, diameter 0.05mm, as drawn, 99.9%', 'Palladium, wire reel, 1m, diameter 0.125mm, hard, 99.95%', 'Palladium, wire reel, 1m, diameter 0.25mm, hard, 99.95%', 'Palladium, wire reel, 1m, diameter 0.5mm, as drawn, 99.95%', 'Palladium, wire reel, 25m, diameter 0.125mm, hard, 99.95%', 'Palladium, wire reel, 2m, diameter 0.25mm, hard, 99.95%', 'Palladium, wire reel, 2m, diameter 0.5mm, as drawn, 99.95%', 'Palladium, wire reel, 50m, diameter 0.125mm, hard, 99.95%', 'Palladium, wire reel, 5m, diameter 0.05mm, as drawn, 99.9%', 'Palladium, wire reel, 5m, diameter 0.125mm, hard, 99.95%', 'Palladium, wire reel, 5m, diameter 0.25mm, hard, 99.95%', 'Palladium on alumina, extent of labeling: 1 wt. % loading, powder', 'Palladium on alumina, extent of labeling: 5 wt. % loading, dry', 'Palladium on alumina, extent of labeling: 5 wt. % loading, powder', 'Palladium on barium sulfate (5 wt. % on barium sulfate, unreduced)', 'Palladium slug, 6.35mm (0.25in) dia x 6.35mm (0.25in) length', 'Palladium, 0.5% on 3.18mm (0.125in) alumina pellets, reduced', 'Palladium, 5% on calcium carbonate, unreduced, dry (Escat 1371)', 'Palladium, 5% on charcoal paste, Type 58, nominally 50% water wet', 'Palladium, foil, 100x100mm, thickness 0.1mm, as rolled, 99.95%', 'Palladium, foil, 10x10mm, thickness 0.50mm, as rolled, 99.95%', 'Palladium, foil, 10x10mm, thickness 0.50mm, as rolled, 99.99+%', 'Palladium, foil, 25x25mm, thickness 0.125mm, as rolled, 99.95%', 'Palladium, foil, 25x25mm, thickness 0.1mm, as rolled, 99.95%', 'Palladium, foil, 25x25mm, thickness 0.1mm, as rolled, 99.99+%', 'Palladium, foil, 25x25mm, thickness 0.25mm, as rolled, 99.95%', 'Palladium, foil, 25x25mm, thickness 0.25mm, as rolled, 99.99+%', 'Palladium, foil, 25x25mm, thickness 0.50mm, as rolled, 99.95%', 'Palladium, foil, 25x25mm, thickness 0.50mm, as rolled, 99.99+%', 'Palladium, foil, 4mm disks, thickness 0.02mm, as rolled, 99.95%', 'Palladium, foil, 4mm disks, thickness 0.03mm, as rolled, 99.95%', 'Palladium, foil, 4mm disks, thickness 0.25mm, as rolled, 99.95%', 'Palladium, foil, 4mm disks, thickness 0.50mm, as rolled, 99.95%', 'Palladium, foil, 50x50mm, thickness 0.125mm, as rolled, 99.95%', 'Palladium, foil, 50x50mm, thickness 0.1mm, as rolled, 99.95%', 'Palladium, foil, 50x50mm, thickness 0.1mm, as rolled, 99.99+%', 'Palladium, foil, 50x50mm, thickness 0.25mm, as rolled, 99.95%', 'Palladium, foil, 50x50mm, thickness 0.25mm, as rolled, 99.99+%', 'Palladium, foil, 6mm disks, thickness 0.02mm, as rolled, 99.95%', 'Palladium, foil, 6mm disks, thickness 0.03mm, as rolled, 99.95%', 'Palladium, foil, 6mm disks, thickness 0.25mm, as rolled, 99.95%', 'Palladium, foil, 6mm disks, thickness 0.50mm, as rolled, 99.95%', 'Palladium, foil, 8mm disks, thickness 0.02mm, as rolled, 99.95%', 'Palladium, foil, 8mm disks, thickness 0.03mm, as rolled, 99.95%', 'Palladium, foil, 8mm disks, thickness 0.25mm, as rolled, 99.95%', 'Palladium, foil, 8mm disks, thickness 0.50mm, as rolled, 99.95%', 'Palladium, foil, thickness 0.025 mm, 99.9% trace metals basis', 'Palladium, foil, thickness 0.25 mm, 99.98% trace metals basis', 'Palladium, foil, thickness 0.60 mm, 4 mm diameter, purity 99.95%', 'Palladium, foil, thickness 0.60 mm, 8 mm diameter, purity 99.95%', 'Palladium, foil, thickness 0.60 mm, diameter 6 mm, purity 99.95%', 'Palladium, wire reel, 0.1m, diameter 0.125mm, hard, 99.95%', 'Palladium, wire reel, 0.1m, diameter 0.25mm, as drawn, 99.99+%', 'Palladium, wire reel, 0.1m, diameter 0.5mm, as drawn, 99.95%', 'Palladium, wire reel, 0.2m, diameter 0.25mm, as drawn, 99.99+%', 'Palladium, wire reel, 0.2m, diameter 0.5mm, as drawn, 99.95%', 'Palladium, wire reel, 0.2m, diameter 1.0mm, as drawn, 99.99+%', 'Palladium, wire reel, 0.5m, diameter 0.02mm, as drawn, 99.95%', 'Palladium, wire reel, 0.5m, diameter 0.05mm, as drawn, 99.9%', 'Palladium, wire reel, 0.5m, diameter 0.125mm, hard, 99.95%', 'Palladium, wire reel, 0.5m, diameter 0.25mm, as drawn, 99.99+%', 'Palladium, wire reel, 0.5m, diameter 0.5mm, as drawn, 99.95%', 'Palladium, wire reel, 10m, diameter 0.025mm, as drawn, 99.9%', 'Palladium, wire reel, 10m, diameter 0.05mm, as drawn, 99.9%', 'Palladium, wire reel, 1m, diameter 0.025mm, as drawn, 99.9%', 'Palladium, wire reel, 1m, diameter 0.02mm, as drawn, 99.95%', 'Palladium, wire reel, 1m, diameter 0.25mm, as drawn, 99.99+%', 'Palladium, wire reel, 20m, diameter 0.025mm, as drawn, 99.9%', 'Palladium, wire reel, 2m, diameter 0.025mm, as drawn, 99.9%', 'Palladium, wire reel, 2m, diameter 0.02mm, as drawn, 99.95%', 'Palladium, wire reel, 2m, diameter 0.25mm, as drawn, 99.99+%', 'Palladium, wire reel, 5m, diameter 0.025mm, as drawn, 99.9%', 'Palladium, wire reel, 5m, diameter 0.02mm, as drawn, 99.95%', 'Palladium, wire, 0.04 mm diameter, length 1 m, purity 99.95%', 'Palladium black surface area 40-60 m2/g, 99.95% trace metals basis', 'Palladium black, surface area 40-60 m2/g, 99.95% trace metals basis', 'Palladium on alumina extent of labeling: 5 wt. % loading, dry, bead/balls', 'Palladium on alumina, extent of labeling: 0.5 wt. % loading, dry, tablet', 'Palladium on alumina, extent of labeling: 0.5 wt. % loading, spheres', 'Palladium on barium sulfate, extent of labeling:  5 wt% loading unreduced', 'Palladium on barium sulfate, extent of labeling: 5 wt. % loading, unreduced', 'Palladium on barium sulfate, reduced, extent of labeling: 5 wt. % loading', 'Palladium on carbon, extent of labeling: 1 wt. % loading, 4-8 mesh', 'Palladium, foil, 100x100mm, thickness 0.125mm, as rolled, 99.95%', 'Palladium, foil, 10mm disks, thickness 0.025mm, as rolled, 99.95%', 'Palladium, foil, 10mm disks, thickness 0.025mm, as rolled, 99.99+%', 'Palladium, foil, 10mm disks, thickness 0.02mm, as rolled, 99.95%', 'Palladium, foil, 10mm disks, thickness 0.03mm, as rolled, 99.95%', 'Palladium, foil, 10mm disks, thickness 0.047mm, as rolled, 99.95%', 'Palladium, foil, 10mm disks, thickness 0.075mm, as rolled, 99.95%', 'Palladium, foil, 10mm disks, thickness 0.125mm, as rolled, 99.95%', 'Palladium, foil, 10mm disks, thickness 0.25mm, as rolled, 99.95%', 'Palladium, foil, 10mm disks, thickness 0.25mm, as rolled, 99.99+%', 'Palladium, foil, 10mm disks, thickness 0.50mm, as rolled, 99.95%', 'Palladium, foil, 15mm disks, thickness 0.025mm, as rolled, 99.95%', 'Palladium, foil, 15mm disks, thickness 0.025mm, as rolled, 99.99+%', 'Palladium, foil, 15mm disks, thickness 0.02mm, as rolled, 99.95%', 'Palladium, foil, 15mm disks, thickness 0.03mm, as rolled, 99.95%', 'Palladium, foil, 15mm disks, thickness 0.047mm, as rolled, 99.95%', 'Palladium, foil, 15mm disks, thickness 0.075mm, as rolled, 99.95%', 'Palladium, foil, 15mm disks, thickness 0.125mm, as rolled, 99.95%', 'Palladium, foil, 25mm disks, thickness 0.025mm, as rolled, 99.95%', 'Palladium, foil, 25mm disks, thickness 0.025mm, as rolled, 99.99+%', 'Palladium, foil, 25mm disks, thickness 0.02mm, as rolled, 99.95%', 'Palladium, foil, 25mm disks, thickness 0.03mm, as rolled, 99.95%', 'Palladium, foil, 4mm disks, thickness 0.025mm, as rolled, 99.95%', 'Palladium, foil, 4mm disks, thickness 0.025mm, as rolled, 99.99+%', 'Palladium, foil, 4mm disks, thickness 0.047mm, as rolled, 99.95%', 'Palladium, foil, 4mm disks, thickness 0.075mm, as rolled, 99.95%', 'Palladium, foil, 4mm disks, thickness 0.125mm, as rolled, 99.95%', 'Palladium, foil, 4mm disks, thickness 0.25mm, as rolled, 99.99+%', 'Palladium, foil, 6mm disks, thickness 0.025mm, as rolled, 99.95%', 'Palladium, foil, 6mm disks, thickness 0.025mm, as rolled, 99.99+%', 'Palladium, foil, 6mm disks, thickness 0.047mm, as rolled, 99.95%', 'Palladium, foil, 6mm disks, thickness 0.075mm, as rolled, 99.95%', 'Palladium, foil, 6mm disks, thickness 0.125mm, as rolled, 99.95%', 'Palladium, foil, 6mm disks, thickness 0.25mm, as rolled, 99.99+%', 'Palladium, foil, 8mm disks, thickness 0.025mm, as rolled, 99.95%', 'Palladium, foil, 8mm disks, thickness 0.025mm, as rolled, 99.99+%', 'Palladium, foil, 8mm disks, thickness 0.047mm, as rolled, 99.95%', 'Palladium, foil, 8mm disks, thickness 0.075mm, as rolled, 99.95%', 'Palladium, foil, 8mm disks, thickness 0.125mm, as rolled, 99.95%', 'Palladium, foil, 8mm disks, thickness 0.25mm, as rolled, 99.99+%', 'Palladium, foil, light tested, 25x25mm, thickness 0.004mm, 99.95%', 'Palladium, foil, light tested, 25x25mm, thickness 0.006mm, 99.95%', 'Palladium, foil, not light tested, 25x25mm, thickness 0.0005mm, 99.75%', 'Palladium, foil, not light tested, 25x25mm, thickness 0.0015mm, 99.95%', 'Palladium, foil, not light tested, 25x25mm, thickness 0.0025mm, 99.95%', 'Palladium, foil, not light tested, 25x25mm, thickness 0.002mm, 99.95%', 'Palladium, foil, not light tested, 25x25mm, thickness 0.003mm, 99.95%', 'Palladium, foil, not light tested, 25x25mm, thickness 0.004mm, 99.95%', 'Palladium, foil, not light tested, 25x25mm, thickness 0.005mm, 99.95%', 'Palladium, foil, not light tested, 25x25mm, thickness 0.006mm, 99.95%', 'Palladium, foil, not light tested, 25x25mm, thickness 0.0125mm, 99.95%', 'Palladium, foil, not light tested, 50x50mm, thickness 0.0005mm, 99.75%', 'Palladium, foil, not light tested, 50x50mm, thickness 0.0025mm, 99.95%', 'Palladium, foil, not light tested, 50x50mm, thickness 0.002mm, 99.95%', 'Palladium, foil, not light tested, 50x50mm, thickness 0.003mm, 99.95%', 'Palladium, foil, not light tested, 50x50mm, thickness 0.004mm, 99.95%', 'Palladium, foil, not light tested, 50x50mm, thickness 0.005mm, 99.95%', 'Palladium, foil, not light tested, 50x50mm, thickness 0.006mm, 99.95%', 'Palladium, foil, not light tested, 50x50mm, thickness 0.008mm, 99.95%', 'Palladium, foil, not light tested, 50x50mm, thickness 0.0125mm, 99.95%', 'Palladium, foil, thickness 0.1 mm, length 0.05 m, coil width 2 mm', 'Palladium, foil, thickness 0.60 mm, 10 mm diameter, purity 99.95%', 'Palladium, foil, thickness 0.60 mm, size 10 x 10 mm, purity 99.95%', 'Palladium, foil, thickness 0.60 mm, size 25 x 25 mm, purity 99.95%', 'Palladium, powder, max. particle size 3 micron, weight 5 g, purity 99.95%', 'Palladium on alumina extent of labeling: 10 wt. % loading, powder, reduced, dry', 'Palladium on alumina, extent of labeling: 0.5 wt. % loading, 3.2 mm, pellets', 'Palladium on alumina, extent of labeling: 10 wt. % loading, powder, reduced, dry', 'Palladium on carbon, extent of labeling: 10 wt. % loading, matrix carbon, dry support', 'Palladium on carbon, extent of labeling: 5 wt. % loading, matrix carbon powder, wet support', 'Palladium, 0.5% on titanium silicate, 50% water-wet paste (NanoSelect LF 200)', 'Palladium, evaporation slug, diam. x L 0.6 cm x 0.6 cm, 99.95% trace metals basis', 'Palladium, evaporation slug, diam. x L 0.9 cm x 1.2 cm, 99.95% trace metals basis', 'Palladium, foil, 0.1m coil, thickness 0.1mm, coil width 2mm, as rolled, 99.95%', 'Palladium, foil, 0.2m coil, thickness 0.1mm, coil width 2mm, as rolled, 99.95%', 'Palladium, foil, 0.5m coil, thickness 0.1mm, coil width 2mm, as rolled, 99.95%', 'Palladium, foil, 1m coil, thickness 0.1mm, coil width 2mm, as rolled, 99.95%', 'Palladium, foil, light tested, 100x100mm, thickness 0.025mm, as rolled, 99.95%', 'Palladium, foil, light tested, 100x100mm, thickness 0.025mm, as rolled, 99.99+%', 'Palladium, foil, light tested, 100x100mm, thickness 0.047mm, as rolled, 99.95%', 'Palladium, foil, light tested, 100x100mm, thickness 0.075mm, as rolled, 99.95%', 'Palladium, foil, light tested, 25x25mm, thickness 0.025mm, as rolled, 99.95%', 'Palladium, foil, light tested, 25x25mm, thickness 0.025mm, as rolled, 99.99+%', 'Palladium, foil, light tested, 25x25mm, thickness 0.03mm, as rolled, 99.95%', 'Palladium, foil, light tested, 25x25mm, thickness 0.047mm, as rolled, 99.95%', 'Palladium, foil, light tested, 25x25mm, thickness 0.075mm, as rolled, 99.95%', 'Palladium, foil, light tested, 50x50mm, thickness 0.025mm, as rolled, 99.99+%', 'Palladium, foil, light tested, 50x50mm, thickness 0.03mm, as rolled, 99.95%', 'Palladium, foil, light tested, 50x50mm, thickness 0.047mm, as rolled, 99.95%', 'Palladium, foil, light tested, 50x50mm, thickness 0.075mm, as rolled, 99.95%', 'Palladium, foil, not light tested, 100x100mm, thickness 0.004mm, 99.95%', 'Palladium, foil, not light tested, 100x100mm, thickness 0.005mm, 99.95%', 'Palladium, foil, not light tested, 100x100mm, thickness 0.006mm, 99.95%', 'Palladium, foil, not light tested, 100x100mm, thickness 0.008mm, 99.95%', 'Palladium, foil, not light tested, 100x100mm, thickness 0.0125mm, 99.95%', 'Palladium, foil, not light tested, 100x100mm, thickness 0.025mm, as rolled, 99.95%', 'Palladium, foil, not light tested, 100x100mm, thickness 0.025mm, as rolled, 99.99+%', 'Palladium, foil, not light tested, 100x100mm, thickness 0.02mm, as rolled, 99.95%', 'Palladium, foil, not light tested, 100x100mm, thickness 0.03mm, as rolled, 99.95%', 'Palladium, foil, not light tested, 150x150mm, thickness 0.008mm, 99.95%', 'Palladium, foil, not light tested, 150x150mm, thickness 0.0125mm, 99.95%', 'Palladium, foil, not light tested, 150x150mm, thickness 0.025mm, as rolled, 99.95%', 'Palladium, foil, not light tested, 150x150mm, thickness 0.02mm, as rolled, 99.95%', 'Palladium, foil, not light tested, 150x150mm, thickness 0.03mm, as rolled, 99.95%', 'Palladium, foil, not light tested, 25x25mm, thickness 0.025mm, as rolled, 99.99+%', 'Palladium, foil, not light tested, 25x25mm, thickness 0.02mm, as rolled, 99.95%', 'Palladium, foil, not light tested, 25x25mm, thickness 0.03mm, as rolled, 99.95%', 'Palladium, foil, not light tested, 50x50mm, thickness 0.025mm, as rolled, 99.95%', 'Palladium, foil, not light tested, 50x50mm, thickness 0.025mm, as rolled, 99.99+%', 'Palladium, foil, not light tested, 50x50mm, thickness 0.02mm, as rolled, 99.95%', 'Palladium, foil, not light tested, 50x50mm, thickness 0.03mm, as rolled, 99.95%', 'Palladium, powder, 3 max. part. size (micron), weight 1 g, purity 99.95%', 'Palladium, powder, 3 max. part. size (micron), weight 2 g, purity 99.95%', 'Palladium, powder, max. particle size 10 micron, weight 1 g, purity 99.95%', 'Palladium, powder, max. particle size 10 micron, weight 2 g, purity 99.95%', 'Palladium, powder, max. particle size 10 micron, weight 5 g, purity 99.95%', 'Palladium, powder, max. particle size 150 micron, weight 1 g, purity 99.95%', 'Palladium, powder, max. particle size 150 micron, weight 2 g, purity 99.95%', 'Palladium, powder, max. particle size 150 micron, weight 5 g, purity 99.95%', 'Palladium, tube, outside diameter 6.6 mm, length 100 mm, wall thickness 0.125 mm', 'Palladium, tube, outside diameter 6.6 mm, length 200 mm, wall thickness 0.125 mm', 'Palladium, tube, outside diameter 6.6 mm, length 50 mm, wall thickness 0.125 mm', 'Palladium on alumina extent of labeling: 5 wt. % loading (dry basis), powder, wet support <=50% water', 'Palladium on carbon, extent of labeling: 10 wt. % loading (dry basis), matrix carbon powder, wet support', 'Palladium on carbon, extent of labeling: 5 wt. % loading (dry basis), matrix carbon, wet support', 'Palladium single crystal disc, 10mm (0.39in) dia, 1-2mm (0.04-0.08in) thick, (111) orientation, +/-0.5 degrees', 'Palladium single crystal, 9-10mm (0.35-0.39in) dia, 50mm (2.0in) long, (100) orientation, +/-2 degrees', 'Palladium single crystal, 9-10mm (0.35-0.39in) dia, 50mm (2.0in) long, (110) orientation, +/-2 degrees', 'Palladium single crystal, 9-10mm (0.35-0.39in) dia, 50mm (2.0in) long, (111) orientation, +/-2 degrees', 'Palladium single crystal, 9-10mm (0.35-0.39in) dia, 50mm (2.0in) long, random orientation', 'Palladium, 10% on activated carbon powder, eggshell, unreduced, Type 10R394, nominally 50% water wet', 'Palladium, microfoil, disks, 10mm, thinness 0.05mum, specific density 63.6mug/cm2, permanent mylar 3.5mum support, 99.99%', 'Palladium, microfoil, disks, 10mm, thinness 0.1mum, specific density 119.2mug/cm2, permanent mylar 3.5mum support, 99.99%', 'Palladium, microfoil, disks, 10mm, thinness 0.25mum, specific density 303.4mug/cm2, permanent mylar 3.5mum support, 99.99%', 'Palladium, microfoil, disks, 10mm, thinness 0.5mum, specific density 303.4mug/cm2, permanent mylar 3.5mum support, 99.99%', 'Palladium, microfoil, disks, 25mm, thinness 0.05mum, specific density 63.6mug/cm2, permanent mylar 3.5mum support, 99.99%', 'Palladium, microfoil, disks, 25mm, thinness 0.1mum, specific density 119.2mug/cm2, permanent mylar 3.5mum support, 99.99%', 'Palladium, microfoil, disks, 25mm, thinness 0.25mum, specific density 303.4mug/cm2, permanent mylar 3.5mum support, 99.99%', 'Palladium, microfoil, disks, 25mm, thinness 0.5mum, specific density 303.4mug/cm2, permanent mylar 3.5mum support, 99.99%', 'Palladium, microfoil, disks, 50mm, thinness 0.05mum, specific density 63.6mug/cm2, permanent mylar 3.5mum support, 99.99%', 'Palladium, microfoil, disks, 50mm, thinness 0.1mum, specific density 119.2mug/cm2, permanent mylar 3.5mum support, 99.99%', 'Palladium, microfoil, disks, 50mm, thinness 0.25mum, specific density 303.4mug/cm2, permanent mylar 3.5mum support, 99.99%', 'Palladium, tube, 100mm, outside diameter 2.0mm, inside diameter 1.6mm, wall thickness 0.2mm, as drawn, 99.95%', 'Palladium, tube, 120mm, outside diameter 6mm, inside diameter 5mm, wall thickness 0.5mm, as drawn, 99.95%', 'Palladium, tube, 200mm, outside diameter 2.0mm, inside diameter 1.6mm, wall thickness 0.2mm, as drawn, 99.95%', 'Palladium, tube, 50mm, outside diameter 1.0mm, inside diameter 0.8mm, wall thickness 0.1mm, as drawn, 99.95%', 'Palladium, tube, 50mm, outside diameter 2.0mm, inside diameter 1.6mm, wall thickness 0.2mm, as drawn, 99.95%']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Zebularine","PubChemCID":"100016","SMILES":"C1=CN(C(=O)N=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O","Synonyms":"['Zebularine', '3690-10-6', '4-Deoxyuridine', 'Pyrimidin-2-one ribonucleoside', 'Pyrimidin-2-one beta-ribofuranoside', 'Pyrimidin-2-one beta-D-ribofuranoside', 'CHEBI:46938', '1-beta-D-ribofuranosyl-2(1H)-pyrimidinone', '1-beta-D-ribofuranosylpyrimidin-2(1H)-one', '7A9Y5SX0GY', '2(1H)-Pyrimidinone, 1-beta-D-ribofuranosyl-', '1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one', 'NSC-309132', 'URIDINE, 4-DEOXY-', '2-Pyrimidone-1-beta-D-riboside', 'NSC309132', 'PYRIMIDIN-2-ONE .BETA.-D-RIBOFURANOSIDE', '1-(.BETA.-D-RIBOFURANOSYL)-2-PYRIMIDONE', '2(1H)-Pyrimidinone, 1-.beta.-D-ribofuranosyl-', '1-.BETA.-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE', '1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-1,2-dihydropyrimidin-2-one', '1-(beta-d-ribofuranosyl)-2-pyrimidone', 'MFCD04973699', '1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one', 'NSC309132;4-Deoxyuridine', '1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one', 'NSC 309132', '4pd7', 'UNII-7A9Y5SX0GY', 'SCHEMBL13032', 'pyrimidin-2-one-ribonucleoside', 'CHEMBL504567', 'GTPL4729', 'DTXSID20958099', 'RPQZTTQVRYEKCR-WCTZXXKLSA-N', 'GLXC-06602', 'HMS3413C14', 'HMS3677C14', 'BDBM50226311', 'HB1378', '1-Pentofuranosylpyrimidin-2(1H)-one', \"4-Deoxy-3'-deoxy-3'-fluoro uridine\", 'AKOS024457033', 'Zebularine, >=98% (HPLC), solid', 'CS-3403', 'DB03068', '1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-Hydroxymethyl-Tetrahydro-Furan-2-yl)-1H-Pyrimidin-2-one', 'NCGC00159549-02', 'BP-58607', 'DA-59262', 'DHZ', 'DS-11855', 'HY-13420', 'NS00011709', '1-(beta-D-ribofuranosyl)pyrimidin-2(1H)-one', '1-(?-D-Ribofuranosyl)-1,2-dihydropyrimidin-2-one', 'Q8068322', '1-(beta-D-Ribofuranosyl)-1,2-dihydropyrimidin-2-one', 'BRD-K87714311-001-01-9', 'BRD-K87714311-001-02-7', 'ZE8']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Compound e","PubChemCID":"11306390","SMILES":"C[C@@H](C(=O)N[C@@H]1C(=O)N(C2=CC=CC=C2C(=N1)C3=CC=CC=C3)C)NC(=O)CC4=CC(=CC(=C4)F)F","Synonyms":"['Compound E', 'gamma-Secretase Inhibitor XXI', 'CHEBI:101713', 'N(2)-[(3,5-difluorophenyl)acetyl]-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-L-alaninamide', 'N(2)-((3,5-difluorophenyl)acetyl)-N-((3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)-L-alaninamide', '209986-17-4', 'GSI-XXI', '(S)-2-(2-(3,5-difluorophenyl)acetamido)-N-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanamide', '(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]-N-[(3S)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]propanamide', '(s,s)-2-[2-(3,5-difluorophenyl)-acetylamino]-n-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1h-benzo[e][1,4]diazepin-3-yl)-propionamide', 'Compound E (secretase inhibitor)', 'CompoundE', '(2S)-2-{[(3,5-Difluorophenyl)acetyl]amino}-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide', 'N2-[(3,5-difluorophenyl)acetyl]-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-L-alaninamide', 'SCHEMBL453584', 'W6YYB9B856', 'CHEMBL1091498', 'DTXSID0042666', 'C27H24F2N4O3', 'CHEBI:131161', 'GLXC-02107', 'EX-A3838', 'HB3849', 'ZB1617', 'AKOS037435223', 'BS-15830', 'FD103782', 'HY-14176', 'N-[(1S)-2-[[(3S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide', 'gamma-Secretase Inhibitor XXI, Compound E', 'Compound E (gamma-Secretase Inhibitor XXI)', 'CS-0003250', 'E98743', '(2S)-2-[2-(3,5-difluorophenyl)acetamido]-N-[(3S)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]propanamide', 'Benzeneacetamide, N-[(1S)-2-[[(3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-', 'N-[(1S)-2-[[(3S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetam  ide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"GDC0941","PubChemCID":"17755052","SMILES":"CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6","Synonyms":"['957054-30-7', 'GDC-0941', 'PICTILISIB', 'Pictrelisib', 'GDC0941', 'GDC 0941', '4-(2-(1H-Indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine', '2-(1H-Indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine', 'GDC-0941 (Pictilisib)', 'Pictilisib (GDC-0941)', 'ICY00EMP8P', 'Thieno[3,2-d]pyrimidine, 2-(1H-indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-', 'CHEBI:65326', 'CDC-0941', '957054-30-7 (free base)', '2-(1H-Indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)thieno[3,2-d]pyrimidine', '4-[2-(1H-indazol-4-yl)-6-[(4-methylsulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine', '957054-50-1', '2-(1H-indazol-4-yl)-6-((4-(methanesulfonyl)piperazin-1-yl)methyl)-4-(morpholin-4-yl)thieno(3,2-d)pyrimidine', '4-(2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno(3,2-d)pyrimidin-4-yl)morpholine', '2-(1H-indazol-4-yl)-6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-(morpholin-4-yl)thieno[3,2-d]pyrimidine', '2-(1h-Indazol-4-Yl)-6-{[4-(Methylsulfonyl)piperazin-1-Yl]methyl}-4-Morpholin-4-Yl-Thieno[3,2-D]pyrimidine', 'GD9', 'Thieno(3,2-d)pyrimidine, 2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)-1-piperazinyl]methyl)-4-(4-morpholinyl)-', 'RG-7321', 'Pictilisib [USAN:INN]', 'UNII-ICY00EMP8P', 'C23H27N7O3S2', 'THIENO(3,2-D)PYRIMIDINE, 2-(1H-INDAZOL-4-YL)-6-((4-(METHYLSULFONYL)-1-PIPERAZINYL)METHYL)-4-(4-MORPHOLINYL)-', 'MFCD11616196', 'Kinome_3719', 'PICTILISIB [MI]', 'GDC0941(Pictilisib)', 'PICTILISIB [INN]', 'Pictilisib (USAN/INN)', 'PICTILISIB [USAN]', 'GDC0941(Pictilisib)?', 'Pictilisib; GDC-0941', 'PICTILISIB [WHO-DD]', 'MLS006010057', 'SCHEMBL190812', 'CHEMBL521851', 'GTPL5682', 'BDBM25028', 'DTXSID40241930', 'EX-A167', 'LHNIIDJUOCFXAP-UHFFFAOYSA-N', 'HMS2043A16', 'HMS3244H06', 'HMS3244H10', 'HMS3244H14', 'HMS3265I05', 'HMS3265I06', 'HMS3265J05', 'HMS3265J06', 'HMS3654K13', 'HMS3744A19', 'BCP01714', 'EX-A1536', 'GNE 0941', 'NSC755385', 'NSC800852', 'RG7321', 's1065', 'AKOS015966503', 'BCP9000715', 'CCG-264801', 'CS-0081', 'DB11663', 'FI32904', 'NSC-755385', 'NSC-800852', 'SB19941', 'SDCCGSBI-0654334.P001', 'NCGC00187482-01', 'NCGC00187482-03', 'NCGC00187482-10', '2-(1H-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine', 'AC-32623', 'AS-19377', 'HY-50094', 'SMR004701219', 'NS00071518', 'SW202556-4', 'D10189', 'A845396', 'Pictilisib (GDC0941, RG7321, GNE0941))', 'BRD-K52911425-001-02-3', 'BRD-K52911425-001-09-8', 'Q27088388', '2-(1H-Indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidine;Pictilisib', '2-(1H-indazol-4-yl)-6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-ylthieno[3,2-d]pyrimidine', '4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine', '4-[2-(1H-indazol-4-yl)-6-[(4-methylsulfonyl-1-piperazinyl)methyl]-4-thieno[3,2-d]pyrimidinyl]morpholine', '4-{6-[(4-methanesulfonylpiperazin-1-yl)methyl]-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl}-2H-indazole']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Ripasudil","PubChemCID":"9863672","SMILES":"C[C@H]1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)F","Synonyms":"['Ripasudil', '223645-67-8', 'Ripasudil [INN]', '4-fluoro-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline', 'UNII-11978226XX', 'RIPASUDIL [MI]', 'RIPASUDIL [WHO-DD]', '11978226XX', 'K-115 (ripasudil hydrochloride dihydrate)', '1H-1,4-Diazepine, 1-((4-fluoro-5-isoquinolinyl)sulfonyl)hexahydro-2-methyl-, (2S)-', 'Isoquinoline, 4-fluoro-5-(((2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl)sulfonyl)-', 'ripasudilum', '4-fluoro-5-(((2S)-2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline', '4-fluoro-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline', '1H-1,4-Diazepine, 1-[(4-fluoro-5-isoquinolinyl)sulfonyl]hexahydro-2-methyl-, (2S)-', 'Isoquinoline, 4-fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-', 'glanatec', 'glanatec (tn)', 'k115 Free base', 'K-115 free base', 'Ripasudil free base', 'CHEMBL3426621', '(S)-4-Fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline', 'K 115 free base', 'Ripasudil (USAN/INN)', 'RIPASUDIL [USAN]', 'K-115 (free base)', 'K-115 anhydrous free base', 'K-321 anhydrous free base', 'SCHEMBL31542', 'GTPL10423', 'CHEBI:136046', 'DTXSID001025609', 'BCP11083', 'EX-A3647', 'BDBM50087135', 'HY-15685A', 'NSC800869', 'AKOS027338679', 'CS-3402', 'DB13165', 'NSC-800869', 'NCGC00496843-01', 'AC-36873', 'AS-35170', 'NS00069625', 'D13014', 'BRD-K53814070-310-01-3', 'Q21098890', '(S)-(-)-1-(4-fluoro-5-isoquinolinesulfonyl)-2-methyl-1,4-homopiperazine', '4-Fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]isoquinoline']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"AT13148","PubChemCID":"24905401","SMILES":"C1=CC(=CC=C1C2=CNN=C2)[C@@](CN)(C3=CC=C(C=C3)Cl)O","Synonyms":"['1056901-62-2', 'AT13148', 'AT-13148', '(S)-1-(4-(1H-Pyrazol-4-yl)phenyl)-2-amino-1-(4-chlorophenyl)ethanol', '(1S)-2-amino-1-(4-chlorophenyl)-1-[4-(1H-pyrazol-4-yl)phenyl]ethanol', 'UNII-A49037RP1E', 'A49037RP1E', '(+)-(S)-2-Amino-1-(4-chlorophenyl)-1-(4-(1H-pyrazol-4-yl)phenyl)ethanol', 'AT 13148', 'Benzenemethanol, alpha-(aminomethyl)-alpha-(4-chlorophenyl)-4-(1H-pyrazol-4-yl)-, (alphaS)-', 'MFCD25976789', 'RKD', 'SCHEMBL851471', 'CHEMBL3544960', 'GLXC-04834', 'BCP08961', 'EX-A1797', 'BDBM50242733', 'NSC771650', 'NSC799337', 's7563', 'AKOS024258899', 'CCG-267617', 'CS-3136', 'NSC-771650', 'NSC-799337', 'SB16880', 'NCGC00386423-03', 'AC-32943', 'AS-35164', 'FA137648', 'HY-16071', 'BRD-K32127727-001-01-8', 'BRD-K32127727-001-02-6', 'Q27273616', 'Z2685929061', '(S)-1-(4-(1H-pyrazol-4-yl)phenyl)-2-amino-1-(4-chlorophenyl)ethan-1-ol', '(s)-2-amino-1-(4-chloro-phenyl)-1-[4-(1h-pyrazol-4-yl)-phenyl]-ethanol', '(S)-1-(4-(1H-Pyrazol-4-yl)phenyl)-2-amino-1-(4-chlorophenyl)ethanol; SCHEMBL851471', 'BENZENEMETHANOL, .ALPHA.-(AMINOMETHYL)-.ALPHA.-(4-CHLOROPHENYL)-4-(1H-PYRAZOL-4-YL)-, (.ALPHA.S)-']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Pravastatin","PubChemCID":"54687","SMILES":"CC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)O)O)O)O","Synonyms":"['pravastatin', '81093-37-0', 'Pravastatina', 'Pravastatine', 'Pravastatinum', 'Eptastatin', 'Pravator', 'Pravastatinum [Latin]', 'CCRIS 7557', 'UNII-KXO2KT9N0G', 'KXO2KT9N0G', 'CHEBI:63618', 'C10AA03', '(3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid', 'DTXSID6023498', 'HSDB 8368', 'Pravastatinum (Latin)', '1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-((2S)-2-methyl-1-oxobutoxy)-, (betaR,deltaR,1S,2S,6S,8S,8aR)-', '1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, (1S-(1alpha(betas*,deltas*),2alpha,6alpha,8beta(R*),8aalpha))-', '(+)-(3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(S)-2-methylbutyryl]oxy}-1,2,6,7,8,8a-hexahydro-1-naphthyl]heptanoic acid', '(+)-(3R,5R)-3,5-dihydroxy-7-((1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-(((S)-2-methylbutyryl)oxy)-1,2,6,7,8,8a-hexahydro-1-naphthyl)heptanoic acid', '(3R,5R)-3,5-dihydroxy-7-((1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-(((2S)-2-methylbutanoyl)oxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)heptanoic acid', 'DTXCID003498', '(1S-(1alpha(betaS*,deltaS*),2alpha,6alpha,8beta(R*),8aalpha))-1,2,6,7,8,8a-Hexahydro-beta,!d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic Acid', 'Pravachol', 'Pravastatin acid', '(3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid', 'Pravastatin (INN)', 'CHEMBL1144', 'Pravastatine [French]', 'Pravastatina [Spanish]', '(3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid', '(betaR,deltaR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-beta,delta,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid', 'PRAVASTATIN [INN]', 'Pravastatin [INN:BAN]', 'Mevalothin', 'Pravator (TN)', '(3R,5R)-3,5-Dihydroxy-7-((1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-(((S)-2-methylbutanoyl)oxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)heptanoic acid', 'Pravastatin-3H', '3beta-Hydroxycompactin', 'KS-5015', 'PRAVASTATIN [VANDF]', 'SCHEMBL1117', 'PRAVASTATIN [WHO-DD]', 'BIDD:GT0773', 'PRAVASTATIN [EMA EPAR]', 'GTPL2953', 'BDBM20688', 'TUZYXOIXSAXUGO-PZAWKZKUSA-N', 'HMS3715P11', 'HY-B0165', 'LMFA05000695', 's5713', 'AKOS015895229', 'CCG-221195', 'DB00175', 'NCGC00188962-01', 'NCGC00188962-02', '1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, (1S-(1alpha(betaS*,deltaS*),2alpha,6alpha,8beta(R*),8aalpha))-1-Naphthaleneheptanoic acid', 'FP158560', 'NS00000420', 'C01844', 'D08410', 'H12037', 'EN300-6481366', 'SR-01000781259', 'Q1240093', 'SR-01000781259-2', 'BRD-K60511616-236-01-4', 'BRD-K60511616-236-02-2', 'BRD-K60511616-236-06-3', 'BRD-K60511616-236-08-9', '(|AR,|AR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-|A,|A,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid', '1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-.beta.,.delta.,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-, (.beta.R,.delta,R,1S,2S,6S,8S,8aR)-']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Amuvatinib","PubChemCID":"11282283","SMILES":"C1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6","Synonyms":"['Amuvatinib', '850879-09-3', 'MP470', 'MP-470', 'MP 470', 'HPK56', 'HPK 56', 'HPK-56', 'Amuvatinib [USAN]', 'Amuvatinib [USAN:INN]', 'SO9S6QZB4R', 'AMUVATINIB [INN]', 'AMUVATINIB [WHO-DD]', 'DTXSID50234176', '1-Piperazinecarbothioamide, N-(1,3-benzodioxol-5-ylmethyl)-4-benzofuro(3,2-d)pyrimidin-4-yl-', 'N-(1,3-benzodioxol-5-ylmethyl)-4-([1]benzoxolo[2,3-e]pyrimidin-4-yl)piperazine-1-carbothioamide', 'N-(1,3-BENZODIOXOL-5-YLMETHYL)-4-(1)BENZOFURO(3,2-D)PYRIMIDIN-4-YLPIPERAZINE-1-CARBOTHIOAMIDE', 'amuvatinibum', '1-Piperazinecarbothioamide, N-(1,3-benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-', '4-(1)Benzofuro(3,2-D)Pyrimidin-4-Yl-N-(1,3-Benzodioxol-5-Ylmethyl)Piperazine-1-Carbothioamide', '4-[1]Benzofuro[3,2-D]Pyrimidin-4-Yl-N-(1,3-Benzodioxol-5-Ylmethyl)Piperazine-1-Carbothioamide', 'N-((2H-1,3-benzodioxol-5-yl)methyl)-4-(8-oxa-3,5-diazatricyclo(7.4.0.0^(2,7))trideca-1(9),2(7),3,5,10,12-hexaen-6-yl)piperazine-1-carbothioamide', 'N-(1,3-benzodioxol-5-ylmethyl)-4-((1)benzoxolo(2,3-e)pyrimidin-4-yl)piperazine-1-carbothioamide', 'N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-{8-oxa-3,5-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaen-6-yl}piperazine-1-carbothioamide', 'DTXCID50156667', 'Receptor Tyrosine Kinase Inhibitor MP470', 'N-(1,3-Benzodioxol-5-ylmethyl)-4-(benzofuro(3,2-d)pyrimidin-4-yl)piperazine-1-carbothioamide', 'Amuvatinib (MP-470)', 'N-(1,3-benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide', 'N-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide', 'N-(Benzo[d][1,3]dioxol-5-ylmethyl)-4-(benzofuro-[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide', 'N-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide.', 'UNII-SO9S6QZB4R', 'MFCD16038298', 'Amuvatinib(MP470)', 'Amuvatinib (USAN/INN)', 'Amuvatinib (MP-470)?', 'SCHEMBL93976', 'MLS006010954', 'GTPL7932', 'CHEMBL2103851', 'CHEBI:91389', 'EX-A236', 'FOFDIMHVKGYHRU-UHFFFAOYSA-N', 'BCPP000157', 'GLXC-06451', 'HMS3244A11', 'HMS3244A12', 'HMS3244B11', 'HMS3295E01', 'HMS3654D07', 'MP-470 (RAD51)', 'BDBM50172081', 'NSC754349', 'NSC799332', 's1244', 'AKOS025149102', 'BCP9000965', 'CCG-264877', 'CS-0178', 'DB12742', 'NSC-754349', 'NSC-799332', 'SB19384', 'SDCCGSBI-0654361.P001', 'NCGC00263158-01', 'NCGC00263158-05', 'NCGC00263158-07', 'AC-32058', 'AS-16213', 'HY-10206', 'N-(1,3-Benzodioxol-5-ylmethyl)-4-(benzofuro(3,2-d)pyrimidin-4-yl)piperazine-1- carbothioamide', 'SMR004702758', 'NS00072135', 'SW219808-1', 'D09864', 'EN300-7401591', 'BRD-K66538826-001-01-5', 'BRD-K66538826-001-07-2', 'Q27074458', '4-Benzo[4,5]furo[3,2-d]pyrimidin-4-yl-piperazine-1-carbothioic acid (benzo[1,3]-dioxol-5-ylmethyl)-amide', '4-Benzo[4,5]furo[3,2-d]pyrimidin-4-yl-piperazine-1-carbothioic acid (benzo[1,3]dioxol-5-ylmethyl)-amide', '4-Benzo[4,5]furo[3,2-d]pyrimidin-4-yl-piperazine-1-carbothioic acid(benzo[1,3]dioxol-5-ylmethyl)-amide', '4-Benzo[4.5]furo[3.2-d]pyrimidin-4-yl-piperazine-1-carbothioic acid (benzo[1.3]dioxol-5-ylmethyl)-amide', 'N-[(1,3-dioxaindan-5-yl)methyl]-4-{8-oxa-3,5-diazatricyclo[7.4.0.0,2,7]trideca-1(9),2,4,6,10,12-hexaen-6-yl}piperazine-1-carbothioamide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Erlotinib","PubChemCID":"176870","SMILES":"COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC","Synonyms":"['Erlotinib', '183321-74-6', 'N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine', '4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-', 'erlotinibum', 'N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine', 'UNII-J4T82NDH7E', 'J4T82NDH7E', 'DTXSID8046454', 'HSDB 8082', 'OSI 744', 'CHEBI:114785', 'RG-1415', '[6,7-BIS(2-METHOXY-ETHOXY)QUINAZOLINE-4-YL]-(3-ETHYNYLPHENYL)AMINE', 'DTXCID6026454', 'CP-35877401', 'R 1415', 'R-1415', '[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine', '(6,7-bis(2-methoxy-ethoxy)quinazoline-4-yl)-(3-ethynylphenyl)amine', '(6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl)-(3-ethynyl-phenyl)-amine', 'L01XE03', 'Tarceva', '4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline', 'Erlotinib free base', 'Erlotinib Base', 'OSI-774', 'Erlotinib [INN]', 'Erlotinib, Free Base', 'CP-358,774', '183321-74-6 (free base)', 'MFCD02089651', 'CHEMBL553', 'CP-358774', 'NSC 718781', 'Erlotinib (INN)', 'NCGC00164574-01', 'Erlotinib(Tarceva)', '1429636-49-6', 'CAS-183321-74-6', 'Erlotinib [INN:BAN]', 'SR-05000001460', 'CP358774', 'Erotinib', 'nchembio866-comp3', 'Erlotinib free base?', 'Erlotinib (Standard)', 'Kinome_3317', 'ERLOTINIB [MI]', 'ERLOTINIB [VANDF]', 'ERLOTINIB [WHO-DD]', 'SCHEMBL8413', 'ERLOTINIB [EMA EPAR]', 'BDBM5446', 'cid_176870', 'GTPL4920', 'AAKJLRGGTJKAMG-UHFFFAOYSA-N', 'HMS2089F05', 'HMS3244M19', 'HMS3244M20', 'HMS3244N19', 'HMS3295A19', 'HMS3713C22', 'HMS3745M05', 'Tox21_112202', 'AC-399', 'HY-50896R', 'NSC800097', 's7786', 'STK623143', 'AKOS000282911', 'Tox21_112202_1', 'CCG-220420', 'CS-0620', 'DB00530', 'NSC-800097', 'Ro-508231', 'SB16916', 'SDCCGSBI-0634409.P005', 'NCGC00164574-03', 'NCGC00164574-05', 'NCGC00164574-06', 'NCGC00164574-14', 'NCGC00164574-25', 'AS-35132', 'BCB03_000783', 'BE164419', 'HY-50896', 'SY028059', 'NS00006169', 'D07907', 'EN300-708808', 'K00241', 'AB01273955-01', 'AB01273955-02', 'AB01273955-03', 'Q418369', 'SR-05000001460-1', 'SR-05000001460-2', 'SR-05000001460-3', 'SR-05000001460-6', 'BRD-K70401845-001-15-7', 'BRD-K70401845-003-04-7', 'BRD-K70401845-003-09-6', 'Z2588038919', '4-[(3-Ethynylphenyl)amino]-6,7-bis(2-methoxyethoxy)quinazoline; N-(3-Ethynylphenyl)[6,7-bis(2-methoxyethoxy)quinazolin-4-yl]amine; Tarceva']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"AZD6482","PubChemCID":"44137675","SMILES":"CC1=CN2C(=O)C=C(N=C2C(=C1)[C@@H](C)NC3=CC=CC=C3C(=O)O)N4CCOCC4","Synonyms":"['AZD6482', 'AZD-6482', '2-[[(1R)-1-(7-methyl-2-morpholin-4-yl-4-oxopyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoic acid', '78G6MP5PZ5', '2-[[(1R)-1-[7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid', 'UNII-78G6MP5PZ5', 'DTXSID00657619', '2-(((1R)-1-(7-Methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido(1,2-a)pyrimidin-9-yl)ethyl)amino)benzoic acid', '2-({(1R)-1-[7-Methyl-2-(morpholin-4-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl}amino)benzoic acid', '2-{[(1R)-1-[7-methyl-2-(morpholin-4-yl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino}benzoic acid', '2-(((1R)-1-(7-Methyl-2-(morpholin-4-yl)-4-oxo-4H-pyrido(1,2-a)pyrimidin-9-yl)ethyl)amino)benzoic acid', '2-(((1R)-1-(7-methyl-2-morpholin-4-yl-4-oxopyrido(1,2-a)pyrimidin-9-yl)ethyl)amino)benzoic acid', 'DTXCID60608369', '1173900-33-8', 'AZD 6482', '(R)-2-(1-(7-methyl-2-morpholino-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethylamino)benzoic acid', 'CHEMBL2165191', '2-{[(1R)-1-[7-methyl-2-(morpholin-4-yl)-4-oxopyrido[1,2-a]pyrimidin-9-yl]ethyl]amino}benzoic acid', 'Benzoic acid, 2-[[(1R)-1-[7-methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]-', 'AZD 6482 [WHO-DD]', '(R)-2-((1-(7-Methyl-2-morpholino-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethyl)amino)benzoic acid', '4urk', 'IRTDIKMSKMREGO-OAHLLOKOSA-N', 'MFCD16659062', '2-[[(1r)-1-(7-Methyl-2-Morpholin-4-Yl-4-Oxidanylidene-Pyrido[1,2-A]pyrimidin-9-Yl)ethyl]amino]benzoic Acid', 'MLS006010986', 'GTPL8059', 'SCHEMBL1812377', 'CHEBI:91359', 'KIN-193', 'AZD6482?', 'EX-A1807', 'BDBM50395821', 'NSC799349', 's1462', 'AKOS015935014', 'BCP9000355', 'CCG-268743', 'CS-0086', 'DB14980', 'NSC-799349', 'NCGC00263154-01', 'AC-32792', 'AS-74808', 'FA137652', 'HY-10344', 'SMR004702788', 'DB-336213', 'SW219187-1', 'BRD-K58772419-001-01-3', 'BRD-K58772419-001-07-0', 'BRD-K58772419-001-08-8', 'Q27074771', '(-) 2-{[(1R)-1-(7-Methyl-2-morpholin-4-yl-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethyl]amino}benzoic acid']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"KD025","PubChemCID":"11950170","SMILES":"CC(C)NC(=O)COC1=CC=CC(=C1)C2=NC3=CC=CC=C3C(=N2)NC4=CC5=C(C=C4)NN=C5","Synonyms":"['Belumosudil', 'SLx 2119', 'UNII-834YJF89WO', 'Slx-2119 free base', 'Rock2 inhibitor kd025', 'SLx2119', '834YJF89WO', 'Acetamide, 2-(3-(4-(1H-indazol-5-ylamino)-2-quinazolinyl)phenoxy)-N-(1-methylethyl)-', '2-[3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-acetamide', '2-(3-(4-(1H-indazol-5-ylamino)-2-quinazolinyl)phenoxy)-N-(1-methylethyl)-acetamide', 'ROCK-II Inhibitor KD025', 'Rho-associated Coiled-coil Kinase 2 Inhibitor KD025', '911417-87-3', 'SLx-2119', 'KD-025', 'KD025', '2-(3-(4-((1H-indazol-5-yl)amino)quinazolin-2-yl)phenoxy)-N-isopropylacetamide', 'KD025 (SLx-2119)', 'Rezurock', 'Belumosudil [USAN]', 'C26H24N6O2', 'MFCD23098791', '2-[3-[4-(1H-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide', '2-[3-[4-[(1H-Indazol-5-yl)amino]quinazolin-2-yl]phenoxy]-N-isopropylacetamide', 'KD 025', 'Belumosudil; KD 025', '2-(3-(4-(1H-indazol-5-ylamino)quinazolin-2-yl)phenoxy)-N-isopropylacetamide', '2-[3-[4-(1~{H}-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-~{N}-propan-2-yl-ethanamide', '2-{3-[4-(2H-indazol-5-ylamino)quinazolin-2-yl]phenoxy}-N-isopropylacetamide', 'Kinome_2597', 'BELUMOSUDIL [INN]', 'BELUMOSUDIL [WHO-DD]', 'SCHEMBL878202', 'GTPL9558', 'CHEMBL2005186', 'DTXSID80238425', 'GKHIVNAUVKXIIY-UHFFFAOYSA-N', 'BDBM322155', 'BDBM435505', 'BCP15921', 'EX-A2314', 'LLB41787', 's7936', 'WHO 11343', 'SLx-2119(KD-025)', 'SLx-2119; KD-025', 'US10570123, Example 232', 'AKOS027338708', 'CCG-269256', 'CS-0776', 'SB16915', 'SLx-2119(KD-025,Belumosudil )?', 'NCGC00378903-01', 'NCGC00378903-02', 'AC-33057', 'AS-35230', 'HY-15307', 'SY099591', 'DB-103511', 'US10183931, SLx-2119', 'BRD-K88506063-001-01-8', 'Q27269397', '2-[3-[4-[(5-Indazolyl)amino]-2-quinazolinyl]phenoxy]-N-isopropylacetamide', '2-(3-{4-[(1H-indazol-5-yl)amino]quinazolin-2-yl}phenoxy)-N-(propan-2-yl)acetamide', '2-[3-[4-(1H-Indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)acetamide', 'ICQ']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Bortezomib","PubChemCID":"387447","SMILES":"B([C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O","Synonyms":"['Bortezomib', '179324-69-7', 'Bortezomib accord', 'NSC-681239', 'Peptide boronate', 'MLN-341', 'PS 341 (pharmaceutical)', 'UNII-69G8BD63PP', '69G8BD63PP', 'N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE', 'DTXSID3040980', 'CHEBI:52717', 'HSDB 7666', 'MG 341', 'NSC 681239', 'DTXCID1020980', 'BORTEZOMIB (MART.)', 'BORTEZOMIB [MART.]', 'N-((1S)-1-Benzyl-2-(((1R)-1-(dihydroxyboranyl)-3-methylbutyl)amino)-2-oxoethyl)pyrazinecarboxamide', 'N-((1S)-1-benzyl-2-(((1R)-1-(dihydroxyboranyl)-3-methylbutyl)amino)2-oxoethylpyrazinecarboxamide', 'bortezomibum', 'Bortexomib', 'N-((1R)-1-(DIHYDROXYBORYL)-3-methylbutyl)-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide', 'N-((1R)-1-(dihydroxyboranyl)-3-methylbutyl)-N(alpha)-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide', 'N-[(1R)-1-(dihydroxyboranyl)-3-methylbutyl]-N(alpha)-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide', 'Bortezomib for Injection', 'L01XX32', 'Velcade', 'PS-341', 'Bortezomib (PS-341)', 'LDP-341', 'Ps 341', '((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid', '[(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid', 'Boronic acid, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-', 'Bortezomib (Velcade)', 'MG-341', 'CHEMBL325041', 'MFCD09056737', 'NSC681239', 'NCGC00242506-02', 'S1013', 'N-[(1R)-1-(dihydroxyboranyl)-3-methylbutyl]-Nalpha-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide', 'radiciol', 'Pyz-Phe-boroLeu', '(R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butylboronic acid', 'BORTEZOMIB HYDRATE [JAN]', '[(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acid', 'Boronic acid, ((1R)-3-methyl-1-(((2S)-1-oxo-3-phenyl-2-((pyrazinylcarbonyl)amino)propyl)amino)butyl)-', 'Velcade (TN)', 'DPBA', 'CAS-179324-69-7', 'C19H25BN4O4', 'LDP 341', '[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid', 'PROSCRIPT BORONIC ACID', 'Bortezomib [USAN:INN:BAN]', 'Bortezomib hydrate', 'Bortezomib,Velcade', 'LPD 341', 'LPD-341', 'NCGC00168751-01', 'NCGC00181022-01', '((1R)-3-Methyl-1-(((2S)-3-phenyl-2-((pyrazinylcarbonyl)amino)propanoyl)amino)butyl)boronic acid', '[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-boronic acid;Radiciol', '[(1R)-3-Methyl-1-[[(2S)-3-phenyl-2-[(pyrazinylcarbonyl)amino]propanoyl]amino]butyl]boronic acid', 'Bortezomib [USAN]', 'Velcade (Millenium)', 'Bortezomib (Standard)', '3mg0', 'BORTEZOMIB [MI]', 'BORTEZOMIB [INN]', 'BORTEZOMIB [JAN]', '1610526-91-4', 'BORTEZOMIB [HSDB]', 'PS-341 [Bortezomib]', 'BORTEZOMIB [VANDF]', 'BORTEZOMIB [WHO-DD]', 'MLS004774142', 'Bortezomib (JAN/USAN/INN)', 'BORTEZOMIB [EMA EPAR]', 'SCHEMBL192129', 'Bortezomib - Bio-X trade mark', 'GTPL6391', 'BORTEZOMIB [ORANGE BOOK]', 'GLXC-05159', 'EX-A8373', 'Tox21_112630', 'Tox21_112672', 'BDBM50069989', 'HB4036', 'HY-10227R', 'NSC756655', 'AKOS015909706', 'Tox21_112672_1', 'CCG-268449', 'CS-1039', 'DB00188', 'FM19000', 'NSC-756655', 'NCGC00242506-01', 'NCGC00242506-06', 'NCGC00242506-07', 'AS-15721', 'BB164258', 'HY-10227', 'NCI60_029010', 'SMR003500787', 'Bortezomib (Velcade,MG-341,PS-341)?', 'B5741', 'NS00006197', 'SW208077-3', 'D03150', 'EN300-657180', 'AB01273951-01', 'AB01273951-02', 'AB01273951_03', 'Q419319', 'SR-01000939863', 'SR-01000939863-2', 'BRD-K88510285-001-02-0', 'BRD-K88510285-001-11-1', 'BRD-K88510285-001-17-8', 'BRD-K88510285-001-18-6', 'Z2213886907', '((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronicacid', '(R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-6-carboxamido)propanamido)butylboronic acid', '[(1R)-3-methyl-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]butyl]boronic acid', '(1R)-3-Methyl-1-({(2S)-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propanoyl}amino)butylboronic acid, AldrichCPR', '(R)-3-METHYL-1-((S)-3-PHENYL-2-(PYRAZINE-2-CARBOXAMIDO)PROPANAMIDO)BUTAN-2-YLBORONIC ACID', '[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]-butyl]boronic acid', 'Boronic acid, (3-methyl-1-((1-oxo-3-phenyl-2-((pyrazinylcarbonyl)amino)propyl)amino)butyl)-, (S-(R*,S*))-', 'Boronic acid, [(1(R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Tg101348","PubChemCID":"16722836","SMILES":"CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)OCCN4CCCC4","Synonyms":"['Fedratinib', '936091-26-8', 'SAR 302503', 'UNII-6L1XP550I6', '6L1XP550I6', 'DTXSID90239483', 'Benzenesulfonamide, N-(1,1-dimethylethyl)-3-((5-methyl-2-((4-(2-(1-pyrrolidinyl)ethoxy)phenyl)amino)-4-pyrimidinyl)amino)-', 'N-Tert-butyl-3-(5-methyl-2-(4-(2-pyrrolidin-1-yl-ethoxy)-phenylamino)-pyrimidin-4-ylamino)-benzenesulfonamide', 'N-TERT-BUTYL-3-((5-METHYL-2-(4-(2-(PYRROLIDIN-1-YL)ETHOXY)ANILINO(PYRIMIDIN-4-YL)AMINO)BENZENESULFONAMIDE', 'fedratinibum', 'DTXCID10161974', 'L01XE57', 'N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino) pyrimidin-4-ylamino)benzenesulfonamide', 'Tg-101348', 'TG101348', 'SAR302503', 'N-(tert-butyl)-3-((5-methyl-2-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)pyrimidin-4-yl)amino)benzenesulfonamide', 'SAR-302503', 'Fedratinib (SAR302503, TG101348)', 'Inrebic', 'TG 101348', 'N-(1,1-Dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]benzenesulfonamide', 'N-tert-butyl-3-[[5-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)anilino]pyrimidin-4-yl]amino]benzenesulfonamide', 'CHEMBL1287853', '936091-26-8 (free base)', 'N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide', 'N-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzenesulfonamide', 'Fedratinib [USAN]', 'Fedratinib [USAN:INN]', 'TG101348 (SAR302503)', '2TA', 'MFCD12922515', 'FEDRATINIB [MI]', 'FEDRATINIB [INN]', 'Fedratinib (USAN/INN)', 'FEDRATINIB [WHO-DD]', 'Fedratinib (TG101348)', 'TG101348(Fedratinib)?', 'MLS006011155', 'SCHEMBL263741', 'GTPL5716', 'CHEBI:91408', 'EX-A170', 'GLXC-04732', 'HMS3295I03', 'HMS3656L19', 'HMS3744G17', 'HMS3868L03', 'BCP02300', 'BDBM50332294', 'NSC767600', 'NSC800099', 's2736', 'AKOS015842621', 'CCG-264990', 'CS-0052', 'DB12500', 'EX-5961', 'NSC-767600', 'NSC-800099', 'SB14604', 'SDCCGSBI-0654455.P001', 'NCGC00244252-01', 'NCGC00244252-07', '945381-69-1', 'AC-30260', 'AS-16248', 'DA-40258', 'FD151499', 'HY-10409', 'SMR004702929', 'DB-079623', 'NS00071609', 'SW218187-2', 'D10630', 'F17372', 'Q7670147', 'BRD-K12502280-001-01-5', 'BRD-K12502280-001-08-0', 'BRD-K12502280-001-11-4', 'Z2037280076', 'N-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzene-1-sulfonamide', 'SAR302503, N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"PF4708671","PubChemCID":"51371303","SMILES":"CCC1=CN=CN=C1N2CCN(CC2)CC3=NC4=C(N3)C=C(C=C4)C(F)(F)F","Synonyms":"['PF-4708671', 'PF4708671', '2-[[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-6-(trifluoromethyl)-1H-benzimidazole', 'DTXSID10680074', '2-((4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-6-(trifluoromethyl)-1H-benzimidazole', 'DTXCID20630823', '(2-(4-(5-ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-5-(trifluoromethyl)-1H-benzo(d)imidazole', '1255517-76-0', '2-((4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole', 'PF 4708671', 'PF-04708671', '2-[[4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzo[d]imidazole', 'MFCD18086922', '2-{[4-(5-Ethylpyrimidin-4-Yl)piperazin-1-Yl]methyl}-5-(Trifluoromethyl)-1h-Benzimidazole', 'CHEMBL2134202', '2-((4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-6-(trifluoromethyl)-1H-benzo[d]imidazole', 'FBLPQCAQRNSVHB-UHFFFAOYSA-N', 'C19H21F3N6', '2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-1H-benzimidazole; PF 4708671;', '2-{[4-(5-ETHYLPYRIMIDIN-4-YL)PIPERAZIN-1-YL]METHYL}-5-(TRIFLUOROMETHYL)-1H-1,3-BENZODIAZOLE', '5FI', 'MLS006011193', 'GTPL8036', 'SCHEMBL17714406', 'SCHEMBL23964170', 'EX-A248', 'CHEBI:232526', 'GLXC-06320', 'HMS3263P20', 'HMS3651E14', 'HMS3673K17', 'BCP07961', 'Tox21_501279', 'BDBM50543601', 's2163', 'AKOS024457939', 'AKOS025405226', 'CCG-222583', 'CS-1739', '2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-1H-benzimidazole', 'NCGC00261964-01', 'NCGC00263134-01', 'NCGC00263134-08', 'AC-33113', 'AS-16311', 'DA-46660', 'FE101574', 'HY-15773', 'SMR004702962', 'SW220233-1', 'PF 04708671', 'PF-4708671?', 'PF-4708671, >=98% (HPLC)', 'BRD-K14711741-001-02-1', 'BRD-K14711741-001-05-4', 'Q27088333']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Daunorubicin","PubChemCID":"30323","SMILES":"C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)C)O)N)O","Synonyms":"['daunorubicin', 'Daunomycin', '20830-81-3', 'Acetyladriamycin', 'Leukaemomycin C', 'Rubidomycin', 'Daunorubicine', 'Cerubidine', '(+)-Daunomycin', 'DaunoXome', 'Daunorubicinum', 'Cerubidin', 'RP 13057', 'Rubomycin C', 'FI 6339', 'Daunorubicin (INN)', 'NSC-82151', 'Daunarubicinum', 'Daunorrubicina', 'DaunoXome (TN)', 'Daunamycin', '(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione', 'FI-6339', 'FI6339', 'ZS7284E0ZP', '(8S-cis)-8-Acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedione', '5,12-Naphthacenedione,8-acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-', 'DTXSID7022883', 'CHEBI:41977', 'NCGC00024246-05', 'Anthracycline', 'Anthracyline', 'NDC-0082-4155', 'DAUNORUBICIN [INN]', 'Daunorubicinum [INN-Latin]', 'DTXCID402883', 'MLS000069508', 'Daunorubicin [INN:BAN]', 'NSC-83142', 'RCRA waste no. U059', '(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside', '(8S,10S)-8-acetyl-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione', '(8S,10S)-8-acetyl-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione', 'CAS-20830-81-3', 'NSC82151', 'SMR000058559', 'Daunorubicina', 'CCRIS 914', 'SR-01000000033', 'SR-05000001600', 'HSDB 5095', 'NCI-C04693', 'EINECS 244-069-7', 'NSC 83142', 'VS-103', 'BRN 1445583', 'Tocris-1467', 'Daunorubicin(Daunomycin)', 'AI3-52942', '(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride', 'Prestwick3_000487', 'DAUNOMYCIN [IARC]', 'DAUNORUBICIN [MI]', 'CHEMBL178', 'DAUNORUBICIN [HSDB]', 'SCHEMBL3041', 'DAUNORUBICIN [VANDF]', 'EPIRUBICIN IMPURITY D', 'UNII-ZS7284E0ZP', 'BSPBio_000353', 'DAUNORUBICIN [MART.]', '5,12-Naphthacenedione, 8-acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-', 'cid_62770', 'DAUNORUBICIN [WHO-DD]', 'BPBio1_000389', 'GTPL7063', 'BDBM32017', 'EX-A1337A', 'Valrubicin impurity, daunorubicin', 'Daunomycin;RP 13057;Rubidomycin', 'DAUNORUBICIN [ORANGE BOOK]', 'GLXC-23059', 'HMS2089H04', 'HMS2091K06', 'Pharmakon1600-01500223', 'VYXEOS COMPONENT DAUNORUBICIN', 'Tox21_110896', 'BDBM50368352', 'GR-318', 'HY-13062A', 'LMPK13050002', 'MFCD00866340', 'NSC756717', 'Tox21_110896_1', 'CCG-212559', 'CS-2004', 'DB00694', 'MD32002', 'NSC-756717', 'NCGC00024246-06', 'NCGC00024246-07', 'NCGC00024246-09', 'NCGC00024246-10', 'NCGC00024246-12', 'NCGC00024246-15', 'NCGC00024246-18', 'NCGC00025173-01', '(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside', '(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranoside', '(7S,9R)-9-Acetyl-7-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione', '(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione', '5,12-Naphthacenedione, 8-acetyl-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-', 'SBI-0206677.P002', 'AB00514669', 'C01907', 'D07776', 'Epirubicin hydrochloride impurity, daunorubicin-', 'AB00514669-09', 'AB01644616_09', 'AB01644616_10', 'EN300-7479232', 'Q411659', 'SR-01000000033-4', 'SR-05000001600-1', 'SR-05000001600-2', 'BRD-K43389675-001-01-3', 'BRD-K43389675-001-02-1', 'BRD-K43389675-003-02-7', 'BRD-K43389675-003-03-5', 'BRD-K43389675-003-16-7', 'BRD-K43389675-003-20-9', 'EPIRUBICIN HYDROCHLORIDE IMPURITY D [EP IMPURITY]', 'VALRUBICIN IMPURITY, DAUNORUBICIN [USP IMPURITY]', 'DOXORUBICIN HYDROCHLORIDE IMPURITY A [EP IMPURITY]', 'EPIRUBICIN HYDROCHLORIDE IMPURITY, DAUNORUBICIN- [USP IMPURITY]', '(1S,3S)-3-ACETYL-1,2,3,4,6,11-HEXAHYDRO-3,5,12-TRIHYDROXY-10-METHOXY-6,11-DIOXO-1-NAPHTHACENYL 3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-LYXO-HEXOPYRANOSIDE', '(7S,9S)-7-[(2R,4S,5S,6S)-4-azanyl-6-methyl-5-oxidanyl-oxan-2-yl]oxy-9-ethanoyl-4-methoxy-6,9,11-tris(oxidanyl)-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride', '(7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-quinone;hydrochloride', '(7S,9S)-9-acetyl-7-[[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-2-oxanyl]oxy]-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride', '(8S,10S)-8-ACETYL-10-((3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-LYXO-HEXOPYRANOSYL)OXY)-6,8,11-TRIHYDROXY-1-METHOXY-7,8,9,10-TETRAHYDROTETRACENE-5,12-DIONE', '(8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro--6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione', '(8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-n aphthacenedione;Daunomycin', '5,12-NAPHTHACENEDIONE, 8-ACETYL-10-((3-AMINO-2,3,6-TRIDEOXY-.ALPHA.-L-LYXO-HEXOPYRANOSYL))OXY)-7,8,9,10-TETRAHYDRO-6,8,11-TRIHYDROXY-1-METHOXY-, (8S-CIS)-']","Type":"small molecule"},{"Action":"unknown","PerturbationName":"Cyclosporine","PubChemCID":"5284373","SMILES":"CC[C@H]1C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1)[C@@H]([C@H](C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C","Synonyms":"['cyclosporin A', 'Ciclosporin', 'cyclosporine', 'Cyclosporin', '59865-13-3', 'Sandimmune', 'Neoral', 'Cyclosporine A', 'Sandimmun', 'Ciclosporine', 'Ramihyphin A', 'Equoral', 'Gengraf', 'Neoplanta', 'Sang-35', 'Ciclosporina', 'Ciclosporinum', 'Sandimmun Neoral', 'Zinograf ME', 'Consupren', 'Mitogard', 'Optimmune', 'Ciclosporin A', 'Restasis', 'NeuroSTAT', 'Atopica', 'Antibiotic S 7481F1', 'MFCD00274558', 'Ciclosporin [INN]', 'VEVYE', 'SangCyA', 'CSA', 'Cyclosporine microemulsion', '83HN0GTJ6D', 'SDZ-OXL-400', 'MLS001333756', 'CHEBI:4031', 'ANTIBIOTIC S-7481F1', '(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone', 'DTXSID0020365', 'S-Neoral', 'Cipol N', 'Sigmasporin Microoral', 'NSC-290193', 'OL-27-400', 'SDZ-OXL 400', 'DTXCID00365', 'OL 27-400', 'Abrammune', 'Imusporin', 'Seciera', 'Vekacia', 'Papilock Mini', 'Arpimune ME', 'Sandimmune Neoral', 'Ciclosporina Germed', 'Cyclosporine;Ciclosporin', '(R-(R*,R*-(E)))-Cyclic(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-alpha-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl)', 'CYA', 'Cyclo(((E)-(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl)-L-2-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl)', 'SMR000058578', 'Cicloral (antibiotic)', 'Cyclosporine [USAN]', 'Debio088', 'Sang 35', 'Cyclosporine [USAN:USP]', 'UNII-83HN0GTJ6D', 'Ciclosporine [INN-French]', 'Ciclosporinum [INN-Latin]', 'Ciclosporina [INN-Spanish]', 'Sigmasporin', 'Cyclokat', 'Ikervis', 'Papilock', 'Pulminiq', 'Zyclorin', 'CicloMulsion', 'Ciclosporin;', 'CCRIS 1590', 'Ciclosporin DT', 'Consupren S', 'NSC290193', 'Modusik-A', 'HSDB 6881', '1cyn', '2wfj', '4jjm', 'Cipol-N', 'NCGC00016890-01', '(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,2', '(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone', '(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methyl-hex-4-enyl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone', '(R-[R*,R*-(E)])-Cyclic(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-alpha-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl)', 'Cyclo[[(E)-(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl]-L-2-aminobutyryl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl]', 'DRG-0275', 'Prestwick_731', 'CAS-59865-13-3', 'CEQUA', 'VERKAZIA', 'NSC 290193', 'CsA & IFN.alpha.', '1c5f', '2z6w', 'S 7481F1', 'Cyclosporine manufacturer', 'Prestwick2_000435', 'Prestwick3_000435', 'CICLOSPORIN [JAN]', 'Cyclosporin A (Standard)', 'CHEMBL160', 'Sang-2000', 'CYCLOSPORINE [HSDB]', 'CYCLOSPORINE [IARC]', 'CYCLOSPORIN A [MI]', 'SCHEMBL3491', 'SCHEMBL4442', 'CICLOSPORIN [MART.]', 'CYCLOSPORINE [VANDF]', 'Nova-22007', 'BSPBio_000450', 'CICLOSPORIN [WHO-DD]', 'CICLOSPORIN [WHO-IP]', 'Cyclosporin A & IFN.alpha.', 'MLS000028376', 'MLS002153454', 'MLS002207033', 'CYCLOSPORINE [USP-RS]', 'BPBio1_000496', 'GTPL1024', 'Cyclosporine;Ciclosporin;Atopica', 'CHEBI:92233', 'HY-B0579R', 'ATH-002', 'CYCLOSPORINE [GREEN BOOK]', 'OLO-400', 'CB-01-09 MMX', 'CICLOSPORIN [EP MONOGRAPH]', 'CYCLOSPORINE [ORANGE BOOK]', 'Cyclosporine; Ciclosporin; Atopica', 'GLXC-04692', 'GLXC-06801', 'HMS1569G12', 'HMS2089A09', 'HMS2096G12', 'HMS2230M14', 'HMS3713G12', 'Cyclosporin A - Bio-X trade mark', 'CYCLOSPORINE [USP IMPURITY]', '1,11-cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(E)-(2S,3R,4R)-2-amino-3-hydroxy-N,4-dimethyloct-6-enoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine]', '30-Ethyl-33-(1-hydroxy-2-methyl-hex-4-enyl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31undecaaza-cyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone', '30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone', '30-ethyl-33-[(4E)-1-hydroxy-2-methylhex-4-en-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone', 'Cyclo(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-((3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl)-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methylleucyl)', 'EX-A4110', 'HY-B0579', 'CYCLOSPORINE [USP MONOGRAPH]', 'Tox21_110667', 'Tox21_301849', 'BDBM50022815', 'CICLOSPORINUM [WHO-IP LATIN]', 'DE-076', 'ST-603', 'Cyclosporin A, >=98.5% (TLC)', 'AKOS015969287', 'AKOS015994720', 'Tox21_110667_1', 'CCG-208184', 'DB00091', 'FC20749', 'KS-1257', 'SDCCGSBI-0050230.P004', 'NCGC00093704-12', 'NCGC00164258-01', 'NCGC00164258-02', 'NCGC00164258-03', 'NCGC00255232-01', 'BC164336', 'BP-28432', 'Cyclo(L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-((3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methylleucyl)', 'OL-27400', 'SBI-0050230.P003', 'C2408', 'M01532', 'Cyclosporin A, VETRANAL(TM), analytical standard', 'Q367700', 'SR-01000780563', 'SR-01000780563-3', 'BRD-K03222093-001-01-8', 'BRD-K13533483-001-03-0', 'Ciclosporin, European Pharmacopoeia (EP) Reference Standard', 'Cyclosporin A, from Tolypocladium inflatum, >=95% (HPLC), solid', 'Cyclosporine, United States Pharmacopeia (USP) Reference Standard', 'Ciclosporin for system suitability, European Pharmacopoeia (EP) Reference Standard', 'Cyclosporin A, from Tolypocladium inflatum, BioReagent, for molecular biology, >=95%', 'Cyclosporine, Pharmaceutical Secondary Standard; Certified Reference Material', '(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhex-4-en-1-yl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-bis(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecone', '(R-(R*,R*-(E)))-CYCLIC(L-ALANYL-D-ALANYL-N-METHYL-L-LEUCYL-N-METHYL-L-LEUCYL-N-METHYL-L-VALYL-3-HYDROXY-N,4-DIMETHYL-L-2-AMINO-6-OCTENOYL-L-.ALPHA.-AMINOBUTYRYL-N-METHYLGLYCYL-N-METHYL-L-LEUCYL-L-VALYL-N-METHYL-L-LEUCYL)', '104250-72-8', '30-Ethyl-33-((E)-1-hydroxy-2-methyl-hex-4-enyl)-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,28-octamethyl-1,4,7,10,13,16,19,22,25,28,31undecaaza-cyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"Lenalidomide","PubChemCID":"216326","SMILES":"C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N","Synonyms":"['Lenalidomide', '191732-72-6', 'Revimid', '3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione', '2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-', 'CDC 501', 'CDC-501', '3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione', 'Lenalidomida', 'NSC-747972', 'UNII-F0P408N6V4', 'DTXSID8046664', 'CHEBI:63791', 'ENMD 0997', 'HSDB 8220', 'F0P408N6V4', 'SYP-1512', '1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline', 'DTXCID6026664', 'NSC 747972', 'LENALIDOMIDE (MART.)', 'LENALIDOMIDE [MART.]', 'IMiD3 cpd', 'lenalidomidum', 'L04AX04', 'NSC703813', '(3RS)-3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione', 'Revlimid', 'CC-5013', 'Lenalidomide (CC-5013)', 'IMiD3', '3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione', 'CC 5013', 'Lenadoamide', 'C13H13N3O3', 'Revlimid (TN)', 'MFCD07772307', '(3S)-3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione', 'NCGC00167491-01', 'Lenalidomide [USAN]', '3-(4-amino-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione', '3-(4-Amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione', 'CAS-191732-72-6', 'Lenalidomide?', 'Lenalidomide [USAN:INN:BAN]', '443912-14-9', 'ENMD-0997', 'IMID-5013', 'CDC-5013', 'ALBB-015321', 'Lenalidomide (Standard)', 'LENALIDOMIDE [MI]', 'LENALIDOMIDE [INN]', 'LENALIDOMIDE [JAN]', 'CHEMBL848', 'Revlimid (TN) (Celgene)', 'LENALIDOMIDE [VANDF]', 'SCHEMBL32978', 'MLS003899194', 'LENALIDOMIDE [WHO-DD]', 'GTPL7331', 'Lenalidomide (JAN/USAN/INN)', 'LENALIDOMIDE [EMA EPAR]', '3-(4-Amino-1-oxo-2-isoindolinyl)piperidine-2,6-dione', 'SCHEMBL26646478', 'BDBM65454', 'HY-A0003R', 'Lenalidomide - Bio-X trade mark', '3-(7-Amino-3-oxo-1H-isoindol-2-yl)-piperidine-2,6-dione', 'BCPP000186', 'HMS3654G07', 'HMS3674C05', 'LENALIDOMIDE [ORANGE BOOK]', 'BCP01390', 'CIA27191', 'HY-A0003', 'Revlimid, Lenalidomide, CC-5013', 'Tox21_112492', 'AC-914', 'NSC747972', 's1029', 'STK639603', '2,6-Piperidinedione, 3-(4-amino-1,3-dihydro-1-oxo-2H- isoindol-2-yl)-', 'AKOS005146276', 'AKOS005174869', 'Tox21_112492_1', 'BCP9000847', 'CCG-264781', 'CS-0125', 'DB00480', 'FL24864', 'KS-1207', 'SB66166', 'NCGC00167491-02', 'NCGC00167491-03', 'NCGC00167491-04', 'BL164614', 'BP-27972', 'SMR002529986', 'SY047646', 'NS00003666', 'SW218084-2', 'D04687', 'EN300-118706', 'AB01273975-01', 'AB01273975-02', 'AB01273975_03', 'Q425681', 'SR-01000883999', 'SR-01000883999-1', '1-Oxo-4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole', 'BRD-A17883755-001-06-1', 'Z1515385074', '2, 3-(4-amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-', '3-(4-amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)-2,6-dioxopiperidine', '3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione;1-Oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline;CC-5013', '3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione;Oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline;CC-5013', '4-amino-2-(6-hydroxy-2-oxo-2,3,4,5-tetrahydropyridin-3-yl)-2,3-dihydro-1H-isoindol-1-one']","Type":"small molecule"},{"Action":"not found","PerturbationName":"Ku","PubChemCID":"56951715","SMILES":"[Rf]","Synonyms":"['rutherfordium', '53850-36-5', 'Rf', 'rutherfordium atom', 'unnilquadium', 'kurchatovium', 'rutherfordio', '104Rf', 'CHEBI:33346', 'DTXSID30718944', 'Q27115613', 'Ku']","Type":"small molecule"},{"Action":"inhibit","PerturbationName":"TBCA","PubChemCID":"16760346","SMILES":"C1=C(C(=C(C(=C1Br)Br)Br)Br)/C=C/C(=O)O","Synonyms":"['934358-00-6', 'tetrabromocinnamic acid', 'casein kinase II inhibitor III', '(2E)-3-(2,3,4,5-tetrabromophenyl)prop-2-enoic acid', 'TBCA cpd', 'TBCA', '(E)-3-(2,3,4,5-Tetrabromophenyl)acrylic acid', 'Casein Kinase II Inhibitor III, TBCA', 'CHEMBL270724', '3-(2,3,4,5-tetrabromophenyl)acrylic acid', '(E)-3-(2,3,4,5-tetrabromophenyl)prop-2-enoic acid', '1130169-61-7', 'SCHEMBL526548', 'SCHEMBL526550', 'GTPL5941', 'GLXC-01626', 'HMS3229C22', 'EX-A7579', 'BDBM50347922', 'AKOS027470139', 'CCG-206827', 'SDCCGSBI-0086740.P004', 'MS-28533', 'DB-257904', 'HY-110052', 'CS-0032876', 'G14104', '(e)-3-(2,3,4,5-tetrabromophenyl) acrylic acid', 'Q27075735', 'Casein Kinase II Inhibitor III, TBCA - CAS 934358-00-6']","Type":"small molecule"}]